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Martin Pacesa

@MartinPacesa • 5,914 subscribers

Assistant Professor at the University of Zurich. 🖥️ protein design, machine learning🤖, crystallography💎, cryoEM🔬. Avid weirdness connoisseur 🎩

Shorts

Have you ever wanted to design protein binders with ease? Today we present 𝑩𝒊𝒏𝒅𝑪𝒓𝒂𝒇𝒕, a user-friendly and open-source pipeline that allows to anyone to create protein binders de novo with high experimental success rates. Bruno Correia Sergey Ovchinnikov

Have you ever wanted to design protein binders with ease? Today we present 𝑩𝒊𝒏𝒅𝑪𝒓𝒂𝒇𝒕, a user-friendly and open-source pipeline that allows to anyone to create protein binders de novo with high experimental success rates. Bruno Correia Sergey Ovchinnikov

300,832 views

Exciting to see our protein binder design pipeline BindCraft published in its final form in nature ! This has been an amazing collaborative effort with Lennart, Christian Schellhaas, Sergey Ovchinnikov, Bruno Correia and many other amazing lab members and collaborators.

Exciting to see our protein binder design pipeline BindCraft published in its final form in nature ! This has been an amazing collaborative effort with Lennart, Christian Schellhaas, Sergey Ovchinnikov, Bruno Correia and many other amazing lab members and collaborators.

61,511 views

Just before the New Year: BindCraft v1.5! Please fill out this form to request new features and help us make BindCraft even better.

Just before the New Year: BindCraft v1.5! Please fill out this form to request new features and help us make BindCraft even better.

41,242 views

Thanks to everyone for the amazing response to BindCraft! 🔥🚀🖥️ Feel free to DM me or write on Github if encounter targets where the pipeline fails to generate binders, we want to use the feedback to improve it! P.S: here is a "helicopter" binder against DerF21 dimer

Thanks to everyone for the amazing response to BindCraft! 🔥🚀🖥️ Feel free to DM me or write on Github if encounter targets where the pipeline fails to generate binders, we want to use the feedback to improve it! P.S: here is a "helicopter" binder against DerF21 dimer

33,061 views

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My favourite sequential folding video, featured on the homepage

My favourite sequential folding video, featured on the homepage

18,143 views • 1 month ago

Today in nature we present the results of our exploration of the soluble protein universe and the design of functional soluble membrane proteins with Casper Goverde Nico Goldbach Bruno Correia 1/6

Today in nature we present the results of our exploration of the soluble protein universe and the design of functional soluble membrane proteins with Casper Goverde Nico Goldbach Bruno Correia 1/6

138,442 views • 2 years ago

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