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@NassirGhaemi • 1,079 subscribers

Scientific and humanistic psychiatry from Nassir Ghaemi MD MPH.

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Serotonin withdrawal syndrome, a controversial but significant issue, affects over 50% of patients on SRIs after a year or more of treatment. Early studies suggesting low rates are likely flawed. #Psychiatry #SRI #MentalHealth

Serotonin withdrawal syndrome, a controversial but significant issue, affects over 50% of patients on SRIs after a year or more of treatment. Early studies suggesting low rates are likely flawed. #Psychiatry #SRI #MentalHealth

Psychiatry Letter

27,727 просмотров • 3 месяцев назад

Patients on SSRIs get better. So do patients on placebo. Depression often resolves on its own. Controlling for that — no meaningful added benefit from the drug.

Patients on SSRIs get better. So do patients on placebo. Depression often resolves on its own. Controlling for that — no meaningful added benefit from the drug.

Psychiatry Letter

22,718 просмотров • 3 месяцев назад

SRIs have a Cohen's d of 0.3 for depression. For anxiety? It's 0.6 — double the benefit. These aren't antidepressants. They're anti-anxiety drugs marketed as antidepressants.

SRIs have a Cohen's d of 0.3 for depression. For anxiety? It's 0.6 — double the benefit. These aren't antidepressants. They're anti-anxiety drugs marketed as antidepressants.

Psychiatry Letter

21,598 просмотров • 3 месяцев назад

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