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Jude Wells

@_judewells • 1,539 subscribers

Encode AI for Science Fellow (Pillar VC / Imperial College London) Protein Design, PhD in machine learning for structural biology at UCL

Shorts

TED: The Encyclopedia of Domains now published in Science Magazine discovering and annotating 314 MILLION protein domains in the AlphaFold database. joint work of @CATH_Gene3D and PSIPRED here at UCL.

TED: The Encyclopedia of Domains now published in Science Magazine discovering and annotating 314 MILLION protein domains in the AlphaFold database. joint work of @CATH_Gene3D and PSIPRED here at UCL.

68,144 görüntüleme

Excited to announce the release of our open-source protein family language model, ProFam-1, designed to generate functional protein variants and predict fitness using in-context example sequences. 1/n

Excited to announce the release of our open-source protein family language model, ProFam-1, designed to generate functional protein variants and predict fitness using in-context example sequences. 1/n

15,278 görüntüleme

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Just submitted some designed proteins to Adaptyv Bio EGFR binder competition. My strategy was Chai1 optimization on a diverse set of known EGFR binders shown below. Lower 2 are antibody FABs (necitumumab and panitumumab) which are too large for the competition requirements so...

Just submitted some designed proteins to Adaptyv Bio EGFR binder competition. My strategy was Chai1 optimization on a diverse set of known EGFR binders shown below. Lower 2 are antibody FABs (necitumumab and panitumumab) which are too large for the competition requirements so...

21,313 görüntüleme • 1 yıl önce

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