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Journal of Cell Biology

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The Journal of Cell Biology (JCB) publishes peer-reviewed research on all aspects of cellular structure and function. Est. 1955 - @RockUPress

Shorts

New study from Youfang Zhou, Xianfeng Wang, et al. in the DengLab @tulanemedicine show that induced #polyploidy acts as an intrinsic cellular stress, reprogramming epithelial cells to promote motility and phagocytic behaviors.

New study from Youfang Zhou, Xianfeng Wang, et al. in the DengLab @tulanemedicine show that induced #polyploidy acts as an intrinsic cellular stress, reprogramming epithelial cells to promote motility and phagocytic behaviors.

11,166 просмотров

Takami Sho, Li Yu et al. Tsinghua University unveil migratory autolysosome disposal, a response to #lysosome damage where cells expel LAMP1-LC3 positive structures via autolysosome exocytosis, requiring #autophagy machinery, SNARE proteins, and cell #migration.

Takami Sho, Li Yu et al. Tsinghua University unveil migratory autolysosome disposal, a response to #lysosome damage where cells expel LAMP1-LC3 positive structures via autolysosome exocytosis, requiring #autophagy machinery, SNARE proteins, and cell #migration.

16,958 просмотров

Going steady for maturity: a subset of CD63-rich #endosomes partner with #microtubule-associated #septins, which promote maturation to multivesicular bodies/late endosomes by inhibiting their motility. New from @SeptinLab Drexel University College of Arts and Sciences UVa Cell Biology:

Going steady for maturity: a subset of CD63-rich #endosomes partner with #microtubule-associated #septins, which promote maturation to multivesicular bodies/late endosomes by inhibiting their motility. New from @SeptinLab Drexel University College of Arts and Sciences UVa Cell Biology:

13,435 просмотров

.Sho Suzuki (he/him) et al. propose that Vps13 may play a critical role in supplying #lipids to #endosomes, ensuring continuous ESCRT-mediated sorting during MVB biogenesis. From our Inter-Organelle Contacts collection:

.Sho Suzuki (he/him) et al. propose that Vps13 may play a critical role in supplying #lipids to #endosomes, ensuring continuous ESCRT-mediated sorting during MVB biogenesis. From our Inter-Organelle Contacts collection:

12,015 просмотров

Using a combination of modern cell biology techniques, including #trafficking assays, #CRISPR, and secretomics, Pereira, Stalder, David Gershlick et al. Cambridge University reveal that the exocyst complex has a fundamental role in protein secretion.

Using a combination of modern cell biology techniques, including #trafficking assays, #CRISPR, and secretomics, Pereira, Stalder, David Gershlick et al. Cambridge University reveal that the exocyst complex has a fundamental role in protein secretion.

16,269 просмотров

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Fuentes and Marin (Zach Marin) et al. Bewersdorf Lab Yale Cell Biology use super-resolution microscopy to reveal that Rtn4 oligomers possess a unique nanoscale organization that helps shape elliptical ER tubules. Jonathan Tyson, Ph.D. David Baddeley #Membrane

Fuentes and Marin (Zach Marin) et al. Bewersdorf Lab Yale Cell Biology use super-resolution microscopy to reveal that Rtn4 oligomers possess a unique nanoscale organization that helps shape elliptical ER tubules. Jonathan Tyson, Ph.D. David Baddeley #Membrane

Journal of Cell Biology

19,275 просмотров • 2 лет назад

Pfitzner, Zivkovic et al. Roux Lab UNIGE_en characterize a novel membrane-bound ESCRT-III copolymer initiated by Vps60 that are spatially & biochemically distinct from classical Snf7-based ESCRT-III filaments in vitro & may have diverse functions in vivo.

Pfitzner, Zivkovic et al. Roux Lab UNIGE_en characterize a novel membrane-bound ESCRT-III copolymer initiated by Vps60 that are spatially & biochemically distinct from classical Snf7-based ESCRT-III filaments in vitro & may have diverse functions in vivo.

Journal of Cell Biology

14,657 просмотров • 2 лет назад

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