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Lifespan Magazine & The Lifespan Show provide evidence-based information so you can live your longest, healthiest life while supporting medical research 🧬💪

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Blocking growth hormone signaling in mice extends maximum lifespan 29% and increased strength. More evidence that peptides like GHK-Cu that boost GH signaling may put us in “abundance mode,” which would not be a good long-term strategy for health & longevity 🧵

Blocking growth hormone signaling in mice extends maximum lifespan 29% and increased strength. More evidence that peptides like GHK-Cu that boost GH signaling may put us in “abundance mode,” which would not be a good long-term strategy for health & longevity 🧵

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How can a tree live for 1,000 years? Lifespan recently visited Shunkaen Bonsai Museum in Tokyo, where world-renowned master Kunio Kobayashi preserves trees that have been cared for by generations of bonsai masters Their longevity may come from something trees do exceptionally well: renewal A centuries-old bonsai is not made entirely of centuries-old tissue. Its leaves, roots, bark, and vascular tissues are repeatedly replaced. Plant stem cells, found in regions called meristems, continue producing new growth throughout life Research on ancient trees suggests these stem-cell systems can remain active for centuries, supported by powerful repair and stress-response mechanisms That may be relevant to human longevity. We also depend on stem cells to renew blood, skin, muscle, and other tissues. As we age, that regenerative capacity declines Bonsai do not preserve every old part. They preserve the ability to renew. Perhaps this is due to epigenetic stability that preserves stem cell function

How can a tree live for 1,000 years? Lifespan recently visited Shunkaen Bonsai Museum in Tokyo, where world-renowned master Kunio Kobayashi preserves trees that have been cared for by generations of bonsai masters Their longevity may come from something trees do exceptionally well: renewal A centuries-old bonsai is not made entirely of centuries-old tissue. Its leaves, roots, bark, and vascular tissues are repeatedly replaced. Plant stem cells, found in regions called meristems, continue producing new growth throughout life Research on ancient trees suggests these stem-cell systems can remain active for centuries, supported by powerful repair and stress-response mechanisms That may be relevant to human longevity. We also depend on stem cells to renew blood, skin, muscle, and other tissues. As we age, that regenerative capacity declines Bonsai do not preserve every old part. They preserve the ability to renew. Perhaps this is due to epigenetic stability that preserves stem cell function

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Born around 1832, Jonathan the tortoise has certainly been alive since before railways & telegraph, and is officially the oldest land animal ever He shows us what biology is capable of: almost no risk of diseases for the first 190 years of life. Imagine that 👏 The Associated Press Guinness World Records

Born around 1832, Jonathan the tortoise has certainly been alive since before railways & telegraph, and is officially the oldest land animal ever He shows us what biology is capable of: almost no risk of diseases for the first 190 years of life. Imagine that 👏 The Associated Press Guinness World Records

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Can’t wait for you to see the new episodes of Lifespan. Sign up & receive early access & bonus material. Launch April 2026 ✌️

Can’t wait for you to see the new episodes of Lifespan. Sign up & receive early access & bonus material. Launch April 2026 ✌️

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