Gary Siuzdak's banner

Gary Siuzdak

@kadzuis • 6,243 subscribers

Scientist, heal thyself. Designing #METLIN & #XCMS to identify active natural products, lipids, metabolites, drugs… https://t.co/WtRlKrV5Zs

Shorts

70% of the peaks in LC/MS data is noise, whether it is derived from endogenous or exogenous molecules. An interesting outcome from our recent analysis of the MS/MS data from over 930,000 endogenous and exogenous molecules in #METLIN at 0eV. Only 30% total peaks from molecular ions and 70% from ISF, this 70% might explain the "dark matter" Nature Methods

70% of the peaks in LC/MS data is noise, whether it is derived from endogenous or exogenous molecules. An interesting outcome from our recent analysis of the MS/MS data from over 930,000 endogenous and exogenous molecules in #METLIN at 0eV. Only 30% total peaks from molecular ions and 70% from ISF, this 70% might explain the "dark matter" Nature Methods

35,243 просмотров

Videos

Anya Rossi

sweetdream.ai

SweetDream.ai•Sponsored•Livecam

Watch Anya Live

Anya is streaming live right now! Join her private show and enjoy exclusive content.

Exclusive private shows

1.2k viewers online

Private Show

Join now for exclusive access

Free preview available • Premium content

Tens of thousands of papers/books on #masspec or #metabolomics, now a book with “Metabolomics" AND "Mass Spectrometry" You can freely download the book at and A hardcopy will be available in the coming days. Thoughts welcome

Tens of thousands of papers/books on #masspec or #metabolomics, now a book with “Metabolomics" AND "Mass Spectrometry" You can freely download the book at and A hardcopy will be available in the coming days. Thoughts welcome

27,201 просмотров • 2 лет назад

Mass spectrometry data re-interpretation Nature Metabolism. #METLIN's 931K molecular stds data was mined at 0eV CE showing >70% LCMS peaks are in-source fragments (ISF). Shifting how small molecule LCMS data is deciphered #metabolomics ACS Analytical Chemistry Journals @MartinGiera

Mass spectrometry data re-interpretation Nature Metabolism. #METLIN's 931K molecular stds data was mined at 0eV CE showing >70% LCMS peaks are in-source fragments (ISF). Shifting how small molecule LCMS data is deciphered #metabolomics ACS Analytical Chemistry Journals @MartinGiera

22,235 просмотров • 2 лет назад

Downloadable #METLIN-CCS library Nature Methods just released 185K CCS values on 27,633 molecular stds. Multiple ion types MH+, MNa+, M–H, dimers pos/neg ioniz., not a bad #AI resource. Great collaboration w Biemann laureate Dr. Erin Baker Am Soc for Mass Spec @MacCossLab Bruker Ryan Roitman-Waters Metabolon, Inc.

Downloadable #METLIN-CCS library Nature Methods just released 185K CCS values on 27,633 molecular stds. Multiple ion types MH+, MNa+, M–H, dimers pos/neg ioniz., not a bad #AI resource. Great collaboration w Biemann laureate Dr. Erin Baker Am Soc for Mass Spec @MacCossLab Bruker Ryan Roitman-Waters Metabolon, Inc.

23,899 просмотров • 3 лет назад

Free #Metabolomics & #massspec #AMMS short course Scripps Research(Sept 3, 10, 17, 24 10a-11:30a PT each Tuesday). Covering MassSpec, Metabolomics, and some Proteomics. Zoom and limited in-person seating Sponsored by Agilent Technologies Waters Corporation Info & register at The course will cover September 3rd 10-11:30a Pacific Time • Introduction to Mass Spectrometry & Metabolomics September 10th 10-11:30a Pacific Time • Proteomics Segue • Targeted Metabolomics • Untargeted Metabolomics September 17th 10-11:30a Pacific Time • XCMS Data Processing • METLIN 935K Database • In-Source Fragmentation LC/MS Data Annotation • XCMS-METLIN Integration September 24th 10-11:30a Pacific Time • Metabolite Identification • Activity Metabolomics

Free #Metabolomics & #massspec #AMMS short course Scripps Research(Sept 3, 10, 17, 24 10a-11:30a PT each Tuesday). Covering MassSpec, Metabolomics, and some Proteomics. Zoom and limited in-person seating Sponsored by Agilent Technologies Waters Corporation Info & register at The course will cover September 3rd 10-11:30a Pacific Time • Introduction to Mass Spectrometry & Metabolomics September 10th 10-11:30a Pacific Time • Proteomics Segue • Targeted Metabolomics • Untargeted Metabolomics September 17th 10-11:30a Pacific Time • XCMS Data Processing • METLIN 935K Database • In-Source Fragmentation LC/MS Data Annotation • XCMS-METLIN Integration September 24th 10-11:30a Pacific Time • Metabolite Identification • Activity Metabolomics

11,134 просмотров • 2 лет назад

Больше нет контента для загрузки