Lucas Farnung's banner

Lucas Farnung

@LucasFarnung • 2,692 subscribers

Assistant Professor @HarvardCellBio. Transcription & Chromatin; Biochemistry, X-ray & Cryo-EM. Views are my own.

Shorts

🧬🎉 Our new chromatin remodeling study is out: We reveal three states of human CHD1 and identify a novel "anchor element" that interacts with the acidic patch—conserved among remodelers. Our structures clarify mechanisms of remodeler recruitment! Link:

🧬🎉 Our new chromatin remodeling study is out: We reveal three states of human CHD1 and identify a novel "anchor element" that interacts with the acidic patch—conserved among remodelers. Our structures clarify mechanisms of remodeler recruitment! Link:

13,372 просмотров

Videos

Anya Rossi

sweetdream.ai

SweetDream.ai•Sponsored•Livecam

Watch Anya Live

Anya is streaming live right now! Join her private show and enjoy exclusive content.

Exclusive private shows

1.2k viewers online

Private Show

Join now for exclusive access

Free preview available • Premium content

Ever wondered how transcription choreographs histone modifications? Our work reveals the basis of co-transcriptional H3K36me3 by SETD2. We visualize how a histone writer coordinates with the transcription machinery! This is the magnus opus of Jon Markert

Ever wondered how transcription choreographs histone modifications? Our work reveals the basis of co-transcriptional H3K36me3 by SETD2. We visualize how a histone writer coordinates with the transcription machinery! This is the magnus opus of Jon Markert

75,981 просмотров • 1 год назад

Extremely excited to share this work by Maik Engeholm out in Molecular Cell: Chd1 engages overlapping dinucleosomes, and collaborates with FACT to restore and remodel overlapping dinucleosomes. Patrick Cramer

Extremely excited to share this work by Maik Engeholm out in Molecular Cell: Chd1 engages overlapping dinucleosomes, and collaborates with FACT to restore and remodel overlapping dinucleosomes. Patrick Cramer

23,519 просмотров • 1 год назад

🔬 New from the Farnung Lab: We have established a fully in vitro reconstituted chromatin replication system and we report the first cryo-EM snapshots of the human replisome engaging nucleosomes. 🧬✨

🔬 New from the Farnung Lab: We have established a fully in vitro reconstituted chromatin replication system and we report the first cryo-EM snapshots of the human replisome engaging nucleosomes. 🧬✨

16,487 просмотров • 1 год назад

Our story on the complete Rpd3S-nucleosome complex is now online on Biorxiv: We visualize the S. cerevisiae Rpd3S complex bound to a nucleosome including the "evasive" Ume1 subunit! Congrats, Jon Markert! Thank you Seychelle Vos for a great collaboration.

Our story on the complete Rpd3S-nucleosome complex is now online on Biorxiv: We visualize the S. cerevisiae Rpd3S complex bound to a nucleosome including the "evasive" Ume1 subunit! Congrats, Jon Markert! Thank you Seychelle Vos for a great collaboration.

11,761 просмотров • 3 лет назад

Больше нет контента для загрузки