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Shalin Mehta

@mattersOfLight • 1,310 subscribers

intrigued by light, logic and life. Platform Leader, Computational Microscopy at CZ Biohub (@czbiohub). Views my own.

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🔬🤖Excited to share our new preprint on robust virtual staining of key organelles! ✨ Virtual staining and segmentation of nuclei and cell membranes in phase images can significantly accelerate image-based screens and developmental studies. 🔍 Current virtual staining models often struggle with nuisance variations in label-free input and don't generalize well to new cell types. We’re releasing our training protocols that lead to robust models and enable few-shot generalization. 🔧 Stay tuned for our revamped codebase with weights and example data, coming soon! 👏🧫🐟 Huge shoutout to Ziwen Liu, Eduardo Hirata-Miyasaki, my team Chan Zuckerberg Biohub Network (Soorya, Johanna, Christian, Talon Chandler, Ivan Ivanov), and the teams of Manuel Leonetti, Carolina Arias, and Adrian Jacobo for this fun collaboration! #VirtualStaining #DL #CellBiology #Zebrafish

🔬🤖Excited to share our new preprint on robust virtual staining of key organelles! ✨ Virtual staining and segmentation of nuclei and cell membranes in phase images can significantly accelerate image-based screens and developmental studies. 🔍 Current virtual staining models often struggle with nuisance variations in label-free input and don't generalize well to new cell types. We’re releasing our training protocols that lead to robust models and enable few-shot generalization. 🔧 Stay tuned for our revamped codebase with weights and example data, coming soon! 👏🧫🐟 Huge shoutout to Ziwen Liu, Eduardo Hirata-Miyasaki, my team Chan Zuckerberg Biohub Network (Soorya, Johanna, Christian, Talon Chandler, Ivan Ivanov), and the teams of Manuel Leonetti, Carolina Arias, and Adrian Jacobo for this fun collaboration! #VirtualStaining #DL #CellBiology #Zebrafish

20,185 Aufrufe

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🔬🤖Excited to share our new preprint on robust virtual staining of key organelles! ✨ Virtual staining and segmentation of nuclei and cell membranes in phase images can significantly accelerate image-based screens and developmental studies. 🔍 Current virtual staining models often struggle with nuisance variations in label-free input and don't generalize well to new cell types. We’re releasing our training protocols that lead to robust models and enable few-shot generalization. 🔧 Stay tuned for our revamped codebase with weights and example data, coming soon! 👏🧫🐟 Huge shoutout to Ziwen Liu, Eduardo Hirata-Miyasaki, my team Chan Zuckerberg Biohub Network (Soorya, Johanna, Christian, Talon Chandler, Ivan Ivanov), and the teams of Manuel Leonetti, Carolina Arias, and Adrian Jacobo for this fun collaboration! #VirtualStaining #DL #CellBiology #Zebrafish

🔬🤖Excited to share our new preprint on robust virtual staining of key organelles! ✨ Virtual staining and segmentation of nuclei and cell membranes in phase images can significantly accelerate image-based screens and developmental studies. 🔍 Current virtual staining models often struggle with nuisance variations in label-free input and don't generalize well to new cell types. We’re releasing our training protocols that lead to robust models and enable few-shot generalization. 🔧 Stay tuned for our revamped codebase with weights and example data, coming soon! 👏🧫🐟 Huge shoutout to Ziwen Liu, Eduardo Hirata-Miyasaki, my team Chan Zuckerberg Biohub Network (Soorya, Johanna, Christian, Talon Chandler, Ivan Ivanov), and the teams of Manuel Leonetti, Carolina Arias, and Adrian Jacobo for this fun collaboration! #VirtualStaining #DL #CellBiology #Zebrafish

20,185 Aufrufe • vor 2 Jahren

🔬🤖Excited to share permittivity tensor imaging (PTI), a label-free computational imaging module for high-resolution 3D imaging of dry mass and 3D orientation of organelles, cells, and tissues! 🧬🧫 Just published in Nature Methods Shout out to Li-Hao Yeh , Talon Chandler, Ivan Ivanov, Janie Byrum, Bryant , Syuan-Ming Guo, Cameron Foltz at Chan Zuckerberg Biohub Network, Peter Kazansky lab ORC Southampton, BruceConklin lab at Gladstone Institutes, and May Han lab at Stanford Medicine. 🧵1/n

🔬🤖Excited to share permittivity tensor imaging (PTI), a label-free computational imaging module for high-resolution 3D imaging of dry mass and 3D orientation of organelles, cells, and tissues! 🧬🧫 Just published in Nature Methods Shout out to Li-Hao Yeh , Talon Chandler, Ivan Ivanov, Janie Byrum, Bryant , Syuan-Ming Guo, Cameron Foltz at Chan Zuckerberg Biohub Network, Peter Kazansky lab ORC Southampton, BruceConklin lab at Gladstone Institutes, and May Han lab at Stanford Medicine. 🧵1/n

16,611 Aufrufe • vor 2 Jahren

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