Riccardo De Santi

We’re bringing natural-language control to any scientific generator. We are very excited to introduce LLM-to-Flow Distillation (LFD), a method to adapt scientific generators to high-level natural-language discovery goals. Starting from textual goals like “design peptides with promising anticancer activity” or “design small molecules binding to the D2 dopamine receptor”, LFD distills high-level goal-related knowledge from LLMs into scientific generators through iterative DPO on LLM-generated sub-goals. 🔥 LFD does not need task-specific proxy rewards, works with any frontier LLM via API-access, and outperforms state-of-the-art reward-guided methods such as FlowGRPO and DiffusionNFT on held-out computational evaluations. (1/6)