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Thomas N. Seyfried

@tnseyfried • 56,150 subscribers

Author of Cancer as a Metabolic Disease. Boston College professor. #cancer will be managed with metabolic therapies.

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We now have the scientific evidence confirming that genetic mutations are not the primary cause of cancer. The primary cause of cancer is damaged mitochondria coupled to compensatory and upregulated fermentation of glucose and glutamine (full clip:

We now have the scientific evidence confirming that genetic mutations are not the primary cause of cancer. The primary cause of cancer is damaged mitochondria coupled to compensatory and upregulated fermentation of glucose and glutamine (full clip:

152,950 Aufrufe

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Our recent paper provides the missing piece to Otto Warburg's central theory that cancer is a mitochondrial metabolic disease. We now know how to kill the beast without toxicity.

Our recent paper provides the missing piece to Otto Warburg's central theory that cancer is a mitochondrial metabolic disease. We now know how to kill the beast without toxicity.

Thomas N. Seyfried

1,022,471 Aufrufe • vor 1 Jahr

The cancer cells have been signaling to us for decades that they're fermenting. Cut off their two fermentable fuels - glucose and glutamine - and the cancer cells will die. (Full clip: Link to our recent paper:

The cancer cells have been signaling to us for decades that they're fermenting. Cut off their two fermentable fuels - glucose and glutamine - and the cancer cells will die. (Full clip: Link to our recent paper:

Thomas N. Seyfried

500,213 Aufrufe • vor 1 Jahr

The life expectancy following standard of care for brain cancer is the same today as it was in 1926. Once you know that cancer is a disease driven by glucose and glutamine fermentation and that the very treatments you're using increase glucose and glutamine fermentation...

The life expectancy following standard of care for brain cancer is the same today as it was in 1926. Once you know that cancer is a disease driven by glucose and glutamine fermentation and that the very treatments you're using increase glucose and glutamine fermentation...

Thomas N. Seyfried

255,636 Aufrufe • vor 1 Jahr

All major cancers have damaged mitochondria, preventing them from sufficiently converting oxygen into energy. Instead, cancer cells ferment glucose and glutamine, which acidifies the micro environment around the tumor. This acidity reduces efficacy of common cancer therapies

All major cancers have damaged mitochondria, preventing them from sufficiently converting oxygen into energy. Instead, cancer cells ferment glucose and glutamine, which acidifies the micro environment around the tumor. This acidity reduces efficacy of common cancer therapies

Thomas N. Seyfried

161,125 Aufrufe • vor 1 Jahr

All clinical studies of cancer should be targeting glucose and glutamine while the patient is in nutritional ketosis, because the science tells us that's what we should do. The cancer cells themselves are telling us this is what we should do. (Full clip

All clinical studies of cancer should be targeting glucose and glutamine while the patient is in nutritional ketosis, because the science tells us that's what we should do. The cancer cells themselves are telling us this is what we should do. (Full clip

Thomas N. Seyfried

78,552 Aufrufe • vor 1 Jahr

There are some hospitals now opening "medicine for cancer survivors," because there are patients experiencing a new realm of health issues as a result of surviving these horrific, toxic treatments. However, with metabolic therapy we can manage cancer without toxicity.

There are some hospitals now opening "medicine for cancer survivors," because there are patients experiencing a new realm of health issues as a result of surviving these horrific, toxic treatments. However, with metabolic therapy we can manage cancer without toxicity.

Thomas N. Seyfried

70,303 Aufrufe • vor 1 Jahr

All 6 glioblastoma patients who maintained a low GKI for 6+ months lived at least 33 months. Of the 12 patients who did not keep a low GKI, just 1 lived to 30 months. Read the full study: Watch the full video:

All 6 glioblastoma patients who maintained a low GKI for 6+ months lived at least 33 months. Of the 12 patients who did not keep a low GKI, just 1 lived to 30 months. Read the full study: Watch the full video:

Thomas N. Seyfried

55,471 Aufrufe • vor 1 Jahr

Our recent study describing how cancer cells ferment the amino acid glutamine caused many people to ask which dietary habits will lower glutamine levels in the body. However, while diet can greatly reduce blood glucose levels, there is no dietary practice that can meaningfully lower glutamine. Additionally, glutamine is essential in several body processes, including the immune system. While intermittent glutamine inhibition via glutamine targeting drugs can be effective against cancer, glutamine targeting should be done carefully and under the supervision of a knowledgeable caregiver, as described in our recent paper: We are now working to determine the best dosing, timing, and scheduling of such diet-drug combined therapies. (full video clip:

Our recent study describing how cancer cells ferment the amino acid glutamine caused many people to ask which dietary habits will lower glutamine levels in the body. However, while diet can greatly reduce blood glucose levels, there is no dietary practice that can meaningfully lower glutamine. Additionally, glutamine is essential in several body processes, including the immune system. While intermittent glutamine inhibition via glutamine targeting drugs can be effective against cancer, glutamine targeting should be done carefully and under the supervision of a knowledgeable caregiver, as described in our recent paper: We are now working to determine the best dosing, timing, and scheduling of such diet-drug combined therapies. (full video clip:

Thomas N. Seyfried

59,321 Aufrufe • vor 1 Jahr

This is why the results of tumor biopsies are largely irrelevant toward managing cancer

This is why the results of tumor biopsies are largely irrelevant toward managing cancer

Thomas N. Seyfried

62,075 Aufrufe • vor 1 Jahr

6 out of 18 glioblastoma (brain cancer) patients maintained a low GKI for 6+ months. All 6 lived at least 33 months. At the time the study was published, 1 of them was still alive 84 months after diagnosis. Of the 12 who did not maintain a low GKI, just 1 lived more than 30 months. Read the full study: Watch an excerpt from the full interview:

6 out of 18 glioblastoma (brain cancer) patients maintained a low GKI for 6+ months. All 6 lived at least 33 months. At the time the study was published, 1 of them was still alive 84 months after diagnosis. Of the 12 who did not maintain a low GKI, just 1 lived more than 30 months. Read the full study: Watch an excerpt from the full interview:

Thomas N. Seyfried

51,737 Aufrufe • vor 1 Jahr

Cancer patients who still wish to use standards of care can first use metabolic therapy to reduce the acidification of the tumor microenvironment. This allows standard treatments like chemotherapy, radiation, and immunotherapy to be much more effective.

Cancer patients who still wish to use standards of care can first use metabolic therapy to reduce the acidification of the tumor microenvironment. This allows standard treatments like chemotherapy, radiation, and immunotherapy to be much more effective.

Thomas N. Seyfried

57,077 Aufrufe • vor 1 Jahr

Some professionals recognize that cancer cells ferment in the cytoplasm, but few acknowledge that all major forms of cancer also ferment inside the mitochondria. If we are to make meaningful progress in cancer management, we must understand it all begins in the mitochondria. Watch the full interview: Read the full publication:

Some professionals recognize that cancer cells ferment in the cytoplasm, but few acknowledge that all major forms of cancer also ferment inside the mitochondria. If we are to make meaningful progress in cancer management, we must understand it all begins in the mitochondria. Watch the full interview: Read the full publication:

Thomas N. Seyfried

38,575 Aufrufe • vor 1 Jahr

The Key to Managing Cancer: Transition the body over to fatty acids and ketones while you simultaneously target the two fuels driving the dysregulated cell growth. Full video clip:

The Key to Managing Cancer: Transition the body over to fatty acids and ketones while you simultaneously target the two fuels driving the dysregulated cell growth. Full video clip:

Thomas N. Seyfried

41,416 Aufrufe • vor 1 Jahr

Cancer patients, or anybody for that matter, can calculate their GKI by measuring their blood/glucose level (in millimolar) and dividing it by their blood/ketone level (in millimolar).

Cancer patients, or anybody for that matter, can calculate their GKI by measuring their blood/glucose level (in millimolar) and dividing it by their blood/ketone level (in millimolar).

Thomas N. Seyfried

31,465 Aufrufe • vor 1 Jahr

I was also indoctrinated into believing that cancer was a genetic disease until I actually did the research myself. (full clip:

I was also indoctrinated into believing that cancer was a genetic disease until I actually did the research myself. (full clip:

Thomas N. Seyfried

28,901 Aufrufe • vor 1 Jahr

How can cancer be a disease of somatic mutations (which the National Cancer Institute claims) when many cancers have been found to have no mutations at all?

How can cancer be a disease of somatic mutations (which the National Cancer Institute claims) when many cancers have been found to have no mutations at all?

Thomas N. Seyfried

27,203 Aufrufe • vor 1 Jahr

Press Pulse Protocol, which you can read about in our paper (link tweeted earlier this week), calls for cancer patients to reduce glucose and elevate ketones. This intervention initiates numerous anti-cancer benefits.

Press Pulse Protocol, which you can read about in our paper (link tweeted earlier this week), calls for cancer patients to reduce glucose and elevate ketones. This intervention initiates numerous anti-cancer benefits.

Thomas N. Seyfried

27,043 Aufrufe • vor 1 Jahr

"Regrettably, standard [Glioblastoma] therapeutics are not designed to take advantage of the metabolic vulnerabilities of cancer cells; instead, they focus on DNA repair mechanisms. In fact, as an unintended consequence of non-specific cell damage, radiotherapy has been shown to induce detrimental metabolic changes and inflammation in the tumor microenvironment..." Read the full paper: Watch the full video clip:

"Regrettably, standard [Glioblastoma] therapeutics are not designed to take advantage of the metabolic vulnerabilities of cancer cells; instead, they focus on DNA repair mechanisms. In fact, as an unintended consequence of non-specific cell damage, radiotherapy has been shown to induce detrimental metabolic changes and inflammation in the tumor microenvironment..." Read the full paper: Watch the full video clip:

Thomas N. Seyfried

23,496 Aufrufe • vor 1 Jahr

No gene - BRCA1, 2 and P53 included - has been found to be 100% penetrant in causing cancer. (full clip

No gene - BRCA1, 2 and P53 included - has been found to be 100% penetrant in causing cancer. (full clip

Thomas N. Seyfried

21,827 Aufrufe • vor 1 Jahr

Derek Lee, fifth year PhD candidate in Professor Seyfried's lab, discusses practical tactics for using Ketogenic Metabolic Therapy to combat cancer. Watch full clip: Read Derek Lee's recent publication:

Derek Lee, fifth year PhD candidate in Professor Seyfried's lab, discusses practical tactics for using Ketogenic Metabolic Therapy to combat cancer. Watch full clip: Read Derek Lee's recent publication:

Thomas N. Seyfried

13,237 Aufrufe • vor 1 Jahr