
This Week in Startups
@twistartups • 106,795 subscribers
Your thrice weekly deep dive into startups, markets, & tech | Hosted by @jason and @lons We're hiring! Apply: [email protected] or [email protected]!
Videos

This is the electric plane Elon dreamed of! Anders Forslund of Heart Aerospace joins @jason to show off their electric plane, which used up just $5 worth of power for a full 20-minute trip. Could this change short-haul flights? What locations would these flights best be used at?
This Week in Startups4,519,688 Aufrufe • vor 12 Tagen

When Bank of America wouldn’t let Jason take out $20K from his account for a Vegas trip… he decided it was time for a new financial partner. So he called three banks and asked each one to send him $10K in $2 bills. One delivered… and became his new bank. It’s the classic “Van Halen rider” test. If you still see Brown M&Ms in the proverbial bowl, the venue didn’t read your rider, and doesn’t really value your business. A vital lesson in picking your partners with diligence. (cc: @jason, Lon Harris, Van Halen, Bank of America)
This Week in Startups863,250 Aufrufe • vor 5 Monaten

J-Cal says the exact dollar amount at which money stops mattering: $10 million. Park it, earn 5%, and you're clearing half a million a year without lifting a finger. You can go do whatever you want or nothing at all. That's real F-U money. Everything past that is just keeping score.
This Week in Startups471,460 Aufrufe • vor 3 Monaten

Have you been mass buying Mac Minis for your new OpenClaw🦞 workflows? One man who skated to puck is Alex Cheema, founder of EXO Labs! He joins TWiST today to show @jason how his open source software helps users connect all of their Mac Minis. Check out how you can start running your own AI compute cluster!
This Week in Startups680,613 Aufrufe • vor 7 Monaten

Sam Altman walked into YC, offering founders $1M in free tokens for a slice of equity. Jason's advice: run. OpenAI is watching your token usage, ranking the winners, then shipping the top 5 as native features. Get off the frontier models, use open source, and own your data. @jason
This Week in Startups196,766 Aufrufe • vor 2 Monaten

“Bitcoin is the most efficient market in history. We built the same thing for intelligence.” Const left Google Brain to build something Big Tech wouldn’t touch: open, permissionless AI that can be mined like Bitcoin. On a special TWiST deep dive, Bittensor’s co-founder breaks down the subnet economy, how subnets are making open models even cheaper to run, and why he doesn’t sell a token, but participation. cc: const, Openτensor Foundaτion, @jason, Lon Harris 0:00 The origin of Bittensor (and the name Const) 10:48 Northwest Registered Agent - Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at 13:55 From Bitcoin mining to mining intelligence 19:33 DigitalOcean - Head to to start building on DigitalOcean's AI-Native Cloud today — and cut your AI workload costs by up to 50%. 30:17 Odoo - The all-in-one business platform. Get started for free at 32:37 What is a subnet? 33:35 Forcing honest inference from bad actors 37:14 Building a subnet is harder than it looks 40:42 Understanding dTAO 51:57 Where the registration TAO actually goes 1:02:57 All about the Conviction "rug pull" 1:15:19 How Const is making himself irrelevant 1:17:33 The "Buy One TAO" philosophy 🎥 Watch the full episode here 👇
This Week in Startups44,690 Aufrufe • vor 26 Tagen

Chamath: “Facebook, Tesla, Google… they almost had an allergic reaction to the traditional software stack. They refused to use it.” Find out why he raised a $135M Series A to redefine development, giving every enterprise the opportunity to build and maintain their own software without the $4T in consultants and middleware that usually comes with it… in the debut episode of TWiST All Star Summer 2026. 0:00 It's TWiST All-Star Summer! 0:44 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at and use code TWIST for 10% off! 3:21 Chamath's origin story 7:54 Tom Sawyer entrepreneurship 11:29 Shopify - Turn those What If's into sales with the ecommerce platform powering millions of businesses. Sign up for your $1-per-month trial today at 16:25 The $5 trillion software market 21:06 LinkedIn Jobs - Hire right, the first time. Post your first job and get $100 off towards your job post at 25:00 Building "a co-founder for every human" 31:51 Northwest Registered Agent - Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at 35:00 How product development lost its way 45:00 Regulated industries are the beachhead 50:00 Raising the $135M Series A 55:00 8090's "System on a Chip" model 1:04:44 What to tell your kids about AI cc: Chamath Palihapitiya, @jason, 8090 🎥 Watch the full episode here 👇
This Week in Startups110,050 Aufrufe • vor 2 Monaten

Wild conspiracy theory: Anthropic got sabotaged by its own backers… Amazon flagged a jailbreak to the government to subvert a rival it secretly competes with. @jason isn't buying it. "There's no grand conspiracy here." The real story is much more boring, and more believable… What do you think?
This Week in Startups114,485 Aufrufe • vor 2 Monaten

Alex Karp and Palantir's 9-point "AI Sovereignty" manifesto grabbed the world's attention earlier this week... but Jason has been saying basically the same thing since February (!) on All-In. Just compare Karp's opener or The Original JCal: KARP: "Sovereignty is the precondition for choice, relinquishing sovereignty transfers the future choices of your institution to others." JASON: "Intelligence sovereignty is you can't tell me what to think. You can't use your AI to analyze my photos, emails, messages, and tell me how to interpret the world." Basically, whoever controls the model controls the outcome, and if that's not you... it's someone else.
This Week in Startups83,646 Aufrufe • vor 2 Monaten

Here’s why OpenHome creator Jesse Leimgruber says, if you’re still prompting OpenClaw🦞 on a screen, you’re falling behind! The whole point of AI agents is that they can do things for you in the real world. But what’s the point if you’re still interacting with them exclusively through a laptop. That’s why Jesse created a smart speaker that allows you to interact vocally with your agent from any room in your home, 24/7. Having an agent listen in on your conversations, and learn all about you and your life in context, opens up an entirely new level of productivity… and might just save your Valentine’s Day as well.
This Week in Startups209,839 Aufrufe • vor 6 Monaten

Chamath spent $4M building a private research team, just so he could stay informed on energy. He figured: If you’re going to allocate real capital, you need a prepared mind and high-quality information. This sort of research is expensive, so he systematized it. Now, for $1K/year, any investor can get the same analyst digest that he’s using. Learn more about how he got thousands of subscribers to pay for his information infrastructure through “Learn With Me.” cc: Chamath Palihapitiya, @jason
This Week in Startups83,984 Aufrufe • vor 2 Monaten

Jason’s warning about Sam Altman, in his own words: He's going to steal or liberate or copy… pick your term of art… any partner's product. He will stab any partner in the back, even if it was Apple." The pattern: OpenAI partners with you, learns the playbook, then builds the thing themselves. Apple, NVIDIA, now hardware. Sam doesn't partner. He competes. If you're working with OpenAI, you're a future competitor. @jason
This Week in Startups74,671 Aufrufe • vor 2 Monaten

This founder’s viral plea to Trump: Don’t kill eCommerce 🇺🇸📦 Steven Borrelli Steven Borrelli, founder of Cuts, joins @jason and alex 🏴☠️🇺🇸🇺🇦 to break down the massive blow new tariffs and the end of the 321 exemption could deliver to bootstrapped American brands. 🔹 145% tariffs = business-killing math — no brand can survive that kind of hit. 🔹 CUTS ships from Mexico using 321 rules — but that loophole ends May 2. 🔹 No time to pivot: Moving production takes 6–9 months — not 6–9 days. 🔹 Tariffs ≠ higher prices — they mean no sales at all. 🔹 Borrelli says: “We’re living the American Dream — don’t forget the bootstrappers.” This is a must-watch for anyone building (or buying from) American eComm brands.
This Week in Startups408,283 Aufrufe • vor 1 Jahr

HBO is spending a rumored $5.6 BILLION on this new Harry Potter series but Jason says… it’s actually a smart bet. The “Potter” show reportedly costs $100 million PER EPISODE. That’s around 20x more costly than Season 1 of “Game of Thrones”! How could HBO Max subscriptions alone possibly make that money back. On TWiST, @jason notes that the lifetime value of a hardcore Harry Potter fan is well above $1000. If this show creates 5 million die hard “Potter” fanatics, it earns that money back just from HBO Max subscriptions, let alone theme park visits, merch, new books, video games, and beyond. Dig deep into the economics of IP and how a big investment of front could pay off over generations of fandom on TWiST. cc: @jason, Lon Harris
This Week in Startups146,668 Aufrufe • vor 5 Monaten