Yair Einhorn
@yaireinhorn • 19,177 subscribers
Science and Innovation. I’m laser-focused on BioTech, Pharma, Gene Editing & CRISPR. Occasional thoughts on Stocks, Financial Markets and the Global Economy.
Shorts
Videos
This interview of Jake Van Naarden $LLY head of corporate business development, by Angelica Peebles - CNBC’s excellent Pharma reporter, has demonstrated once again just how far-sighted Eli Lilly’s strategy really is and how it helps Eli Lilly to strengthen its dominance in the BioTech and Pharma ecosystem. I was especially interested to learn more about the rationale behind Eli Lilly’s staggering deal-making pace and that there is much more to come M&A-wise. Definitely worth your time! $XBI
Yair Einhorn24,285 次观看 • 6 天前
I would strongly advise every American leader and policymaker to listen carefully to David R. Liu - the most important scientist and innovator of our lifetime and the person who invented both Base editing & Prime editing - the 2 top leading modalities of Gene editing, when he describes in 60 Minutes the grave danger which the American BioTech ecosystem is facing due to insufficient federal funding. America is already losing its technological and innovative edge! $BEAM $PRME
Yair Einhorn172,336 次观看 • 6 个月前
IMO the most important scientific event this week was the publication of David R. Liu’s new Nature article 🧵👇in which he presented a new and promising Gene Editing modality named PERT - Prime Editing-mediated Readthrough of premature termination codons. This new modality - which uses Prime Editing to converted a regular tRNA gene into a highly optimized suppressor tRNA thus enabling permanent readthrough of premature stop codons, could potentially provide a one-time curative treatment for countless nonsense mutations which are responsible for almost one-third of all human genetic diseases! Here is an excellent lecture by Prof. David Liu - one of the most important scientists and innovators of our lifetime and the person who invented both Base editing and Prime editing - the 2 top leading modalities of Gene Editing, in which he throughly explains this huge scientific breakthrough. $PRME $BEAM
Yair Einhorn62,189 次观看 • 6 个月前
7/I’m fully aware that many - including myself, were expecting much better financial results from $CRSP & $VRTX launch of CASGEVY. Nevertheless, here is HHS secretary Robert F. Kennedy Jr’s recent statement regarding his unequivocal support in CRISPR & Gene Editing therapies in which he specifically mentioned CASGEVY. In my opinion this is super important and positive for the future of both CASGEVY and the Gene Editing field in general.
Yair Einhorn101,867 次观看 • 1 年前
One of the most accurate descriptions of the unbearable situation - in which many Gene Therapies and CRISPR Gene Editing therapies fail to reach patients only due to economical and regulatory hurdles 🧵👇, can be found in this statement - which was made during the recent FDA's Cell and Gene Therapy roundtable, by Prof. David R. Liu the inventor of Base and Prime Editing and the Co-founder of $BEAM & $PRME. During his excellent presentation Prof. Liu emphasised the many challenges facing the field including the lack of commercial potential in many cases due to the small number of patients and the need to approve each treatment for one of the 10,000 different rare genetic diseases separately. According to Prof Liu if the sufficient support will be provided by the government - both regulatory and financially, the BioTech and Pharma ecosystem would be able to generate personalised and customised genetic treatments for 1,000 patients each year by 2030, but most importantly would be able to unlock and pave the way for many more patients and treatments down the road. It’s time to accelerate and bring hope to millions of patients and their families worldwide!
Yair Einhorn37,673 次观看 • 4 个月前
Here is an excellent interview of Dr. Scott Gottlieb, MD 🇺🇸 - the former FDA commissioner on Squawk Box, in which Dr. Gottlieb wonderfully explains the root causes which have led BioTech and big Pharma companies to shift drug discovery to China, the threat that the Chinese BioTech ecosystem poses to the U.S. one 🧵👇and what policy steps are needed in order to level the playing field for early drug discovery. Excellent conversation which is definitely worth listening to! $XBI
Yair Einhorn59,753 次观看 • 8 个月前
Here is an excellent conversation of Dr. Scott Gottlieb, MD 🇺🇸 - the former FDA commissioner with Squawk Box’s Becky Quick, in which Dr. Gottlieb discuss the ongoing clinical research & the regulatory efforts made by the FDA in order to find cures for more than 10,000 different rare genetic diseases which affects the lives of more the 30 million Americans and of many millions more worldwide. A very interesting part of this discussion is Dr. Gottlieb’s description of the huge progress made over the past few years in the Gene Therapy and Gene Editing field - including the use of Base Gene Editing by $BEAM and $VERV. Dr. Gottlieb also wonderfully explains - in laymen’s terms the difference between the different genetic delivery modalities such as AAVs and LNPs. Excellent conversation which is definitely worth listening to! $XBI
Yair Einhorn32,265 次观看 • 5 个月前
🚨WOW! The FDA’s new and promising initiative - regulatory flexibilities for Cell and Gene therapies, is a direct result of the recent Cell & Gene Therapy Roundtable 🧵👇 that was hosted 6 months ago by FDA commissioner Dr. Marty Makary and the director of the FDA’s Center for Biologics Evaluation and Research (CBER) Vinay Prasad MD MPH, in which top industry leaders and scientists shared their views about how to accelerate the R&D process and innovation in the 🇺🇸 BioTech and Pharma ecosystem. It is great to see that this important meeting bore fruit and helped not only to shape the future of the American BioTech ecosystem for years to come but also provided huge hope for patients with genetic diseases worldwide!
Yair Einhorn25,019 次观看 • 4 个月前
Here is David R. Liu’s excellent explanation about a recent and historic moment in human medicine - when a personalised and custom-made genetic base editing treatment was used to cure a new born baby named KJ which suffered from an incurable genetic disease. In his fascinating conversation with Walter Isaacson, David Liu - the winner of the 2025 Breakthrough Prize in Life Sciences and one of the top leading scientists & innovators of our lifetime, explained the science and the process behind creating the treatment which cured KJ’s genetic disease. We are fortunate to live in one of the most exciting and innovative times in human history! If you want to read more - I recommend reading my attached 🧵👇
Yair Einhorn49,754 次观看 • 1 年前
Here is a much needed dose of optimism by David R. Liu about the huge potential of Gene Editing & how it is changing our lives. The remarkable advancement in the Gene editing field & specifically in Base Editing - $BEAM & Prime Editing $PRME is providing hope to so many patients!
Yair Einhorn40,162 次观看 • 9 个月前
On a day in which stock markets around the world are collapsing - let us all take 4 minutes to watch something inspiring that will help us all to remember what BioTech is all about! Here is the amazing Alyssa - a young British teenager who was the first person to ever receive a Base Editing treatment for Leukaemia Cancer which led to a complete remission! 🧵👇Alyssa spoke in honor of Professor David R. Liu - the inventor of Base Editing platform which literally saved her life, when he received the 2025 #BreakthroughPrize in the Life Sciences. BioTech isn’t just about the numbers but actually about changing and saving people’s lives. Let us not forget that!
Yair Einhorn50,026 次观看 • 1 年前
Elon Musk Neuralink IMO Neuralink’s attempt to treat vision loss is an historical moment in human history - No less & I’m super excited to see how this plays out. Every time I’m amazed by the scale of innovation that you & the Neuralink team are generating in our lives. Godspeed Elon!
Yair Einhorn17,354 次观看 • 4 个月前
A new power which threatens the dominance of the American BioTech ecosystem is raising fast in the east. CNN's Will Ripley explains how new & innovative Chinese Biotech companies pose a threat in almost the same way that DeepSeek has done to 🇺🇸 AI. The 🇨🇳 dragon is awake! $XBI
Yair Einhorn39,024 次观看 • 1 年前
Massimo CRISPR GLENN🧬🧠👽💪🏻📈 Here’s CNBC’s great piece which explains in layman’s terms what exactly is CRISPR-Cas9, interviews its co-inventor & Nobel prize winner Emmanuelle Charpentier, how $CRSP transformed this Gene Editing tool into the first ever FDA approved therapy - CASGEVY & its future plans $XBI
Yair Einhorn16,848 次观看 • 6 个月前
It’s heartbreaking to hear David R. Liu - the winner of the 2025 Breakthrough Prize in Life Sciences and one of the top leading scientists & innovators of our lifetime, describes during his conversation with Walter Isaacson the irreversible damages and the crisis caused from the loss of federal support of science in the US which jeopardise not only the recent clinical gene editing breakthroughs achieved in this field but the entire American dominance in Life sciences and technological innovation! The latest decision of the Trump administration and Elon Musk specifically to cut $4B yearly from all of NIH R&D grants to American universities will effect both science & medicine in the U.S and perhaps even worldwide. $XBI 🧵👇
Yair Einhorn24,719 次观看 • 11 个月前
For those on #Twitter interested in #BioTech, #CRISPR & #GeneEditing - here’s a must lecture given by one the top leading #scientists & #innovators of our time - David R. Liu, in which he explains the #Science & the future applications of #BaseEditing & #PrimeEditing. $BEAM $PRME
Yair Einhorn44,771 次观看 • 3 年前