A Golgi apparatus protein in a cell videoed through... a microscope. The Golgi is saturated to show the vesicles trafficking around the cell. #CellBiologyshow more

A cancer cell videoed through a microscope. It has... 3 nuclei (magenta). The powerhouse/overlords of the cell, mitochondria, are also shown (green). #CellBiologyshow more

A melanoma cancer cell videoed through a microscope. DNA... in the nucleus (yellow), mitochondria (cyan), and VASP (magenta) are shown. #CellBiologyshow more

A cell videoed through a microscope. DNA (cyan), mitochondria... (yellow), and VASP (magenta) are shown. #CellBiologyshow more

A cell dividing into two daughter cells videoed through... a microscope. Chromosomes are labeled in pink. Technique: differential interference microscopy (DIC) and fluorescence. #CellBiologyshow more

Wrapping our #Top10Countdown with a bang! At #1 is... 2023 Smart Biology's new immersive animations. Capturing the top spot is the Golgi ribbon animation. #biology #3D #Golgi #animation #education #EdTechshow more

Four cancer cells displaying continuous membrane blebbing videoed through... a DIC microscope. No, these cells are not dying. #CellBiologyshow more

Chromosomes in the nucleus of a cancer cell during... cell division. A maximum projection (left) and a color projection (right) are shown. Yes. Mistakes were made. #CellBiologyshow more

Keep up with our #Top10Countdown! 2023 Smart Biology introduces... new eye-popping animations. #3 is the captivating Golgi Apparatus! #biology #3D #animation #education #scienceiscool #educationinnovationshow more

The same patterns. From atoms to galaxies. This is... what “as above, so below” looks like when you put a single cell under a microscopeshow more

" Absolutely enthralling animation from SmartBiology3D! Seeing the Golgi... apparatus come to life with immersive 3D animations helps both students and educators alike. Truly a top-notch educational tool. " Thank you Raffaele Di Giacomo, PhD . Grateful. Learn more atshow more

Let’s take a closer look at this protein structure... determined using AlphaFold2. This protein structure is part of a huge molecular structure in the human body. More than a thousand proteins form a pore through the membrane surrounding the cell nucleus. Animation: ©Terezia Kovalova/The Royal Swedish Academy of Sciences #NobelPrizeshow more

#FluorescenceFriday #cellbiology #immunology #Actin dynamics at the immunological synapse... (IS) between a Jurkat T cell and an antigen-presenting coverslip, as seen by total internal reflection structured illumination microscopy (TIRF-SIM). John Hammer's group #NIH used our TIRF-SIM to show that formins rearrange inward flowing actin filaments from the outer lamellipodial band of the IS into circumferential arcs that establish the peripheral supramolecular activation cluster, which in turn concentrates T cell receptor microclusters at the center of the IS.show more

BREAKING: Philippines becomes the first country in Southeast Asia... to commercially launch Starlink Direct-to-Cell through a mobile network. Globe has secured regulatory approval to offer Starlink Direct-to-Cell service nationwide.show more

From the ER to outside the cell in 5... minutes - interested in visualizing membrane trafficking in live animals? Check out new paper Developmental Cell Congrats to @CarolinaCamelo6, Raphael Schleutker, @theajacobs_, Dominique Förster + twitterless colleagues Universität Münstershow more

The most detailed 3D reconstruction of a cell ever... created. Blows my mind every time. But what exactly are we looking at here? The average human cell contains: ~ 15-20 total distinct organelle types, totalling between ~1-10 million working together per cell. All these nano-machines in the cell are made up of proteins. ~ 8,000-10,000 distinct types of unique proteins, adding up to between 40 million - 10 trillion total proteins making up all those cellular systems. ~ 10,000 - 15,000 distinct types of RNA shuttling information around the cell, totalling up to ~10 million RNA molecules moving around the cell simultaneously. ~ Billions of Lipid molecules packed together into the cell membrane, which is also packed tightly with millions more protein-based nano-machines. And let's not forget billions of lines of DNA information to build and run it all. That's TRILLIONS of of individual molecular pieces working together to make a single cell function. That means there is more complexity in a single cell than humanity's largest cities. And people still believe this wasn't Divinely Designed. This is God's Glory on Display. But to make the point. A cell couldn't have evolved from some nebulous simpler "protocell" because even the simplest cells still require massive complexity. The "simplest" cell ever created was engineered by scientists knocking out pieces of a functional cell until it stopped functioning. Here is what they found is the absolute necessary minimal requirements of a cell to function: - Over ~531,000 lines of coded DNA information - 473 total genes to create hundreds of unique protein products (they later added 19 genes back in because the cell was so weak) - Hundreds of thousands of total proteins all working together - Extensive regulatory networks guiding all these interactions If the cell doesn't have all these systems in place, from the start... it doesn't live. Cell rely on an intricate network of complex systems, which are themselves built from complex interconnected pieces woven together into an incomprehensibly complex web of functionilty. Only intelligence has ever been observed creation vast interconnected systems like this. Life was clearly Created. It couldn't happen any other way.show more

(1/11) Excited to share the brand-new cell division preprint... from the lab! In this manuscript, chemical biology (in a collaboration with Ryan Nett Ryan’s lab) meets the cell biology (our lab). Harmala alkaloids regulate cell division planes in plantsshow more

Just a normal cell going through cell division…… Wait!!!... What???!!! It was not so normal after all! I guess we have to study membrane blebs now…. The data said so.show more

#FluorescenceFriday #cellbiology #bioart The actin cytoskeleton at 60 nm... resolution and 3 frames/min, and its association with early endosomes (Rab5a, green), as seen in a COS-7 cell by photoactivated nonlinear structured illumination microscopyshow more