Reconstruction of a larval zebrafish brain using 2,000 individually... labeled neurons. Credit to Michael Kunst. #ZebrafishZundayshow more

Imaging the endocardium of the heart in a two-day-old... zebrafish embryo. Credit to Dr Anjalie Schlaeppi. #ZebrafishZundayshow more

Immune cell response to spinal cord injury in a... zebrafish larva. Credit to Becker Lab CRTDresden 😷. #ZebrafishZundayshow more

Happy Valentine! Check out Current Biology & find out... how sensory neurons taste bacterial metabolites in the CSF & secrete compounds to enhance host survival during brain infections. 8 years of work & paper I am the most proud of. Cheers to Yale Zebrafish Phenotyping Core!show more

Our kind of fireworks: fruit fly neurons stacked in... a rapid succession of rainbow colors. This video shows a small sampling of the more than 135,000 neurons in a typical fruit fly's brain, imaged by researchers at our Janelia Research Campus using multicolor flipout technique 🎆show more

Brain cell communication seen in action. Scientists have captured... the millisecond fast process of brain cell communication using advanced imaging. Teams in Berlin and the US used rapid freezing techniques on mouse and human neurons to observe neurotransmitter release and vesicle recycling, revealing key steps and proteins involved. This could help understand brain diseases.show more

You’re looking at neurons growing and connecting in real... time 🧠. A 65-hour recording of hippocampal activity in a rat brain. The hippocampus plays a crucial role in memory and learning. In this footage, neurons extend their dendrites and axons, building and reshaping connections across days. Capturing this process live offers a rare view into how neural circuits form and reorganize. Why this matters ⬇️ 1️⃣It’s a continuous, multi-day recording of living hippocampal neurons under the microscope 2️⃣You can clearly see dendritic branching and network formation 3️⃣It reveals the dynamic processes that drive brain development and plasticity Observing growth at this resolution helps researchers understand how neurons connect—and how disruptions in these processes might contribute to neurological or psychiatric conditions. Credit to Louis Romet and Dr. Christophe Leterrier for the videoshow more

Learn how to combine a deep learning model for... pose estimation to perform a 3D reconstruction using two cameras 📸show more

E11 Bio is excited to unveil PRISM technology for... mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves. We discovered a new cell barcoding approach exceeding comparable methods by more than 750x. This is the heart of PRISM. We integrated this capability with microscopy and AI image analysis to automatically trace neurons at high resolution and annotate them with molecular features. This is a key advance towards economically viable brain mapping - 95% of costs stem from neuron tracing. It is also an important step towards democratizing neuron tracing for everyday neuroscience. Solving these problems is critical for curing brain disorders, building safer and human-like AI, and even simulating brain function. In our first pilot study, we acquired a unique dataset in mouse hippocampus. Barcodes improved the accuracy of tracing genetically labelled neurons by 8x – with a clear path to 100x or more. They also permit tracing across spatial gaps – essential for mitigating tissue section loss in whole-brain scaling. Using molecular annotation, we uncover an intriguing feature of synaptic organization, demonstrating how PRISM can be used for systematic discovery 🧵show more

michael kay using a pair of glasses to stir... his tea is the craziest thing ive ever seenshow more

this is actually how your brain looks like when... you learn a new thing. every time you struggle to learn something new or work on a new skill, your neurons form strong links and weaken the ones you no longer use. so that mental pain of learning, is actually reshaping your brain.show more

🔥🚨BREAKING: A petri dish filled with human brain cells... just learned to how to play DOOM Scientists at Cortical Labs have successfully trained a cluster of approximately 200,000 living human neurons, grown on a microelectrode array chip, to play the classic 3D video game DOOM.show more

using all of my brain power to port it... to vrc. couldn't get it 1 to 1 thoshow more

Facial reconstruction of a 2,000-year-old Maeotian man from Myskhako,... in the Northwest Caucasus. The Maeotians were direct ancestors of the modern Circassian people. They maintained close contacts with the Sauromatians, Sarmatians, and Bosporans.show more

For most of neuroscience history (until the late 1980s/early... 1990s), neurons were treated as the brain’s only decision-makers. That idea is changing. Astrocytes, once considered passive support cells, are now recognized as global regulators of brain state. They don’t encode individual thoughts or actions. Instead, they integrate activity across huge numbers of synapses and adjust how neural networks behave over time. By releasing modulatory signals and tracking slow changes in activity, astrocytes influence: -Alertness vs. fatigue -Stress vs. calm -Motivation vs. disengagement Importantly, they can shift brain function without rewiring neurons, by tuning the environment neurons operate in. The brain isn’t just wired. It’s regulated, and astrocytes play a central role in that regulation.show more

🚨Iranian scientists build lab-grown artificial brain from living human... neurons Iran has mastered the technology for growing nerve cells outside the human body 🔸 Living neurons create synapses and learn like a real human brain 🔸 The new technology is up to 1 million times more energy-efficient than silicon microchips 🔸 It also shows a major increase in processing speed The breakthrough puts Iran in the global race for organoid intelligenceshow more

A stroke can destroy brain cells within minutes, often... leaving people with long‑term problems in movement, memory, or speech. But scientists may have found a way to help the brain heal itself. In studies of mice, researchers injected stem cells into areas of the brain damaged by stroke. These stem cells began turning into early‑stage brain cells, and many later developed into active neurons that connected with surrounding tissue. The treatment did more than just grow cells.show more

A traditional method to separate the lees from the... wine, using a candle to judge the clarity of the flowing wine and stop at the appropriate level of haze.🍷✨ 🎥 : Credit to the Ownershow more

DRAW TO ANIMATION!! Summary of the bases of figurative... draw, have in mind the three elements to make a draw: -The brain, mind. -The eyes, view. -The arm, lines Practice and train your brain, your eyes and your arm to draw what you see using the four lines to communicate!show more