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This randomized #clinicaltrial demonstrated that adding low-dose intra-arterial alteplase after endovascular thrombectomy in acute ischemic #Stroke improved microvascular perfusion and functional outcomes compared with thrombectomy alone. Despite these findings, increased #mortality in the #alteplase group highlights the need for careful risk-benefit assessment when considering adjunctive pharmacologic strategies. 📖 Read the full article to learn more: 📹: Melanie Molina, MD MAS
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This randomized #clinicaltrial demonstrated that adding low-dose intra-arterial alteplase after endovascular thrombectomy in acute ischemic #Stroke improved microvascular perfusion and functional outcomes compared with thrombectomy alone. Despite these findings, increased #mortality in the #alteplase group highlights the need for careful risk-benefit assessment when considering adjunctive pharmacologic strategies. 📖 Read the full article to learn more: 📹: Melanie Molina, MD MAS

JAMA

16,592 views • 2 months ago

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