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A new HBO Max comedy series – a spin-off from "The Big Bang Theory" – features comic book store owner Stuart Bloom (Kevin Sussman) as an unlikely action hero trying to restore order to a disintegrating universe. Luke Burbank talks with Sussman, co-star Lauren Lapkus, and series creators Chuck...

45,718 次观看 • 2 个月前 •via X (Twitter)

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Your heart is Helical. The helical ventricular myocardial band (HVMB) theory, proposed by Francisco Torrent-Guasp in the 1960s and 1970s, offers a revolutionary perspective on the global, three-dimensional, functional architecture of the ventricular myocardium. This theory challenges the traditional view of the heart as a four-chambered pump with separate muscle layers, instead suggesting that the heart muscle fibers form a continuous, helical band extending from the pulmonary artery to the aorta. According to the HVMB theory, the ventricular myocardium consists of a single muscular band that wraps around both ventricles in a complex helical pattern. This band can be unwrapped or unfolded to reveal a rope-like structure with two main loops: a basal loop that surrounds the right and left ventricular cavities and an apical loop with descending and ascending segments that form a vortex at the apex. The theory proposes that this helical arrangement of muscle fibers is essential for the heart's efficient pumping function, allowing for the sequential contraction and relaxation of the myocardium. When Torrent-Guasp first introduced the HVMB theory in the 1960s and 1970s, it received little attention from the scientific community. The initial reaction was largely one of indifference, and the theory remained relatively obscure for several decades. It wasn't until the early 2000s, when Torrent-Guasp collaborated with researchers like Gerald Buckberg, that the HVMB theory gained more prominence and began to be more widely debated and investigated. Since then, the HVMB theory has been the subject of numerous studies, symposia, and discussions within the scientific community. Proponents of the theory argue that it provides a more comprehensive and accurate understanding of cardiac structure and function, offering new insights into the heart's mechanics and potential clinical implications. This is a very well done documentary called “The Helical Heart” that was released in 2005. It features an interview with Francisco Torrent-Guasp who came up with theory and lays it out in great detail. It completely blew my mind and changed the way I thought about the heart, especially when you consider it in concert with how the human biofield works.

Champagne Joshi

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Handmade Hero has spawned careers. It inspired Billy Basso who went to make ANIMAL WELL. It influenced Vjekoslav Krajačić to venture into unknown and start his business around File Pilot. , gingerBill, and many others attribute to this series a major influence on how they program. Handmade Hero is a publicly (!) available series of Casey Muratori streams where he programs a complex game project from scratch. He showcased how to use tools like the debugger, how to understand and inspect memory, and offered tons of invaluable info on how to develop and maintain a huge program. You can follow this course for ~30 (out of 700!) episodes and become a supercharged programmer. While your colleagues will be fighting over names for a variable, you will be confidently delivering features. When your friends will be making ridiculous statements about performance of the code, you will not rely on second-hand programming dogmas, but will be able to inspect it and address it. When for others, language SDK will be the lowest level they can operate on, you will confidently understand OS primitives and it will become your platform. Here's a conversation with Casey Muratori about Handmade Hero. There is a lot of unexpected turns here! Casey, it was an honour! Thank you, both for taking the time to come to the show and talk about the series, but also for making it in the first place! It was a monumental effort to keep it up every day for years!

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