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Borrow USDC in under 30s using solana:JUPyiwrYJFskUPiHa7hkeR8VUtAeFoSYbKedZNsDvCN as collateral. No credit check, no liquidation. 00:05 Launch Offerbook. 00:11 Browse available lending offers. 00:16 Set your collateral amount. 00:19 Review loan terms. 00:22 Confirm with 1 click. 00:25 Lend offer filled. 00:30 Monitor your active borrowing position. 00:33 USDC credited... show more

Jupiter Offerbook

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26,426 Aufrufe • vor 3 Monaten •via X (Twitter)

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USDC sitting idle? Put it to work. You don't need a protocol to set your APY for you. On Offerbook, you quote the rate. Create a lend offer in 30s ↓ 00:05 Launch Offerbook. 00:08 Initiate a lend offer. 00:09 Configure terms - You lend $USDC + they lock the asset. 00:12 Set the deal terms - LTV you accept + APY you charge. 00:17 Set duration. 00:18 Fill preferences. 00:22 Review and create offer. 00:25 Confirm with 1 click. 00:28 Lend offer created. 00:30 Funds enter escrow. 00:34 Monitor your active lending position. 00:38 Offer is live, awaiting fill. Just use Jupiter (Offerbook)

USDC sitting idle? Put it to work. You don't need a protocol to set your APY for you. On Offerbook, you quote the rate. Create a lend offer in 30s ↓ 00:05 Launch Offerbook. 00:08 Initiate a lend offer. 00:09 Configure terms - You lend $USDC + they lock the asset. 00:12 Set the deal terms - LTV you accept + APY you charge. 00:17 Set duration. 00:18 Fill preferences. 00:22 Review and create offer. 00:25 Confirm with 1 click. 00:28 Lend offer created. 00:30 Funds enter escrow. 00:34 Monitor your active lending position. 00:38 Offer is live, awaiting fill. Just use Jupiter (Offerbook)

Jupiter Offerbook

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New episode in the DeFi series is here! In this one, we will deep dive into Aave. 00:00:41 - What is Aave 00:03:20 - History of Aave 00:44:55 - ETHLend rebranded to Aave 00:05:33 - Aave launched v1 and it's features 00:09:20 - Aave v2 launch 00:12:40 - Aave v3 launch 00:20:30 - How Aave works and how interest rates are calculated 00:24:11 - Liquidations and Health factor 00:25:58 - Utility of AAVE token 00:27:51 - GHO stablecoin 00:30:20 - Aave Hands-on RT to show your love❤️

New episode in the DeFi series is here! In this one, we will deep dive into Aave. 00:00:41 - What is Aave 00:03:20 - History of Aave 00:44:55 - ETHLend rebranded to Aave 00:05:33 - Aave launched v1 and it's features 00:09:20 - Aave v2 launch 00:12:40 - Aave v3 launch 00:20:30 - How Aave works and how interest rates are calculated 00:24:11 - Liquidations and Health factor 00:25:58 - Utility of AAVE token 00:27:51 - GHO stablecoin 00:30:20 - Aave Hands-on RT to show your love❤️

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Open Tab Ep 3: Ashlee Vance on new media, getting close to Elon and showing audiences where the world is headed before it gets there. 00:00 "Elon might actually bankrupt me" 00:01:08 George Hotz joyride 00:07:09 Silicon Valley watering hole 00:09:00 They thought I was a woman 00:12:07 Life before and after the Elon biography 00:15:30 Monthly dinners with Elon 00:22:05 "95% accurate" 00:25:00 Elon said "I'm gonna destroy your life" 00:27:02 Kim Dotcom raid 00:27:30 Reconciling with Elon 00:29:49 Getting access to Neuralink 00:31:00 Bryan Johnson documentary 00:33:40 Funding movies 00:35:17 EVE Online 00:36:09 Hello World: Emmy nomination 00:37:18 Audience reach: Substack vs Bloomberg 00:38:39 PR people out of touch 00:40:13 65% of YouTube viewers watching on a TV 00:42:30 Ayahuasca on assignment 00:45:06 "I had the best job in media" 00:45:30 Started media company anyway

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Economy Annual Current Affairs - 100 Key Highlights for UPSC, SSC, Banking Exams by Dr.Mrunal Patel Timestamps: 00:00:00 - Introduction 00:00:24 - Headline Compilation 00:03:09 - Pillar 1: Money and Banking 00:03:31 - Deadline Enforcement 00:05:11 - Ease of Doing Business vs Public Safety 00:06:41 - Cheque Clearance Postponement 00:07:03 - UPI Updates 00:07:25 - Bitcoin Volatility and Trump 00:09:13 - Stablecoins and China Digital Yuan 00:10:19 - RBI Governors 00:11:02 - NPAs and Credit Card Issues 00:12:30 - Gold Loan Rules Relaxation 00:13:16 - IBC Code Amendments 00:13:39 - Pillar 2: Share Market 00:14:17 - Gold Price Surge and Smuggling 00:15:30 - Sovereign Gold Bonds Changes 00:16:13 - SEBI Leadership Shift 00:17:03 - Adani US Court Issues 00:18:08 - Tech Bubble Warnings 00:19:17 - Market Cap Examples 00:20:05 - Elon Musk Tesla Demands 00:20:55 - Over-Financialization Concerns 00:21:14 - F&O Trading Losses 00:22:21 - Corporate Nepotism at Reliance 00:23:09 - Pillar 1D: Insurance FDI Increase 00:23:51 - PM Jan Arogya Yojana Disputes 00:24:29 - Bima Sugam Portal 00:24:53 - Pension Incentives for Freshers 00:26:06 - Digital KYC Accessibility 00:27:12 - Pillar 2: Budget Taxation GST 00:27:38 Income tax relief 00:28:40 GST 2.0 00:30:43 Pan-Masala Cess 00:31:28 Finance Commission 00:31:48 Subsidies Revdi Culture 00:34:24 - Rupee Depreciation Reasons 00:34:59 - Trump Policies Impact 00:35:20 - Tariff Wars and Immigration 00:35:51 - Beautiful Bill and DOGE 00:36:12 - WTO Issues 00:36:56 - Democracy in Growth 00:37:21 - China Supply Chain Weaponization 00:37:51 - SCO and RIC Meetings 00:38:18 - Diplomacy No Permanent Friends 00:38:42 - FTA with UK 00:39:09 - Opportunities in Crisis 00:39:32 - EU Trade Deals 00:40:19 - Sanctions on Nayara 00:40:40 - Microsoft Reaction 00:41:02 - Digital Policy Need 00:41:26 - Pillar 4: Sectors of Economy 00:41:53 - PM Dhanya Krishi Yojana 00:42:14 - Makhana in Bihar 00:42:38 - No Major Farmer Sops 00:43:03 - Agriculture Budget 00:43:35 - Manufacturing PLI 00:43:57 - Startups and Criticism 00:44:31 - Startup Counterarguments 00:45:03 - Kolhapuri Chappal GI 00:45:52 - Four Labor Codes 00:46:16 - Engels Pause AI 00:46:42 - IT Job Losses 00:47:07 - Industrial Revolution Comparison 00:47:16 - PLFS Data 00:47:42 - GDP IMF Projection 00:48:01 - Growth vs Development 00:48:14 - Data Quality C Grade 00:48:33 - Methodology Changes 00:48:55 - Pillar 5: Infrastructure 00:49:22 - Nuclear Liability 00:50:06 - Mineral Partnerships 00:50:29 - US Exclusion 00:50:46 - Transport Pilot Rules 00:51:06 - Toll Systems 00:51:38 - Ethanol Blending 00:51:57 - Smart Cities Funding End 00:52:54 - Communication Infra 00:53:19 - Pillar 6: Census Delay 00:53:35 - Demographic Challenges 00:54:17 - Population Challenges 00:54:36 - Pension Age Debates 00:55:04 - Health Education Updates 00:55:28 - PM SHRI Scheme 00:55:40 - Open Book Exams 00:56:19 - IIT Issues 00:56:43 - Hindi Medium Initiative 00:57:05 - MGNREGA Extensions 00:57:48 - Poverty Definitions 00:58:27 - Inequality Gini 00:59:12 - HDI Rankings 00:59:43 - Other Indexes 00:59:48 - Win26 Series Announcement 01:00:10 - PCB15 Course Details 01:01:10 - Unacademy Offer 01:02:04 - Final Closing ✍🏻 Join Unacademy for UPSC Prelims + Mains Coaching:

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25,997 Aufrufe • vor 2 Monaten

It’s finally here. goes live in 2 hours. Trading opens today at 1:00 PM ET (17:00 UTC), available instantly on Axiom. The first USDC launchpad with cashback, creator fees, and referrals. If you want to share and earn, claim your referral code now: Follow Liquid.af for launch updates.

It’s finally here. goes live in 2 hours. Trading opens today at 1:00 PM ET (17:00 UTC), available instantly on Axiom. The first USDC launchpad with cashback, creator fees, and referrals. If you want to share and earn, claim your referral code now: Follow Liquid.af for launch updates.

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164,141 Aufrufe • vor 4 Monaten

NEW EPISODE: CHINA’S UNRESTRICTED WARFARE: General Michael Flynn at the Indo Pacific Summit | Ep 51 | Going Rogue with Lara Logan In this episode, General Michael Flynn, speaking at the Indo Pacific Summit in Washington D.C. on December 11, 2025, discusses the concept of “unrestricted warfare,” highlighting threats posed by China, Russia, and their allies through economic, political, and cyber means. He emphasizes China’s global influence, especially its control over major ports and rare earth minerals, and warns of internal U.S. vulnerabilities, including political subversion and educational infiltration. At the summit, Flynn urged cautious alliances, calling for honesty in diplomacy, stronger partnerships, and renewed patriotism. He encouraged Americans to engage locally and uphold foundational values to counter both external and internal threats to democracy and national security. Going Rogue with Lara Logan General Mike Flynn Unrestricted Warfare and Internal Threats (00:00:00) Historical Context of the Ukraine War (00:01:20) Strategic Negotiations and U.S. Interests (00:03:45) Gold and Silver Investment Advertisement (00:04:10) China’s Global Port Dominance (00:05:37) Diplomacy and Deception (00:07:30) Era of Fourth Generation Warfare (00:08:37) War as Human Nature and U.S. Military Engagements (00:09:56) Military-Industrial Complex and North Korean Dynasty (00:10:52) U.S.-Korea Alliance and Global Partnerships (00:11:56) Geography and Global Contest: Nationalism vs. Globalism (00:12:58) Shifting Alliances and Cultural Change (00:15:02) China’s Willingness to Sacrifice and Washington’s Farewell Address (00:17:30) Unrestricted Warfare and U.S. Vulnerabilities (00:19:43) Limits of U.S. Military Power (00:22:05) Conference Recap: China’s Global Reach (00:23:06) China’s Economic Rise and U.S. Policy (00:24:21) China’s Influence in the Western Hemisphere (00:25:27) Advice for Trump: Countering Chinese Influence (00:27:38) Dependence on China for Critical Materials (00:29:44) End of U.S. Geographic Security (00:30:19) Communist Infiltration and School Boards (00:30:37) Accountability in Leadership (00:33:29) Presidential Oath and Constitutional Preservation (00:35:27) Leftist Control of U.S. Cities (00:36:25) Foreign Policy and the Real Target (00:38:02) Call to Action and Hope for America (00:39:52)

NEW EPISODE: CHINA’S UNRESTRICTED WARFARE: General Michael Flynn at the Indo Pacific Summit | Ep 51 | Going Rogue with Lara Logan In this episode, General Michael Flynn, speaking at the Indo Pacific Summit in Washington D.C. on December 11, 2025, discusses the concept of “unrestricted warfare,” highlighting threats posed by China, Russia, and their allies through economic, political, and cyber means. He emphasizes China’s global influence, especially its control over major ports and rare earth minerals, and warns of internal U.S. vulnerabilities, including political subversion and educational infiltration. At the summit, Flynn urged cautious alliances, calling for honesty in diplomacy, stronger partnerships, and renewed patriotism. He encouraged Americans to engage locally and uphold foundational values to counter both external and internal threats to democracy and national security. Going Rogue with Lara Logan General Mike Flynn Unrestricted Warfare and Internal Threats (00:00:00) Historical Context of the Ukraine War (00:01:20) Strategic Negotiations and U.S. Interests (00:03:45) Gold and Silver Investment Advertisement (00:04:10) China’s Global Port Dominance (00:05:37) Diplomacy and Deception (00:07:30) Era of Fourth Generation Warfare (00:08:37) War as Human Nature and U.S. Military Engagements (00:09:56) Military-Industrial Complex and North Korean Dynasty (00:10:52) U.S.-Korea Alliance and Global Partnerships (00:11:56) Geography and Global Contest: Nationalism vs. Globalism (00:12:58) Shifting Alliances and Cultural Change (00:15:02) China’s Willingness to Sacrifice and Washington’s Farewell Address (00:17:30) Unrestricted Warfare and U.S. Vulnerabilities (00:19:43) Limits of U.S. Military Power (00:22:05) Conference Recap: China’s Global Reach (00:23:06) China’s Economic Rise and U.S. Policy (00:24:21) China’s Influence in the Western Hemisphere (00:25:27) Advice for Trump: Countering Chinese Influence (00:27:38) Dependence on China for Critical Materials (00:29:44) End of U.S. Geographic Security (00:30:19) Communist Infiltration and School Boards (00:30:37) Accountability in Leadership (00:33:29) Presidential Oath and Constitutional Preservation (00:35:27) Leftist Control of U.S. Cities (00:36:25) Foreign Policy and the Real Target (00:38:02) Call to Action and Hope for America (00:39:52)

Lara Logan

16,229 Aufrufe • vor 7 Monaten

Everyone knows alon But @pumpdotfun actually has three co-founders We hosted Sapijiju for his first-ever conversation about $PUMP Timestamps 0:00 Intro & Noah's Crypto Journey 7:15 Learning from Failure to Product Market Fit 11:20 Crypto's Lack of Innovation 16:30 Current Creator Models are Broken 18:00 Pump's Content Vision 23:00 Pump as a Product First Operation 25:00 Growing the Pie for Streaming 29:00 Innovating on Content Distribution 34:00 Letting Content Grow Organically 37:40 +$1.5B worth of SOL is locked in Pump Liquidity Pools 40:20 Creating a Global Impact with Pump 42:20 What could Pump do with its Warchest? 47:00 The Pump Buybacks 51:00 Why People use Pump 54:00 The Culture Shift of Crypto 57:00 Traditional models no Longer Work 59:00 The Cycle of Human Nature

Everyone knows alon But @pumpdotfun actually has three co-founders We hosted Sapijiju for his first-ever conversation about $PUMP Timestamps 0:00 Intro & Noah's Crypto Journey 7:15 Learning from Failure to Product Market Fit 11:20 Crypto's Lack of Innovation 16:30 Current Creator Models are Broken 18:00 Pump's Content Vision 23:00 Pump as a Product First Operation 25:00 Growing the Pie for Streaming 29:00 Innovating on Content Distribution 34:00 Letting Content Grow Organically 37:40 +$1.5B worth of SOL is locked in Pump Liquidity Pools 40:20 Creating a Global Impact with Pump 42:20 What could Pump do with its Warchest? 47:00 The Pump Buybacks 51:00 Why People use Pump 54:00 The Culture Shift of Crypto 57:00 Traditional models no Longer Work 59:00 The Cycle of Human Nature

Delphi Digital

257,968 Aufrufe • vor 10 Monaten

Ivan Raiklin NAMES The Deep State, J6, & Stolen Election Conspirators! ⏲️ TIME STAMPS ⏲️ 0:00 : Preview… 11:00 : Show begins!🔥 - Quick Announcements 13:00 : Who is Ivan Raiklin? 15:00 : Mark Zuckerberg admitted to gen0c!de & stealing 2020 elections 17:00 : Who is the Deep State? 23:00 : Working at the Ukraine crisis team in 2014 29:30 : Hunter Biden 41:00 : Every Presidential Findings leads to CIA covert action 47:00 : The Deep State went after General Flynn & coerced him into a guilty plea 51:00 : What prompted Ivan to expose the Deep State? 56:00 : Exposing Catherine Semen & Josh Pitc0ck 1:01:00 : Sponsor - Rumble Premium / We’ll stream on Rumble & Twitch exclusively from next week 1:04:00 : Summary of the show & Deep State connection with the CIA 1:09:00 : Viral Video of Ivan - Calling Deep State by name 1:19:00 : C0v!D va**!ne = DNA mutilation / 80,000+ soldiers left the military because of the mandate 1:27:00 : Exposing Jim Baker of FBI & Mike Pence 1:31:00 : TDS - Trump Derangement Syndrome 1:33:00 : The Speaker of The House is the most powerful person on the planet 1:37:00 : Why are the JFK files still not declassified? 1:40:00 : How the Deep State manipulates the politicians 1:42:00 : Thomas Massie 1:44:00 : How is Ivan still alive? 1:48:30 : Sponsor - BeNaked (Guest gets naked for the ad💀😂) 1:51:30 : January 6th riots & never seen before details 2:07:00 : Black privilege 2:08:00 : Ivan goes after the J6 coverup committee 2:14:00 : Jack Smith is an idiot 2:16:00 : How they violated the constitution & stole the 2020 elections 2:34:00 : LinkedIn kicked out Ivan for running as a Republican 2:37:00 : 12th Amendment - The house will decide who the president is 2:54:00 : Did Mike Pence knew about all of this? 2:56:00 : Mike Pence planned a trip to Isr@el starting January 6th 3:05:30 : The only way Nancy Pelosi can stop the guaranteed re-election 3:08:00 : Sponsor - 1775 Coffee 3:10:00 : Mike Pence role on January 6th 3:19:00 : Myron gets his mind blown 3:22:30 : Mike Pence’s letter on Jan 6 3:27:00 : Trump is bringing in all the snakes who didn’t support him before 3:32:00 : How the January 6th Feds ressurection took place 3:39:30 : Who is Yogananda Pittman

Ivan Raiklin NAMES The Deep State, J6, & Stolen Election Conspirators! ⏲️ TIME STAMPS ⏲️ 0:00 : Preview… 11:00 : Show begins!🔥 - Quick Announcements 13:00 : Who is Ivan Raiklin? 15:00 : Mark Zuckerberg admitted to gen0c!de & stealing 2020 elections 17:00 : Who is the Deep State? 23:00 : Working at the Ukraine crisis team in 2014 29:30 : Hunter Biden 41:00 : Every Presidential Findings leads to CIA covert action 47:00 : The Deep State went after General Flynn & coerced him into a guilty plea 51:00 : What prompted Ivan to expose the Deep State? 56:00 : Exposing Catherine Semen & Josh Pitc0ck 1:01:00 : Sponsor - Rumble Premium / We’ll stream on Rumble & Twitch exclusively from next week 1:04:00 : Summary of the show & Deep State connection with the CIA 1:09:00 : Viral Video of Ivan - Calling Deep State by name 1:19:00 : C0v!D va**!ne = DNA mutilation / 80,000+ soldiers left the military because of the mandate 1:27:00 : Exposing Jim Baker of FBI & Mike Pence 1:31:00 : TDS - Trump Derangement Syndrome 1:33:00 : The Speaker of The House is the most powerful person on the planet 1:37:00 : Why are the JFK files still not declassified? 1:40:00 : How the Deep State manipulates the politicians 1:42:00 : Thomas Massie 1:44:00 : How is Ivan still alive? 1:48:30 : Sponsor - BeNaked (Guest gets naked for the ad💀😂) 1:51:30 : January 6th riots & never seen before details 2:07:00 : Black privilege 2:08:00 : Ivan goes after the J6 coverup committee 2:14:00 : Jack Smith is an idiot 2:16:00 : How they violated the constitution & stole the 2020 elections 2:34:00 : LinkedIn kicked out Ivan for running as a Republican 2:37:00 : 12th Amendment - The house will decide who the president is 2:54:00 : Did Mike Pence knew about all of this? 2:56:00 : Mike Pence planned a trip to Isr@el starting January 6th 3:05:30 : The only way Nancy Pelosi can stop the guaranteed re-election 3:08:00 : Sponsor - 1775 Coffee 3:10:00 : Mike Pence role on January 6th 3:19:00 : Myron gets his mind blown 3:22:30 : Mike Pence’s letter on Jan 6 3:27:00 : Trump is bringing in all the snakes who didn’t support him before 3:32:00 : How the January 6th Feds ressurection took place 3:39:30 : Who is Yogananda Pittman

Myron Gaines

110,419 Aufrufe • vor 1 Jahr

Ludvig Åberg breaks down his strategy for every hole at Augusta National in TGJ Podcast #207: 00:01:11 But first, some LEGO talk. 00:10:52 No. 1: The hardest pin on the course. 00:14:42 No. 2: Left is dead, so you have to love the bunker. 00:18:36 No. 3: "I've got trust issues with banking it into the hill." 00:22:49 No. 4: The most visually deceptive hole at Augusta. 00:25:02 No. 5: "It's long and has one of the hardest greens." 00:27:07 No. 6: Hit it high to fit the swirling wind 00:29:46 No. 7: The simplest hole, but only if you hit the fairway. 00:31:22 No. 8: More uphill than you think. 00:33:31 No. 9: "It sets up for a low cut or low skank." 00:39:04 No. 10: The left side of the fairway is the place to be. 00:41:56 No. 11: "If I could ever take back one shot, it'd be here." 00:43:50 No. 12: Limit the external factors as much as you can. 00:48:23 No. 13: Ludvig is a reformed doubter of the pull of Rae's Creek. 00:52:15 No. 14: It's birdie or bust. 00:54:20 No. 15: The layup debate in the caddie room is real. 00:57:56 No. 16: "The highlights make the left pin look automatic. It’s not." 00:59:26 No. 17: Rae's Creek has some mythical pull up here too. 01:01:15 No. 18: Rory's winning putt was harder than you think. 01:07:57 The last book Ludvig read is exactly what you'd expect.

Ludvig Åberg breaks down his strategy for every hole at Augusta National in TGJ Podcast #207: 00:01:11 But first, some LEGO talk. 00:10:52 No. 1: The hardest pin on the course. 00:14:42 No. 2: Left is dead, so you have to love the bunker. 00:18:36 No. 3: "I've got trust issues with banking it into the hill." 00:22:49 No. 4: The most visually deceptive hole at Augusta. 00:25:02 No. 5: "It's long and has one of the hardest greens." 00:27:07 No. 6: Hit it high to fit the swirling wind 00:29:46 No. 7: The simplest hole, but only if you hit the fairway. 00:31:22 No. 8: More uphill than you think. 00:33:31 No. 9: "It sets up for a low cut or low skank." 00:39:04 No. 10: The left side of the fairway is the place to be. 00:41:56 No. 11: "If I could ever take back one shot, it'd be here." 00:43:50 No. 12: Limit the external factors as much as you can. 00:48:23 No. 13: Ludvig is a reformed doubter of the pull of Rae's Creek. 00:52:15 No. 14: It's birdie or bust. 00:54:20 No. 15: The layup debate in the caddie room is real. 00:57:56 No. 16: "The highlights make the left pin look automatic. It’s not." 00:59:26 No. 17: Rae's Creek has some mythical pull up here too. 01:01:15 No. 18: Rory's winning putt was harder than you think. 01:07:57 The last book Ludvig read is exactly what you'd expect.

The Golfer's Journal

157,909 Aufrufe • vor 3 Monaten

We don't know what most microbial genes do. Can genomic language models help? there's only one way to find out! this is a 1 hour and 42 minute interview with an MIT professor (the famous Yunha Hwang) chatting about these questions, her work in solving them at Tatta Bio, and more. zoomer captions are back too Links in reply! Timestamps: 00:00:00 - Clips + sponsor roll from the wonderful LatchBio 00:02:07 – Introduction 00:02:23 – Why do microbial genomes matter 00:04:07 – Deep learning acceptance in metagenomics 00:05:25 – The case for genomic “context” over sequence matching 00:06:43 – OMG: the only ML-ready metagenomic dataset 00:09:27 – gLM2: A multimodal genomic language model 00:11:06 – What do you do with the output of genomic language models? 00:17:41 – How will OMG evolve? 00:20:26 – Why train on only microbial genomes, as opposed to all genomes? 00:22:58 – Do we need more sequences or more annotations? 00:23:54 – Is there a conserved microbial genome ‘language’? 00:28:11 – What non-obvious things can this genomic language model tell you? 00:33:08 – Semantic deduplication and evaluation 00:37:33 – How does benchmarking work for these types of models? 00:41:31 – Gaia: A genomic search engine 00:44:18 – Even ‘well-studied’ genomes are mostly unannotated 00:50:51 – Using agents on Gaia 00:54:53 – Will genomic language models reshape the tree of life? 00:59:18 – Current limitations of genomic language models 01:08:54 – Directed evolution as training data 01:12:35 – What is Tatta Bio? 01:19:02 – Building Google for genomic sequences (SeqHub) 01:25:46 – How to create communities around scientific OSS 01:29:06 – What’s the purpose in the centralization of the software? 01:35:37 – How will the way science is done change in 10 years?

We don't know what most microbial genes do. Can genomic language models help? there's only one way to find out! this is a 1 hour and 42 minute interview with an MIT professor (the famous Yunha Hwang) chatting about these questions, her work in solving them at Tatta Bio, and more. zoomer captions are back too Links in reply! Timestamps: 00:00:00 - Clips + sponsor roll from the wonderful LatchBio 00:02:07 – Introduction 00:02:23 – Why do microbial genomes matter 00:04:07 – Deep learning acceptance in metagenomics 00:05:25 – The case for genomic “context” over sequence matching 00:06:43 – OMG: the only ML-ready metagenomic dataset 00:09:27 – gLM2: A multimodal genomic language model 00:11:06 – What do you do with the output of genomic language models? 00:17:41 – How will OMG evolve? 00:20:26 – Why train on only microbial genomes, as opposed to all genomes? 00:22:58 – Do we need more sequences or more annotations? 00:23:54 – Is there a conserved microbial genome ‘language’? 00:28:11 – What non-obvious things can this genomic language model tell you? 00:33:08 – Semantic deduplication and evaluation 00:37:33 – How does benchmarking work for these types of models? 00:41:31 – Gaia: A genomic search engine 00:44:18 – Even ‘well-studied’ genomes are mostly unannotated 00:50:51 – Using agents on Gaia 00:54:53 – Will genomic language models reshape the tree of life? 00:59:18 – Current limitations of genomic language models 01:08:54 – Directed evolution as training data 01:12:35 – What is Tatta Bio? 01:19:02 – Building Google for genomic sequences (SeqHub) 01:25:46 – How to create communities around scientific OSS 01:29:06 – What’s the purpose in the centralization of the software? 01:35:37 – How will the way science is done change in 10 years?

owl

44,279 Aufrufe • vor 7 Monaten

"You just can't build a slow, expensive blockchain anymore." Solana founder toly 🇺🇸 built a $47 billion network from an idea he couldn't sleep on. Two coffees and a beer at Cafe du Soleil in 2017, and he was up until 4 a.m., figuring out how to use proof of work to measure time. His parents escaped the USSR in the 90s with $50 to their name and landed in Chicago in their 40s. His mom was a pianist. His dad was a civil engineer who took blue-collar roofing jobs while getting his electrician certificates. His son did the circuit analysis homework for him. That 4 a.m. idea became proof of history, the core mechanism behind Solana. In this episode: 00:00:00 Trailer 00:01:06 Intro 00:01:17 Growing up in the Soviet Union 00:04:02 Immigrating to the United States 00:07:34 Career dreams and studying computer science 00:09:47 First startup and early lessons 00:11:19 13 years at Qualcomm 00:22:32 Meeting Raj and founding Solana 00:26:44 Fundraising and early investors 00:28:41 Surviving the FTX collapse 00:40:19 Solana's mission and impact 00:43:54 Using AI to run side projects 00:49:39 Hardest decisions as a leader 00:52:51 Outlook on crypto and Solana's future 00:59:22 Twitter, being public, and politics 01:05:52 Beliefs on human nature and life philosophy 01:09:34 Outro Full episode:

"You just can't build a slow, expensive blockchain anymore." Solana founder toly 🇺🇸 built a $47 billion network from an idea he couldn't sleep on. Two coffees and a beer at Cafe du Soleil in 2017, and he was up until 4 a.m., figuring out how to use proof of work to measure time. His parents escaped the USSR in the 90s with $50 to their name and landed in Chicago in their 40s. His mom was a pianist. His dad was a civil engineer who took blue-collar roofing jobs while getting his electrician certificates. His son did the circuit analysis homework for him. That 4 a.m. idea became proof of history, the core mechanism behind Solana. In this episode: 00:00:00 Trailer 00:01:06 Intro 00:01:17 Growing up in the Soviet Union 00:04:02 Immigrating to the United States 00:07:34 Career dreams and studying computer science 00:09:47 First startup and early lessons 00:11:19 13 years at Qualcomm 00:22:32 Meeting Raj and founding Solana 00:26:44 Fundraising and early investors 00:28:41 Surviving the FTX collapse 00:40:19 Solana's mission and impact 00:43:54 Using AI to run side projects 00:49:39 Hardest decisions as a leader 00:52:51 Outlook on crypto and Solana's future 00:59:22 Twitter, being public, and politics 01:05:52 Beliefs on human nature and life philosophy 01:09:34 Outro Full episode:

luba yudasina

256,492 Aufrufe • vor 22 Tagen

🚨New Episode: Please welcome Shiloe Bear to the Fort! As the founder of Creek Development, Shiloe has completed 63 commercial redevelopment projects and 5 land entitlement plays in the San Francisco Bay Area. Leveraging her deep construction expertise, she challenges project assumptions and incorporates impactful design to achieve remarkable outcomes for her clients and investors. We discuss: - Building Creek as an outsourced developer - Converting industrial buildings into biotech lab space - A deep dive into the Bay Area RE market - Why design is such an important aspect of development 00:00:00 - Intro 00:01:11 - Shiloe’s upbringing and journey to doing development in the Bay Area 00:08:25 - What are the projects you work on the most? 00:11:01 - Why is there such a demand for outsourced development? 00:11:47 - What makes your firm different? 00:16:50 - Minimum Viable Projects 00:21:47 - How early in a project do you need to be brought in? 00:25:14 - What are some obvious parts of a project where you can save money? 00:27:30 - How would you describe the Bay Area market right now? 00:33:35 - Office to Residential 00:37:46 - What’s the environment like for Oakland? 00:42:31 - How Shiloe is planning to pivot her business into doing their own developments 00:47:51 - How important are the relationships you’ve developed in The Bay over the past 10 years? 00:53:06 - The BioTech market and development strategy 01:00:55 - Why design matters 01:08:27 - How far out are labs looking for space? 01:09:46 - Lenders, Leases, and hold periods 01:12:36 - Why did this become your niche? 01:14:13 - Shiloe’s bird-watching skills & long-distance running

🚨New Episode: Please welcome Shiloe Bear to the Fort! As the founder of Creek Development, Shiloe has completed 63 commercial redevelopment projects and 5 land entitlement plays in the San Francisco Bay Area. Leveraging her deep construction expertise, she challenges project assumptions and incorporates impactful design to achieve remarkable outcomes for her clients and investors. We discuss: - Building Creek as an outsourced developer - Converting industrial buildings into biotech lab space - A deep dive into the Bay Area RE market - Why design is such an important aspect of development 00:00:00 - Intro 00:01:11 - Shiloe’s upbringing and journey to doing development in the Bay Area 00:08:25 - What are the projects you work on the most? 00:11:01 - Why is there such a demand for outsourced development? 00:11:47 - What makes your firm different? 00:16:50 - Minimum Viable Projects 00:21:47 - How early in a project do you need to be brought in? 00:25:14 - What are some obvious parts of a project where you can save money? 00:27:30 - How would you describe the Bay Area market right now? 00:33:35 - Office to Residential 00:37:46 - What’s the environment like for Oakland? 00:42:31 - How Shiloe is planning to pivot her business into doing their own developments 00:47:51 - How important are the relationships you’ve developed in The Bay over the past 10 years? 00:53:06 - The BioTech market and development strategy 01:00:55 - Why design matters 01:08:27 - How far out are labs looking for space? 01:09:46 - Lenders, Leases, and hold periods 01:12:36 - Why did this become your niche? 01:14:13 - Shiloe’s bird-watching skills & long-distance running

Chris Powers

64,474 Aufrufe • vor 2 Jahren