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Brand-new research (PMID: 42102814) has uncovered a bizarre link between a compound found in aged garlic and longevity. 🧄 It's called: S1PC. Remarkably, it causes fat cells to release tiny vesicles carrying an enzyme that travels to the brain, boosting levels of the energy molecule NAD in just minutes....

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Dr. Daniel Monti just revealed a potentially massive breakthrough in Parkinson’s disease treatment. And it’s much simpler than you think. He just published his third study on a molecule called N-acetylcysteine, or “NAC for short.” “This is a powerful antioxidant.” “It actually protects the liver.” “We know that it does a lot of different things, but the important thing for us is that it’s a precursor to something called glutathione.” “Glutathione protects the brain when there’s damage or oxidative stress and we lose it as we age.” “And when we get sick, we lose it even more.” “So we want to have a way to efficiently increase glutathione in the brain, particularly when we have a neurodegenerative disorder such as Parkinson’s disease.” “We hypothesized early on that giving infused N-acetylcysteine would increase glutathione and actually have a positive impact on Parkinson’s disease.” “We’ve published three studies on this and we look at brain scans in all of them.” “And what we’ve seen is that the N-acetylcysteine increases the efficiency of dopamine in the brain, which is the neurotransmitter or chemical that gets lost in Parkinson’s disease and causes all of those symptoms.” “Our most recent study shows that it improves the way the brain connects to itself or talks to itself the functional connectivity in the brain.” “To be in the study, you couldn’t have changes in your Parkinson's medications for a period of time.” “In both the control group and in the NAC group, people were on their Parkinson’s medications, but if they got the NAC, they did better.” “Their brain came alive in a way that wasn’t happening before.”

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Saunas Can Reduce Food Intake?! – New Insights from Nature 🔥🧠 (2 min science breakdown clip) It’s been observed that heat exposure reduces food intake both in humans and animals, leading some to suggest heat stress may be a weight management tool. And new science is beginning to unpack how heat may suppress appetite. Get ready for a steam burst of jargon, then I’ll simplify: A 2024 paper published in nature (PMID: 38538787) found that heat 🔥activates specialized cells that line the fluid-filled spaces in the brain called, “tanycytes.” 🎯These tanycytes are optimally placed to communicate external signals to regions of the brain, in particular the hypothalamus, that control things like metabolism and food intake. 🔥This study found that heat stress in a mouse model at 40°C for 1 hour increased activity in a temperature sensing brain region, the “pontine parabrachial nucleus (PBN)” 👉which signals to tanycytes and causes them to 👉produce a brain chemical VEGFA, which in turn 👉 signals to the hypothalamus to change the activity of dopamine and AGRP neurons and leads to reduce food intake. (Please see clip for a visual explanation) 🚨High-Level Takeaway: The researchers discovered a causal mechanism for the effects of heat on reducing food intake, and aligns with data in humans that heat can reduce food intake. More details about sauna in today’s #StayCurious Newsletter (linked in first reply), including discussion of heart health, brain health, longevity, and with a healthy shoutout to Dr. Rhonda Patrick (who I suspect might be interested in this Tanycytes Mechanism, if it's not already on her radar) Some folks interesting in Sauna and/or Neuroscience Mechanisms: Dan Go Gary Brecka Andrew D. Huberman, Ph.D. (Wonder what will be in #Protocols: An Operating Manual for the Human Body on Saunas?📖🐰🕳️?) Rob Mohr Robb Wolf Nicholas Fabiano, MD Amy Berger Meat Head Chris Palmer, MD #sauna #neuroscience #longevity #healthspan #appetite #metabolichealth

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🚨🚨🚨 Dutch Cancer Researcher and Erasmus Medical Centre Assc Prof Maarten Fornerod discusses DNA contamination in COVID Vaccines. ---------------------------- ...for last 35 years or so I've been working uh in the areas of molecular biology, gene expression, biology, cancer biology and recently in the last years, maybe last 10 years in the context of big data and computational biology... ...when we use genetic vaccines what we do essentially is we're making a complex intervention in a very complex system. It's impossible to predict what happens if you combine these two complex systems, and you get unpredictable effects. .. And the only way to go about this is to do genotoxic research, when you want to introduce a genetic medicine into a human being and that genetotic research has to be independent, it has to be double blind, has to be long lasting. AND ALL THESE HAVE NOT BEEN DONE WITH THE GENETIC CORONA VACCINES! if there's a vaccine, there's a little bit of DNA in there upon injection that is very, very rapidly degraded by the human body. However if it's protected and in a lipid nanoarticle it can very efficiently be transduced in the cell... I've been doing this this many, many times. This is called lipofection and it's a very efficient way to introduce DNA into a cell. ...Many people think that this is not possible. But I've been working in nuclear transport for many years, I think more than 10 years. So I've been exposed to a lot of molecular cell biology of nuclear cytoplasmic transport. And it's clear that the DNA can enter the nucleus. Now to make things worse, the mRNA vaccine doesn't stay in the arm but it's detected in , in all different organs including the reproductive system. And so partly this is based on animal models, of course we know from Michael Morz that he has detected uh the spike protein in brain, in the heart and it's for sure it's detected in the blood and even in breast milk. ..So there's NO DOUBT that this mRNA vaccine spreads widely in the human body. ..Now from a genetic point of view, there are possible consequences uh of this and the consequences could be a 1. long term disruption of cellular processes that could lead to disease. 2. there's a risk of insertional mutageenesis in somatic cells that can lead to cancer. 3. the insertion mutogenesis takes place in a germ cell which would be a hereditary burden uh on the human population. 4. And you could also think that these um DNAs, could transfect the microbiome and it could possibly lead to bacterial resistance. So these are all possible..the consequences of these genetic vaccines in my view, the shortcomings in this rollout of these vaccines were there was no genotoxic research performed at all. There was no safety studies, on carcinogenic potential of these vaccines. My personal opinion is that it's now not a question of whether, it will integrate in recipient's DNA, but how often it occurs... It's just a numbers game. If you do this in many cells, many persons it will no doubt integrate in cells in human recipients. So the question does it affect the human genome? I would say it probably, I think it most certainly does. And you see Kevin McKernan here and he represented ah a preliminary data where he detected a possible Pfizer DNA in colon cancer biopsy one year after vaccination.

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