🚨 BREAKING: Scientists just found specific gut bacteria that can trigger MS-like disease ... using identical twins as proof. One twin had MS, the other didn’t. They had the same DNA and the same upbringing. But, totally different gut bacteria. What they discovered is wild. Thread 🧵

Can we TREAT MS by fixing the gut? Researchers are trying. ✅ Fecal transplants (FMT) — replacing a patient's gut bacteria with a healthy donor's — showed real improvements in spasticity, motor skills & GI symptoms in a 2025 trial. ✅ Registered clinical trial are running RIGHT NOW … or planned Not theoretical. Happening now.

How do gut bacteria trigger BRAIN disease? 4 ways scientists have now identified: 1️⃣ Molecular mimicry — bacteria look like your nerves coating, the immune system attacks both 2️⃣ Leaky gut → leaky brain barrier → immune cells flood your CNS 3️⃣ Immune imbalance — wrong bacteria tip your defences toward autoimmunity 4️⃣ Loss of SCFAs — protective molecules vanish, Inflammation takes over

They pinpointed TWO specific bacteria as the likely culprits. Both from the Lachnospiraceae family: 🦠 Eisenbergiella tayi 🦠 Lachnoclostridium sp. Bonus finding that stopped researchers cold: Female mice were 3× MORE vulnerable to these bacteria. Women are also 3× more likely to get MS in real life. 🤯 The sex difference in MS may run through the GUT.

If this thread was useful: ♻️ Repost tweet 1 — someone you know may need this ❤️ Like so, the algorithm spreads the science 🔔 Follow for more deep dives — real papers, no hype I read the peer-reviewed studies so you don't have to. Full study screenshots have been added👇 Message me for links.

Let's be honest about what we DON'T know yet. ❌ No probiotic is a proven MS treatment ❌ FMT has no large clinical trial confirmation yet ❌ We can't say one bacterium causes MS in all people ❌ Dysbiosis may be a cause AND/OR consequence The accurate statement as of 2026: "Specific gut bacteria can likely contribute to triggering MS in genetically susceptible people." That's huge. But it's not a cure. Not yet.

Here's what they did. They took gut bacteria from the small intestine of MS twins... ...and transferred them into specially bred mice that are prone to develop MS-like brain disease. The mice given MS-human bacteria got sick FAR more often. The ones given healthy-twin bacteria? Much less. 🐭

This isn't one study in isolation. 📌 2022: The largest MS microbiome study ever (Cell journal) — 1,100+ patients. Same pattern. 📌 2025: Yale found that MS patients have abnormal immune responses to gut bacteria — possibly BEFORE diagnosis. 📌 2021: Kids with MS who had more protective gut bacteria had up to 54% LOWER relapse risk. This signal is everywhere.

MS affects 2.8 million people worldwide. No cure exists. And for decades, nobody could explain why it STARTS. Scientists knew MS patients had different gut bacteria. But was that the CAUSE — or just a side effect? A 2025 study just answered that question. 👇

In 2025, researchers at LMU Munich published a landmark study in PNAS — one of the most prestigious science journals. They studied 81 pairs of IDENTICAL TWINS. One twin had MS. One didn't. Same DNA. Same childhood. But completely different gut bacteria. That's how you find the real signal. 🔬

@morgfair As someone living with MS, thank you for not giving up on research and a potential cure.

Thank you so much for saying that ♥️ As someone actually living with MS, your words mean a lot. My background is mostly cancer, Alzheimer's, Parkinson's, metabolism and aging. I understand MS .. but I need to read twice and make sure before I post anything about MS. I want it to mean something for the public. If there is something they can do by changing lifestyle, that is the first focus. Then come interventions. I am always reading about MS and ALS and others and will post as much as possible. This study with the identical twins hit me hard too ... same DNA, same life, but completely different gut bacteria deciding who gets the disease. It really drives home how personal and individual this all is. We’re still early on turning this into treatments (FMT trials are happening), but research like this gives real hope. Sending you strength and gratitude for being in the fight. Keep going 💪🙏

@JacDalAM @morgfair Isnt this similar for PD?

@JacDalAM @morgfair Yes. This is exactly what I researched when I was doing my post doc. I was looking for leaky gut and gut links for aging, PD and AD. I am right now doing meta analysis looking into PD and microbiome. This is a small thread I did in April

@JacDalAM @morgfair Thank you for working on this, clearly you care

@JacDalAM @morgfair Thank you. 😊 Yes I am passionate about this on AD and PD angles. I want to get solid information out to people. There are so many changes people can do to reduce disease progression and also get their medication to respond better.

C’est comme ça pour le diabète, l’alzheimer, et plusieurs autres maladies.

100% correct. I am right now doing meta analysis on PD and microbiome. Made a small thread earlier too. Also looking into how treatment options can change with changes to the gut microbiome.

Cutting out most carbs can change both of those in the gut biome. I’ve seen many with MS change their diets and say it hasn’t progressed. Most of the changes always involve cutting out most carbs and sugars that feed those specific bacteria.

Exactly. This is the same route for PD too. And cancer and AD as studies emerge.

Pretty cool. Getting patients to make those changes is the hard part.

You are bringing up an important point. It's so easy to advise ... eat well, exercise, sleep. But with everyday issues, work stress, and financial worries. socio-economic factors, family cultural beliefs, addictions, abuse, and intellectual aspects all contribute to making everybody's situation unique. I have stopped judging people for not following simple instructions. It is more complicated than that. We need to start looking at all of this for proper care.

What advice would you give an MS patient?

Really good question. MS isn’t just one disease ... it shows up very differently in each person, so a proper diagnosis and personalized plan with a neurologist is the most important first step. What the science is increasingly showing is how much the gut microbiome matters ... not just for overall health, but even how well medications work. Eating fermented foods + plenty of fiber seems to help lower inflammation (which is a root driver in many chronic conditions). There are also several promising new clinical trials and strategies right now aimed at slowing progression and improving symptoms. I’m actually planning to put together a bigger overview soon on the current landscape ... what’s working in trials, microbiome research, and practical things that may help reduce symptoms and progression. But please ... always run anything new by your own doctor first.

Dismissing a software engineer ignores the necessity of data modeling in complex lipidology. The lead author partnered with a board-certified lipidologist and a medical doctor with a doctorate of philosophy for clinical oversight. Scientific rigor dictates validity, not titles.

Never dismissed him. But there's a conflict of interest. We always disclose when we publish, which they did not.

Criticizing the lack of dietary macronutrient logs misses the biological mechanism. If circulating beta-hydroxybutyrate is elevated, the subject is definitively in ketosis. Direct biomarker measurement of ketone bodies completely supersedes subjective food questionnaires.

I think this is relevant for the keto paper that's been reacted.

The magic headline: "BREAKING: Scientists......" and most people will believe it. Furtunatly they are getting fewer and fewer.

MS is not one disease. Many root causes and many pathologies. Not understanding that is a major issue. This is a lot of misinformation. Weirdly I just blocked someone who said the same thing word to word. MS is NOT caused by parasites and please disregard this person.

MS is not one disease. It has many root causes and several pathologies. The parasite ivermectin sellers are spreading lies and misinforming patients and loved ones. Please do not listen to these lies. I have researched in lab for 20+ years and I have personally worked on ivermectin. This does not work. Please disregard this person's comments.

PARASITES are the cause of MS.

MS is not one disease. There are many root causes. The study actually found specific gut bacteria (not parasites) in the MS twin. The identical-twin data is in the thread if you’re curious. I have actually done research in ivermectin. Does not work.

Have you heard about PARASITES being found in brain of MS patients?🤔

21+ years doing research in labs, dozens of coneferences and tens and thousands of papers and scientists I have met ... No, parasites in the brain. Conspiracy theorists like to talk about it and the gullible who have not read scientific articles and listen to people with misinformation do. I repeat ... i have worked on ivermectin. I know more than most people. The whole ivermectin talk is a hoax and really hurts sick people. This study found specific gut bacteria in the MS twin that triggered stronger inflammation when transferred to mice. The identical-twin data is in the pinned thread if you’re curious. End of conversation ... one more mention of parasite and I will block.

I never said anything about IVERMECTIN. I said MS is caused by PARASITES. And there’s scientists who will totally disagree with you. I can always tell when I hit a nerve. PS - I don’t follow you. So block me.✊🏽