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Breakthrough Update: Today, Vertex announced that they are beginning their Phase 3, or pivotal trial for VX-880, a stem cell-derived islet therapy. A pivotal trial gathers the data required for an FDA submission. This therapy is for people with type 1 diabetes (T1D) and hypoglycemia unawareness and severe hypoglycemic... episodes. This is a HUGE first for the #T1D community as it is the first time a scalable cure for some people with T1D is entering this phase. Breakthrough T1D and the T1D Fund are incredibly proud to have supported this work in cell therapies—a top priority for our organization. We want to congratulate our partners at Vertex and thank all the patients who have participated in clinical trials. Your courage and commitment are inspiring. Learn more here:show more

Breakthrough T1D

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42,413 views • 1 year ago •via X (Twitter)

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9 Comments

LinnBee🌸1 year ago

Nice. Does this need any immuno suppressants? Stem cell is a very exciting field.

Michael Moraal1 year ago

@amsterdamumc @DiabetesNL ik hoop dat VX-264 ook naar Nederland komt na die FDA submission 🙏

john callinan1 year ago

@isletbiologylab For the first time a cure in five years may actually be accurate.

L A U R A ... ♥🌼1 year ago

This would be so much more heartwarming if it was for ALL T1, not just some. A great effort so far, but can it really be classed as a T1 cure if not all T1s can be cured?

BioBoost1 year ago

Could targeting insulin-degrading enzyme (IDE) hold the key to preventing Type 1 diabetes? A recent study shows that IDE deficiency in mice reduces autoreactive immune cells and insulin-specific immune responses, protecting pancreatic cells from autoimmune destruction and lowering Type 1 diabetes risk. Could IDE be a potential target for autoimmune diabetes therapies?

سعودي ولي الفخر🇸🇦1 year ago

متى نرى هذا العلاج النهائي في الأسواق؟؟

Swati Rights1 year ago

While it gives a lot of optimism I'm also wondering what impact it will have in terms of side effects that may trigger new autoimmune conditions, affect organs like the kidney, liver and heart, or produce conditions like cancer or bone affliction later Is there any literature ?

Brady Gretch1 year ago

@BreakthroughT1D Thank you for sharing this great news with a text and video post!

Rachel Harman1 year ago

I would love for my son to be a part of this! He is only 12 and struggling with type one.

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