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Can you stop taking PrEP and just use Doxy-PEP instead? No—because they protect you from different things. 💊 PrEP helps prevent HIV. 💊 Doxy-PEP can help reduce the risk of some bacterial STIs, including chlamydia and syphilis, when prescribed and taken correctly after sex. Doxy-PEP does not prevent HIV,...

18,457 Aufrufe • vor 22 Tagen •via X (Twitter)

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Getting my 2nd Dose Bexsero vaccine today. Protecting against meningococcal B—and maybe giving us a new tool in the STI fight too. Doxycycline PEP works amazingly for syphilis and chlamydia, cutting risk by up to 80–90%. But for gonorrhea, real-world data show protection drops to as low as 10–20%. That’s where Bexsero (MenB-4C) comes in. It was designed for Neisseria meningitidis, but emerging evidence shows it also offers cross-protection against Neisseria gonorrhoeae—the bacteria that causes gonorrhea—cutting infection rates by around 30–40%. Large U.S. studies (NYC + Philadelphia) found full Bexsero vaccination was ~40% effective against gonorrhea, and partial vaccination ~26% effective. Meta-analyses echo these findings, with pooled protection rates of 33–47%. The ANRS DOXYVAC trial in France even showed both Doxy-PEP and Bexsero significantly lowered STI incidence—proof that stacking protection works. Smart protection means using every tool we have: Doxy-PEP for syphilis and chlamydia Bexsero to help lower gonorrhea risk Gardasil 9 to protect against HPV Condoms, regular STI screening, and PrEP for full coverage Because safer sex is smarter sex. —Sex Doctor Deano Sources: CDC Clinical Guidelines on Doxycycline Post-Exposure Prophylaxis (2024) — CDC MMWR RR7302a1 Effectiveness of 4CMenB (Bexsero) against Gonorrhea, NYC + Philadelphia — PMC10227473 Systematic Review: MenB-4C Cross-Protection Against Gonorrhea — PMC11782638 Lancet Infectious Diseases: MenB Vaccine and Gonorrhea Risk Reduction — The Lancet, 2024 Healthy Vaccinee Bias in MenB Studies — PMC10175191 ANRS DOXYVAC Trial (Vaccine + DoxyPEP in MSM on PrEP) — EATG Summary Comprehensive Review of Doxy-PEP Efficacy for STIs — ScienceDirect 2024

Dr. Deano

68,387 Aufrufe • vor 9 Monaten

Culture is genetic because behavior is genetic. This beaver never saw a dam in its life. No beavers or anything else ever taught it to build a dam. It wants to build a dam because it is a beaver. Many beavers together build a big dam. That is beaver culture. Humans are not different. Nothing is different. This is what life is. This is how life works. Your body is your mind. A caterpillar wants to build a chrysalis. A bee wants to build a hive. A lion wants to build a pride. You are not special. You are not above your nature. you are INSIDE of it. The thoughts that we think are genetic thoughts. The crimes we commit are genetic crimes. The art we create is genetic art. Just like this beaver, you can give the animal different sticks and it will build a different dam, but it will always build a dam. And you can give humans different "education," but the human will always use it to do what its genes tell it to do. This is the first big answer that you need. This is the biggest piece of the puzzle. This is how to understand people 90% of the way. You just... notice what they do, and get out of the way, and watch them do it. And if they need sticks, you give them sticks. And if you don't like what they do, you have to get away from them. You cannot train dam-building into them or out of them any more than you can with a beaver. A beaver wants to build a dam because it is a beaver. Whatever you see people build, that's what they wanted to build from the sticks they got in the river they were in. Stop pretending you can change it.

hoe_math = PsychoMath

1,189,824 Aufrufe • vor 11 Monaten

I’d break the Zlatan issue for many people including yourself. Narratives have traveled and I’ve come to conclude that many of you don’t even know what happened with Zlatan at Barcelona. Zlatan’s major issue was with Pep, he had no single issue with Messi, none. Till date, he maintains that beef with Pep. On Piers Morgan, Zlatan said the mistake he did when he got to Barcelona was trying to fit in. He got off a wrong start with Pep because he drove a Ferrari to training. In his words, he said Pep told him that, in this place, players don’t drive a Ferrari. Zlatan said he didn’t drive his car for 7-8 months just to please Pep and try to fit in, which was his biggest regret. Zlatan said he wasn’t performing and went to see Pep in his office. Firstly he went to meet the higher people up there in the hierarchy, but they told him that they can’t interfere and he should speak to Pep himself. He went to meet Pep and told him that the new formation does not favor him. By the way, this is absolutely normal. I have attacked a video to Salah talking with Slot. In fact, you could hear Salah towards the end of that video say he was going to speak to Slot so they could change formations. This is normal in professional football. Players speak to their coaches, especially the big players. Zlatan said the formation does not give him more freedom and it won’t get the best out of him. It’s best he does not play because he’s not performing, Pep is also egoistic, he benched Zlatan for 4 games in a row after that meeting. Zlatan said he created fire afterwards, he started bringing his Ferrari to training and parking it in front of Pep’s office 😭. He said when he went to Manchester United, Pep was at City and Pep will never look him in the eye. I have been able to establish that Zlatan’s problem at Barcelona was Pep, he said it himself and this is the link. I don’t do GOAL, I do facts. ( How does Messi come into this? Zlatan, in his book, said Messi spoke to Pep about switching formations, this formation switch is what affected him. He was playing better in the previous formation, and scoring. This new formation meant he had no freedom and that’s what he said on Piers Morgan, he went to see Pep. This thing Zlatan said is what you guys have been running with. You & I are not privy to the conversation Messi had with Pep. Both parties have never addressed this before to give their side of the story, if they have, you can share me a link of them saying it just like I shared you that link (not screenshots from GOAL please, be serious for once). If any of their mates have addressed this before, please share too. Again, Zlatan’s issue at Barcelona was with Pep right from day 1 of driving a Ferrari, this has nothing to do with Messi. Let’s assume Messi spoke to Pep on changing formation, and Pep agreed, it’s on Pep and he’s the manager. Messi speaking to his manager is normal, just like Zlatan going to speak with Pep. If you listen to the video I attached of Salah, he clearly mentions he spoke to Slot on not defending, and he will still speak to Slot for them to adapt their formation because oppositions are finding out. Players are in constant communication with their managers. Whatever they spoke about, Pep is the manager not Messi. Easy with your bragging too, telling me you don’t just write and no one should dare you to bring evidences. After spending hours in your research, you even slept overnight, and the source you could reference is “Goal”😭 Listen to Zlatan talk about why he loves Messi so much, this was few days ago by the way Another Stop creating issues where there’s none.

TobyWrites

100,025 Aufrufe • vor 2 Monaten

This is one way they're going to fill those ICE warehouses IMO: "With PCR [they] can declare you a carrier of any possible virus...[and] certain viruses are... written into law as quarantineable.... [So they can] violate your constitutional rights and imprison you without due cause." This clip of retired pharma R&D executive Sasha Latypova (sashalatypova.substack.com "Due Diligence and Art") is taken from an interview with Shannon Joy (Shannon Joy) posted to Rumble on February 10, 2026. ----------------Partial transcription of clip--------------- "With PCR, we can declare you a carrier of any possible virus. Any possible virus on the planet existing now, imaginary, non-imaginary, the one we just drew in a cartoon. We can diagnose you with that virus with the PCR, and then depends on how. "And also the US law is set out such a way that certain viruses are actually written into law as quarantineable. And quarantineable means the government can violate your constitutional rights and imprison you without due cause. And this is why they build those centers in the marketplace mall, by the way. "So this, the detention center. There are several viruses, including influenza and Covid and a few others that are written into the US Law that gives CDC and the military unlimited power to. To detain you, take you off a cruise ship like, just like they did with those, Grand Princes and, the other. Yeah, International Princess. I forget those two. And, send you to the military base where you will be treated against your will and killed there and then declared you dead from COVID or disease acts or whatever next virus we're going to have on the menu. "And so that's why. That's why these, these are, you know, these are not just to harvest people's bodies. That's. That's a given. Yeah, they've been doing that, that for ages. Now this is also designed to imprison anyone by declaring them a carrier of a, of an emergency threat virus. And so imprison any dissident, anybody the state wants to get rid of is a perfectly easy way to do... And also broadly establish control measures. "So if they want to roll out CBDC programmable money, this is a way to do it, by tying it to your health records. They already tying everything to the. To the health records. They're already centrally collecting all the health data through the electronic medical records, which. Which, you know, technically the practice of medicine, including these electronic medical records, supposed to be a purview of the state regulation, not federal regulation. But... we have blown past that a long time ago. "And now all these records, health records, have been centrally sucked into federal databases, which are then turned over to Palantir to target you, to the sum up, to AI, to set up some AI to surveil you. So now they can force you, especially with people with children, they can threaten them, and you've been participating in those, in those cases many times where they can threaten the parent if they deny some sort of a health intervention. "And, you know, and parents will comply just because they're afraid for their children. But guess what? They can also test your child for some novel virus. Find it, and then you. And then you become it. Then you become the sentinel case. Then you become that case that they need to demonstrate there is a pandemic... Lock down the whole community, do whatever they wish there. It becomes an unlimited scenario for totalitarian dystopia."

Sense Receptor

14,513 Aufrufe • vor 6 Monaten

I asked Garry Tan how to use meta prompting to get better at AI: "My partners at YC Jared Friedman and Pete Koomen showed me how to do this. You can take almost anything that you do all the time and just drop it into a context window. And then say, “Here’s a bunch of inputs and outputs." And maybe you also add a bunch of notes. And then you tell it, “Write me a prompt that can act as an agent that takes this input and makes this output over here.” You can do this for almost any type of knowledge work. And you can even introspect. "What are things you notice that I did to convert this from the input to the output?”. And then you can just start using the prompt. Initially, it’s going to suck. Because it’s just not that smart yet. But what’s funny is now, I also use it to Iterate my writing. You can be very direct, "I would never say that", "Don’t say it like this", or "Oh, you used the long word there, use the short word". Just speak to it conversationally. And then when you're happy with the output, you can use that new output to make a new prompt. "Based on this conversation, give me a better initial prompt that incorporates all the things we talked about." And you can do this with literally everything. And in theory, there’s so much it applies to that people do day-to-day. You could use it for tweets. You could use it for editing podcasts. You can use it for pretty much everything. I have a folder of prompts that I use all the time. My YouTube prompt is on v27 or something. I'll go through this process with all the different max models. I'll use GPT 5.2 Pro. I’ll use Grok. I'll use Claude. Then, I’ll take all the outputs from all the models and put them into Claude and say "Here’s my prompt, here’s the output from four LLMs, including yourself. Rate each response and tell me what the pros and cons of each approach are." And I usually say "give it to me in numbered form". And then you can agree with one, disagree with two, tell it three is this or that. And then after that, you say given all of this, synthesize it."

The Peel

51,632 Aufrufe • vor 5 Monaten