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. David Sinclair is working towards a future in which we take a pill for 4 weeks and get younger...

73,037 Aufrufe • vor 1 Jahr •via X (Twitter)

10 Kommentare

Profilbild von Peter H. Diamandis, MD
Peter H. Diamandis, MDvor 1 Jahr

full episode here:

Profilbild von Anwarino
Anwarinovor 1 Jahr

@davidasinclair Whenever someone now predicts something will happen 10 years into the future, my working assumption is that it will happen much much sooner

Profilbild von Jeff Lewis
Jeff Lewisvor 1 Jahr

@davidasinclair Faster please

Profilbild von Most interesting man on X ☦️
Most interesting man on X ☦️vor 1 Jahr

@davidasinclair Faster please. Some of us may not have 10 years

Profilbild von Endrina Pavlić
Endrina Pavlićvor 1 Jahr

@davidasinclair Perfect…future is great 👍

Profilbild von Joel Collinson
Joel Collinsonvor 1 Jahr

@davidasinclair Great episode. The near-term future is bright.

Profilbild von Stephen Schifani
Stephen Schifanivor 1 Jahr

@davidasinclair Fascinating. So many questions. I began typing some out, but there are too many.

Profilbild von Faith Cited
Faith Citedvor 1 Jahr

@davidasinclair Yes, the day you’re dreaming for will come and then you’ll seek death and not find it.

Profilbild von İsmail Keskin
İsmail Keskinvor 1 Jahr

@davidasinclair This and the robotic servants are the only tech I am excited about honestly. No space travel, FSD, quantum computing, nanomaterials.

Profilbild von Taylor-Valmere Theory of Awareness
Taylor-Valmere Theory of Awarenessvor 1 Jahr

I LOVE every video you put out, Pete. (I can call you Pete, right? Feels like we’re on a first name basis after watching all your vids and summits). Dr. Sinclair is one of my very favorite people you put in front and center for us. So much appreciation for the level-headed optimism you are bringing to medical and AI advancement.

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David Sinclair's lab may have just found the $100 pill that reverses aging. Over the holidays, his team ran what he calls a "hail mary experiment." They gave old mice a "longevity" cocktail three times a week for 4 weeks. He didn't reveal what's in it - only that it contained molecules that work on the four longevity pathways that control the epigenome. They weren't expecting any significant results. Yet every treated mice came back physiologically younger while the controls didn't. Biological age clocks confirmed the reversal. This changes the trajectory for longevity medicine. The gene therapy his company is taking into human trials costs over $10 million to manufacture per batch. It requires a direct injection into the target organ. These oral molecules cost roughly $100 for a month's course. If they're able to put these molecules into a pill that patients can take instead of them using a multi-million dollar gene therapy, they'd save a ton of money. "Imagine in 10 years you just take a pill for 4 weeks and you get younger. That's what we're headed towards. I can see how this is going to happen." The proof of concept exists in animals. Now it's a race to get it into humans. — David Sinclair (David Sinclair) on Peter Diamandis' (Peter H. Diamandis, MD) Moonshots podcast PS. David Sinclair is speaking at SynBioBeta on May 6th this year, discussing the science of slowing and reversing aging. If longevity is the world you're in, the investors, partners, and scientists shaping this space will be in the room. You won't want to miss it:

John Cumbers

56,080 Aufrufe • vor 3 Monaten