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🫀 Detecting Diffuse Non-Calcified Coronary Atherosclerosis with Photon Counting CT: Seeing What Conventional CT Often Misses In coronary CTA, the hardest disease to detect is not focal stenosis. It’s diffuse, non-calcified atherosclerosis. No obvious narrowing. No calcium. Just subtle, continuous vessel wall involvement. This is where Photon-Counting CT (PCCT)...

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Dr. Filippo Cademartiri

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🫀 Why Photon-Counting CT Is the New Standard for Non-Invasive Stent Imaging Because “Uninterpretable” Should No Longer Be Acceptable For years, coronary stent evaluation by CTA was often dismissed: “Too much blooming.” “Too much metal artifact.” “Just send the patient to invasive angiography.” That paradigm belongs to the past. Photon-Counting CT (PCCT) is changing non-invasive stent imaging from a limitation into a true diagnostic tool. 🧠 Why conventional CT struggles With standard EID-CT: - Metallic struts create significant blooming - Partial volume effects obscure the intrastent lumen - Small stents become nearly unreadable - Motion artifacts worsen proximal and ostial evaluation The result? 👉 Many stents are labeled “non-diagnostic” 👉 Patients are sent to unnecessary invasive angiography ⚡ Why PCCT changes everything -Ultra-high spatial resolution - Sharper visualization of stent struts - Clear assessment of the true intrastent lumen Reduced blooming artifacts - Metal appears closer to reality - Less artificial lumen narrowing High temporal resolution - Better imaging of proximal, ostial, and fast-moving segments - Reduced motion blur around the stent High iodine concentration contrast (400 mg I/mL) - Strong intraluminal enhancement - Better contrast between lumen and metal - Spectral capability Additional confidence separating iodine signal from stent artifact 🎯 The clinical shift From: “Can we read this stent?” To: “We can characterize it with confidence.” - Restenosis - Stent patency - Aneurysm repair - Complex proximal LAD interventions - Left main and bifurcation stents >>>> all become more reliably assessable. From invasive default to non-invasive confidence and convenience. From metallic blur to diagnostic clarity. That’s why PCCT is becoming the new standard for coronary stent imaging. ⚡🫀 #PhotonCountingCT #PCCT #CoronaryCTA #StentImaging #CardiacCT #CoronaryStent #UltraHighResolution #RadiologyInnovation #yesCCT
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🫀 Why Photon-Counting CT Is the New Standard for Non-Invasive Stent Imaging Because “Uninterpretable” Should No Longer Be Acceptable For years, coronary stent evaluation by CTA was often dismissed: “Too much blooming.” “Too much metal artifact.” “Just send the patient to invasive angiography.” That paradigm belongs to the past. Photon-Counting CT (PCCT) is changing non-invasive stent imaging from a limitation into a true diagnostic tool. 🧠 Why conventional CT struggles With standard EID-CT: - Metallic struts create significant blooming - Partial volume effects obscure the intrastent lumen - Small stents become nearly unreadable - Motion artifacts worsen proximal and ostial evaluation The result? 👉 Many stents are labeled “non-diagnostic” 👉 Patients are sent to unnecessary invasive angiography ⚡ Why PCCT changes everything -Ultra-high spatial resolution - Sharper visualization of stent struts - Clear assessment of the true intrastent lumen Reduced blooming artifacts - Metal appears closer to reality - Less artificial lumen narrowing High temporal resolution - Better imaging of proximal, ostial, and fast-moving segments - Reduced motion blur around the stent High iodine concentration contrast (400 mg I/mL) - Strong intraluminal enhancement - Better contrast between lumen and metal - Spectral capability Additional confidence separating iodine signal from stent artifact 🎯 The clinical shift From: “Can we read this stent?” To: “We can characterize it with confidence.” - Restenosis - Stent patency - Aneurysm repair - Complex proximal LAD interventions - Left main and bifurcation stents >>>> all become more reliably assessable. From invasive default to non-invasive confidence and convenience. From metallic blur to diagnostic clarity. That’s why PCCT is becoming the new standard for coronary stent imaging. ⚡🫀 #PhotonCountingCT #PCCT #CoronaryCTA #StentImaging #CardiacCT #CoronaryStent #UltraHighResolution #RadiologyInnovation #yesCCT

Dr. Filippo Cademartiri

19,742 Aufrufe • vor 1 Monat

PHOTON COUNTING CT is NOT a better CT It is a NEW imaging modality Photon Counting CT (PCCT) represents a transformative leap in medical imaging, not only as a molecular imaging modality but also as a technology offering ultra-high resolution and functional imaging capabilities. It is fundamentally more than just an enhanced version of traditional CT—PCCT introduces new ways of seeing and understanding the human body, providing critical insights at the molecular, structural, and functional levels. This positions PCCT as a unique imaging modality that requires a fresh approach to technical implementation, operational workflows, and financial planning. Despite the larger upfront investment, PCCT’s ability to drastically reduce downstream healthcare costs makes it a highly valuable investment in the long run. 1. Technical Innovations • Molecular Imaging and Energy Discrimination: Unlike traditional CT, which simply measures the total absorbed energy, PCCT counts individual X-ray photons and differentiates their energy levels. This allows for precise molecular imaging, revealing the composition of tissues and materials at a biochemical level. By distinguishing between different tissue types and contrast agents, PCCT opens up new diagnostic possibilities, such as identifying molecular biomarkers in tumors or distinguishing between stable and unstable plaque in coronary arteries. This capability shifts the focus of imaging from purely anatomical to both anatomical and molecular, offering more comprehensive diagnostic information. • Ultra-High Spatial Resolution: PCCT features significantly smaller detector elements compared to conventional CT scanners, allowing for ultra-high resolution imaging. This means clinicians can visualize fine structures such as microcalcifications in arteries, small lesions in soft tissues, or the intricate architecture of bones. This level of detail was previously unattainable with traditional CT. When combined with molecular imaging, this ultra-high resolution allows for the precise localization and characterization of disease at very early stages, which is essential for early diagnosis and intervention. • Functional Imaging Capabilities: PCCT also excels as a functional imaging modality. By capturing energy-resolved information, PCCT can provide insights into tissue functionality and dynamic physiological processes. For instance, it can detect changes in blood flow, tissue perfusion, and oxygenation without the need for additional contrast agents or scans. This functionality allows for real-time assessment of physiological processes, making it particularly valuable in cardiology, oncology, and neurology for evaluating organ function and monitoring disease progression. • Reduced Noise and Artifact Reduction: Photon-counting technology dramatically reduces electronic noise and imaging artifacts, such as beam hardening, resulting in clearer and more accurate images. The ability to deliver ultra-high resolution images with minimal artifacts improves diagnostic accuracy, reducing the need for repeat scans and ensuring that even subtle abnormalities are detected. 2. Operational Considerations • New Workflow for Molecular, High-Resolution, and Functional Imaging: The integration of molecular, ultra-high resolution, and functional imaging into routine clinical workflows introduces complexity that requires adaptation. Radiologists and technicians need specialized training to interpret and analyze multi-energy datasets that include molecular and functional information. PCCT produces a vast amount of detailed data, requiring clinicians to adopt new imaging protocols and refine their diagnostic approaches to fully leverage its capabilities. • Post-Processing and Data Management: PCCT generates richer, more complex datasets, which necessitates advanced post-processing tools and data management systems. Existing PACS and imaging software may not be equipped to handle such large volumes of data or to process functional and molecular information effectively. This means healthcare institutions must invest in robust IT infrastructure, including upgraded software and storage solutions, as well as provide additional training for staff on new imaging analysis techniques. • Revised Clinical Protocols: The molecular, functional, and ultra-high resolution imaging capabilities of PCCT will likely prompt changes in clinical protocols. For instance, the need for contrast agents may be reduced, simplifying patient preparation and decreasing the risk of adverse reactions. Additionally, the ability to monitor physiological functions in real-time through functional imaging could lead to more dynamic diagnostic procedures, such as assessing the effectiveness of interventions or treatments in real-time. 3. Financial Impact • Higher Initial Investment: PCCT systems are more expensive than traditional CT scanners due to their advanced technology, which includes photon-counting detectors and the computational power required for high-resolution, molecular, and functional imaging. While this upfront cost is significant, it is crucial to view it in the broader context of the downstream benefits and cost reductions that PCCT offers. • Downstream Cost Reductions: Although the initial capital investment is higher, PCCT’s ability to combine molecular, functional, and ultra-high resolution imaging leads to substantial reductions in downstream healthcare costs. Its superior diagnostic accuracy minimizes the need for follow-up tests, repeat scans, or invasive diagnostic procedures, such as diagnostic coronary angiographies. For example, in cardiology, PCCT can precisely differentiate between types of coronary plaque, reducing the need for invasive procedures to assess risk. • Lower Overall Healthcare Expenditures: By enabling earlier, more accurate diagnoses, PCCT can reduce the overall cost of patient care. Early detection of disease, particularly through its molecular and functional imaging capabilities, allows for more targeted treatments, potentially preventing the need for more aggressive and expensive interventions down the line. For instance, early-stage tumor detection via molecular imaging could lead to less invasive treatments, reducing hospital stays and improving patient outcomes, ultimately driving down healthcare costs. • Increased ROI Through Enhanced Patient Outcomes: Over time, the combination of molecular, functional, and ultra-high resolution imaging enhances diagnostic precision, which translates into better patient outcomes. Improved diagnostic accuracy reduces the incidence of unnecessary procedures, minimizes treatment delays, and results in more personalized and effective care. This leads to increased patient satisfaction, better healthcare outcomes, and greater patient throughput—all factors that improve the institution’s return on investment (ROI). • Competitive Advantage and New Revenue Streams: By adopting PCCT, healthcare institutions position themselves at the forefront of advanced imaging technologies. The ability to offer molecular, functional, and ultra-high resolution imaging creates a competitive advantage, attracting more complex and high-value cases. This can boost the institution’s reputation for excellence in diagnostics, leading to increased referrals, new patient populations, and expanded revenue opportunities. Summary Photon Counting CT (PCCT) is not just an evolution of existing CT technology—it is a molecular, ultra-high resolution, and functional imaging modality that fundamentally transforms the diagnostic landscape. Its ability to capture detailed molecular data, visualize minute anatomical structures with ultra-high resolution, and provide real-time functional imaging opens new possibilities for earlier and more precise diagnoses. While the financial investment in PCCT is larger, the reduction in downstream healthcare costs through improved diagnostic accuracy, fewer unnecessary interventions, and earlier disease detection far outweighs the initial expense. For institutions committed to advancing patient care and improving long-term financial outcomes, PCCT is an essential investment in the future of medical imaging. The video attached shows a patient accessing the Hospital for ACS. PCCT can provide ALL the imaging information of the concurrent imaging modalities (CXR, CAG, Echo, CMR) that you see around it... that's a lot! #PhotonCountingCT #MolecularImaging #UltraHighResolution #FunctionalImaging #FutureOfImaging #AdvancedMedicalImaging #EarlyDiseaseDetection #InnovativeCT #CuttingEdgeHealthcare #PrecisionDiagnostics #HealthcareInnovation #MedicalTechnology #CostEffectiveImaging #NextGenCT #PatientCareRevolution
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PHOTON COUNTING CT is NOT a better CT It is a NEW imaging modality Photon Counting CT (PCCT) represents a transformative leap in medical imaging, not only as a molecular imaging modality but also as a technology offering ultra-high resolution and functional imaging capabilities. It is fundamentally more than just an enhanced version of traditional CT—PCCT introduces new ways of seeing and understanding the human body, providing critical insights at the molecular, structural, and functional levels. This positions PCCT as a unique imaging modality that requires a fresh approach to technical implementation, operational workflows, and financial planning. Despite the larger upfront investment, PCCT’s ability to drastically reduce downstream healthcare costs makes it a highly valuable investment in the long run. 1. Technical Innovations • Molecular Imaging and Energy Discrimination: Unlike traditional CT, which simply measures the total absorbed energy, PCCT counts individual X-ray photons and differentiates their energy levels. This allows for precise molecular imaging, revealing the composition of tissues and materials at a biochemical level. By distinguishing between different tissue types and contrast agents, PCCT opens up new diagnostic possibilities, such as identifying molecular biomarkers in tumors or distinguishing between stable and unstable plaque in coronary arteries. This capability shifts the focus of imaging from purely anatomical to both anatomical and molecular, offering more comprehensive diagnostic information. • Ultra-High Spatial Resolution: PCCT features significantly smaller detector elements compared to conventional CT scanners, allowing for ultra-high resolution imaging. This means clinicians can visualize fine structures such as microcalcifications in arteries, small lesions in soft tissues, or the intricate architecture of bones. This level of detail was previously unattainable with traditional CT. When combined with molecular imaging, this ultra-high resolution allows for the precise localization and characterization of disease at very early stages, which is essential for early diagnosis and intervention. • Functional Imaging Capabilities: PCCT also excels as a functional imaging modality. By capturing energy-resolved information, PCCT can provide insights into tissue functionality and dynamic physiological processes. For instance, it can detect changes in blood flow, tissue perfusion, and oxygenation without the need for additional contrast agents or scans. This functionality allows for real-time assessment of physiological processes, making it particularly valuable in cardiology, oncology, and neurology for evaluating organ function and monitoring disease progression. • Reduced Noise and Artifact Reduction: Photon-counting technology dramatically reduces electronic noise and imaging artifacts, such as beam hardening, resulting in clearer and more accurate images. The ability to deliver ultra-high resolution images with minimal artifacts improves diagnostic accuracy, reducing the need for repeat scans and ensuring that even subtle abnormalities are detected. 2. Operational Considerations • New Workflow for Molecular, High-Resolution, and Functional Imaging: The integration of molecular, ultra-high resolution, and functional imaging into routine clinical workflows introduces complexity that requires adaptation. Radiologists and technicians need specialized training to interpret and analyze multi-energy datasets that include molecular and functional information. PCCT produces a vast amount of detailed data, requiring clinicians to adopt new imaging protocols and refine their diagnostic approaches to fully leverage its capabilities. • Post-Processing and Data Management: PCCT generates richer, more complex datasets, which necessitates advanced post-processing tools and data management systems. Existing PACS and imaging software may not be equipped to handle such large volumes of data or to process functional and molecular information effectively. This means healthcare institutions must invest in robust IT infrastructure, including upgraded software and storage solutions, as well as provide additional training for staff on new imaging analysis techniques. • Revised Clinical Protocols: The molecular, functional, and ultra-high resolution imaging capabilities of PCCT will likely prompt changes in clinical protocols. For instance, the need for contrast agents may be reduced, simplifying patient preparation and decreasing the risk of adverse reactions. Additionally, the ability to monitor physiological functions in real-time through functional imaging could lead to more dynamic diagnostic procedures, such as assessing the effectiveness of interventions or treatments in real-time. 3. Financial Impact • Higher Initial Investment: PCCT systems are more expensive than traditional CT scanners due to their advanced technology, which includes photon-counting detectors and the computational power required for high-resolution, molecular, and functional imaging. While this upfront cost is significant, it is crucial to view it in the broader context of the downstream benefits and cost reductions that PCCT offers. • Downstream Cost Reductions: Although the initial capital investment is higher, PCCT’s ability to combine molecular, functional, and ultra-high resolution imaging leads to substantial reductions in downstream healthcare costs. Its superior diagnostic accuracy minimizes the need for follow-up tests, repeat scans, or invasive diagnostic procedures, such as diagnostic coronary angiographies. For example, in cardiology, PCCT can precisely differentiate between types of coronary plaque, reducing the need for invasive procedures to assess risk. • Lower Overall Healthcare Expenditures: By enabling earlier, more accurate diagnoses, PCCT can reduce the overall cost of patient care. Early detection of disease, particularly through its molecular and functional imaging capabilities, allows for more targeted treatments, potentially preventing the need for more aggressive and expensive interventions down the line. For instance, early-stage tumor detection via molecular imaging could lead to less invasive treatments, reducing hospital stays and improving patient outcomes, ultimately driving down healthcare costs. • Increased ROI Through Enhanced Patient Outcomes: Over time, the combination of molecular, functional, and ultra-high resolution imaging enhances diagnostic precision, which translates into better patient outcomes. Improved diagnostic accuracy reduces the incidence of unnecessary procedures, minimizes treatment delays, and results in more personalized and effective care. This leads to increased patient satisfaction, better healthcare outcomes, and greater patient throughput—all factors that improve the institution’s return on investment (ROI). • Competitive Advantage and New Revenue Streams: By adopting PCCT, healthcare institutions position themselves at the forefront of advanced imaging technologies. The ability to offer molecular, functional, and ultra-high resolution imaging creates a competitive advantage, attracting more complex and high-value cases. This can boost the institution’s reputation for excellence in diagnostics, leading to increased referrals, new patient populations, and expanded revenue opportunities. Summary Photon Counting CT (PCCT) is not just an evolution of existing CT technology—it is a molecular, ultra-high resolution, and functional imaging modality that fundamentally transforms the diagnostic landscape. Its ability to capture detailed molecular data, visualize minute anatomical structures with ultra-high resolution, and provide real-time functional imaging opens new possibilities for earlier and more precise diagnoses. While the financial investment in PCCT is larger, the reduction in downstream healthcare costs through improved diagnostic accuracy, fewer unnecessary interventions, and earlier disease detection far outweighs the initial expense. For institutions committed to advancing patient care and improving long-term financial outcomes, PCCT is an essential investment in the future of medical imaging. The video attached shows a patient accessing the Hospital for ACS. PCCT can provide ALL the imaging information of the concurrent imaging modalities (CXR, CAG, Echo, CMR) that you see around it... that's a lot! #PhotonCountingCT #MolecularImaging #UltraHighResolution #FunctionalImaging #FutureOfImaging #AdvancedMedicalImaging #EarlyDiseaseDetection #InnovativeCT #CuttingEdgeHealthcare #PrecisionDiagnostics #HealthcareInnovation #MedicalTechnology #CostEffectiveImaging #NextGenCT #PatientCareRevolution

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The SCAPIS study published in JAMA ~25,000 🇸🇪 participants, ~8 years follow-up. Adding coronary CT angiography #CCTA plaque information improved event prediction beyond clinical risk and calcium score. This is the first study showing the added value of CCTA on top of the calcium score for risk prediction. 🎯 What to look for: lipidic soft (non-calcified) plaque. 👀 Practical takeaway: Consider a CT angiography for risk stratification on top of the calcium score. Link: 🎥 Posting my avatar summarizing the study.

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Brandy

125,840 Aufrufe • vor 3 Monaten

The greatest criminal enterprises of our lifetime have one thing in common. ✔️ Russia hoax ✔️ J6 ✔️ Mar-a-Lago raid ✔️ Biden auto pen ✔️ 2020 election fraud ✔️ Epstein network ✔️ COVID fraud ✔️ Benghazi gun running ✔️ Ukraine impeachment hoax Ask the DOJ how many real perpetrators have been arrested. The answer is zero. #AccountabilityNow #RenzLaw #TheTomRenzShow
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The greatest criminal enterprises of our lifetime have one thing in common. ✔️ Russia hoax ✔️ J6 ✔️ Mar-a-Lago raid ✔️ Biden auto pen ✔️ 2020 election fraud ✔️ Epstein network ✔️ COVID fraud ✔️ Benghazi gun running ✔️ Ukraine impeachment hoax Ask the DOJ how many real perpetrators have been arrested. The answer is zero. #AccountabilityNow #RenzLaw #TheTomRenzShow

Tom Renz

48,091 Aufrufe • vor 6 Monaten

Face card✔️body type✔️hair✔️height ✔️and likability ✔️.This is how you SLAY in a suit and make it fly off the shelves! Princess Catherine is truly the ultimate style icon. She's just that girl! Absolute legend! 🌟✨👸
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Face card✔️body type✔️hair✔️height ✔️and likability ✔️.This is how you SLAY in a suit and make it fly off the shelves! Princess Catherine is truly the ultimate style icon. She's just that girl! Absolute legend! 🌟✨👸

Julia Unleashed

41,149 Aufrufe • vor 1 Jahr

#GoProMAX2 is here 🚨 Industry-leading, true 8K 360 video delivers 21% more resolution than the competition, resulting in unmatched image quality that you only get from #GoPro. ✔️ Emmy® Award-Winning 360 technology ✔️ The only true 8K 360 camera. No misleading upscaling, no unusable black pixels, no AI-generated content ✔️ Twist + go replaceable lenses made from water-repelling optical glass. No tools or calibration required to swap ✔️ 5.6K60 + 4K100 for up to 4x slo-mo in 360 ✔️ 10-Bit color, GP-Log encoding, + with GoPro Labs, category-leading 300mbps bitrate ✔️ Seamless, invisible pole shots thanks to a new, back-to-back lens design + built-in 1/4-20 mount ✔️ Easy AI-powered editing tools with intuitive Reframe modes that anyone can use ✔️ Automatic POV + Selfie modes for minimal editing, while retaining full 360 flexibility ✔️ Most-in-class 6 microphones that unlock true-to-life spatial audio with innovative Audio Field of View ✔️ 23% larger, 1960mAh cold-weather Enduro battery ✔️ 360 Night Effects for creative capture in the dark ✔️ Sleek form factor for noninvasive mounting in action sports ✔️ Unbreakable Max #HyperSmooth with 360° Horizon Lock ✔️ Rugged + waterproof to 16ft (5m) ✔️ Quick-release magnetic mounting + compatibility with GoPro's entire accessory ecosystem ✔️ Single lens 4K60 video in Max HyperView at 180° FOV ✔️ 29MP 360 photos for cropping + zooming without quality loss ✔️ Bluetooth® audio connectivity for wireless microphones ✔️ Lightning-fast transfer speeds to the GoPro Quik App with Wifi 6 + BLE 5.3 🇺🇸 Designed in the USA Enhanced by a GoPro Subscription: ✔️ AI-edited highlight videos automatically sent to your phone ✔️ Unlimited cloud storage at 100% quality ✔️ No-questions-asked camera replacement 📦 Pre-order today, with free shipping and a free 1-year GoPro Subscription at Orders will ship on or before September 30th. *MAX2 delivers up to 21% more video resolution compared to competitive 360 cameras’ native maximum video resolution before they up-scale.
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#GoProMAX2 is here 🚨 Industry-leading, true 8K 360 video delivers 21% more resolution than the competition, resulting in unmatched image quality that you only get from #GoPro. ✔️ Emmy® Award-Winning 360 technology ✔️ The only true 8K 360 camera. No misleading upscaling, no unusable black pixels, no AI-generated content ✔️ Twist + go replaceable lenses made from water-repelling optical glass. No tools or calibration required to swap ✔️ 5.6K60 + 4K100 for up to 4x slo-mo in 360 ✔️ 10-Bit color, GP-Log encoding, + with GoPro Labs, category-leading 300mbps bitrate ✔️ Seamless, invisible pole shots thanks to a new, back-to-back lens design + built-in 1/4-20 mount ✔️ Easy AI-powered editing tools with intuitive Reframe modes that anyone can use ✔️ Automatic POV + Selfie modes for minimal editing, while retaining full 360 flexibility ✔️ Most-in-class 6 microphones that unlock true-to-life spatial audio with innovative Audio Field of View ✔️ 23% larger, 1960mAh cold-weather Enduro battery ✔️ 360 Night Effects for creative capture in the dark ✔️ Sleek form factor for noninvasive mounting in action sports ✔️ Unbreakable Max #HyperSmooth with 360° Horizon Lock ✔️ Rugged + waterproof to 16ft (5m) ✔️ Quick-release magnetic mounting + compatibility with GoPro's entire accessory ecosystem ✔️ Single lens 4K60 video in Max HyperView at 180° FOV ✔️ 29MP 360 photos for cropping + zooming without quality loss ✔️ Bluetooth® audio connectivity for wireless microphones ✔️ Lightning-fast transfer speeds to the GoPro Quik App with Wifi 6 + BLE 5.3 🇺🇸 Designed in the USA Enhanced by a GoPro Subscription: ✔️ AI-edited highlight videos automatically sent to your phone ✔️ Unlimited cloud storage at 100% quality ✔️ No-questions-asked camera replacement 📦 Pre-order today, with free shipping and a free 1-year GoPro Subscription at Orders will ship on or before September 30th. *MAX2 delivers up to 21% more video resolution compared to competitive 360 cameras’ native maximum video resolution before they up-scale.

GoPro

138,409 Aufrufe • vor 8 Monaten

Failure is not an option for Republicans. The American people gave a mandate for change. ✔️ Secure the borders. ✔️ Unleash American energy. ✔️ End the out of control spending. ✔️ Create jobs. ✔️ Rebuild the military.
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Failure is not an option for Republicans. The American people gave a mandate for change. ✔️ Secure the borders. ✔️ Unleash American energy. ✔️ End the out of control spending. ✔️ Create jobs. ✔️ Rebuild the military.

Senator Ted Cruz

103,908 Aufrufe • vor 1 Jahr