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Environmental and molecular control of tissue-specific ionocyte differentiation in zebrafish #DevSIDiversity Research Article by @jupeloggia Piotrowski Lab & co Stowers Institute: 🎥A Nm ionocyte progenitor dividing & the resulting pair invading a neuromast

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The Kennan Institute returns as an independent, non-partisan institute entering a new era of scholarship and statecraft 🎥Watch members of our community reflect on the past, present and future of research and policy analysis on Russia, Ukraine, the South Caucasus & Central Asia
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The Kennan Institute returns as an independent, non-partisan institute entering a new era of scholarship and statecraft 🎥Watch members of our community reflect on the past, present and future of research and policy analysis on Russia, Ukraine, the South Caucasus & Central Asia

The Kennan Institute

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The Labcoat is an awesome addition to the American Century Championship The American Century Championship will award its winner a custom-made lab coat inspired by the green jacket presented at the Masters. The lab coat is a deliberate nod to the groundbreaking work of the scientists at the Stowers Institute for Medical Research, the tournament’s official national charity and primary beneficiary. I doubt I’ll ever win one, but I’m gonna keep tryin’. #accgolf
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The Labcoat is an awesome addition to the American Century Championship The American Century Championship will award its winner a custom-made lab coat inspired by the green jacket presented at the Masters. The lab coat is a deliberate nod to the groundbreaking work of the scientists at the Stowers Institute for Medical Research, the tournament’s official national charity and primary beneficiary. I doubt I’ll ever win one, but I’m gonna keep tryin’. #accgolf

Larry The Cable Guy

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There are now hundreds of genes associated with autism & neurodevelopmental disorders but what key processes in brain development they each disrupt remains unknown. In an article in nature today, we start tackling this question by combining forebrain #assembloids with CRISPR screens to map >400 disease genes onto stages of human cortical interneuron development. Using engineered lines, regionalized neural #organoids and over 1,000 #assembloids, we discovered a group of disease genes that interfere with GABAergic neuron generation or migration, including some surprising disease mechanisms. Check out the video below for details. This work was led by the fearless Xiangling Meng in the lab!! In collaboration with Bassik lab & Georgia Panagiotakos lab! Article here: Supported by the Stanford Brain Organogenesis Center Wu Tsai Neurosciences Institute Stanford Bio-X New York Stem Cell Foundation Research Institute Biohub
1:38

There are now hundreds of genes associated with autism & neurodevelopmental disorders but what key processes in brain development they each disrupt remains unknown. In an article in nature today, we start tackling this question by combining forebrain #assembloids with CRISPR screens to map >400 disease genes onto stages of human cortical interneuron development. Using engineered lines, regionalized neural #organoids and over 1,000 #assembloids, we discovered a group of disease genes that interfere with GABAergic neuron generation or migration, including some surprising disease mechanisms. Check out the video below for details. This work was led by the fearless Xiangling Meng in the lab!! In collaboration with Bassik lab & Georgia Panagiotakos lab! Article here: Supported by the Stanford Brain Organogenesis Center Wu Tsai Neurosciences Institute Stanford Bio-X New York Stem Cell Foundation Research Institute Biohub

Sergiu P. Pasca

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Help measure progress in robotics research: a specific & verifiable physical benchmark for cable routing, part of a broader ManipulationNet effort by Kaiyu Hang (Rice U) and Kenny Kimble (NIST) and others from MIT, Berkeley, CMU, Columbia, UT, Tsinghua...
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Help measure progress in robotics research: a specific & verifiable physical benchmark for cable routing, part of a broader ManipulationNet effort by Kaiyu Hang (Rice U) and Kenny Kimble (NIST) and others from MIT, Berkeley, CMU, Columbia, UT, Tsinghua...

Ken Goldberg

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BREAKING: New Footage Reveals An Israeli Command & Control Centre Hit With A Rocket The short range rocket was fired by Palestinian Islamic Jihad (PIJ) in Khan Younis. A hit is recorded against the site hosting dozens of Israeli invading soldiers.
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BREAKING: New Footage Reveals An Israeli Command & Control Centre Hit With A Rocket The short range rocket was fired by Palestinian Islamic Jihad (PIJ) in Khan Younis. A hit is recorded against the site hosting dozens of Israeli invading soldiers.

MintPress News

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BOEBERT: "Implant aborted baby parts into lab animals? Have you heard of that sort of research?" GOODMAN: "Yeah. We did an analysis a few years ago showing that over 90% of experiments using human fetal tissue and putting them in animals were funded by Fauci's NIAID." 🎥 Lauren Boebert Justin Goodman White Coat Waste Nancy Mace
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BOEBERT: "Implant aborted baby parts into lab animals? Have you heard of that sort of research?" GOODMAN: "Yeah. We did an analysis a few years ago showing that over 90% of experiments using human fetal tissue and putting them in animals were funded by Fauci's NIAID." 🎥 Lauren Boebert Justin Goodman White Coat Waste Nancy Mace

Chief Nerd

6,705,186 görüntüleme • 1 yıl önce

⚡🎉 We are thrilled to introduce VORTEX, an AI-powered computational framework for predicting 3D Spatial Transcriptomics (ST) using 3D tissue images and minimal 2D ST! 🧬 By combining cutting-edge 3D non-destructive tissue imaging with AI, VORTEX imputes the 3D molecular landscape of large tissue samples in a cost-effective and scalable manner. 🧠💡Our approach: By pretraining on diverse 3D morphology–2D transcriptomic pairs from heterogeneous tissue samples, and then fine-tuning on minimal 2D ST data from a volume of interest, VORTEX leverages both generic tissue-specific and sample-specific morphomolecular correlates to predict 3D ST. Congratulations to our superstar co-leads Cristina Almagro Pérez and Andrew H. Song, this was an exciting collaboration with Jonathan Liu Sizun Jiang Ali Bashashati. Preprint: Demo: Read the excellent blog from our superstar grad student Cristina Almagro Pérez: Also see our previous work on 3D Computational Pathology from Andrew H. Song published in Cell last year: Stay tuned for more to come.
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⚡🎉 We are thrilled to introduce VORTEX, an AI-powered computational framework for predicting 3D Spatial Transcriptomics (ST) using 3D tissue images and minimal 2D ST! 🧬 By combining cutting-edge 3D non-destructive tissue imaging with AI, VORTEX imputes the 3D molecular landscape of large tissue samples in a cost-effective and scalable manner. 🧠💡Our approach: By pretraining on diverse 3D morphology–2D transcriptomic pairs from heterogeneous tissue samples, and then fine-tuning on minimal 2D ST data from a volume of interest, VORTEX leverages both generic tissue-specific and sample-specific morphomolecular correlates to predict 3D ST. Congratulations to our superstar co-leads Cristina Almagro Pérez and Andrew H. Song, this was an exciting collaboration with Jonathan Liu Sizun Jiang Ali Bashashati. Preprint: Demo: Read the excellent blog from our superstar grad student Cristina Almagro Pérez: Also see our previous work on 3D Computational Pathology from Andrew H. Song published in Cell last year: Stay tuned for more to come.

Faisal Mahmood

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We're ✨revolutionizing✨the human genome reference. The #HumanPangenome Consortium, co-led by UC Santa Cruz, has just published a draft of a more robust, diverse, and complete reference. This will be a game-changing resource for genomics & health research
1:02

We're ✨revolutionizing✨the human genome reference. The #HumanPangenome Consortium, co-led by UC Santa Cruz, has just published a draft of a more robust, diverse, and complete reference. This will be a game-changing resource for genomics & health research

UC Santa Cruz Genomics Institute

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RAI-939 outperformed industry-leading aerospace material C103 by 125x. In a head-to-head torch test, Purdue Applied Research Institute confirmed that Radical AI’s RAI-939 sample exhibited superior environmental survivability to C103. C103 has been in use since the Apollo program, but its performance limitations and constrained supply have fueled a decades-long search for a replacement. Our lab discovered that replacement in just 16 weeks. Now, we aim to scale up production of the alloy to make bigger components.
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RAI-939 outperformed industry-leading aerospace material C103 by 125x. In a head-to-head torch test, Purdue Applied Research Institute confirmed that Radical AI’s RAI-939 sample exhibited superior environmental survivability to C103. C103 has been in use since the Apollo program, but its performance limitations and constrained supply have fueled a decades-long search for a replacement. Our lab discovered that replacement in just 16 weeks. Now, we aim to scale up production of the alloy to make bigger components.

Radical AI

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🎥 Satraj Bambra (Managing Partner & CIO of Round13 and Rails Co-Founder) on the $19B meltdown: The cascade was "a mechanical failure"—not fraud, created by the potent mix of mispriced oracles and excess leverage.
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🎥 Satraj Bambra (Managing Partner & CIO of Round13 and Rails Co-Founder) on the $19B meltdown: The cascade was "a mechanical failure"—not fraud, created by the potent mix of mispriced oracles and excess leverage.

CoinDesk

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Introducing Omanta (YC S26) the personalized research lab for each patient. Omanta integrates a patient's full medical record, personal genomics, and the latest scientific evidence to understand the molecular drivers of their disease. It maps existing and emerging therapies against their biology. And when the right treatment doesn't exist yet, it launches a personalized campaign to build it. Even the hardest cases rarely have a team dedicated to solving them. Physicians make high-stakes calls with limited time, while data and therapies emerge every week. Science moves fast, but reaching the patient can take years. That's the gap Omanta was built to close. Founders Alfredo Gonzalez, PhD and Ranad Humeidi, PhD spent years on some of the most difficult cancer cases. Alfredo led the personalized therapeutic campaign behind Sid Sijbrandij's complete remission. Together they've worked with leading institutions on personalized vaccines, CAR-T, drug repurposing, expanded access, and continuous molecular monitoring. They've seen what becomes possible when the full force of modern science is organized around one person. They met eight years ago doing early CRISPR cancer research at the Broad Institute of MIT and Harvard. Alfredo Gonzalez (CEO) has a PhD in bioinformatics from UCLA and led research projects across the Broad Institute, UCLA, and Harvard. Ranad Humeidi (CSO) has a PhD in chemical biology from Harvard, and has built and run rare-cancer programs for individual patients when standard options ran out. A research lab, for one. Linked-in: YC Launch:
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Introducing Omanta (YC S26) the personalized research lab for each patient. Omanta integrates a patient's full medical record, personal genomics, and the latest scientific evidence to understand the molecular drivers of their disease. It maps existing and emerging therapies against their biology. And when the right treatment doesn't exist yet, it launches a personalized campaign to build it. Even the hardest cases rarely have a team dedicated to solving them. Physicians make high-stakes calls with limited time, while data and therapies emerge every week. Science moves fast, but reaching the patient can take years. That's the gap Omanta was built to close. Founders Alfredo Gonzalez, PhD and Ranad Humeidi, PhD spent years on some of the most difficult cancer cases. Alfredo led the personalized therapeutic campaign behind Sid Sijbrandij's complete remission. Together they've worked with leading institutions on personalized vaccines, CAR-T, drug repurposing, expanded access, and continuous molecular monitoring. They've seen what becomes possible when the full force of modern science is organized around one person. They met eight years ago doing early CRISPR cancer research at the Broad Institute of MIT and Harvard. Alfredo Gonzalez (CEO) has a PhD in bioinformatics from UCLA and led research projects across the Broad Institute, UCLA, and Harvard. Ranad Humeidi (CSO) has a PhD in chemical biology from Harvard, and has built and run rare-cancer programs for individual patients when standard options ran out. A research lab, for one. Linked-in: YC Launch:

Omanta Health

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A Californian surf & skate-inspired bar has just opened in NQ. 🌊🏄‍♂️ Get your knackered pair of Vans and your long, flowing surf hair ready… the NQ has a new bar inspired by the halcyon days of skating and surfing.
0:40

A Californian surf & skate-inspired bar has just opened in NQ. 🌊🏄‍♂️ Get your knackered pair of Vans and your long, flowing surf hair ready… the NQ has a new bar inspired by the halcyon days of skating and surfing.

Manchester’s Finest

1,756,076 görüntüleme • 2 yıl önce

We are excited to be recruiting a Junior Group Leader to join our Institute. Here Prof Caroline Dive & Claus Jorgensen 🇪🇺🇩🇰 reflect on working in our fantastic research centre alongside colleagues from The Christie NHS, Division of Cancer Sciences and Manchester Cancer Research Centre To apply go to:
1:35

We are excited to be recruiting a Junior Group Leader to join our Institute. Here Prof Caroline Dive & Claus Jorgensen 🇪🇺🇩🇰 reflect on working in our fantastic research centre alongside colleagues from The Christie NHS, Division of Cancer Sciences and Manchester Cancer Research Centre To apply go to:

CRUK Manchester Institute

10,471 görüntüleme • 2 yıl önce

Unreal how few ppl in tech know who Cody Coleman is. Cody’s three CS degrees Massachusetts Institute of Technology (MIT) (BS 4.9 + MS 5.0) & Stanford University (PhD 4.0) are perhaps the LEAST remarkable part Born in a NJ prison, his journey to become co-Founder & CEO of Coactive AI should be known by EVERYONE in our ecosystem!
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Unreal how few ppl in tech know who Cody Coleman is. Cody’s three CS degrees Massachusetts Institute of Technology (MIT) (BS 4.9 + MS 5.0) & Stanford University (PhD 4.0) are perhaps the LEAST remarkable part Born in a NJ prison, his journey to become co-Founder & CEO of Coactive AI should be known by EVERYONE in our ecosystem!

Elliott Robinson

63,992 görüntüleme • 3 yıl önce

What if one of cancer’s most devastating side effects could be reversed? Cancer cachexia is a debilitating wasting syndrome that affects many people with cancer, yet treatment options remain limited. Team CANCAN has published new research in Science Magazine that highlights a previously underappreciated driver of cancer cachexia: localised signals from tumours acting directly on sensory neurons. This is a big step toward reframing cancer cachexia as not only a systemic metabolic condition, but also one shaped by tumour–nerve communication. 🎥 Papagiannakopoulos Lab, Co-Investigator on team CANCAN and team InteroCANCEption, explains the discovery and what it could mean for patients. Read the full paper: --- Team CANCAN is funded by Cancer Research UK and National Cancer Institute through Cancer Grand Challenges.
1:23

What if one of cancer’s most devastating side effects could be reversed? Cancer cachexia is a debilitating wasting syndrome that affects many people with cancer, yet treatment options remain limited. Team CANCAN has published new research in Science Magazine that highlights a previously underappreciated driver of cancer cachexia: localised signals from tumours acting directly on sensory neurons. This is a big step toward reframing cancer cachexia as not only a systemic metabolic condition, but also one shaped by tumour–nerve communication. 🎥 Papagiannakopoulos Lab, Co-Investigator on team CANCAN and team InteroCANCEption, explains the discovery and what it could mean for patients. Read the full paper: --- Team CANCAN is funded by Cancer Research UK and National Cancer Institute through Cancer Grand Challenges.

Cancer Grand Challenges

41,648 görüntüleme • 1 ay önce

Announcing our 2026 Fellows! One is a neuroscientist exploring how the brain computes at a molecular level, another is a bioengineer 3D-printing human tissue. There’s a PhD student working on computational protein design, and an engineer developing robots to build large structures in space – just to name a few of the badasses in our new Fellowship cohort! With this one-year program, we want to support early-career talents advancing important science and tech. We connect them with senior scientists, invite them to our technical workshops, seminars, and Vision Weekends alongside leaders in their fields, and offer platforms for sharing their work. We are incredibly excited to introduce our 2026 Fellows! Longevity Biotechnology • Alex Plesa, Scientist, Harvard University Alex Plesa • Donnacha Fitzgerald, Founder, Origenity Donnacha Fitzgerald • Gianluca Cidonio, Assistant Professor, Sapienza University Gianluca Cidonio • Jakub Lála, PhD Student, Imperial College London Jakub Lála 👨🏻‍🍳🥯 • Léo Lopez, Staff Scientist, Tufts University • Nick Schaum, Postdoc & Co-Founder, University of Cambridge & Neurotechnology • Avery Krieger, Founder & CEO, Constellation Systems Avery Krieger • Constanze Albrecht, Graduate Student, MIT Media Lab • Elisa Kallioniemi, Assistant Professor, New Jersey Institute of Technology • Max Kanwal, PhD Student, Stanford University • Sven Truckenbrodt, Group Leader, MRC Laboratory of Molecular Biology Secure AI • Huixin Zhan, Assistant Professor, New Mexico Tech • Keith Patarroyo, Research Fellow, University of Glasgow Keith Patarroyo • Mateo Petel, Research Scientist, Stanford University • Tianyi Alex Qiu, Research Fellow, Oxford Human-Centered AI Lab Tianyi Alex Qiu • Vivek Nair, CEO, Multifactor Nanotechnology • Alberto Privitera, Assistant Professor, University of Florence • Kathryn Shelley, Postdoctoral Researcher, University of Washington • Konlin Shen, Research and Development Engineer, University of California San Francisco • Qiancheng Xiong, Senior Scientist, A*STAR Bioprocessing Technology Institute Space • Philip Linden, Space Systems Engineer, Planet Labs PBC • Sidh Sikka, Co-Founder, Manifold Research Sidh Sikka Existential Hope • Abigail Olvera, Research Director, Golden Gate Institute for AI Abi Olvera • Fin Moorhouse, Researcher, Forethought Fin Moorhouse • Mahlaqua Mila Noor, Viral Immunologist, University of Cambridge • Ninon Lizé Masclef, Research Affiliate, MIT Media Lab Ninon Lizé Masclef • Peggy Yin, PhD Student, Stanford University • Ruairidh Battleday, AI Researchers & Founder, Thinking About Thinking Ruairidh Battleday Learn more about our Fellowship:
0:29

Announcing our 2026 Fellows! One is a neuroscientist exploring how the brain computes at a molecular level, another is a bioengineer 3D-printing human tissue. There’s a PhD student working on computational protein design, and an engineer developing robots to build large structures in space – just to name a few of the badasses in our new Fellowship cohort! With this one-year program, we want to support early-career talents advancing important science and tech. We connect them with senior scientists, invite them to our technical workshops, seminars, and Vision Weekends alongside leaders in their fields, and offer platforms for sharing their work. We are incredibly excited to introduce our 2026 Fellows! Longevity Biotechnology • Alex Plesa, Scientist, Harvard University Alex Plesa • Donnacha Fitzgerald, Founder, Origenity Donnacha Fitzgerald • Gianluca Cidonio, Assistant Professor, Sapienza University Gianluca Cidonio • Jakub Lála, PhD Student, Imperial College London Jakub Lála 👨🏻‍🍳🥯 • Léo Lopez, Staff Scientist, Tufts University • Nick Schaum, Postdoc & Co-Founder, University of Cambridge & Neurotechnology • Avery Krieger, Founder & CEO, Constellation Systems Avery Krieger • Constanze Albrecht, Graduate Student, MIT Media Lab • Elisa Kallioniemi, Assistant Professor, New Jersey Institute of Technology • Max Kanwal, PhD Student, Stanford University • Sven Truckenbrodt, Group Leader, MRC Laboratory of Molecular Biology Secure AI • Huixin Zhan, Assistant Professor, New Mexico Tech • Keith Patarroyo, Research Fellow, University of Glasgow Keith Patarroyo • Mateo Petel, Research Scientist, Stanford University • Tianyi Alex Qiu, Research Fellow, Oxford Human-Centered AI Lab Tianyi Alex Qiu • Vivek Nair, CEO, Multifactor Nanotechnology • Alberto Privitera, Assistant Professor, University of Florence • Kathryn Shelley, Postdoctoral Researcher, University of Washington • Konlin Shen, Research and Development Engineer, University of California San Francisco • Qiancheng Xiong, Senior Scientist, A*STAR Bioprocessing Technology Institute Space • Philip Linden, Space Systems Engineer, Planet Labs PBC • Sidh Sikka, Co-Founder, Manifold Research Sidh Sikka Existential Hope • Abigail Olvera, Research Director, Golden Gate Institute for AI Abi Olvera • Fin Moorhouse, Researcher, Forethought Fin Moorhouse • Mahlaqua Mila Noor, Viral Immunologist, University of Cambridge • Ninon Lizé Masclef, Research Affiliate, MIT Media Lab Ninon Lizé Masclef • Peggy Yin, PhD Student, Stanford University • Ruairidh Battleday, AI Researchers & Founder, Thinking About Thinking Ruairidh Battleday Learn more about our Fellowship:

Foresight Institute

10,281 görüntüleme • 6 ay önce

WATCH: What does this focus group of voters think about Burnham, Reform, Restore? Why do they feel let down by Lab & can Burnham win a place that turned Reform in the local elections back? Luke Tryl asks the Qs Big team effort: Josh Gafson producing & Finn Lehane leading the 🎥
4:45

WATCH: What does this focus group of voters think about Burnham, Reform, Restore? Why do they feel let down by Lab & can Burnham win a place that turned Reform in the local elections back? Luke Tryl asks the Qs Big team effort: Josh Gafson producing & Finn Lehane leading the 🎥

Beth Rigby

58,291 görüntüleme • 1 ay önce