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Evolution can't even create one single novel protein fold. Why should anyone accept the story that evolution built entire complex systems of nano-machines built with thousands of unique proteins?

Divinely Designed

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This fact absolutely shatters evolution. ...And makes the intelligent design in Life certain. All the systems in Life that make things function - like everything that enables birds to fly - require a whole set of complex interconnected parts. Nothing works in isolation. Something evolutionists overlook is how the nature of all these systems are intricately interconnected. Every part relies on something else to make it work. You need the whole system, down to the DNA itself, or the function fails. This coordinattion between so many systems makes step-by-step evolution all but impossible. For instance... A wing isn’t just bones and feathers (or membrane). A wing requires a certain type of hollow bones, which the alleged ancestors of birds didn't have. And wings by themselves are useless - what reproductive benefit would wings have without the accompanying systems that lead to actual flight (the simultaneous requirements for bone pneumatization, muscle attachment sites, feather or membrane development, and the regulatory changes that control all of them)? Wings without these features would be harmful. Hollow bones without flight would be detrimental. The step-by-step path leading from non-bird to flying birds is filled with easily killed, unselectable intermediates. This is where evolutionists constantly fail - they look at modification in isolation, without considering that these systems are large, interconnected networks of functional parts all working together. And it all starts at the genetic level, from the DNA itself. DNA genes code for proteins. Regulatory information organizes when these proteins are built and how much should be made. Further regulatory systems coordinate where these proteins go after they’re built. And yet more informational networks place the proteins into the final system in coordination with other proteins. Then these protein systems are fit together to make entire organs, tissues, bones, etc. All of these systems and processes are coordinated from the DNA - which means major modification like turning a fish fin into a bird wing requires many coordinated DNA changes across the entire network. One change at a time simply cannot lead to the coordination of an entire multi-part coordinated system like this. A mutation that changes one protein would need another coordinated mutation to fit that mutated protein into the right place, which would require other proteins to be mutated to fit together into that system, which would also require yet more regulatory mutations to keep everything coordinated... Nothing works in isolation. It's all connected. Which is why it can't evolve one step at a time. One step at a time does nothing. Life requires all or nothing systems. Only intelligence can engineer all or nothing systems.

This fact absolutely shatters evolution. ...And makes the intelligent design in Life certain. All the systems in Life that make things function - like everything that enables birds to fly - require a whole set of complex interconnected parts. Nothing works in isolation. Something evolutionists overlook is how the nature of all these systems are intricately interconnected. Every part relies on something else to make it work. You need the whole system, down to the DNA itself, or the function fails. This coordinattion between so many systems makes step-by-step evolution all but impossible. For instance... A wing isn’t just bones and feathers (or membrane). A wing requires a certain type of hollow bones, which the alleged ancestors of birds didn't have. And wings by themselves are useless - what reproductive benefit would wings have without the accompanying systems that lead to actual flight (the simultaneous requirements for bone pneumatization, muscle attachment sites, feather or membrane development, and the regulatory changes that control all of them)? Wings without these features would be harmful. Hollow bones without flight would be detrimental. The step-by-step path leading from non-bird to flying birds is filled with easily killed, unselectable intermediates. This is where evolutionists constantly fail - they look at modification in isolation, without considering that these systems are large, interconnected networks of functional parts all working together. And it all starts at the genetic level, from the DNA itself. DNA genes code for proteins. Regulatory information organizes when these proteins are built and how much should be made. Further regulatory systems coordinate where these proteins go after they’re built. And yet more informational networks place the proteins into the final system in coordination with other proteins. Then these protein systems are fit together to make entire organs, tissues, bones, etc. All of these systems and processes are coordinated from the DNA - which means major modification like turning a fish fin into a bird wing requires many coordinated DNA changes across the entire network. One change at a time simply cannot lead to the coordination of an entire multi-part coordinated system like this. A mutation that changes one protein would need another coordinated mutation to fit that mutated protein into the right place, which would require other proteins to be mutated to fit together into that system, which would also require yet more regulatory mutations to keep everything coordinated... Nothing works in isolation. It's all connected. Which is why it can't evolve one step at a time. One step at a time does nothing. Life requires all or nothing systems. Only intelligence can engineer all or nothing systems.

Divinely Designed

47,292 Aufrufe • vor 1 Monat

The most detailed 3D reconstruction of a cell ever created. Blows my mind every time. But what exactly are we looking at here? The average human cell contains: ~ 15-20 total distinct organelle types, totalling between ~1-10 million working together per cell. All these nano-machines in the cell are made up of proteins. ~ 8,000-10,000 distinct types of unique proteins, adding up to between 40 million - 10 trillion total proteins making up all those cellular systems. ~ 10,000 - 15,000 distinct types of RNA shuttling information around the cell, totalling up to ~10 million RNA molecules moving around the cell simultaneously. ~ Billions of Lipid molecules packed together into the cell membrane, which is also packed tightly with millions more protein-based nano-machines. And let's not forget billions of lines of DNA information to build and run it all. That's TRILLIONS of of individual molecular pieces working together to make a single cell function. That means there is more complexity in a single cell than humanity's largest cities. And people still believe this wasn't Divinely Designed. This is God's Glory on Display. But to make the point. A cell couldn't have evolved from some nebulous simpler "protocell" because even the simplest cells still require massive complexity. The "simplest" cell ever created was engineered by scientists knocking out pieces of a functional cell until it stopped functioning. Here is what they found is the absolute necessary minimal requirements of a cell to function: - Over ~531,000 lines of coded DNA information - 473 total genes to create hundreds of unique protein products (they later added 19 genes back in because the cell was so weak) - Hundreds of thousands of total proteins all working together - Extensive regulatory networks guiding all these interactions If the cell doesn't have all these systems in place, from the start... it doesn't live. Cell rely on an intricate network of complex systems, which are themselves built from complex interconnected pieces woven together into an incomprehensibly complex web of functionilty. Only intelligence has ever been observed creation vast interconnected systems like this. Life was clearly Created. It couldn't happen any other way.

The most detailed 3D reconstruction of a cell ever created. Blows my mind every time. But what exactly are we looking at here? The average human cell contains: ~ 15-20 total distinct organelle types, totalling between ~1-10 million working together per cell. All these nano-machines in the cell are made up of proteins. ~ 8,000-10,000 distinct types of unique proteins, adding up to between 40 million - 10 trillion total proteins making up all those cellular systems. ~ 10,000 - 15,000 distinct types of RNA shuttling information around the cell, totalling up to ~10 million RNA molecules moving around the cell simultaneously. ~ Billions of Lipid molecules packed together into the cell membrane, which is also packed tightly with millions more protein-based nano-machines. And let's not forget billions of lines of DNA information to build and run it all. That's TRILLIONS of of individual molecular pieces working together to make a single cell function. That means there is more complexity in a single cell than humanity's largest cities. And people still believe this wasn't Divinely Designed. This is God's Glory on Display. But to make the point. A cell couldn't have evolved from some nebulous simpler "protocell" because even the simplest cells still require massive complexity. The "simplest" cell ever created was engineered by scientists knocking out pieces of a functional cell until it stopped functioning. Here is what they found is the absolute necessary minimal requirements of a cell to function: - Over ~531,000 lines of coded DNA information - 473 total genes to create hundreds of unique protein products (they later added 19 genes back in because the cell was so weak) - Hundreds of thousands of total proteins all working together - Extensive regulatory networks guiding all these interactions If the cell doesn't have all these systems in place, from the start... it doesn't live. Cell rely on an intricate network of complex systems, which are themselves built from complex interconnected pieces woven together into an incomprehensibly complex web of functionilty. Only intelligence has ever been observed creation vast interconnected systems like this. Life was clearly Created. It couldn't happen any other way.

Divinely Designed

168,913 Aufrufe • vor 4 Monaten

a Vietnamese AI engineer just built a real-time system that counts objects moving down a conveyor belt. it runs on ultralytics' objectcounter. train a detector, define the region you care about, and it handles the rest. works for anything on a line, parts, packages, produce. the clever bit: instead of hand-labeling thousands of frames, he took a single frame, pre-annotated it with meta's segment anything (sam-2, built into ultralytics), and trained yolo11-nano on just that. one annotated frame, and it tracks objects accurately across the entire video.

a Vietnamese AI engineer just built a real-time system that counts objects moving down a conveyor belt. it runs on ultralytics' objectcounter. train a detector, define the region you care about, and it handles the rest. works for anything on a line, parts, packages, produce. the clever bit: instead of hand-labeling thousands of frames, he took a single frame, pre-annotated it with meta's segment anything (sam-2, built into ultralytics), and trained yolo11-nano on just that. one annotated frame, and it tracks objects accurately across the entire video.

Oliver Prompts

29,786 Aufrufe • vor 2 Monaten

The elites built large doomsday bunkers at higher elevations, like the Cheyenne Mountain Complex, an impenetrable doomsday city built at 9,565 feet (2,916 meters), with the hope that the 2-mile-high waves would not reach it. This is also the reason why so many doomsday bunkers were built high in the Alps. China also has a massive complex built at a higher elevation that could house more than 1 million members of its elite.

The elites built large doomsday bunkers at higher elevations, like the Cheyenne Mountain Complex, an impenetrable doomsday city built at 9,565 feet (2,916 meters), with the hope that the 2-mile-high waves would not reach it. This is also the reason why so many doomsday bunkers were built high in the Alps. China also has a massive complex built at a higher elevation that could house more than 1 million members of its elite.

Open Minded Approach

98,826 Aufrufe • vor 5 Monaten

🥳 Happy #DNADay! 🧬 What better way to celebrate than with cycleHCR: one of our newest tools, developed by the Liu Lab, that uses a novel DNA barcode system to track hundreds of RNA & protein molecules in single cells within thick biological samples ➡️

🥳 Happy #DNADay! 🧬 What better way to celebrate than with cycleHCR: one of our newest tools, developed by the Liu Lab, that uses a novel DNA barcode system to track hundreds of RNA & protein molecules in single cells within thick biological samples ➡️

HHMI | Janelia

25,244 Aufrufe • vor 1 Jahr

Many drugs work by binding to a specific target in the body and blocking or changing what it does. An important first step in the drug development process is designing a molecule that can bind tightly to its target. Traditionally, that's meant weeks or months of expert work per target, sifting through a large number of candidates to identify the few that work. We wanted to test if Claude could successfully design novel protein binders from scratch (also called de novo design). With a protein design prompt written by a human expert, Claude autonomously designed protein binders against 14 out of 15 targets. We then worked with Adaptyv Bio and Twist Bioscience, who independently built and tested the proteins Claude designed.

Many drugs work by binding to a specific target in the body and blocking or changing what it does. An important first step in the drug development process is designing a molecule that can bind tightly to its target. Traditionally, that's meant weeks or months of expert work per target, sifting through a large number of candidates to identify the few that work. We wanted to test if Claude could successfully design novel protein binders from scratch (also called de novo design). With a protein design prompt written by a human expert, Claude autonomously designed protein binders against 14 out of 15 targets. We then worked with Adaptyv Bio and Twist Bioscience, who independently built and tested the proteins Claude designed.

Anthropic

4,339,495 Aufrufe • vor 1 Monat

Germany’s Terrifyingly Massive WW2 Siege Monster 🔥💥 During World War II, Germany built the Karl-Gerät, one of the largest and most terrifying siege weapons ever created. Weighing a massive 127 tons, this enormous self-propelled mortar fired 600mm shells capable of destroying entire buildings and fortified positions with a single shot. Only seven of these monsters were ever built due to their size and complexity.

Germany’s Terrifyingly Massive WW2 Siege Monster 🔥💥 During World War II, Germany built the Karl-Gerät, one of the largest and most terrifying siege weapons ever created. Weighing a massive 127 tons, this enormous self-propelled mortar fired 600mm shells capable of destroying entire buildings and fortified positions with a single shot. Only seven of these monsters were ever built due to their size and complexity.

Deadly Weapons

172,302 Aufrufe • vor 3 Monaten

Everything Michio Kushi said in 1983 is becoming a reality, especially with Neuralink and Starlink. One will integrate humans with machines, while Starlink will provide this new species of humans with virtually unlimited bandwidth. That is why they want the entire sky to be filled with these satellites. This will create powerful elites and easily controllable servants.

Everything Michio Kushi said in 1983 is becoming a reality, especially with Neuralink and Starlink. One will integrate humans with machines, while Starlink will provide this new species of humans with virtually unlimited bandwidth. That is why they want the entire sky to be filled with these satellites. This will create powerful elites and easily controllable servants.

Open Minded Approach

37,643 Aufrufe • vor 2 Monaten

Which one evolved first? Male or female? Evolution: "They just co-evolved gradually somehow." Ya....ok. Biological sex is proof that Life is created. Two coordinated systems with entirely different anatomy. Neither functions without the other. Without both, Life ends. So which half evolved first? How many bajillions of years did that half have to wait around for the second half to get the right mutations? Evolution cannot explain male & female. Because Life was Created: "Male and female God created them."

Which one evolved first? Male or female? Evolution: "They just co-evolved gradually somehow." Ya....ok. Biological sex is proof that Life is created. Two coordinated systems with entirely different anatomy. Neither functions without the other. Without both, Life ends. So which half evolved first? How many bajillions of years did that half have to wait around for the second half to get the right mutations? Evolution cannot explain male & female. Because Life was Created: "Male and female God created them."

Divinely Designed

27,829 Aufrufe • vor 4 Monaten

If you’ve ever wondered what confidence a civilization can have at its peak, look at those walls. A thousand years ago, in the forests of central India, a small Chandela kingdom built a temple complex so advanced in geometry, astronomy, and stone engineering that modern architects still struggle to explain parts of it. No steel. No machines. Just craftsmen who carved sandstone like it was butter and encoded an entire worldview into a city of temples. This is the Khujaraho Temple Complex, a group of Hindu and Jain temples in Madhya Pradesh, India.

If you’ve ever wondered what confidence a civilization can have at its peak, look at those walls. A thousand years ago, in the forests of central India, a small Chandela kingdom built a temple complex so advanced in geometry, astronomy, and stone engineering that modern architects still struggle to explain parts of it. No steel. No machines. Just craftsmen who carved sandstone like it was butter and encoded an entire worldview into a city of temples. This is the Khujaraho Temple Complex, a group of Hindu and Jain temples in Madhya Pradesh, India.

Culture Explorer

107,725 Aufrufe • vor 10 Monaten

The IDF has announced that it is ready to destroy the entire Ali Taher Ridge tunnel complex built by Hezbollah and Iran in the next few days. They’ve cleared all terrorists with none remaining alive and will detonate significant amounts of explosives to take the entire complex down. Iran warned us if we did, so we’re going to do it anyway. The main beneficiary of this complex being destroyed will ultimately be Lebanon and the decent Lebanese people. Hezbollah will feel this most. It’s going to be beautiful to watch.

The IDF has announced that it is ready to destroy the entire Ali Taher Ridge tunnel complex built by Hezbollah and Iran in the next few days. They’ve cleared all terrorists with none remaining alive and will detonate significant amounts of explosives to take the entire complex down. Iran warned us if we did, so we’re going to do it anyway. The main beneficiary of this complex being destroyed will ultimately be Lebanon and the decent Lebanese people. Hezbollah will feel this most. It’s going to be beautiful to watch.

Mor Edge Insight

295,602 Aufrufe • vor 1 Monat

The internet gave us infrastructure to connect, communicate, and transact. But more and more of what we need to do together now involves information that cannot simply be shared. Digital voting should produce a public, verifiable result without exposing individual choices. Healthcare researchers should be able to learn from sensitive patient data without exposing the people behind it. Competitors should be able to solve shared problems without giving up the information that keeps them competitive. Interfold is building infrastructure for that problem: confidential coordination. It lets independent parties compute together across private inputs without exposing them or relying on trusted hardware. Decryption is distributed across independent operators, and anyone can verify the result. That opens the door to digital democratic systems with secret ballots, markets built around private positions, and entirely new forms of collective intelligence. Systems increasingly bring together people, institutions, and agentic systems with different interests and incentives. The internet needs a new coordination model built for that reality.

The internet gave us infrastructure to connect, communicate, and transact. But more and more of what we need to do together now involves information that cannot simply be shared. Digital voting should produce a public, verifiable result without exposing individual choices. Healthcare researchers should be able to learn from sensitive patient data without exposing the people behind it. Competitors should be able to solve shared problems without giving up the information that keeps them competitive. Interfold is building infrastructure for that problem: confidential coordination. It lets independent parties compute together across private inputs without exposing them or relying on trusted hardware. Decryption is distributed across independent operators, and anyone can verify the result. That opens the door to digital democratic systems with secret ballots, markets built around private positions, and entirely new forms of collective intelligence. Systems increasingly bring together people, institutions, and agentic systems with different interests and incentives. The internet needs a new coordination model built for that reality.

The Interfold

17,702 Aufrufe • vor 1 Monat

Stripe’s homepage has 637 KB of HTML for 539 words. Humans read it for free, but a bot needs $0.26 to read the same words, because it wades 87,400 tokens of markup, if it even gets there. With this in mind, I built a lens that shows you any webpage the way machines see them

Stripe’s homepage has 637 KB of HTML for 539 words. Humans read it for free, but a bot needs $0.26 to read the same words, because it wades 87,400 tokens of markup, if it even gets there. With this in mind, I built a lens that shows you any webpage the way machines see them

aadharsh

19,035 Aufrufe • vor 1 Monat

🚨 AMERICA JUST BUILT THE WORLD’S MOST POWERFUL METAL 3D PRINTER AND IT’S ABOUT TO MASS-PRODUCE ROCKETS AND MISSILES. Divergent Technologies has unveiled the Monolith One, a giant industrial metal printer standing over 8 meters tall and armed with 12 high-powered lasers delivering a combined 24 kilowatts of energy. Unlike typical 3D printers used for prototypes, this machine is built for serious, high-volume production. It can print large, complex aerospace and defense parts in aluminum, titanium, steel, and nickel alloys and it roughly doubles the output of current systems. Why this matters: • Divergent plans to install 64 more of these machines in a massive new 430,000 sq ft factory in Long Beach, California • Once running, the facility aims to produce tens of thousands of munition airframes per year plus hundreds of thousands of critical metal components • It slashes manufacturing time from months down to weeks or even days • The company already supplies major players like Lockheed Martin and RTX The deeper implication: This isn’t just another 3D printer. It represents a shift toward software-defined, on-demand manufacturing at industrial scale for mission-critical hardware. As defense and aerospace demand skyrockets, traditional supply chains are too slow. Systems like Monolith One could become a cornerstone of faster, more resilient domestic production especially for complex structures that are difficult or impossible to make conventionally. We’re watching the industrialization of additive manufacturing in real time. How do you think large-scale 3D printing will change aerospace and defense manufacturing over the next decade? Follow for more frontier manufacturing and defense technology.

🚨 AMERICA JUST BUILT THE WORLD’S MOST POWERFUL METAL 3D PRINTER AND IT’S ABOUT TO MASS-PRODUCE ROCKETS AND MISSILES. Divergent Technologies has unveiled the Monolith One, a giant industrial metal printer standing over 8 meters tall and armed with 12 high-powered lasers delivering a combined 24 kilowatts of energy. Unlike typical 3D printers used for prototypes, this machine is built for serious, high-volume production. It can print large, complex aerospace and defense parts in aluminum, titanium, steel, and nickel alloys and it roughly doubles the output of current systems. Why this matters: • Divergent plans to install 64 more of these machines in a massive new 430,000 sq ft factory in Long Beach, California • Once running, the facility aims to produce tens of thousands of munition airframes per year plus hundreds of thousands of critical metal components • It slashes manufacturing time from months down to weeks or even days • The company already supplies major players like Lockheed Martin and RTX The deeper implication: This isn’t just another 3D printer. It represents a shift toward software-defined, on-demand manufacturing at industrial scale for mission-critical hardware. As defense and aerospace demand skyrockets, traditional supply chains are too slow. Systems like Monolith One could become a cornerstone of faster, more resilient domestic production especially for complex structures that are difficult or impossible to make conventionally. We’re watching the industrialization of additive manufacturing in real time. How do you think large-scale 3D printing will change aerospace and defense manufacturing over the next decade? Follow for more frontier manufacturing and defense technology.

TheNewPhysics

80,575 Aufrufe • vor 3 Monaten

Göbekli Tepe was built when the Sahara and the entire regions of Turkey, the Levant, and the Arabian Peninsula were not deserts. In fact, it was constructed around 3,000 years before these regions turned into deserts during the 5.9 kiloyear event, the Solovki Geomagnetic Excursion, and the Y-chromosome bottleneck, when 19 out of 20 male lineages went extinct. This event was Noah’s Flood coupled with rapid climate change. In my opinion, the pyramids were built when the Sahara was green. Mainstream science hates this idea because it reveals deeper questions about religion, what it means to be human, evolution, and the cyclical event.

Göbekli Tepe was built when the Sahara and the entire regions of Turkey, the Levant, and the Arabian Peninsula were not deserts. In fact, it was constructed around 3,000 years before these regions turned into deserts during the 5.9 kiloyear event, the Solovki Geomagnetic Excursion, and the Y-chromosome bottleneck, when 19 out of 20 male lineages went extinct. This event was Noah’s Flood coupled with rapid climate change. In my opinion, the pyramids were built when the Sahara was green. Mainstream science hates this idea because it reveals deeper questions about religion, what it means to be human, evolution, and the cyclical event.

Open Minded Approach

267,191 Aufrufe • vor 4 Monaten