正在加载视频...

视频加载失败

返回首页

Excited to share our work showing how the Integrator complex terminates RNA polymerase II (Pol II) transcription i.e. removal of Pol II from the DNA template Published in nature Many thanks to my mentor Patrick Cramer Patrick Cramer for unwavering support

isaac_fianu's profile picture

Isaac Fianu

1,025 subscribers

38,501 次观看 • 2 年前 •via X (Twitter)

教育健康养生科学技术
LIVE

Anya Rossi• Live Now

Private livecam show

10 条评论

Isaac Fianu 的头像
Isaac Fianu2 年前

Cheers to the team: @sciJamesWalshe, @MoritzOchmann, @neos_cruz, Olexandr Dybkov, Henning Urlaub and @mpgpresident. Thanks to the editor @JieWangJW and the reviewers for constructive feedback

Abrar Aljahani 的头像
Abrar Aljahani2 年前

@Nature @mpgpresident Fantastic work! Congratulations Isaac 🥳

Arjun Bhatta 的头像
Arjun Bhatta2 年前

@Nature @mpgpresident Many congratulations Isaac! 🎊🎊🎊

Hauke Hillen 的头像
Hauke Hillen2 年前

@Nature @mpgpresident Great stuff, congratulations @isaac_fianu et. al!

Carmelo Ferrai 的头像
Carmelo Ferrai2 年前

@Nature @mpgpresident 👏🏽

Christopher Thomas 的头像
Christopher Thomas2 年前

@Nature @mpgpresident Congratulations Isaac! 🙌🏼

Shalini Pradhan 的头像
Shalini Pradhan2 年前

@Nature @mpgpresident Congratulations @isaac_fianu and team. Amazing work 👏👏

Goran Kokic 的头像
Goran Kokic2 年前

@Nature @mpgpresident Very impressive, Isaac! Stunning structure 🤩 🥳

Svetlana Dodonova 的头像
Svetlana Dodonova2 年前

@Nature @mpgpresident Congratulations!! Amazing work!!

Wojciech (Wojtek) Kopec 的头像
Wojciech (Wojtek) Kopec2 年前

@Nature @mpgpresident Wonderful 🥳🥳🥳

相关视频

🔬🧬 Excited to share our latest study Science Magazine developing ChromExM which uses expansion microscopy to visualize the chromatin, transcription, RNA POL II and pioneer factor Nanog during genome activation.
0:45

🔬🧬 Excited to share our latest study Science Magazine developing ChromExM which uses expansion microscopy to visualize the chromatin, transcription, RNA POL II and pioneer factor Nanog during genome activation.

Giraldez Lab

136,245 次观看 • 3 年前

Excited to share our new preprint on co-transcriptional splicing! U1 snRNP is recruited to RNA polymerase II through multiple interaction sites, with elongation factor SPT6 binding directly to the U1 snRNP protein. #cryoEM #transcription #splicing
0:21

Excited to share our new preprint on co-transcriptional splicing! U1 snRNP is recruited to RNA polymerase II through multiple interaction sites, with elongation factor SPT6 binding directly to the U1 snRNP protein. #cryoEM #transcription #splicing

Suyang Zhang

10,449 次观看 • 1 年前

Water is 70–80% of a cell, with our mspSA + SGAG affinity grid, we capture a near atomic (<2 Å) view showing water actively driving gene transcription inside RNA Pol II. Not just background,water is part of the machinery. Now published in Molecular Cell.
1:44

Water is 70–80% of a cell, with our mspSA + SGAG affinity grid, we capture a near atomic (<2 Å) view showing water actively driving gene transcription inside RNA Pol II. Not just background,water is part of the machinery. Now published in Molecular Cell.

the Peijun Zhang Lab

10,289 次观看 • 3 个月前

.Patrick Mahomes II and Brittany Mahomes are back in OKC for the second straight year to support Texas Tech Softball! 👋 #WCWS x 📺 ESPN
0:25

.Patrick Mahomes II and Brittany Mahomes are back in OKC for the second straight year to support Texas Tech Softball! 👋 #WCWS x 📺 ESPN

Texas Tech Red Raiders

277,041 次观看 • 1 个月前

How is this my job HOW (Playing with transparencies in the book Vasarely II, from 1973, which I just bought thanks to a tip from @reas)
1:17

How is this my job HOW (Playing with transparencies in the book Vasarely II, from 1973, which I just bought thanks to a tip from @reas)

Tina Rivers Ryan

22,643 次观看 • 3 年前

Our new findings on how the ribosome couples with the RNA polymerase are summarized in a movie highlighting the dynamics of the process🎞️🎥 Thanks to Clemens Bretscher for the great animations! - EMBL paper in bioRxiv
2:00

Our new findings on how the ribosome couples with the RNA polymerase are summarized in a movie highlighting the dynamics of the process🎞️🎥 Thanks to Clemens Bretscher for the great animations! - EMBL paper in bioRxiv

Olivier Duss

138,881 次观看 • 2 年前

Another collection of neat, rarely seen moments from the Northwoods of Minnesota! I.e., this is “Part II” of the highlights from our ~350 cameras deployed in the field last summer. Check out our last post for Part 1! Will be curious to hear what folks think is the best clip…the red foxes? the lynx? the bobcat? Either way, big thanks to the Minnesota Environment and Natural Resources Trust Fund for supporting our work, which allows us to share these gems with everyone for free!
2:20

Another collection of neat, rarely seen moments from the Northwoods of Minnesota! I.e., this is “Part II” of the highlights from our ~350 cameras deployed in the field last summer. Check out our last post for Part 1! Will be curious to hear what folks think is the best clip…the red foxes? the lynx? the bobcat? Either way, big thanks to the Minnesota Environment and Natural Resources Trust Fund for supporting our work, which allows us to share these gems with everyone for free!

Voyageurs Wolf Project

12,561 次观看 • 1 年前

WATCH: Here is the emotional goodbye video from DaRon Holmes II DaRon Holmes II & Dayton 6th on instagram following his decision to officialy stay in the NBA Draft. “Thank you for everything.” Holmes II gives a heart-felt thanks to all of #Flyers nation. Class act. 👏🏼 WDTN
2:14

WATCH: Here is the emotional goodbye video from DaRon Holmes II DaRon Holmes II & Dayton 6th on instagram following his decision to officialy stay in the NBA Draft. “Thank you for everything.” Holmes II gives a heart-felt thanks to all of #Flyers nation. Class act. 👏🏼 WDTN

Joey DeBerardino

24,583 次观看 • 2 年前

It takes a dedicated team to send a rocket around the Moon! In the latest episode of our Curious Universe podcast, hear from a few of the many ground support crew members behind Artemis II:
0:36

It takes a dedicated team to send a rocket around the Moon! In the latest episode of our Curious Universe podcast, hear from a few of the many ground support crew members behind Artemis II:

NASA

562,645 次观看 • 5 个月前

How can the Global South work together to address the profound and complex changes shaping the world today, and contribute to the building of a community with a shared future for mankind? Discover the insightful views from speakers at sub-forum II.
7:26

How can the Global South work together to address the profound and complex changes shaping the world today, and contribute to the building of a community with a shared future for mankind? Discover the insightful views from speakers at sub-forum II.

Hua Chunying 华春莹

71,119 次观看 • 2 年前

Thanks to our NASA Artemis II astronauts for working on the weekend! The fourth day of their mission brought more crew preparations for Monday's trip around the Moon and stunning new images from their vantage point. What views are you most excited to see?
0:49

Thanks to our NASA Artemis II astronauts for working on the weekend! The fourth day of their mission brought more crew preparations for Monday's trip around the Moon and stunning new images from their vantage point. What views are you most excited to see?

NASA

1,371,135 次观看 • 3 个月前

VIDEO: The people of Rukiga and Kabale have spoken! Despite the police trying to interfere, NUP’s support goes far beyond Buganda. Thanks to NTV and Patrick for showing how Kigezi stands united behind our leader, calling for a New Uganda. #ANewUgandaNow
7:37

VIDEO: The people of Rukiga and Kabale have spoken! Despite the police trying to interfere, NUP’s support goes far beyond Buganda. Thanks to NTV and Patrick for showing how Kigezi stands united behind our leader, calling for a New Uganda. #ANewUgandaNow

SSEKABIRA PATRICK

14,232 次观看 • 8 个月前

We’re so excited to share our trailer for Hades II!! Our first collaboration with Supergiant Games was one we’ll always hold dear to our hearts and it certainly created huge hype around the studio, being massive fans of the game.
1:30

We’re so excited to share our trailer for Hades II!! Our first collaboration with Supergiant Games was one we’ll always hold dear to our hearts and it certainly created huge hype around the studio, being massive fans of the game.

THE LINE

266,605 次观看 • 10 个月前

This is so unbelievably special. Over the years, Patrick Mahomes II has made a point to film commercials in KC to continue to support his city and create jobs for the industry. The amazing KC Film community put together this video to thank him! ❤️
1:39

This is so unbelievably special. Over the years, Patrick Mahomes II has made a point to film commercials in KC to continue to support his city and create jobs for the industry. The amazing KC Film community put together this video to thank him! ❤️

Jacquelyn Dahl

2,500,206 次观看 • 2 年前

The 6th Annual 15 and the Mahomies Foundation Gala! Over 900 incredible supporters in attendance and $1,508,000 granted to 27 Kansas City charities up on stage. Thank you to all of our amazing partners who continue to support the mission. Together, we are changing lives. See you all next year! ❤️ Patrick Mahomes II
0:59

The 6th Annual 15 and the Mahomies Foundation Gala! Over 900 incredible supporters in attendance and $1,508,000 granted to 27 Kansas City charities up on stage. Thank you to all of our amazing partners who continue to support the mission. Together, we are changing lives. See you all next year! ❤️ Patrick Mahomes II

15 and the Mahomies

398,523 次观看 • 9 个月前

Beginning this year’s “Veteran of the Month” series with the incredible story of Colonel Patrick Downing from Mobile. From helping establish a veterans cemetery in Spanish Fort to bringing more than 1,000 World War II veterans to D.C. through Honor Flight South Alabama, Alabama is grateful for Pat’s service to our state. Pleased to recognize him as the January “Veteran of the Month.”
4:51

Beginning this year’s “Veteran of the Month” series with the incredible story of Colonel Patrick Downing from Mobile. From helping establish a veterans cemetery in Spanish Fort to bringing more than 1,000 World War II veterans to D.C. through Honor Flight South Alabama, Alabama is grateful for Pat’s service to our state. Pleased to recognize him as the January “Veteran of the Month.”

Coach Tommy Tuberville

19,999 次观看 • 6 个月前

"That is remarkable by Patrick... that he set the goals that high and exceeded all of them" Patrick Mahomes II hit every single one of the goals he expressed to nick wright in his pre-draft interview 8 years ago *Yes, that's really how Nick looked before he grew his hair out
3:45

"That is remarkable by Patrick... that he set the goals that high and exceeded all of them" Patrick Mahomes II hit every single one of the goals he expressed to nick wright in his pre-draft interview 8 years ago *Yes, that's really how Nick looked before he grew his hair out

What’s Wright? with Nick Wright

186,106 次观看 • 1 年前

After a bipartisan effort to legalize sports betting last year, I cast Kansas’ first sports bet on the Kansas City Chiefs to win the Super Bowl. It turns out the Chiefs are always a good bet. Now, I’ll donate my winnings to Patrick Mahomes II’ 15 and the Mahomies to support their work across KC.
1:17

After a bipartisan effort to legalize sports betting last year, I cast Kansas’ first sports bet on the Kansas City Chiefs to win the Super Bowl. It turns out the Chiefs are always a good bet. Now, I’ll donate my winnings to Patrick Mahomes II’ 15 and the Mahomies to support their work across KC.

Governor Laura Kelly

239,760 次观看 • 3 年前

We’re excited to share our latest work published today in Nature Biotechnology: Protein2PAM, an AI model that enables the rapid design of CRISPR editors with new PAM recognition And we’re making the model freely available for research and commercial use:
1:16

We’re excited to share our latest work published today in Nature Biotechnology: Protein2PAM, an AI model that enables the rapid design of CRISPR editors with new PAM recognition And we’re making the model freely available for research and commercial use:

Profluent

16,511 次观看 • 6 个月前

“I know there’s a bunch of passion, talent and grit that exists in women’s sports” 🗣️ Brittany Mahomes Our KC Current ownership group with Brittany, Patrick Mahomes II, AngieKLong & Chris Long continues to raise the bar 📈
0:33

“I know there’s a bunch of passion, talent and grit that exists in women’s sports” 🗣️ Brittany Mahomes Our KC Current ownership group with Brittany, Patrick Mahomes II, AngieKLong & Chris Long continues to raise the bar 📈

KC Current

22,619 次观看 • 1 年前