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Future "Colossal"

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Nasu ☥

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27,811 просмотров • 5 месяцев назад •via X (Twitter)

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The future is so bright, you might need to take your shades OFF for this one. De-extinction is now a reality. Meet Khaleesi—a dire wolf pup, reborn on January 31, 2025, more than 10,000 years after her species vanished. It's not #JurassicPark but this moment signals the start of a new era in biodiversity and ecological restoration. The dire wolf is back, and for Colossal, this is only the beginning.

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Congratulations to Ben Lamm and Colossal Biosciences® on announcing the successful de-extinction of the dire wolf. Wild. Two years ago, I interviewed Ben—he pushed founders to go bigger, and challenged investors to back the moonshots. It feels like the future is arriving.
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Part 2 of my Nikke carry montage from Katsucon is here! This one has my favorite intro yet 💀 Really excited for what I’ve got lined up next since I’m going to cons I’ve never been to before in the near future in ACEN and Colossal Prime #NIKKE #NIKKECosplay

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We’re Colossal Biosciences, the de-extinction company responsible for bringing back the first animals from extinction. Our dire wolf pups, Romulus and Remus, were born on October 1, 2024. Watch these pups grow up on our YouTube channel. Link in bio. These two wolves were returned from extinction using genetic edits derived from a complete dire wolf genome, meticulously reconstructed from ancient DNA found in fossils dating back 11,500 and 72,000 years. This achievement is the result of years of pioneering science, tireless innovation, and unwavering dedication. It marks a major milestone not only for our company, but for science, conservation, and humanity. With the birth of Romulus and Remus, de-extinction is no longer theory—it’s reality. There’s more work ahead, but this moment redefines what’s possible for the planet’s future.
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One of the biggest updates from my interview of george church was how even massively polygenic traits (like height, intelligence, etc) might be surprisingly malleable through germline gene editing (which is currently only tractable for a couple dozen sites). For many traits, there are apparently these single knobs which can help you access a huge range of variation. This is the strategy George's company Colossal is using to 'bring back' the wooly mammoth. There's millions of base pair differences between an elephant and a woolly mammoth. But George thinks that they can find the couple dozen gene edits necessary to bridge the actual phenotypic differences between the two species. Obviously, very interesting implications for what might be possible in the future with humans.

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