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• Google AlphaFold solved protein structure prediction • Multiple foundational AI research advances Every major breakthrough traces back to rigorous DeepMind research. When he talks AGI timelines, he's earned the right to be heard:

186,848 次观看 • 1 年前 •via X (Twitter)

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Paul William Harmon 的头像
Paul William Harmon1 年前

Sir Demis Hassabis is the most dangerous CEO alive: • Chess prodigy at age 4 • Knighted in 2023 for services to AI • Nobel Prize in Chemistry in 2024 He now leads Google's DeepMind AI His vision of the next 10 years will terrify you 🧵

Paul William Harmon 的头像
Paul William Harmon1 年前

When Hassabis makes predictions, you should listen. He co-founded DeepMind in 2010 with a bold 20-year mission to build AGI. 13 years later, they're exactly on track. His team has delivered breakthrough after breakthrough:

Paul William Harmon 的头像
Paul William Harmon1 年前

His latest prediction? AGI arrives just after 2030. That's 5-7 years from now. Sergey Brin, Google's co-founder, thinks it's even sooner - before 2030. But Hassabis has a uniquely high bar for what counts as AGI...

Paul William Harmon 的头像
Paul William Harmon1 年前

Most people think AGI means "smarter than humans." Hassabis thinks deeper. His definition: Systems that can do anything the human brain can do, even theoretically. That includes true out-of-the-box invention and flawless consistency:

Paul William Harmon 的头像
Paul William Harmon1 年前

Today's AI can solve mathematical conjectures. But it can't invent the Riemann Hypothesis. It can write code, but experts easily find trivial flaws. AGI will change that completely, and Hassabis says we're "past the middle game":

Paul William Harmon 的头像
Paul William Harmon1 年前

The job market disruption is already starting. Hassabis points to data science teams shrinking from 75 people to 1. But he's not worried about mass unemployment. Instead, he sees a fundamental shift in how we work:

Paul William Harmon 的头像
Paul William Harmon1 年前

The winners will master "meta-skills": • Learning to learn • Creativity • Adaptability Plus becoming "AI native" - using tools so well you become superhuman. But the biggest change is coming to education itself:

Paul William Harmon 的头像
Paul William Harmon1 年前

Universities might become less relevant. AI tutors will provide personalized education to anyone, anywhere. Kids growing up "AI native" will adapt faster than we can imagine. But there's a darker geopolitical reality emerging...

Paul William Harmon 的头像
Paul William Harmon1 年前

AGI is becoming the center of a new Cold War. Export controls are tightening. Countries are racing to build AI powerhouses in the Middle East. Hassabis warns: "We're all in this together" - but cooperation is getting harder.

Paul William Harmon 的头像
Paul William Harmon1 年前

The deeper question: What happens to human meaning? Hassabis predicts "radical abundance" - AI making everything incredibly cheap. Universal high income might become necessary. Some predict a religious revival as people seek purpose:

Paul William Harmon 的头像
Paul William Harmon1 年前

But some things will always be uniquely human. Human-to-human emotional connection. The soul in art that comes from real struggle and experience. Even Van Gogh's brushstrokes carry his torture - AI can't replicate that.

Paul William Harmon 的头像
Paul William Harmon1 年前

So how do you prepare for this future? Hassabis's advice for the next generation: • Don't abandon STEM fundamentals • Become an AI tool ninja now • Focus on creativity and adaptability The only certainty is massive change ahead.

Paul William Harmon 的头像
Paul William Harmon1 年前

I am Paul Harmon: • COO/President & operational strategist in tech • Leadership mentor focused on scaling high-performance teams • Champion of data-driven decision making & sustainable growth Come say hi to me on Linkedin!

Paul William Harmon 的头像
Paul William Harmon1 年前

Full Credits Below: • Hard Fork:

ksminnovation 的头像
ksminnovation1 年前

Can AI redefine scientific discovery? Dr. Tal Patalon explores OpenAI’s Deep Research in her latest Forbes article. 🎨 Future by Eduardo Kobra, provided by Eden Gallery. @TalPatalon @forbes @edengallery_

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Demis Hassabis (Demis Hassabis) has had one of the most extraordinary careers in tech. He started as a chess prodigy and video game designer at 17 before getting a PhD in neuroscience and going on to found DeepMind. His lab cracked Go, solved protein structure prediction with AlphaFold, and then gave it away free to every scientist on earth. That work won him the 2024 Nobel Prize in Chemistry. Today he leads Google DeepMind, pushing toward the same goal he set as a teenager: AGI. On this special live episode of How to Build the Future, he sat down with YC's Garry Tan to talk about what still needs to happen to get us to AGI, his advice for founders on how to stay ahead of the curve, and what the next big scientific breakthroughs might be. 01:48 — What’s Missing Before We Get To AGI? 03:36 — Why Memory Is Still Unsolved 06:14 — How AlphaGo Shaped Gemini 08:06 — Why Smaller Models Are Getting So Powerful 10:46 — The 1000x Engineer 12:40 — Continual Learning and the Future of Agents 13:32 — Why AI Still Fails at Basic Reasoning 15:33 — Are Agents Overhyped or Just Getting Started? 18:31 — Can AI Become Truly Creative? 20:26 — Open Models, Gemma, and Local AI 22:26 — Why Gemini Was Built Multimodal 24:08 — What Happens When Inference Gets Cheap? 25:24 — From AlphaFold to the Virtual Cells 28:24 — AI as the Ultimate Tool for Science 30:43 — Advice for Founders 33:30 — The AlphaFold Breakthrough Pattern 35:20 — Can AI Make Real Scientific Discoveries? 37:59 — What to Build Before AGI Arrives

Y Combinator

358,228 次观看 • 3 个月前

NEW: Harvey Co-Founder + Head of Applied Research on the *Token Reckoning* Valued at $11B, Harvey is on a mission to win the entire legal category, competing head-on against the trillion-dollar labs Coding agents hit Karpathy's "agents work now" inflection in late 2025. Harvey Co-Founder Gabe Pereyra (fmr Google Brain, DeepMind & Meta) argues legal is hitting its version of that curve right now. With both Gabe + Head of Applied Research Niko, we cover: - Open-sourcing LAB (legal agent benchmark): 1,200+ tasks across 24 practice areas, 75,000+ rubric criteria - Who's leading the leaderboard - Harvey is the largest embeddings consumer for some of the labs - Why every law firm has to be multi-model: conflict risk - The billable hour is coming back, this time for AI tokens FYI: Harvey Labs is the internal research group pushing the frontier of legal AI. Run by Niko (fmr multi-agent RL at Google Brain) & Julio Pereyra (fmr clerk + Big Law attorney), it partners with the labs, research community, & academia to bring frontier agent research into Harvey. 𝐓𝐈𝐌𝐄𝐒𝐓𝐀𝐌𝐏𝐒 (00:00) Gabe Pereyra (Co-Founder) & Niko Grupen (Head of Applied Research) (00:50) Inside Harvey's legal agent Benchmark (05:10) What happens after Benchmarking? (06:37) Why Harvey open sourced its research (09:21) Training models without client data (10:32) Google Brain vs. DeepMind (12:34) From Researcher to Founder (15:15) The Rise of the Inference Layer (18:38) The Agentic Shift (21:16) Harvey's 13 trillion tokens (23:48) AI's Biggest cost misconception (28:37) How Top AI founders learn (31:52) Learnings from Jensen Huang (34:14) How Harvey finds talent (35:41) Niko on Harvey's breakthroughs (36:38) Building a legal dataset from scratch (38:32) How to read AI Benchmarks (39:51) Niko's research playbook (40:51) The Opportunity beyond Benchmarks (41:45) Why Agent Harnesses matter (43:04) The Rise of Organizational AI

Molly O’Shea

86,280 次观看 • 1 个月前