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Google DeepMind CEO Demis Hassabis says their AlphaFold AI system has performed a billion years of PhD work and they will have their first drugs in the clinic by the end of the year, with cancer, heart disease and neurodegenerative diseases on the list of targets

888,385 görüntüleme • 1 yıl önce •via X (Twitter)

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Tsarathustra1 yıl önce

Source:

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Forget teams of doctors and high costs. NOVOS customers like Amy and Julie saw objectively better anti-aging results without breaking the bank. Effective, affordable solutions are within your reach. See how they did it:

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Best is West1 yıl önce

Talk is not action, but promising.

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It may take something like curing cancer for people to wake up! R&D AGI, that is all that is needed

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Hannibal9991 yıl önce

The rich don’t want to cure diseases. Big Pharma would lose its entire business model 😂

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In Demis We Trust

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He should be way easier to point out the the cheap generic medications and changes that are effective. To find the corruption in the medical and pharma system.

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Ali Arraour1 yıl önce

The combination of AI-powered structural biology with clinical expertise could lead to more effective, personalized treatments while significantly reducing the time and cost of drug development

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Zen Kobayashi1 yıl önce

This is mind blowing!!

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THIS MAN DOES NOT PLAY!

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Prinz Eugen, der edle Ritter1 yıl önce

Does anyone know what "drugs in the clinic" means? Clinical trials on humans? Or approved and ready to treat patients?

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Demis Hassabis, the Nobel Prize winner who runs Google DeepMind just described the most consequential project on earth, and most people have no idea it exists. The project is called Isomorphic Labs and the goal is to end the way drugs have been developed for the last century. Here is the problem it is trying to solve. Developing a single drug today takes an average of 10 years, costs billions of dollars, and fails 90 percent of the time before it ever reaches a patient. Of every 10 drugs that enter clinical trials, only one makes it through. The other nine years of work, the other billions of dollars, the other scientific careers, gone. Hassabis believes AI can collapse that entire process from identifying a disease target to designing a compound that binds to it, predicts how it behaves in the body, and minimizes side effects , end to end, on a computer, before a single experiment is run. The foundation is AlphaFold, the AI system that solved one of biology's hardest problems predicting the 3D structure of every protein in the human body and won him the Nobel Prize in Chemistry in 2024. But knowing a protein's shape is only one part of designing a drug. Isomorphic is building what Hassabis describes as adjacent systems , AlphaFold 3, AlphaFold 4, and now a unified model called IsoDDE , that take the next steps. From designing the actual chemical compound that binds to the protein, predicting its binding strength, identifying new pockets to target that no one has ever found before. IsoDDE more than doubles the accuracy of AlphaFold 3 on the hardest protein-ligand prediction benchmarks that exist. Isomorphic is already running 18 to 19 live drug programs, cardiovascular disease, cancer, immunology in partnership with Eli Lilly, Novartis, and Johnson and Johnson. The first human clinical trial of a fully AI-designed drug is expected by the end of 2026. If that trial succeeds, it will be the first time in history that a drug put into a human body was designed not by a team of chemists working for a decade but by an AI working for months. Hassabis's long-term vision is even more direct, one day you describe a disease, click a button, and a drug blueprint comes out the other side. AI will solve almost all diseases within 10 years.

Milk Road AI

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