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Here is gingerBill spontaneously: - giving a lecture on async io vs sync io (that's more coherent and visually pleasing than most universities) - walking through 3 major OS asyncio apis - IMPLEMENTING asyncio for Odin - and another piece of lecture on coloring functions, that morphs into async/await...

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Łukasz | Wookash Podcast

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19,810 Aufrufe • vor 6 Monaten •via X (Twitter)

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Why did so many languages copy async/await from C#? Anders Hejlsberg(Anders Hejlsberg) - creator of TypeScript, C# & Turbo Pascal - on what they got right with the design: #1 - async/await was designed to solve a common problem in the event-loop model: "A lot of languages are built around cooperative multitasking in the sense that they have an event loop that sits and dispatches events. Then you handle the event and then you yield back to the event handler loop. And it all runs in a single thread cooperatively. The problem with that is if you then want to do some long running work: how do I stop in the middle of this piece of long running work and yield back to the event loop cooperatively? And then when my result is ready, I can come back and continue executing here." #2 - state machines are the solution, but hard to build: "Well, in order to do that in an inverted architecture like that, you have to build a state machine. State machines are notoriously hard for people to implement because you've got to move all of your state off of the stack into objects. And then you have this big case statement that envelopes your entire logic. It's a nightmare to figure out. But, the transformation from serially executing code into a state machine, its continuation-passing-style translation is actually one that you can do in a machine-based fashion." #3 - compilers are good at writing state machines: "You can have the compiler write the state machine if you introduce syntax that allows you to indicate where you want to yield. And that's what await is. Await is basically saying, I want to yield here, and I want to yield this promise, and then when the promise completes, I want you to come back here and continue executing. Then the compiler writes a state machine around it and it actually turns it into this big switch statement and moves all of the state that survives across the await into something that's heap allocated. So it can be brought back. And doing all of that work is something that compilers are great at. And so that was sort of the idea that we have this new style of programming where we're using promises or the equivalent of promises and the ability to yield and then we have callbacks. But trying to write your program in that style, that's also what JavaScript suffered from a lot. It's like all this callback style stuff. With Async and Await, you get the illusion that you're just writing normal sequential code and then the compiler does the painful transformation for you. That turns out to be really useful."
3:13

Why did so many languages copy async/await from C#? Anders Hejlsberg(Anders Hejlsberg) - creator of TypeScript, C# & Turbo Pascal - on what they got right with the design: #1 - async/await was designed to solve a common problem in the event-loop model: "A lot of languages are built around cooperative multitasking in the sense that they have an event loop that sits and dispatches events. Then you handle the event and then you yield back to the event handler loop. And it all runs in a single thread cooperatively. The problem with that is if you then want to do some long running work: how do I stop in the middle of this piece of long running work and yield back to the event loop cooperatively? And then when my result is ready, I can come back and continue executing here." #2 - state machines are the solution, but hard to build: "Well, in order to do that in an inverted architecture like that, you have to build a state machine. State machines are notoriously hard for people to implement because you've got to move all of your state off of the stack into objects. And then you have this big case statement that envelopes your entire logic. It's a nightmare to figure out. But, the transformation from serially executing code into a state machine, its continuation-passing-style translation is actually one that you can do in a machine-based fashion." #3 - compilers are good at writing state machines: "You can have the compiler write the state machine if you introduce syntax that allows you to indicate where you want to yield. And that's what await is. Await is basically saying, I want to yield here, and I want to yield this promise, and then when the promise completes, I want you to come back here and continue executing. Then the compiler writes a state machine around it and it actually turns it into this big switch statement and moves all of the state that survives across the await into something that's heap allocated. So it can be brought back. And doing all of that work is something that compilers are great at. And so that was sort of the idea that we have this new style of programming where we're using promises or the equivalent of promises and the ability to yield and then we have callbacks. But trying to write your program in that style, that's also what JavaScript suffered from a lot. It's like all this callback style stuff. With Async and Await, you get the illusion that you're just writing normal sequential code and then the compiler does the painful transformation for you. That turns out to be really useful."

The Pragmatic Engineer

13,258 Aufrufe • vor 1 Monat

Jim Simons made 66% a year for thirty years. Nobody has come close. Not Buffett. Not Soros. Not Druckenmiller. Every quant fund since has tried to reverse-engineer what Renaissance actually does. They keep landing on the same wrong answer: "More data. More compute. More simulations." Last November, a mathematician from Stanford gave a lecture that explains why they'll never catch up. His name is Persi Diaconis. He's the world's authority on when a simulation is telling you the truth and when it's telling you a story. His conclusion after forty years of research: most of the simulations Wall Street runs today are giving persistently wrong results, and no amount of GPU will fix it. The answer isn't more compute. The answer is proof. Simons required a proof before deploying a strategy. That's the part nobody copied. That's the part they can't. Lecture below. Under an hour. The most important hour you'll spend on markets this year.
1:00:30

Jim Simons made 66% a year for thirty years. Nobody has come close. Not Buffett. Not Soros. Not Druckenmiller. Every quant fund since has tried to reverse-engineer what Renaissance actually does. They keep landing on the same wrong answer: "More data. More compute. More simulations." Last November, a mathematician from Stanford gave a lecture that explains why they'll never catch up. His name is Persi Diaconis. He's the world's authority on when a simulation is telling you the truth and when it's telling you a story. His conclusion after forty years of research: most of the simulations Wall Street runs today are giving persistently wrong results, and no amount of GPU will fix it. The answer isn't more compute. The answer is proof. Simons required a proof before deploying a strategy. That's the part nobody copied. That's the part they can't. Lecture below. Under an hour. The most important hour you'll spend on markets this year.

kairos

92,297 Aufrufe • vor 12 Tagen

Introducing, Team1 India What started as a group of 4 is now a network of 40 active contributors driving blockchain adoption and growth for Avalanche in India. • 100+ events across 30+ cities and 20+ universities • 4,000+ attendees • 3,500+ developer applications for our 7-city hackathon tour The mission is straightforward: We are building the network that ensures India remains one of the global leaders when it comes to blockchain and talent. Speculation is gone, replaced by a founder-friendly ecosystem where community, real-world products, and high-quality outcomes are the only metrics that matter. Team1 India is doubling down on our most ambitious builders, moving founders from conceptual projects into thriving, market-ready solutions. Mentorship through hands-on workshops for students and brighter spotlights on local talent ensure that Team1 India is cultivating a builder culture that onboards and nurtures talent. The journey continues, stronger and more focused than ever. Follow us here and join our community Telegram below to get more involved.
0:33

Introducing, Team1 India What started as a group of 4 is now a network of 40 active contributors driving blockchain adoption and growth for Avalanche in India. • 100+ events across 30+ cities and 20+ universities • 4,000+ attendees • 3,500+ developer applications for our 7-city hackathon tour The mission is straightforward: We are building the network that ensures India remains one of the global leaders when it comes to blockchain and talent. Speculation is gone, replaced by a founder-friendly ecosystem where community, real-world products, and high-quality outcomes are the only metrics that matter. Team1 India is doubling down on our most ambitious builders, moving founders from conceptual projects into thriving, market-ready solutions. Mentorship through hands-on workshops for students and brighter spotlights on local talent ensure that Team1 India is cultivating a builder culture that onboards and nurtures talent. The journey continues, stronger and more focused than ever. Follow us here and join our community Telegram below to get more involved.

Team1 India

40,462 Aufrufe • vor 4 Monaten

Yesterday, I had the privilege of delivering the Annual Public Lecture at Osun State University, Osogbo on the invitation of the institution’s leadership. The lecture titled “Interrogating the Funding of Education: Global Versus Nigerian Perspectives.” A topic that could not have come at a better time as we try to fix our tertiary education system I underscored a central truth that though education in my opinion is a fundamental human right and not a privilege , it can also be very expensive. In Nigeria, where over 1.9 million young people apply to universities annually and more than 130 public universities operate across the federation, the old funding model is no longer sustainable. That is why, during my time as Speaker of the House of Representatives, I sponsored and led the passage of the Interest-free Students Loan (Access to Higher Education) Act 2023, a transformative piece of legislation aimed at ensuring that no capable Nigerian youth is denied a university education solely because they cannot afford fees. And in one of his earliest acts as President, President Bola Ahmed Tinubu a strong believer in education signed that bill into law, affirming the President’s commitment to access, equity, and opportunity to all Nigerians. Together, we laid the legislative and executive foundations for what has become a new era of inclusive tertiary education in Nigeria. In my address, I also encouraged our universities to take learn from global institutions that have successfully diversified their income through commercial ventures, research commercialization, and international student enrolment. Institutions like Harvard, Oxford, and MIT don’t just educate, they innovate, compete, and generate revenue through publishing, patents, and partnerships. Nigeria can do the same if we reimagine our public universities not as charitable institutions but as engines of development. But we must also confront the deep structural issues: unethical practices, lack of global competitiveness, outdated teaching methods, and poor infrastructure. Reforming higher education is not just about money it’s about standards, partnerships, and courage. Let us build universities that can compete globally, inspire students, and contribute economically. Let us through qualitative education erect ladders of opportunity for the younger generation.
2:02

Yesterday, I had the privilege of delivering the Annual Public Lecture at Osun State University, Osogbo on the invitation of the institution’s leadership. The lecture titled “Interrogating the Funding of Education: Global Versus Nigerian Perspectives.” A topic that could not have come at a better time as we try to fix our tertiary education system I underscored a central truth that though education in my opinion is a fundamental human right and not a privilege , it can also be very expensive. In Nigeria, where over 1.9 million young people apply to universities annually and more than 130 public universities operate across the federation, the old funding model is no longer sustainable. That is why, during my time as Speaker of the House of Representatives, I sponsored and led the passage of the Interest-free Students Loan (Access to Higher Education) Act 2023, a transformative piece of legislation aimed at ensuring that no capable Nigerian youth is denied a university education solely because they cannot afford fees. And in one of his earliest acts as President, President Bola Ahmed Tinubu a strong believer in education signed that bill into law, affirming the President’s commitment to access, equity, and opportunity to all Nigerians. Together, we laid the legislative and executive foundations for what has become a new era of inclusive tertiary education in Nigeria. In my address, I also encouraged our universities to take learn from global institutions that have successfully diversified their income through commercial ventures, research commercialization, and international student enrolment. Institutions like Harvard, Oxford, and MIT don’t just educate, they innovate, compete, and generate revenue through publishing, patents, and partnerships. Nigeria can do the same if we reimagine our public universities not as charitable institutions but as engines of development. But we must also confront the deep structural issues: unethical practices, lack of global competitiveness, outdated teaching methods, and poor infrastructure. Reforming higher education is not just about money it’s about standards, partnerships, and courage. Let us build universities that can compete globally, inspire students, and contribute economically. Let us through qualitative education erect ladders of opportunity for the younger generation.

Femi Gbajabiamila

23,160 Aufrufe • vor 1 Jahr

Daniel Kibret is Abiy’s right-hand man, a close confidant, and one of the most trusted figures in Abiy’s inner circle. He is almost always at Abiy’s side at public functions and acts as the chief ideologue of the Prosperity Party. He is well known for using Amharic idioms and prose to ridicule and insult opposition figures. In practice, he appears to wield more influence than many of Abiy’s Ministers. Recently, he delivered a lecture on #Ethiopia’s so-called strategic necessity regarding the Nile River and the Red Sea basin, making it clear that Abiy often serves as a mouthpiece for Daniel Kibret’s ideas or vice-versa. The lecture was delivered to members of the artistic community in Addis Ababa and was titled Ethiopia’s War of Narratives. Its purpose was to instruct them on how to campaign using new narratives to “enlighten” the Ethiopian public—particularly narratives centered on water. He argued that Ethiopia’s enemies have deliberately prevented the country from benefiting from the Nile and the Red Sea. The lecture is deeply dangerous in its intent, as it seeks to plant the seeds of conflict in the Horn of #Africa for generations to come. Daniel Kibret openly questioned the legitimacy of colonial-era borders, asking whether Ethiopia should accept or reject them there by attempting to break one of the main tenets of African Union African Union . He argued that accepting these boundaries would mean losing access to the Nile, abandoning claims to the Red Sea, and even being restricted from freely using the term “water” itself. He went on to note that Ethiopia only recently established a Ministry of Water, more than a century after the modern state was formed, and framed this as evidence of historical injustice. His central question was clear: should Ethiopia accept or reject colonial boundaries? Throughout the lecture, he made numerous false, misleading, and outright untrue claims. I will address these in detail in subsequent posts.
1:22

Daniel Kibret is Abiy’s right-hand man, a close confidant, and one of the most trusted figures in Abiy’s inner circle. He is almost always at Abiy’s side at public functions and acts as the chief ideologue of the Prosperity Party. He is well known for using Amharic idioms and prose to ridicule and insult opposition figures. In practice, he appears to wield more influence than many of Abiy’s Ministers. Recently, he delivered a lecture on #Ethiopia’s so-called strategic necessity regarding the Nile River and the Red Sea basin, making it clear that Abiy often serves as a mouthpiece for Daniel Kibret’s ideas or vice-versa. The lecture was delivered to members of the artistic community in Addis Ababa and was titled Ethiopia’s War of Narratives. Its purpose was to instruct them on how to campaign using new narratives to “enlighten” the Ethiopian public—particularly narratives centered on water. He argued that Ethiopia’s enemies have deliberately prevented the country from benefiting from the Nile and the Red Sea. The lecture is deeply dangerous in its intent, as it seeks to plant the seeds of conflict in the Horn of #Africa for generations to come. Daniel Kibret openly questioned the legitimacy of colonial-era borders, asking whether Ethiopia should accept or reject them there by attempting to break one of the main tenets of African Union African Union . He argued that accepting these boundaries would mean losing access to the Nile, abandoning claims to the Red Sea, and even being restricted from freely using the term “water” itself. He went on to note that Ethiopia only recently established a Ministry of Water, more than a century after the modern state was formed, and framed this as evidence of historical injustice. His central question was clear: should Ethiopia accept or reject colonial boundaries? Throughout the lecture, he made numerous false, misleading, and outright untrue claims. I will address these in detail in subsequent posts.

Sirak Bahlbi

10,675 Aufrufe • vor 7 Monaten

Are boots on the ground coming to Iran? The Trump administration is reportedly preparing for major military operations to force the reopening of the Strait of Hormuz. Brandon Weichert reports that key U.S. military assets are now being positioned near Iran, with discussions of a coastal island takeover that could drag the United States into a prolonged war. What is this operation really meant to accomplish? Can the Strait actually be secured through military force, or are we walking into another endless conflict with no clear exit? We discuss that, and more, in this interview.
3:46

Are boots on the ground coming to Iran? The Trump administration is reportedly preparing for major military operations to force the reopening of the Strait of Hormuz. Brandon Weichert reports that key U.S. military assets are now being positioned near Iran, with discussions of a coastal island takeover that could drag the United States into a prolonged war. What is this operation really meant to accomplish? Can the Strait actually be secured through military force, or are we walking into another endless conflict with no clear exit? We discuss that, and more, in this interview.

Redacted

15,214 Aufrufe • vor 2 Monaten

A Bonus render of Electron Holography for our Quantum Mechanics Lecture Series. We’re staging a TEM-style electron holography shot as a single 3D scene. A coherent electron wave ψ(x,y,t) enters from the left as a localized packet, gets split by a thin biprism phase wedge, then bends around a central nanoring that stands in for an enclosed magnetic flux. The wave evolves by Schrödinger dynamics, so its intensity ρ=|ψ|² is literally the electron detection probability density, while the probability current j=(1/m)Im(ψ*∇ψ) acts like a conserved flow of that density across the plane. The main surface is a living whose height tracks |ψ| and whose skin color cycles with arg(ψ). On top of it, luminous current ribbons trace streamlines of v=j/(ρ+ε), so you can see how phase gradients steer the flow around the ring and back into interference. High above, a tilted detector/hologram screen shows the off-axis fringe image you’d measure (intensity after mixing with a reference wave), while a porcelain bead marks the centroid ⟨x⟩(t) and flux threads through the ring pulse in sync with the Aharonov-Bohm phase knob φ_AB(t). See our lecture series for details. #QuantumMechanics #ElectronHolography #MathematicalPhysics #Physics
1:30

A Bonus render of Electron Holography for our Quantum Mechanics Lecture Series. We’re staging a TEM-style electron holography shot as a single 3D scene. A coherent electron wave ψ(x,y,t) enters from the left as a localized packet, gets split by a thin biprism phase wedge, then bends around a central nanoring that stands in for an enclosed magnetic flux. The wave evolves by Schrödinger dynamics, so its intensity ρ=|ψ|² is literally the electron detection probability density, while the probability current j=(1/m)Im(ψ*∇ψ) acts like a conserved flow of that density across the plane. The main surface is a living whose height tracks |ψ| and whose skin color cycles with arg(ψ). On top of it, luminous current ribbons trace streamlines of v=j/(ρ+ε), so you can see how phase gradients steer the flow around the ring and back into interference. High above, a tilted detector/hologram screen shows the off-axis fringe image you’d measure (intensity after mixing with a reference wave), while a porcelain bead marks the centroid ⟨x⟩(t) and flux threads through the ring pulse in sync with the Aharonov-Bohm phase knob φ_AB(t). See our lecture series for details. #QuantumMechanics #ElectronHolography #MathematicalPhysics #Physics

Mathelirium

14,252 Aufrufe • vor 6 Monaten

Persi Diaconis, Stanford mathematician and former professional magician: "I spent fifty years proving one thing: almost nothing is as random as it looks. The 50.75% that built Renaissance wasn't luck. It was a tiny crack in the randomness, found and repeated a million times." this free lecture holds the exact idea the thread above is built on. and the man giving it isn't a trader. he's a stanford professor and former professional magician who spent his career on one question: where does real randomness end, and where does a hidden edge begin. here is his life's finding. a coin, a shuffle, a market, all look random, yet each hides a faint, measurable bias. on its own that bias is nothing, indistinguishable from luck. repeat it enough times and it stops being luck and becomes a law. that faint crack, found and repeated, is the whole distance between a 50.75% win rate and a hundred billion dollars. none of this is new or hidden. diaconis has taught it for decades, the math runs back to 1713, and the lecture is free. i mapped the full system in my article, expected value, kelly, and this. same point the thread makes: the edge was sitting in plain sight. here is the part the gurus skip. a faint edge only pays if you survive long enough to reach it, and that takes correct sizing and the patience to trust it through thousands of losing-looking trades. most quit while it still looks like randomness. the math is free. the nerve to hold it is the edge.
48:41

Persi Diaconis, Stanford mathematician and former professional magician: "I spent fifty years proving one thing: almost nothing is as random as it looks. The 50.75% that built Renaissance wasn't luck. It was a tiny crack in the randomness, found and repeated a million times." this free lecture holds the exact idea the thread above is built on. and the man giving it isn't a trader. he's a stanford professor and former professional magician who spent his career on one question: where does real randomness end, and where does a hidden edge begin. here is his life's finding. a coin, a shuffle, a market, all look random, yet each hides a faint, measurable bias. on its own that bias is nothing, indistinguishable from luck. repeat it enough times and it stops being luck and becomes a law. that faint crack, found and repeated, is the whole distance between a 50.75% win rate and a hundred billion dollars. none of this is new or hidden. diaconis has taught it for decades, the math runs back to 1713, and the lecture is free. i mapped the full system in my article, expected value, kelly, and this. same point the thread makes: the edge was sitting in plain sight. here is the part the gurus skip. a faint edge only pays if you survive long enough to reach it, and that takes correct sizing and the patience to trust it through thousands of losing-looking trades. most quit while it still looks like randomness. the math is free. the nerve to hold it is the edge.

Rossst.03

229,785 Aufrufe • vor 27 Tagen

#BREAKING: President Trump today said regime change in #Iran "would be the best thing that could happen. For 47 years, they've been talking and talking and talking. In the meantime, we've lost a lot of lives while they talk. Legs blown off, arms blown off, faces blown off. We've been going on for a long time so let's see what happens." President Trump understands the dynamics here more than most people realize. He has no patience for the Islamic Republic's stalling. And this is a historic statement, following other historic statements, for an American president to make. It's gone further than his predecessors, who just used to express support for the Iranian people to exercise their rights.
0:31

#BREAKING: President Trump today said regime change in #Iran "would be the best thing that could happen. For 47 years, they've been talking and talking and talking. In the meantime, we've lost a lot of lives while they talk. Legs blown off, arms blown off, faces blown off. We've been going on for a long time so let's see what happens." President Trump understands the dynamics here more than most people realize. He has no patience for the Islamic Republic's stalling. And this is a historic statement, following other historic statements, for an American president to make. It's gone further than his predecessors, who just used to express support for the Iranian people to exercise their rights.

Jason Brodsky

495,003 Aufrufe • vor 5 Monaten

A CARNEGIE MELLON PROFESSOR WAS TOLD HE HAD 3 TO 6 MONTHS TO LIVE. One month later he walked into a packed auditorium. His name was Randy Pausch. He was 46 years old. He had terminal pancreatic cancer. He had three children under the age of 6. And he stood on that stage and gave the most joyful lecture ever recorded. He did not talk about dying. He did not talk about regret. He did not talk about the unfairness of what was happening to him. He talked about achieving childhood dreams. He did one-armed push-ups on stage to prove he was still strong. He made the audience laugh for 76 minutes straight. He said: "We cannot change the cards we are dealt. Just how we play the hand." The video hit 20 million views overnight. Oprah called. Congress called. He testified before the Senate about pancreatic cancer funding. He got a cameo in Star Trek because the director heard his story and personally invited him. He wrote a book that sold 5 million copies in 48 languages. He died 10 months after the lecture. He was 47 years old. The bridge connecting computer science and the arts at Carnegie Mellon is named after him. Because Randy Pausch spent his entire career connecting the two. Watch the lecture tonight. 4 minutes that will permanently change how you think about time. Bookmark this. Follow CyrilXBT for more stories about people who used their time better than anyone else alive.
4:42

A CARNEGIE MELLON PROFESSOR WAS TOLD HE HAD 3 TO 6 MONTHS TO LIVE. One month later he walked into a packed auditorium. His name was Randy Pausch. He was 46 years old. He had terminal pancreatic cancer. He had three children under the age of 6. And he stood on that stage and gave the most joyful lecture ever recorded. He did not talk about dying. He did not talk about regret. He did not talk about the unfairness of what was happening to him. He talked about achieving childhood dreams. He did one-armed push-ups on stage to prove he was still strong. He made the audience laugh for 76 minutes straight. He said: "We cannot change the cards we are dealt. Just how we play the hand." The video hit 20 million views overnight. Oprah called. Congress called. He testified before the Senate about pancreatic cancer funding. He got a cameo in Star Trek because the director heard his story and personally invited him. He wrote a book that sold 5 million copies in 48 languages. He died 10 months after the lecture. He was 47 years old. The bridge connecting computer science and the arts at Carnegie Mellon is named after him. Because Randy Pausch spent his entire career connecting the two. Watch the lecture tonight. 4 minutes that will permanently change how you think about time. Bookmark this. Follow CyrilXBT for more stories about people who used their time better than anyone else alive.

CyrilXBT

22,278 Aufrufe • vor 3 Monaten

#WATCH | Delhi | Speaking on governance at a lecture on Rashtriya Ekta Diwas, NSA Ajit Doval says, "...I take a capsule of the same last ten years... The facts are facts, and they cannot be disputed. Terrorism in this country has been effectively countered. We had a major incident of terrorism on 1st July 2005 and the last one in 2013 in the hinterland. Except for Jammu and Kashmir, which had been a theatre of a proxy war or a covert warfare for Pakistan, which is a different ballgame, the whole country has remained secure from terrorist attacks. Efforts were made. People were arrested. Explosives are recovered... Enemies have remained very active, but fortunately, and it's more of a good fortune in the country that we can say that we have had no terrorist incident in the hinterland. The left-wing extremism has reduced to less than 11% areas than what existed in 2014. Most of the districts which had been declared as left-wing prone have been declared safe..."
3:06

#WATCH | Delhi | Speaking on governance at a lecture on Rashtriya Ekta Diwas, NSA Ajit Doval says, "...I take a capsule of the same last ten years... The facts are facts, and they cannot be disputed. Terrorism in this country has been effectively countered. We had a major incident of terrorism on 1st July 2005 and the last one in 2013 in the hinterland. Except for Jammu and Kashmir, which had been a theatre of a proxy war or a covert warfare for Pakistan, which is a different ballgame, the whole country has remained secure from terrorist attacks. Efforts were made. People were arrested. Explosives are recovered... Enemies have remained very active, but fortunately, and it's more of a good fortune in the country that we can say that we have had no terrorist incident in the hinterland. The left-wing extremism has reduced to less than 11% areas than what existed in 2014. Most of the districts which had been declared as left-wing prone have been declared safe..."

ANI

227,063 Aufrufe • vor 9 Monaten

Apple is a baby fox rescued by Kimberly, founder of Arctic Fox Daily Rescue. 🦊🍎 Apple has hydrocephalus, a serious condition that makes life very hard for baby foxes, and most baby foxes with this condition are not given a real chance. But Kimberly did not give up. Now Apple may need expensive treatment or surgery, and the solana:Aw5SxKyYhXFdZj2BHCqs11UaV5ohwpFQjauB9jFhpump community is here to help. All fees from solana:Aw5SxKyYhXFdZj2BHCqs11UaV5ohwpFQjauB9jFhpump are being donated to Arctic Fox Daily Rescue through the PumpFun charity feature. So far, we raised $67,322 and became a Top 3 charity coin on Kimberly has noticed the solana:Aw5SxKyYhXFdZj2BHCqs11UaV5ohwpFQjauB9jFhpump movement and thanked the community for standing with Apple on TikTok. link: This is more than a meme. This is a real charity coin with a real mission. We are helping Apple fight for her life and giving hope to more baby foxes like her. 🦊🦊🍎
1:04

Apple is a baby fox rescued by Kimberly, founder of Arctic Fox Daily Rescue. 🦊🍎 Apple has hydrocephalus, a serious condition that makes life very hard for baby foxes, and most baby foxes with this condition are not given a real chance. But Kimberly did not give up. Now Apple may need expensive treatment or surgery, and the solana:Aw5SxKyYhXFdZj2BHCqs11UaV5ohwpFQjauB9jFhpump community is here to help. All fees from solana:Aw5SxKyYhXFdZj2BHCqs11UaV5ohwpFQjauB9jFhpump are being donated to Arctic Fox Daily Rescue through the PumpFun charity feature. So far, we raised $67,322 and became a Top 3 charity coin on Kimberly has noticed the solana:Aw5SxKyYhXFdZj2BHCqs11UaV5ohwpFQjauB9jFhpump movement and thanked the community for standing with Apple on TikTok. link: This is more than a meme. This is a real charity coin with a real mission. We are helping Apple fight for her life and giving hope to more baby foxes like her. 🦊🦊🍎

Apple

123,118 Aufrufe • vor 2 Monaten

Talk about spreading your seed 😳 what do y’all think about this? Pavel Durov, estimated to be worth around $15 billion, is the founder of Telegram, and sometimes referred to as “the Elon Musk of Russia.” He’s making waves for offering free IVF and sperm donations to women who want to have his children. Already a father to more than 100 children through sperm donations, Durov is currently reported to be under criminal investigation in France and can’t leave the country. What’s interesting is that this story taps into larger trends we’re seeing today. By 2030, economists and researchers predict that 45% of women in the U.S. will be single and childless. That’s a record-high stat and one that stirred up major discussion in the comments on my recent post. Many women today are finding themselves on different paths than past generations, whether focusing on careers, delaying family life, or opting out of motherhood altogether. So, what do you think of Durov’s “donation” strategy and the changing trends around family? Is this part of a new age of reproductive choices, or does it raise more concerns than solutions?
0:40

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Talk about spreading your seed 😳 what do y’all think about this? Pavel Durov, estimated to be worth around $15 billion, is the founder of Telegram, and sometimes referred to as “the Elon Musk of Russia.” He’s making waves for offering free IVF and sperm donations to women who want to have his children. Already a father to more than 100 children through sperm donations, Durov is currently reported to be under criminal investigation in France and can’t leave the country. What’s interesting is that this story taps into larger trends we’re seeing today. By 2030, economists and researchers predict that 45% of women in the U.S. will be single and childless. That’s a record-high stat and one that stirred up major discussion in the comments on my recent post. Many women today are finding themselves on different paths than past generations, whether focusing on careers, delaying family life, or opting out of motherhood altogether. So, what do you think of Durov’s “donation” strategy and the changing trends around family? Is this part of a new age of reproductive choices, or does it raise more concerns than solutions?

TERANN HILOW

24,435 Aufrufe • vor 1 Jahr

Most people treat self-talk like a pep talk — you tell yourself you've got this, you stay positive, you push through. That advice isn't wrong. It's just incomplete in a way that matters more than most people realize. The research on positive self-talk is real. Encouraging internal dialogue does improve performance. But the field has largely moved away from framing this as "positive vs. negative" because that's not actually the right question. The right question is whether what you're saying to yourself is *effective*. And negative self-talk can be effective. Positive self-talk can be useless. The valence isn't the variable. What actually drives effectiveness is something most self-talk advice never mentions: psychological distance. Here's the thing: you're probably already an expert at this, just not for yourself. Think about a scenario you find stressful — an exam, a tough conversation, a high-pressure week. Now picture a friend in that same situation texting you about it. You know exactly what to say back. You're not scrambling. You're not spiraling. Because you're not inside the emotion of it. That clarity you have for them? That's the same clarity psychological distance gives you for yourself. Your inner voice isn't your best coach. It's your most reactive one.
0:48

Most people treat self-talk like a pep talk — you tell yourself you've got this, you stay positive, you push through. That advice isn't wrong. It's just incomplete in a way that matters more than most people realize. The research on positive self-talk is real. Encouraging internal dialogue does improve performance. But the field has largely moved away from framing this as "positive vs. negative" because that's not actually the right question. The right question is whether what you're saying to yourself is *effective*. And negative self-talk can be effective. Positive self-talk can be useless. The valence isn't the variable. What actually drives effectiveness is something most self-talk advice never mentions: psychological distance. Here's the thing: you're probably already an expert at this, just not for yourself. Think about a scenario you find stressful — an exam, a tough conversation, a high-pressure week. Now picture a friend in that same situation texting you about it. You know exactly what to say back. You're not scrambling. You're not spiraling. Because you're not inside the emotion of it. That clarity you have for them? That's the same clarity psychological distance gives you for yourself. Your inner voice isn't your best coach. It's your most reactive one.

Andy Galpin, PhD

70,643 Aufrufe • vor 3 Monaten

Wow, first I discovered the 2007 NIH workshop that ranked Il-15 the number one immunotherapy to cure cancer, now I find a 2017 lecture on IL-15 by NIH AND NCI describing its power. Building on the shoulders of immunology giants at the NIH and NCI , the late Drs William E. Paul and Thomas Waldman. This is such an important lecture for all to listen to and to comprehend the future of immunotherapy 2.0. I post the video in my tweet in which we have shortened the introduction to start with the lecture. The full video is here: The immense power and value of IL-15 was recognized almost 20 years ago. Amazingly, Dr. Waldman foresaw the need to COMBINE IL-15 (today's ANKTIVA) with a checkpoint inhibitor (today's Keytruda) in order to maximize T cell activity as well as stimulate macrophages (today’s Abraxane). This is what the Saudi FDA scientists and regulators at the SFDA recognized - the power of IL15 and Anktiva as the backbone and that is why we have the world's first approval for ANKTIVA in combination with checkpoint inhibitor in Saudi Arabia. This is such an important lecture that every regulatory authority in the world should study and understand the evolutionary science of the immune system and the importance of appropriate combinations… so important for science to drive regulatory decision-making, especially for the reviewers who may not be trained immunologists and coming to conclusions based on past archaic practices. Oncology and infectious disease is now fundamental immunology. So hopeful that regulatory reviewers around the world watch this... It is such an important educational video of what we have been building at IBRX that I will leave this pinned for a month!!! So inspired to see that we have been independently pursuing the right strategy for the past decade. The power of immunotherapy 2.0 is clearly spelt out in Dr Walkman’s talk in 2017 where he explains why T cell memory is needed to cure cancer and why orchestrated sequenced combinations are needed. Anktiva which grows and activates T and NK cells, Abraxane that induces DAMPs and activates macrophages, and checkpoint inhibitors that take the brakes off T cells is THE FUNDAMENTAL COMBINATION DESCRIBED by NCI scientists a decade ago in this lecture! Remarkably, Dr. Waldman shows that when administered as single-agents, these molecules did not achieve durable complete remissions but when placed in the correct sequence of combination therapy, magic happens. Quantum oncotherapeutics So please share this video with whomever wants to be enlightened that immunotherapy 2.0 now exists and has been studied in multiple Quantum Oncotherapeutics trials across multiple tumor types under QUILT
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Wow, first I discovered the 2007 NIH workshop that ranked Il-15 the number one immunotherapy to cure cancer, now I find a 2017 lecture on IL-15 by NIH AND NCI describing its power. Building on the shoulders of immunology giants at the NIH and NCI , the late Drs William E. Paul and Thomas Waldman. This is such an important lecture for all to listen to and to comprehend the future of immunotherapy 2.0. I post the video in my tweet in which we have shortened the introduction to start with the lecture. The full video is here: The immense power and value of IL-15 was recognized almost 20 years ago. Amazingly, Dr. Waldman foresaw the need to COMBINE IL-15 (today's ANKTIVA) with a checkpoint inhibitor (today's Keytruda) in order to maximize T cell activity as well as stimulate macrophages (today’s Abraxane). This is what the Saudi FDA scientists and regulators at the SFDA recognized - the power of IL15 and Anktiva as the backbone and that is why we have the world's first approval for ANKTIVA in combination with checkpoint inhibitor in Saudi Arabia. This is such an important lecture that every regulatory authority in the world should study and understand the evolutionary science of the immune system and the importance of appropriate combinations… so important for science to drive regulatory decision-making, especially for the reviewers who may not be trained immunologists and coming to conclusions based on past archaic practices. Oncology and infectious disease is now fundamental immunology. So hopeful that regulatory reviewers around the world watch this... It is such an important educational video of what we have been building at IBRX that I will leave this pinned for a month!!! So inspired to see that we have been independently pursuing the right strategy for the past decade. The power of immunotherapy 2.0 is clearly spelt out in Dr Walkman’s talk in 2017 where he explains why T cell memory is needed to cure cancer and why orchestrated sequenced combinations are needed. Anktiva which grows and activates T and NK cells, Abraxane that induces DAMPs and activates macrophages, and checkpoint inhibitors that take the brakes off T cells is THE FUNDAMENTAL COMBINATION DESCRIBED by NCI scientists a decade ago in this lecture! Remarkably, Dr. Waldman shows that when administered as single-agents, these molecules did not achieve durable complete remissions but when placed in the correct sequence of combination therapy, magic happens. Quantum oncotherapeutics So please share this video with whomever wants to be enlightened that immunotherapy 2.0 now exists and has been studied in multiple Quantum Oncotherapeutics trials across multiple tumor types under QUILT

Dr. Pat Soon-Shiong

183,339 Aufrufe • vor 4 Monaten

CHINESE BUSINESSMAN BOUGHT 4 MAC MINIS FOR $1,699 AND CONNECTED THEM TO HIS MACBOOK - NOW THE CORNER OF HIS DESK MAKES MORE THAN MOST OFFICES MacBook Pro 16" runs everything - assigns tasks, controls the flow, holds context - 4 Mac Minis in the corner execute inference in parallel and don't know what downtime means he connected them through EXO - an open source framework that combines multiple Apple Silicon devices into one unified cluster - and together they run models no single device could handle alone while everyone else rents cloud GPUs for $1,900/month he paid $1,699 once and the entire cluster now runs on $20/month in electricity and nothing else clients pay for inference, data never leaves the room and the cluster scales by simply placing one more Mac Mini on top the MacBook is what he works on - the Mac Minis are what work for him around the clock without days off $1,699 invested once - and a corner of a desk that makes more than most companies with a rented office
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CHINESE BUSINESSMAN BOUGHT 4 MAC MINIS FOR $1,699 AND CONNECTED THEM TO HIS MACBOOK - NOW THE CORNER OF HIS DESK MAKES MORE THAN MOST OFFICES MacBook Pro 16" runs everything - assigns tasks, controls the flow, holds context - 4 Mac Minis in the corner execute inference in parallel and don't know what downtime means he connected them through EXO - an open source framework that combines multiple Apple Silicon devices into one unified cluster - and together they run models no single device could handle alone while everyone else rents cloud GPUs for $1,900/month he paid $1,699 once and the entire cluster now runs on $20/month in electricity and nothing else clients pay for inference, data never leaves the room and the cluster scales by simply placing one more Mac Mini on top the MacBook is what he works on - the Mac Minis are what work for him around the clock without days off $1,699 invested once - and a corner of a desk that makes more than most companies with a rented office

Noisy

22,375 Aufrufe • vor 1 Monat

Thoughts on the morning drive! My office nailed the FBI’s most wanted child pornographer right here in North Alabama! I told you that the folks I work with are amazing and really good at what they do at the Office of the US Attorney for the Northern District of Alabama. Well, here’s another example: William Michael Spearman was a sick individual who ran the worlds largest child porn network on the dark web. It was international in scope. It’s very likely that thousands, maybe tens of thousands, of innocent children were victims of the filth that he coordinated on his network. He ran employees, gave directions, promoted and perpetrated child exploitation in such a size and scope that he became the FBI’s most wanted child pornographer! And he lived and worked in Madison, Alabama! My office secured the warrants that led to the FBI conducting a no-knock raid on his house and seizing his servers and taking him into custody. My office also worked the detention hearings. He was tried and convicted in another district and received a life sentence. He is now off the streets, and off the web. We may never know how many victims there were. But my office helped to get that massive child porn ring shut down….right here in North Alabama. More of that please! Thoughts on the morning drive.
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Thoughts on the morning drive! My office nailed the FBI’s most wanted child pornographer right here in North Alabama! I told you that the folks I work with are amazing and really good at what they do at the Office of the US Attorney for the Northern District of Alabama. Well, here’s another example: William Michael Spearman was a sick individual who ran the worlds largest child porn network on the dark web. It was international in scope. It’s very likely that thousands, maybe tens of thousands, of innocent children were victims of the filth that he coordinated on his network. He ran employees, gave directions, promoted and perpetrated child exploitation in such a size and scope that he became the FBI’s most wanted child pornographer! And he lived and worked in Madison, Alabama! My office secured the warrants that led to the FBI conducting a no-knock raid on his house and seizing his servers and taking him into custody. My office also worked the detention hearings. He was tried and convicted in another district and received a life sentence. He is now off the streets, and off the web. We may never know how many victims there were. But my office helped to get that massive child porn ring shut down….right here in North Alabama. More of that please! Thoughts on the morning drive.

Phil Williams

15,848 Aufrufe • vor 22 Tagen

“As CEO and cofounder of Stord, he’s building the infrastructure—fulfillment, warehousing, and supply chain software—that empowers businesses to run and scale their own online operations. The company has ambitious goals in a chaotic time: to help brands compete with Amazon in a macroeconomic time characterized by moving-target-tariffs.” - Allie Garfinkle senior finance reporter for Fortune, Stord is The Consumer Experience Company, and today we take another step towards leveling the playing field so all brands can provide an exemplary pre-purchase through post-delivery experience on every order, every time. Because today, Stord has raised more than $200 million in equity and debt financing at a valuation of $1.5 billion. Thank you to FORTUNE and Allie Garfinkle for covering this major event in our history. Read the full piece here
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“As CEO and cofounder of Stord, he’s building the infrastructure—fulfillment, warehousing, and supply chain software—that empowers businesses to run and scale their own online operations. The company has ambitious goals in a chaotic time: to help brands compete with Amazon in a macroeconomic time characterized by moving-target-tariffs.” - Allie Garfinkle senior finance reporter for Fortune, Stord is The Consumer Experience Company, and today we take another step towards leveling the playing field so all brands can provide an exemplary pre-purchase through post-delivery experience on every order, every time. Because today, Stord has raised more than $200 million in equity and debt financing at a valuation of $1.5 billion. Thank you to FORTUNE and Allie Garfinkle for covering this major event in our history. Read the full piece here

Sean Henry

60,945 Aufrufe • vor 1 Jahr