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Hormone replacement therapy (HRT) is not dangerous. Timing and formulation are critical components of benefit vs. harm. I’m glad to see the FDA warnings removed from HRT. Thanks Carol Massar and Tim Stenovec at Bloomberg for covering this important topic. We need to understand when and how #HRT could...

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Fanny Elahi, MD, PhD

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14,185 Aufrufe • vor 9 Monaten •via X (Twitter)

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Fanny Elahi, MD, PhDvor 9 Monaten

Now let’s generate the data to deliver personalized, science-backed care for women’s health. Especially vascular-brain health 🧠🫀 @SinaiBrain @IcahnMountSinai @MountSinaiNYC

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CarolAnn Barrows 😷 🍍 🙏vor 9 Monaten

Why is a Neurologist speaking out about Hormone Replacement Therapy???? When @FannyElahi states emphatically that "hormone replacement therapy is not dangerous", is she ignoring the research regarding the evidence that Estrogen Replacement Therapy increases the risk of cancer of the uterus ( endometrial cancer)?

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🕯💧ShazH @shazh.bsky.socialvor 9 Monaten

@carolmassar @timsteno @Bloomberg I think a generic sentence is dangerous. As a survivor of hormone receptor positive cancer, my specialists have repeatedly warned against me taking HRT despite severe menopause symptoms. The heightened risk of cancer returning for me outweighs any benefits of HRT.

Profilbild von Fanny Elahi, MD, PhD
Fanny Elahi, MD, PhDvor 9 Monaten

My message to all women is to have the conversation about HRT with their providers. Many could safely benefit from HRT but have been afraid to consider based on the WHI study that led to FDA warnings. In that study HRT was started too late. Indeed, not everyone can be on HRT. That’s why we also need to understand how hormones benefit the brain and other organs in order to develop treatments that can bypass HRT for those who cannot safely be placed on HRT. We need so much more research on this. Our contributions to this important area of research will be focused on understanding how HRT could help brain health by maintaining vascular health.

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Magneto_SilverSurfervor 6 Monaten

@carolmassar @timsteno @Bloomberg Cholesterol protects the brain.

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Hormone Replacement Therapy (HRT) has long been an important treatment option for women to alleviate symptoms of menopause, among other potential health benefits. Over the last two decades, however, HRT has been surrounded by confusing narratives about potential risks. We're convening an expert panel at the FDA on July 17, 1-3 p.m. ET to discuss the latest evidence. Join us live at
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Hormone Replacement Therapy (HRT) has long been an important treatment option for women to alleviate symptoms of menopause, among other potential health benefits. Over the last two decades, however, HRT has been surrounded by confusing narratives about potential risks. We're convening an expert panel at the FDA on July 17, 1-3 p.m. ET to discuss the latest evidence. Join us live at

Dr. Marty Makary

277,913 Aufrufe • vor 1 Jahr

For anyone reading the headlines about HRT and dementia this morning, please watch this. The study referenced is an observational study so does not prove cause and effect. Also, it’s mainly looking at women who are taking older types of HRT which are very different to the types of HRT we prescribe now. Other studies have shown that people who take body identical HRT have a lower risk of dementia. What it does show is that we urgently need to do more research in this area.
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For anyone reading the headlines about HRT and dementia this morning, please watch this. The study referenced is an observational study so does not prove cause and effect. Also, it’s mainly looking at women who are taking older types of HRT which are very different to the types of HRT we prescribe now. Other studies have shown that people who take body identical HRT have a lower risk of dementia. What it does show is that we urgently need to do more research in this area.

Dr Louise Newson

271,591 Aufrufe • vor 3 Jahren

In the UK, only around 14% of menopausal women take HRT and this number usually shocks people. But as you can hear Dr Mary Claire Haver talk about here - in the US it is only 4% now, when just over 20 years ago it was around 40%. Much of this reduction in HRT use and the negativity regarding HRT stems from the misinterpretation of the Women’s Health Initiative (WHI) study which was published in 2002. For those of you who don’t know much about this, in 1993, the WHI began a clinical trial looking at the health effects of women taking oestrogen-only or combined HRT compared to a placebo. In 2002, researchers halted the part of the study looking at women taking both oestrogen and progesterone (two hormones that decline during the perimenopause onwards) early over concerns there were small increased risks of breast cancer, heart disease, strokes and blood clots. This led to confusion and concern from doctors and women worldwide, and in the UK women taking HRT fell sharply. But even with the older versions of HRT, the WHI researchers have subsequently acknowledged that HRT is the most effective treatment for managing menopausal symptoms like hot flushes and that taking oestrogen alone reduces the risk of breast cancer by 23% and death by breast cancer by 40%. It is time we move on from the misinterpretation of this study and allow more women to access hormone replacement if that is what they want.
1:19

In the UK, only around 14% of menopausal women take HRT and this number usually shocks people. But as you can hear Dr Mary Claire Haver talk about here - in the US it is only 4% now, when just over 20 years ago it was around 40%. Much of this reduction in HRT use and the negativity regarding HRT stems from the misinterpretation of the Women’s Health Initiative (WHI) study which was published in 2002. For those of you who don’t know much about this, in 1993, the WHI began a clinical trial looking at the health effects of women taking oestrogen-only or combined HRT compared to a placebo. In 2002, researchers halted the part of the study looking at women taking both oestrogen and progesterone (two hormones that decline during the perimenopause onwards) early over concerns there were small increased risks of breast cancer, heart disease, strokes and blood clots. This led to confusion and concern from doctors and women worldwide, and in the UK women taking HRT fell sharply. But even with the older versions of HRT, the WHI researchers have subsequently acknowledged that HRT is the most effective treatment for managing menopausal symptoms like hot flushes and that taking oestrogen alone reduces the risk of breast cancer by 23% and death by breast cancer by 40%. It is time we move on from the misinterpretation of this study and allow more women to access hormone replacement if that is what they want.

Dr Louise Newson

39,139 Aufrufe • vor 2 Jahren

I often have women messaging me to ask if there is a cut off age for taking HRT, or to ask what age they need to stop HRT. The answer is that there is usually no set length of time you should take HRT for - the menopause is a long-term hormone deficiency so women can usually take HRT forever to replace these missing hormones. However, after the Women’s Health Initiative Study was published in 2002, many women have resisted taking HRT, especially after age 65 years, because of fears of perceived risks. However, a new study has been published today showing that these fears are unfounded. The study also showed that women who took oestrogen only HRT beyond the age of 65 was associated with significant risk reductions in mortality, breast cancer, lung cancer, colorectal cancer, congestive heart failure, venous thromboembolism, atrial fibrillation, acute myocardial infarction, and dementia. There were also benefits to future health in women who took combination oestrogen and progesterone. The most benefit was with transdermal oestradiol and progesterone. If you haven’t yet read the study, I would really recommend you do. The link is here: It’s also worth listening to this podcast I recorded with Dr Anna Chiles who is a GP and works with us at Newson Health as a menopause specialist, as we talk more about continuing HRT for many years during that: This article we have on our @balancemenopause website is also worth a read:
0:48

I often have women messaging me to ask if there is a cut off age for taking HRT, or to ask what age they need to stop HRT. The answer is that there is usually no set length of time you should take HRT for - the menopause is a long-term hormone deficiency so women can usually take HRT forever to replace these missing hormones. However, after the Women’s Health Initiative Study was published in 2002, many women have resisted taking HRT, especially after age 65 years, because of fears of perceived risks. However, a new study has been published today showing that these fears are unfounded. The study also showed that women who took oestrogen only HRT beyond the age of 65 was associated with significant risk reductions in mortality, breast cancer, lung cancer, colorectal cancer, congestive heart failure, venous thromboembolism, atrial fibrillation, acute myocardial infarction, and dementia. There were also benefits to future health in women who took combination oestrogen and progesterone. The most benefit was with transdermal oestradiol and progesterone. If you haven’t yet read the study, I would really recommend you do. The link is here: It’s also worth listening to this podcast I recorded with Dr Anna Chiles who is a GP and works with us at Newson Health as a menopause specialist, as we talk more about continuing HRT for many years during that: This article we have on our @balancemenopause website is also worth a read:

Dr Louise Newson

95,527 Aufrufe • vor 2 Jahren

I attended the Royal College of Psychiatrists International Congress in Liverpool a few weeks ago and I wanted to share some really important clips from Professor Jayashri Kulkarni’s talk (who is a psychiatrist specialising in women’s mental health). Way too often, declining hormones are overlooked in women with low mood and depression, which can mean HRT isn’t offered. I see many women in my clinic who see a huge improvement in their mood after starting HRT so it’s really important we (women and healthcare professionals) take a holistic approach to treatment. HRT can be taken with antidepressants too.
1:29

I attended the Royal College of Psychiatrists International Congress in Liverpool a few weeks ago and I wanted to share some really important clips from Professor Jayashri Kulkarni’s talk (who is a psychiatrist specialising in women’s mental health). Way too often, declining hormones are overlooked in women with low mood and depression, which can mean HRT isn’t offered. I see many women in my clinic who see a huge improvement in their mood after starting HRT so it’s really important we (women and healthcare professionals) take a holistic approach to treatment. HRT can be taken with antidepressants too.

Dr Louise Newson

46,629 Aufrufe • vor 3 Jahren

HRT and the contraceptive pill both work by altering hormone levels in the body. My perspective on how these approaches may influence the body’s natural hormonal balance and why it’s important to understand how they work before deciding to use them 🌿 Understanding the body and learning about the effects of different options can help support more informed choices about hormonal health.
1:05

HRT and the contraceptive pill both work by altering hormone levels in the body. My perspective on how these approaches may influence the body’s natural hormonal balance and why it’s important to understand how they work before deciding to use them 🌿 Understanding the body and learning about the effects of different options can help support more informed choices about hormonal health.

Barbara Oneill

21,404 Aufrufe • vor 4 Monaten

Women have been misled by medical dogma for decades. It's time for the truth about Hormone Replacement Therapy (HRT). As Dr. Marty Makary explains, the pervasive fear that HRT increases a woman's risk of dying from breast cancer is not supported by clinical trial data. This critical misunderstanding has robbed countless women of profound health benefits. The short-term relief from perimenopause symptoms—like hot flashes, night sweats, and mood swings—is well-known. But the long-term benefits are truly staggering and largely underappreciated: ✅ Cuts the risk of heart attacks by 25-50% (the #1 killer of women). ✅ Reduces the risk of cognitive decline & Alzheimer's by up to 64%. ✅ Slashes the risk of osteoporosis and debilitating bone fractures in half. When initiated within 10 years of perimenopause, HRT may be one of the most impactful preventive medications in modern history for improving women's long-term health outcomes on a population level. Yet, as Dr. Makary points out, it remains underrecognized, underappreciated, and underfunded. This is a pivotal issue in women's health that demands attention. Every woman deserves to know the real data, beyond the outdated dogma, to make an informed decision with her doctor.
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Women have been misled by medical dogma for decades. It's time for the truth about Hormone Replacement Therapy (HRT). As Dr. Marty Makary explains, the pervasive fear that HRT increases a woman's risk of dying from breast cancer is not supported by clinical trial data. This critical misunderstanding has robbed countless women of profound health benefits. The short-term relief from perimenopause symptoms—like hot flashes, night sweats, and mood swings—is well-known. But the long-term benefits are truly staggering and largely underappreciated: ✅ Cuts the risk of heart attacks by 25-50% (the #1 killer of women). ✅ Reduces the risk of cognitive decline & Alzheimer's by up to 64%. ✅ Slashes the risk of osteoporosis and debilitating bone fractures in half. When initiated within 10 years of perimenopause, HRT may be one of the most impactful preventive medications in modern history for improving women's long-term health outcomes on a population level. Yet, as Dr. Makary points out, it remains underrecognized, underappreciated, and underfunded. This is a pivotal issue in women's health that demands attention. Every woman deserves to know the real data, beyond the outdated dogma, to make an informed decision with her doctor.

Camus

83,549 Aufrufe • vor 1 Jahr

FDA Commissioner Dr. Marty Makary calls the demonization of hormone replacement therapy (HRT) for postmenopausal women “the biggest screw-up of modern medicine.” Key points from his explosive take: - A misinterpreted 2002 NIH study (led by a Fauci-like figure) claimed HRT causes breast cancer — but the increase was not statistically significant, and no subsequent study has shown increased breast cancer mortality. - Women were scared off a treatment that dramatically improves quality of life and extends life. - Benefits include: - 25–50% lower risk of fatal heart attacks (leading killer in women) - ~90% reduction in osteoporosis risk - Prevention of cognitive decline - Relief from severe symptoms lasting ~8 years on average (hot flashes, night sweats, mood swings, painful sex, weight gain) - Marriages have been saved, lives improved — yet doctors were trained to dismiss symptoms as “tough it out” or prescribe antidepressants instead. - Starting HRT within ~10 years of menopause (ideally ~50) maximizes benefits and safety; after ~60, the risk-benefit shifts. Makary: This was dogma, not data — and it cost women decades of health. The tide is turning. Are you (or someone you know) reconsidering HRT after this? Raw, no-filter truth about one of the largest medical reversals in history
5:46

FDA Commissioner Dr. Marty Makary calls the demonization of hormone replacement therapy (HRT) for postmenopausal women “the biggest screw-up of modern medicine.” Key points from his explosive take: - A misinterpreted 2002 NIH study (led by a Fauci-like figure) claimed HRT causes breast cancer — but the increase was not statistically significant, and no subsequent study has shown increased breast cancer mortality. - Women were scared off a treatment that dramatically improves quality of life and extends life. - Benefits include: - 25–50% lower risk of fatal heart attacks (leading killer in women) - ~90% reduction in osteoporosis risk - Prevention of cognitive decline - Relief from severe symptoms lasting ~8 years on average (hot flashes, night sweats, mood swings, painful sex, weight gain) - Marriages have been saved, lives improved — yet doctors were trained to dismiss symptoms as “tough it out” or prescribe antidepressants instead. - Starting HRT within ~10 years of menopause (ideally ~50) maximizes benefits and safety; after ~60, the risk-benefit shifts. Makary: This was dogma, not data — and it cost women decades of health. The tide is turning. Are you (or someone you know) reconsidering HRT after this? Raw, no-filter truth about one of the largest medical reversals in history

Camus

107,192 Aufrufe • vor 6 Monaten

What about when a man who had his penis inverted has complications from a surgery he chose to have on his healthy male genitalia? How is he not an unnecessary burden on the health system? And it isn't "hrt" for ♂️
1:10

What about when a man who had his penis inverted has complications from a surgery he chose to have on his healthy male genitalia? How is he not an unnecessary burden on the health system? And it isn't "hrt" for ♂️

No°

19,430 Aufrufe • vor 3 Monaten

It’s been more than 20 years since media headlines about the Women’s Health Initiative study incorrectly linked HRT to an increased risk of breast cancer, but even today many women still avoid HRT because of perceived breast cancer fears. This misinformation is really damaging to women’s health, so on my podcast this week I invited Dr Avrum Bluming to join me. Avrum is a leading US oncologist and has spent 25 years studying the benefits and risks of HRT in breast cancer survivors. As you’ll hear in the episode, Avrum tells me about more recent studies that have shown that oestrogen alone decreases the risk of breast cancer development by 23% and the risk of death from breast cancer by 40%. Yet many people still do not realise this. It is so important that everyone knows the real story about the WHI study and the misreporting of the data so I really would recommend listening to the full episode:
0:52

It’s been more than 20 years since media headlines about the Women’s Health Initiative study incorrectly linked HRT to an increased risk of breast cancer, but even today many women still avoid HRT because of perceived breast cancer fears. This misinformation is really damaging to women’s health, so on my podcast this week I invited Dr Avrum Bluming to join me. Avrum is a leading US oncologist and has spent 25 years studying the benefits and risks of HRT in breast cancer survivors. As you’ll hear in the episode, Avrum tells me about more recent studies that have shown that oestrogen alone decreases the risk of breast cancer development by 23% and the risk of death from breast cancer by 40%. Yet many people still do not realise this. It is so important that everyone knows the real story about the WHI study and the misreporting of the data so I really would recommend listening to the full episode:

Dr Louise Newson

40,567 Aufrufe • vor 2 Jahren

The potential benefits of hormone replacement therapy for women have been in the bucket of things that modern medicine has underappreciated, underrecognized, and underfunded. Women need to know the real data on this topic – not dogma.
1:23

The potential benefits of hormone replacement therapy for women have been in the bucket of things that modern medicine has underappreciated, underrecognized, and underfunded. Women need to know the real data on this topic – not dogma.

Dr. Marty Makary

748,354 Aufrufe • vor 1 Jahr

For more than two decades, the American medical establishment turned its back on women. Millions of women were told to fear the very therapy that could have given them strength, peace, and dignity through one of life’s most difficult transitions—menopause. That ends today. The FDA is initiating the removal of broad “black box” warnings from hormone replacement therapy products for menopause.
1:22

For more than two decades, the American medical establishment turned its back on women. Millions of women were told to fear the very therapy that could have given them strength, peace, and dignity through one of life’s most difficult transitions—menopause. That ends today. The FDA is initiating the removal of broad “black box” warnings from hormone replacement therapy products for menopause.

Secretary Kennedy

389,275 Aufrufe • vor 10 Monaten

For most women, the benefits of taking body identical HRT far outweigh any risks. Yet many are reluctant to take it and many doctors are also reluctant to prescribe it. This is usually due to a false belief that HRT is too risky and causes breast cancer. I am sharing with you this paper that has recently been published looking at oestrogen-only HRT and breast cancer incidence. The paper is a meta-analysis, which is a type of statistical analysis where researchers review, combine, and analyse multiple studies together. In this paper, researchers have looked at randomised studies involving oestrogen and breast cancer incidence and put them together to see what the results show. The conclusion is clear: women who take oestrogen-only HRT have a LOWER future risk of developing breast cancer. We’ve known for several years that women who take oestrogen have a lower future incidence of breast cancer as well as other cancers and other conditions. This paper is very reassuring, and it’s worth remembering that any risk of breast cancer has been shown using oestrogen with a combination of a synthetic progestogen, not the body-identical type progesterone healthcare professionals usually prescribe.
1:31

For most women, the benefits of taking body identical HRT far outweigh any risks. Yet many are reluctant to take it and many doctors are also reluctant to prescribe it. This is usually due to a false belief that HRT is too risky and causes breast cancer. I am sharing with you this paper that has recently been published looking at oestrogen-only HRT and breast cancer incidence. The paper is a meta-analysis, which is a type of statistical analysis where researchers review, combine, and analyse multiple studies together. In this paper, researchers have looked at randomised studies involving oestrogen and breast cancer incidence and put them together to see what the results show. The conclusion is clear: women who take oestrogen-only HRT have a LOWER future risk of developing breast cancer. We’ve known for several years that women who take oestrogen have a lower future incidence of breast cancer as well as other cancers and other conditions. This paper is very reassuring, and it’s worth remembering that any risk of breast cancer has been shown using oestrogen with a combination of a synthetic progestogen, not the body-identical type progesterone healthcare professionals usually prescribe.

Dr Louise Newson

23,788 Aufrufe • vor 2 Jahren

This video is worth watching - a human heart made by some of the incredible women I met last week in Australia The commonest cause of death in women’s cardiovascular disease (CVD) and women taking HRT can have a 50% reduction in CVD and a 30% reduction in death from heart disease yet only around 4-6% of menopausal women globally take HRT Too many menopausal women are neglected. So much needs to change
0:24

This video is worth watching - a human heart made by some of the incredible women I met last week in Australia The commonest cause of death in women’s cardiovascular disease (CVD) and women taking HRT can have a 50% reduction in CVD and a 30% reduction in death from heart disease yet only around 4-6% of menopausal women globally take HRT Too many menopausal women are neglected. So much needs to change

Dr Louise Newson

13,319 Aufrufe • vor 2 Jahren

Recently I delivered a talk to 250 healthcare professionals who work in mental health teams to highlight the role of our hormones in relation to our mental health. As you’ll hear in this clip, we have oestrogen and testosterone receptors all over our bodies and in our brain as well. Each area of the brain plays a role in the way we think, the way we move and the way we act, and so when our hormone levels reduce, many women will experience psychological symptoms too. It’s really important that our hormones are considered when women are struggling with their mental health, so receiving this feedback from the consultant psychiatrist who organised the event is really good to see: “I must say I think we will all consider the menopause much more in our clinical practice after yesterday, I am keen to see if we can get some agreement or guidance around this and how we can potentially advise GP colleagues to consider HRT treatment if they have not done so already. I certainly will be suggesting it in my practice.” Thank you to Kehinde for organising the event with Nottinghamshire Healthcare Nottinghamshire Healthcare Medical Education . Hopefully we will see an improvement in mental health support for perimenopausal and menopausal women as a result.
0:43

Recently I delivered a talk to 250 healthcare professionals who work in mental health teams to highlight the role of our hormones in relation to our mental health. As you’ll hear in this clip, we have oestrogen and testosterone receptors all over our bodies and in our brain as well. Each area of the brain plays a role in the way we think, the way we move and the way we act, and so when our hormone levels reduce, many women will experience psychological symptoms too. It’s really important that our hormones are considered when women are struggling with their mental health, so receiving this feedback from the consultant psychiatrist who organised the event is really good to see: “I must say I think we will all consider the menopause much more in our clinical practice after yesterday, I am keen to see if we can get some agreement or guidance around this and how we can potentially advise GP colleagues to consider HRT treatment if they have not done so already. I certainly will be suggesting it in my practice.” Thank you to Kehinde for organising the event with Nottinghamshire Healthcare Nottinghamshire Healthcare Medical Education . Hopefully we will see an improvement in mental health support for perimenopausal and menopausal women as a result.

Dr Louise Newson

40,929 Aufrufe • vor 3 Jahren

As many of you know, women who take HRT and still have their womb are required to take a type of progestogen, in addition to oestrogen. This is because, over time, taking oestrogen can lead to a build­up in the lining of your womb. When it comes to progestogen doses, as with all HRT, there is no one-size-fits-all approach to this, and it is important it's individualised based on your specific needs and symptoms. I talk more about this in this video. It is of course worth stressing that if you do have any concerns about vaginal bleeding, go get advice from your clinician.
1:16

As many of you know, women who take HRT and still have their womb are required to take a type of progestogen, in addition to oestrogen. This is because, over time, taking oestrogen can lead to a build­up in the lining of your womb. When it comes to progestogen doses, as with all HRT, there is no one-size-fits-all approach to this, and it is important it's individualised based on your specific needs and symptoms. I talk more about this in this video. It is of course worth stressing that if you do have any concerns about vaginal bleeding, go get advice from your clinician.

Dr Louise Newson

26,850 Aufrufe • vor 2 Jahren