How does the brain work? Scientists are closer to the answer with the largest wiring diagram and functional map of a mammalian brain to date. 🧵

A cubic millimeter may not sound like much, but it is a big step in neuroscience. ~4km of axons were mapped – the length of Central Park – together with live imaging data, from a piece of brain tissue the size of a grain of sand in this landmark release.

This was previously thought to be impossible - and teamwork made it happen. 🧠 @BCMFromtheLabs collected live brain imaging 🔬 @AllenInstitute sectioned & imaged that tissue in high res 💻 @PrincetonNeuro reconstructed in 3D

One of the most surprising findings is that inhibitory cells are highly selective and even work together to suppress the activity of other brain cells. Read the study:

This data can also be accessed on the MICrONS Explorer – a growing portal for connectivity and functional imaging data. Dive into the data: New to MICrONS? Check out these tutorials:

The collaborative, global effort was made possible by support from @IARPAnews and @NIH's Brain Research Through Advancing Innovative Neurotechnologies® Initiative, or The BRAIN Initiative®. #studyBRAIN

Transform health with functional medicine! Join IFM in San Diego to explore the latest clinical research from the field.

We are also CLOSER to the Andromeda Galaxy every single day, with an imminent collision in … only 4.5 Billion years!

Insane work-

how does it work what’s it thinking?

Beautiful

@TweetHelperBot download this video, please. 🙏