In a recent overnight imaging session, I made a startling discovery... COS7 throw midnight dance parties. Who knew? These party animals are dressed in Vimentin-TagGFP (orange) and the ER marker SnapTag-Sec61b (blue) #FluorescenceFriday

Love it! When COS7 cells dance, what music are they dancing to?

That's one of the unsolved mysteries of the universe. I guess I'll need a micro *phone* on my micro *scope*

@WildPersistence Better than disco!

Very pretty? I plan to visit @HHMIJanelia next Wed. I would love to chat about your science and the imaging side of your work.

@HHMIJanelia I'd love that! I'll be around all day.

@christlet Stunning 🤩🤩🤩

This is wonderful. Really. There is a lot here we need to start seeing, it feels.

Wow 😮 Missed opportunity to overlay this with Sandstorm by Darude..

Very cool! Do you ever have bundling/clumping of vim filaments? I’ve had issues with most constructs in Jurkats and I wonder if it’s a cell line/type issue

Depends a lot on the fusion that you use. Many (especially n term tagged) form weird networks. Expression levels of endogenous and exogenous vimentin can also have a big effect (which would vary by cell line and transfection/transduction technique)