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🧬 Introducing Longevity Vaccines. Building on experience from the Rentosertib program, Insilico’s new research initiative extends its strategy of tackling both disease and biological aging into preventive cell clearing. 🛡️ Combining AI and circular mRNA, the approach aims to equip the body’s own T cells to remove selected aging... show more

Insilico Medicine

15,427 subscribers

72,191 views • 7 days ago •via X (Twitter)

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15 Comments

Mgoes (bio/acc 🤖💉)7 days ago

rentosertib was a lung drug that happened to move an aging clock now there's a longevity vaccine program. the pipeline is downstream of a post-hoc analysis and everyone's cool with it

ProgressBureau7 days ago

More healthy years mean more chances to learn, begin again and stay close to the people we love. If we can prevent some of the damage of aging, we give people more freedom over their own lives. That is a future worth building.

Whatever — e/acc7 days ago

Biology is getting so cool. Literally reprogramming our meat computers.

George Frukenmiller7 days ago

🚀🚀

EyeCoin7 days ago

Clearing senescent immune cells could protect more than lifespan aging doesn’t spare the eyes. Strong direction.

[email protected]7 days ago

This is exciting! Fibrious in Lipedema is another market whose upside would be massive. Something like 10 % of all woman are suffering with it. There are no treatments apart from removal surgery, costing thousands $$. It'd be great to test the drugs effectiveness on this disease.

🇺🇦🇮🇱Путина нужно судить7 days ago

Please hurry 🙄

Mark7 days ago

@grok чья это компания страна кто добился этого ?

Pavel Zun7 days ago

Okay, yeah, when do you plan to roll it out to the clinic and how much will it cost?

KickWestra7 days ago

Make it mainstream pls.

🇺🇦🇮🇱Путина нужно судить7 days ago

@grok please tell me me more in great detail.

PEB977 days ago

Lfg

P.D. Petro 𝕏 🎸🤠🇺🇸7 days ago

👍🏻

Cory Kornowicz7 days ago

So these are just CAAR-T cell therapies?

Joe Williams7 days ago

Oh please YES

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63,172 views • 10 months ago

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Dr. Patrick Soon-Shiong on the Cancer-Fighting Immune Breakthrough: Awakening the 450 Million-Year-Old Natural Killer Cell After decades of pioneering work since discovering the natural killer cell in the 1990s—a remarkable immune cell created by God and preserved through 450 million years—Dr. Patrick Soon-Shiong reveals an extraordinary breakthrough. This cell, unknown to many until the 1970s, serves as the body's first line of defense, designed to destroy cancer cells, infections like COVID, sepsis, bacteria, and fungus. Dr. Soon-Shiong emphasizes that this is not an invention, but an enlightenment: activating the body’s own natural killer cells to combat disease naturally, shifting away from toxic chemotherapy and radiation. With a single jab, they have unlocked the secret to empowering this primal cellular protector. This is evolution’s own weapon against illness, a game-changer that taps into ancient biology to revolutionize modern medicine. This insight reframes how we think about health and cancer treatment by harnessing the immune system's innate power, moving beyond harsh treatments, and embracing nature’s original disease-fighter from within. The discovery is a call to awaken the body’s own god-given defense system for a future of empowered healing.

Camus

33,407 views • 10 months ago

We were told the shot stays in your arm. It doesn’t. The mRNA is wrapped in tiny fat bubbles. Those bubbles leak out of the muscle and travel through your blood. Almost every cell in your body has a fatty coating, so the bubbles get swallowed by whatever cells they bump into — heart cells, liver cells, brain cells, reproductive organs. Once inside, the cell reads the message and starts making a piece of the virus. Your immune system sees one of your own cells pumping out a foreign protein and assumes the cell is infected. So it kills it. There’s no “only go to muscle cells” instruction. Which organs get hit is mostly luck. That’s the real design problem — not just the spike protein, but a delivery system that turns random cells into targets. That’s why critics call it a flawed platform. Until they can aim these fat bubbles at the right cells and keep them there, every new version carries the same basic risk.

We were told the shot stays in your arm. It doesn’t. The mRNA is wrapped in tiny fat bubbles. Those bubbles leak out of the muscle and travel through your blood. Almost every cell in your body has a fatty coating, so the bubbles get swallowed by whatever cells they bump into — heart cells, liver cells, brain cells, reproductive organs. Once inside, the cell reads the message and starts making a piece of the virus. Your immune system sees one of your own cells pumping out a foreign protein and assumes the cell is infected. So it kills it. There’s no “only go to muscle cells” instruction. Which organs get hit is mostly luck. That’s the real design problem — not just the spike protein, but a delivery system that turns random cells into targets. That’s why critics call it a flawed platform. Until they can aim these fat bubbles at the right cells and keep them there, every new version carries the same basic risk.

Dr. Dawn Michael

51,409 views • 1 day ago

Scientists just figured out how to reverse aging using AI. And this is a massive breakthrough. We can now reprogram any human cell back to age 20. Heart cells, brain cells, skin cells, all reset to their biological prime. And here’s the wildest part…the technology to do this, has already existed since 2012 (it won the Nobel Prize). But the real breakthrough wasn’t possible until this year, when they supercharged it with AI. It’s a wild story. So in 2006, scientists discovered Yamanaka factors. They’re proteins that can basically convert any normal cell into a universal stem cell. Now this was a huge deal, because these stem cells are basically like magic healers. If you have torn muscle tissue, you could inject these stem cells into the area and they will turn into the youthful muscle cells you need. So Yamanaka factors were this insane breakthrough, because they allowed any human to turn any cell you already have into these magic healers. But, there was one big problem… It turns out, the original Yamanaka factors weren’t very good at this stem cell conversion. They could do it, but they just weren’t very reliable. Enter OpenAI...and this is where things get crazy. OpenAI designed a special AI model built specifically to create new proteins. Think of it like ChatGPT but for protein engineering. So they took all the Yamanaka research and asked this new AI to go ham on improving it. And get this… Their version was 50x more effective than the original. They tested it on 50 year old cells and it successfully started repairing 30% of their cells in just 7 days. This is just science fiction…it actually happened. And it sounds crazy, but in a few years, humans will be able to take a shot that will literally reverse the age of their cells.

Scientists just figured out how to reverse aging using AI. And this is a massive breakthrough. We can now reprogram any human cell back to age 20. Heart cells, brain cells, skin cells, all reset to their biological prime. And here’s the wildest part…the technology to do this, has already existed since 2012 (it won the Nobel Prize). But the real breakthrough wasn’t possible until this year, when they supercharged it with AI. It’s a wild story. So in 2006, scientists discovered Yamanaka factors. They’re proteins that can basically convert any normal cell into a universal stem cell. Now this was a huge deal, because these stem cells are basically like magic healers. If you have torn muscle tissue, you could inject these stem cells into the area and they will turn into the youthful muscle cells you need. So Yamanaka factors were this insane breakthrough, because they allowed any human to turn any cell you already have into these magic healers. But, there was one big problem… It turns out, the original Yamanaka factors weren’t very good at this stem cell conversion. They could do it, but they just weren’t very reliable. Enter OpenAI...and this is where things get crazy. OpenAI designed a special AI model built specifically to create new proteins. Think of it like ChatGPT but for protein engineering. So they took all the Yamanaka research and asked this new AI to go ham on improving it. And get this… Their version was 50x more effective than the original. They tested it on 50 year old cells and it successfully started repairing 30% of their cells in just 7 days. This is just science fiction…it actually happened. And it sounds crazy, but in a few years, humans will be able to take a shot that will literally reverse the age of their cells.

Whiplash347

68,643 views • 10 months ago