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Learn how Toyota is leveraging Flutter to revolutionize their infotainment system 🚘🩵 Chapters: 1:09 - Why Toyota chose Flutter 2:22 - Leveraging Flutter developer tools 3:31 - Looking Ahead: The 2027 Highlander BEV

18,507 görüntüleme • 3 ay önce •via X (Twitter)

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New episode featuring Stanford professor, neurobiologist, and host of the incredibly popular Huberman Lab Podcast, Dr. Andrew Huberman (Andrew D. Huberman, Ph.D.). What makes Andrew truly exceptional is his ability to translate scientific findings into practical, actionable advice, enabling listeners to leverage new understandings of biology and neurobiology to improve their lives. In this episode, Dr. Huberman showcases his truly immense knowledge of the brain's dopamine system, which is incredibly central to many modern issues of motivation and attention that many of us struggle with. The public perception of Dr. Huberman's work often focuses on his unique distillations of protocols, but what I particularly enjoyed about this conversation was finding a common thread: the benefit of having an essential life philosophy of valuing "hard effort" over outcomes, something Andrew refers to as "forward center of mass." This podcast explains down to a neurobiological level why embracing discomfort can activate our motivation circuits, elevate dopamine and other catecholamine levels, and retrain brain regions like the anterior midcingulate cortex, ultimately growing our capacity for effort and striving at a fundamental level. A big thank you to Andrew for equipping us with this knowledge, enabling us to apply these insights for individual personal and professional growth. This episode is available on X, YouTube, Spotify, and everywhere else. Links in comment. Timestamps: 0:00 - Introduction 2:37 - The neuromodulatory role of dopamine 4:29 - Driver of motivation vs. experiencing reward 9:35 - Why dopamine dynamics act as a "wave pool" 13:15 - Why dopamine neurons need a recovery period 18:32 - Why dopamine peaks without effort are dangerous 21:52 - The number one sign of a highly motivated individual 23:59 - Dopamine reward-prediction error 26:18 - How effort and anticipation influence dopamine release 28:21 - Does lacking motivation reflect dopamine system deficits? 33:00 - Why motivation has a 'warm-up' period 37:16 - Why to attach reward to effort itself 47:51 - Tips for fostering tenacity in children 50:05 - Visualization of negative outcomes (why to do it) 52:51 - How to overcome procrastination 58:51 - How exercise affects the dopamine system 1:03:35 - Cold exposure vs. drug highs 1:05:29 - The entrainment effect of same-time exercise 1:09:24 - Why you shouldn't rely on stimulants 1:16:52 - "Counting walls" during deliberate cold exposure 1:21:44 - Cold exposure parameters for increasing dopamine 1:24:18 - Cold plunge alternatives for replenishing dopamine 1:25:35 - Why Andrew limits most workouts to 80-85% intensity 1:28:37 - Using exercise & cold exposure as stimuli for the brain 1:31:08 - Why "hard efforts" retrain the brain to overcome 1:33:31 - tMS and ultrasound as neuromodulatory therapies 1:36:22 - What does Dr. Huberman think of Neuralink? 1:38:02 - Advantages of neuromodulation over pharmacotherapy 1:39:28 - Why non-sleep deep rest may replenish dopamine 1:49:45 - My experience trying NSDR after poor sleep 1:51:04 - The ‘body still, mind active’ state for creativity 1:54:15 - How to cultivate a healthy relationship with social media 2:00:44 - The unique psychosocial dynamics of X (formerly Twitter) 2:02:05 - Andrew's recommended daily use limit for Instagram 2:04:09 - Does Lex Fridman have a symbiotic relationship with X? 2:04:39 - Is screen time increasing the prevalence of ADHD? 2:06:20 - Why Andrew recommends setting social media constraints 2:09:32 - Is social media increasing divorce rates? 2:12:12 - How low solar angle sunlight affects the circadian rhythm 2:22:10 - Limiting the adverse effects of late-night artificial light 2:23:57 - The light bulb that mimics sunrise and sunset 2:25:09 - How to spike morning cortisol by 50% (and why that's good) 2:26:21 - What's the optimal time to view morning sunlight? 2:27:11 - Can light panels replace morning sunlight? 2:28:33 - Combatting laptop & phone use with long distance viewing 2:30:00 - Why two hours outdoors daily may prevent myopia 2:35:06 - Why Andrew recommends limiting alcohol to 0-2 drinks per week 2:43:09 - How alcohol affects the dopamine and serotonin systems 2:48:47 - Treating ADHD with drugs, supplements, & behaviors 2:53:30 - Why studies on school start age suggest ADHD is overdiagnosed 3:00:00 - Andrew's weekly workout routine 3:13:14 - Why a disciplined life is not a deprived life 3:05:43 - Andrew's diet & why his dinners are higher in carbs 3:06:39 - The science of the physiological sigh3:07:34 - Andrew's supplement routine 3:10:00 - Andrew's experimentation with peptides 3:15:10 - How Andrew processes sometimes negative feedback 3:20:30 - The volatility of interacting with internet crowds

Dr. Rhonda Patrick

334,168 görüntüleme • 2 yıl önce

The enemy of sleep is effort. In this episode, Dr. Michael Grandner (Dr. Michael Grandner) explains how insomnia fundamentally stems from a learned pattern of wakefulness and why, for many, the bed itself becomes a source of stress and vigilance rather than rest. We explore practical strategies to retrain your brain to effortlessly anticipate sleep rather than forcing it. Dr. Grandner also highlights why sleep apnea is shockingly prevalent yet frequently undetected, and provides effective treatment alternatives beyond CPAP. Additionally, we discuss how supplements and other substances influence sleep architecture, how to optimize sleep tracking devices, and how to strategically use sleep to enhance cognitive and physical performance. This is an essential podcast for anyone looking to improve their sleep. Links in the comments. Timestamps: 0:00 - Introduction 1:33 - Insomnia vs. poor sleep 3:59 - Does stressing worsen insomnia? 10:28 - Why CBT-I targets wakefulness 12:59 - Reserving bed strictly for sleep 17:11 - Can trying too hard backfire? 18:26 - A fix for nighttime scrolling 21:47 - Can't fall back asleep? Get up 24:39 - Why effort keeps you awake 26:18 - Sleep restriction therapy 28:57 - How to fall asleep faster 31:39 - Avoiding bedtime cliffhangers 33:20 - Sedatives vs. CBT-I 37:33 - Insomnia by the numbers 38:54 - Why sleep apnea is so common 42:31 - Nighttime waking & sleep apnea 48:37 - At-home apnea tests 50:10 - What causes sleep apnea? 52:52 - Sleep stages 1:01:20 - Why do we dream? 1:05:38 - Apnea destroys sleep architecture 1:07:07 - Sleep apnea & Alzheimer’s risk 1:10:07 - Poor sleep, attention & memory 1:13:23 - CPAP alternatives 1:17:26 - Mouth taping 1:19:30 - Measuring apnea treatment success 1:21:33 - Sleep hygiene for chaotic schedules 1:25:00 - Do blue-blockers enhance sleep? 1:25:46 - Why morning light matters 1:30:33 - Should you delay morning coffee? 1:34:30 - Consistent mornings vs. bedtimes 1:38:01 - Revenge bedtime procrastination 1:42:49 - Is 5 mg melatonin too much? 1:50:25 - Are melatonin labels misleading? 1:53:19 - Melatonin & immune system boost 1:54:14 - Melatonin safety myths 1:58:35 - Magnesium, glycine, & L-theanine 2:01:37 - Glutamine & B12 disrupt sleep 2:03:08 - THC & REM sleep 2:09:36 - Does CBD help? 2:12:09 - Alcohol as a sleep aid 2:15:06 - How late is too late for caffeine? 2:19:19 - Staying up late & unhealthy eating 2:24:09 - Is shift work worse than smoking? 2:27:51 - Ideal power nap length 2:29:38 - Napping advice for shift workers 2:32:18 - How to beat jet lag 2:40:22 - Do trackers detect wakefulness? 2:43:56 - Sleep stage tracking accuracy 2:48:24 - Wearable sleep scores 2:57:56 - Evening habits elevating heart rate 2:59:59 - Insufficient REM & deep sleep 3:02:55 - Orthosomnia from sleep trackers 3:07:12 - Better sleep & cognitive resilience 3:09:42 - School start times vs. teen biology 3:14:26 - A sleep hack for athletes 3:16:36 - Sleep banking before competition 3:19:03 - Poor sleep & injury risk 3:24:00 - Why caffeine can't fix poor sleep 3:25:38 - Eye masks & earplugs 3:27:15 - Proven ways to fall asleep faster 3:29:11 - Reading before bed 3:30:02 - Algorithm for falling back asleep 3:31:04 - Proven strategy for deeper sleep 3:32:27 - Reducing nighttime urination 3:34:11 - Does sharing a bed disrupt sleep? 3:35:50 - Are you sleeping enough? 3:37:28 - Do you really need 8 hours? 3:38:42 - Adjusting to your chronotype

Dr. Rhonda Patrick

192,656 görüntüleme • 11 ay önce

I sat down with Nicolas Sharp, founder of Attio, to talk in depth about how his company is disrupting the $80 billion CRM market. Attio has raised $116m, is 4x'ing ARR and is one of the fastest growing companies in Europe. We talk about: - Why Attio went against all conventional wisdom and spent years 3 years building the product before launching - Why Attio doesn’t hire ‘Software Engineers’ and who they hire instead. - How Attio chose investors who would back a long-term bet against multi-billion $ incumbents - How Attio is building CRM from first principles for the AI era - Who should you avoid hiring at all costs, and who should you hire for your startup And so much more. If you’re interested in learning about the story of how Nick built Attio into the incredible company it is today and is disrupting one of the most important software categories, you’re going to want to see this. Enjoy // Timestamps 00:00 Intro 00:39 Why Attio spent 3 years building their product before launch 5:05 The Power of Building Systems, Not a Box of Features 9:05 How to know when it’s time to launch 13:30 Nick’s Playbook For a Killer Product Launch 18:09 How To Go From an Investor to a Founder 23:05 How Failure Led to Attio's Big Break 28:07 Why startups need to hire "Hidden Gems," 34:05 Fundraising 49:36 Why Attio Invests In Inexperienced Talent 55:07 The Case For Not Hiring Software Engineers (& Who You Should Hire Instead) 1:02:46 The 8 Persona Hiring Framework 1:09:05 How Attio doesn’t use OKR's 1:27:11 Where does Nick's Ambition and Grit come from? 1:36:59 How Attio is Building CRM from First Principles for the AI era 1:45:29 How to Successfully Market In A Crowded Industry 1:51:10 Breaking Down Attio’s Viral Marketing Strategies 2:02:15 The Change That Had The Biggest Impact on Customer Conversion 2:05:04 Why Attio created A “Reverse Trial” 2:10:16 Why Nick is building from London, not Silicon Valley 2:22:48 The 10-Year Vision for Attio

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26,369 görüntüleme • 11 ay önce