Loading video...

Video Failed to Load

There was a problem loading this video. This could be due to a temporary network issue or the video might be unavailable.

Neural population dynamics in mouse motor cortex during voluntary gait modification. Neuropixels 2.0 is really a game-changer for resolving single-trial dynamics in a freely-moving prep. Check out Eric Kirk’s poster at SfN for more details …

Britton Sauerbrei

3,451 subscribers

19,802 views • 2 years ago •via X (Twitter)

Health & Wellness Science & Technology

Anya Rossi• Live Now

Private livecam show

8 Comments

Jianing Yu2 years ago

Cool demo! Why does the contral-trail type drive MC eariler than the contral-lead type in PC1/2? I thought the mouse lifts contral paw first in the later contral-lead type?

Britton Sauerbrei2 years ago

Great question! The data in both conditions are aligned to swing onset for the contralateral limb. While there are certainly neurons (like this one) that fire during cFL swing over the obstacle, the dominant signal in PC 1-2 is synchronized with swing in the *leading* limb.

Dan Butler2 years ago

Looks interesting - is there a link to read more?

Britton Sauerbrei2 years ago

Thanks! Not yet, but stay tuned …

GG🌱2 years ago

wow, it looks cool! I will let my team to visit the Eric Kirk's poster!

Mackenzie Mathis, PhD2 years ago

DLC still? Beautiful work 🥳

Britton Sauerbrei2 years ago

Thanks, Mackenzie! Yep - DLC + Anipose are the backbone of our tracking pipeline, and they work beautifully!

Dr Rob Leigh2 years ago

@JohnRHutchinson @CathalMcCrory1

Related Videos

Implemented a visualization for the neural network today. This is a neural network being trained to learn the snake game in a terminal. It's built in Rust using Ratatui More input details in thread

Implemented a visualization for the neural network today. This is a neural network being trained to learn the snake game in a terminal. It's built in Rust using Ratatui More input details in thread

Bones

165,715 views • 2 years ago

We just broke (exploded) ground on the single largest economic investment in Mississippi’s history. The 2.5 billion dollar investment from Steel Dynamics will create 1,000 jobs with an average salary of $93,000. This is a game changer for Mississippi!

We just broke (exploded) ground on the single largest economic investment in Mississippi’s history. The 2.5 billion dollar investment from Steel Dynamics will create 1,000 jobs with an average salary of $93,000. This is a game changer for Mississippi!

Governor Tate Reeves

127,476 views • 3 years ago

The new MLM2 is a game changer. ✅ it out for yourself or the golfers in your life. Exclusive deals at for a few more days until Dec 10

The new MLM2 is a game changer. ✅ it out for yourself or the golfers in your life. Exclusive deals at for a few more days until Dec 10

Claude Harmon III

11,563 views • 2 years ago

DexNDM — a neural dynamics model for dexterous hands Galbot, Tsinghua University and Shanghai Qizhi Institute released DexNDM, a neuromuscular-style dynamics model for dexterous hands. The team reports it reduces reliance on large sets of flawless demonstrations: using biased real-world data, DexNDM bridges Sim→Real for in-hand rotations across arbitrary poses and axes, handling slender, tiny, and irregular objects. Developers say the method is moving from lab validation toward production-ready workflows.

DexNDM — a neural dynamics model for dexterous hands Galbot, Tsinghua University and Shanghai Qizhi Institute released DexNDM, a neuromuscular-style dynamics model for dexterous hands. The team reports it reduces reliance on large sets of flawless demonstrations: using biased real-world data, DexNDM bridges Sim→Real for in-hand rotations across arbitrary poses and axes, handling slender, tiny, and irregular objects. Developers say the method is moving from lab validation toward production-ready workflows.

RoboHub🤖

34,445 views • 10 months ago

Introducing Continuous Thought Machines New Blog: Modern AI is powerful, but it’s still distinct from human-like flexible intelligence. We believe neural timing is key. Our Continuous Thought Machine is built from the ground up to use neural dynamics as a powerful representation for intelligence. Thought takes time, and reasoning is a process. Biological brains inspire us with their complex neural activity, where neural timing is critical to intelligence. We’re exploring how to bring that power to AI. The Continuous Thought Machine (CTM) incorporates neuron-level temporal processing and neural synchronization, moving beyond current AI limitations. Our approach has two core innovations: (1) neuron-level temporal processing, where each neuron uses unique parameters to process a history of incoming signals for fine-grained temporal dynamics, and (2) neural synchronization, used as a direct latent representation to modulate data and produce outputs, encoding information directly in the timing of neural activity. Learn more about our approach: Interactive Report: Full Paper: GitHub :

Introducing Continuous Thought Machines New Blog: Modern AI is powerful, but it’s still distinct from human-like flexible intelligence. We believe neural timing is key. Our Continuous Thought Machine is built from the ground up to use neural dynamics as a powerful representation for intelligence. Thought takes time, and reasoning is a process. Biological brains inspire us with their complex neural activity, where neural timing is critical to intelligence. We’re exploring how to bring that power to AI. The Continuous Thought Machine (CTM) incorporates neuron-level temporal processing and neural synchronization, moving beyond current AI limitations. Our approach has two core innovations: (1) neuron-level temporal processing, where each neuron uses unique parameters to process a history of incoming signals for fine-grained temporal dynamics, and (2) neural synchronization, used as a direct latent representation to modulate data and produce outputs, encoding information directly in the timing of neural activity. Learn more about our approach: Interactive Report: Full Paper: GitHub :

Sakana AI

290,087 views • 1 year ago

It's official! As revealed today at LRG3, the next Shantae game is currently in development. We'll have more details in the future, but for now, please check out this statement from series director Matt Bozon.

It's official! As revealed today at LRG3, the next Shantae game is currently in development. We'll have more details in the future, but for now, please check out this statement from series director Matt Bozon.

WayForward

581,919 views • 10 months ago

The story event "Make a Splash! Summer Showdown! ☆" is set to begin at 10:00 p.m., Jul 2 (UTC)! Stay tuned for an event-exclusive story! For more details, please check the in-game notice. #Umamusume

The story event "Make a Splash! Summer Showdown! ☆" is set to begin at 10:00 p.m., Jul 2 (UTC)! Stay tuned for an event-exclusive story! For more details, please check the in-game notice. #Umamusume

Umamusume: Pretty Derby

543,792 views • 2 months ago

The story event "Hungry for a Miracle" is now available! Get event-exclusive Support Cards as rewards for progressing through the story! For more details, please check the in-game notice. #Umamusume

The story event "Hungry for a Miracle" is now available! Get event-exclusive Support Cards as rewards for progressing through the story! For more details, please check the in-game notice. #Umamusume

Umamusume: Pretty Derby

129,601 views • 8 months ago

A children’s hospice in Liverpool called @ZoesPlaceLiv needs urgent help! Just Giving link is below or check out Adam Rowe page for more details #zoesplace

A children’s hospice in Liverpool called @ZoesPlaceLiv needs urgent help! Just Giving link is below or check out Adam Rowe page for more details #zoesplace

Troy Hawke

150,462 views • 1 year ago

AGE 1000 is a brand new game project set in the Dragon Ball universe and is set to release in 2027. Check out the announcement trailer and be on the lookout for more details to come at Dragon Ball Games Battle Hour on April 18-19, 2026.

IGN

63,455 views • 7 months ago

Excited to share that our work NeuralActuator: Neural Actuation Modeling for Robot Dynamics and External Force Perception has been accepted to #RSS2026! Your robot — even a low-cost one — can feel external forces without torque or tactile sensors. TL;DR: NeuralActuator is a neural actuator model that jointly predicts 1️⃣torque to capture the nonlinear and time-varying current–to–torque relationship of low-cost servos, 2️⃣external contact forces (and force detection gates) for sensorless force perception, 3️⃣and motor conditions that indicate each motor’s operating regime. Here is a fast-forward video clip ⬇️ We are also covering more robots like LeRobot-S101 and Franka Panda. More details coming soon.

Excited to share that our work NeuralActuator: Neural Actuation Modeling for Robot Dynamics and External Force Perception has been accepted to #RSS2026! Your robot — even a low-cost one — can feel external forces without torque or tactile sensors. TL;DR: NeuralActuator is a neural actuator model that jointly predicts 1️⃣torque to capture the nonlinear and time-varying current–to–torque relationship of low-cost servos, 2️⃣external contact forces (and force detection gates) for sensorless force perception, 3️⃣and motor conditions that indicate each motor’s operating regime. Here is a fast-forward video clip ⬇️ We are also covering more robots like LeRobot-S101 and Franka Panda. More details coming soon.

Zhiyang (Frank) Dou

50,886 views • 4 months ago

The story event "Make a Splash! Summer Showdown! ☆" is now available! Get event-exclusive Support Cards as rewards for progressing through the story! For more details, please check the in-game notice. #Umamusume

The story event "Make a Splash! Summer Showdown! ☆" is now available! Get event-exclusive Support Cards as rewards for progressing through the story! For more details, please check the in-game notice. #Umamusume

Umamusume: Pretty Derby

109,533 views • 2 months ago

Introducing Quad Cortex mini Quad Cortex mini delivers the full Quad Cortex experience in our most compact, usable format yet, without cutting corners. It brings the same processing power, audio quality, Neural Capture technology, and 7” touchscreen in a footprint that fits effortlessly into pedalboards, modern rigs, or on your desktop. Built for exceptional performance at its size and price, Quad Cortex mini makes it easy to dial in world-class sounds, explore a vast range of amps, effects, and Captures, and build rigs without creative limits wherever you play. Whether you’re stepping into the Quad Cortex platform for the first time or already feel at home, Quad Cortex mini shares the same platform and workflow, making great sounds fast, intuitive, and deeply rewarding from the first note. Quad Cortex mini is available now from select dealers. Find out more at

Introducing Quad Cortex mini Quad Cortex mini delivers the full Quad Cortex experience in our most compact, usable format yet, without cutting corners. It brings the same processing power, audio quality, Neural Capture technology, and 7” touchscreen in a footprint that fits effortlessly into pedalboards, modern rigs, or on your desktop. Built for exceptional performance at its size and price, Quad Cortex mini makes it easy to dial in world-class sounds, explore a vast range of amps, effects, and Captures, and build rigs without creative limits wherever you play. Whether you’re stepping into the Quad Cortex platform for the first time or already feel at home, Quad Cortex mini shares the same platform and workflow, making great sounds fast, intuitive, and deeply rewarding from the first note. Quad Cortex mini is available now from select dealers. Find out more at

Neural DSP

327,409 views • 8 months ago

Behind every game you love and character you cherish is a performer putting in immense hard work. That's why we're fighting for fair treatment and protections in the #VideoGameStrike. #LevelUpTheContract Check out SAG-AFTRA's panel at #SDCC2024 for more:

Behind every game you love and character you cherish is a performer putting in immense hard work. That's why we're fighting for fair treatment and protections in the #VideoGameStrike. #LevelUpTheContract Check out SAG-AFTRA's panel at #SDCC2024 for more:

SAG-AFTRA

142,493 views • 2 years ago

A lot of new faces lately, thank you all for following me! In case you missed it, the next game I'm releasing is a horror game where things take a turn for the worse during your night shift at the gas station. Check out the link in the replies, and all RTs are super helpful!

A lot of new faces lately, thank you all for following me! In case you missed it, the next game I'm releasing is a horror game where things take a turn for the worse during your night shift at the gas station. Check out the link in the replies, and all RTs are super helpful!

Fear the Phantom (game in bio)

10,277 views • 2 years ago

What is ISKRA 2.0? 🤔 Here it is in a nutshell as explained by our CBO Ben Colayco during the Southeast Asia Blockchain Week held last week in Thailand. 🇹🇭🏝️ Get ready and get set for even more amazing games, more rewarding experiences, and bigger rewards from #Iskra as we start this new chapter. 💯🚀 Check out Iskra at 🖱️

What is ISKRA 2.0? 🤔 Here it is in a nutshell as explained by our CBO Ben Colayco during the Southeast Asia Blockchain Week held last week in Thailand. 🇹🇭🏝️ Get ready and get set for even more amazing games, more rewarding experiences, and bigger rewards from #Iskra as we start this new chapter. 💯🚀 Check out Iskra at 🖱️

Iskra

12,392 views • 2 years ago

Daniel Etim Effiong: Being with a wife that is assertive was chaotic for me. This clip from an interview in November gives us more insight into the dynamics of their marriage. I hope they both get better at this marriage thingy.

Daniel Etim Effiong: Being with a wife that is assertive was chaotic for me. This clip from an interview in November gives us more insight into the dynamics of their marriage. I hope they both get better at this marriage thingy.

𝒥𝓊𝓁ℯ𝓏 💞

867,500 views • 1 year ago

RuneScape: Dragonwilds is OUT NOW on Steam in Early Access, check out the latest trailer for this co-op survival game. Get a look at combat, traversal, base building, and more. Presented by RuneScape: Dragonwilds

RuneScape: Dragonwilds is OUT NOW on Steam in Early Access, check out the latest trailer for this co-op survival game. Get a look at combat, traversal, base building, and more. Presented by RuneScape: Dragonwilds

IGN

227,567 views • 1 year ago