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NEURALINK: REAL-TIME BRAIN ACTIVITY, STREAMED Neuralink's implanted neural device is already delivering what scientists have chased for decades: live visibility into human brain activity within minutes of surgery. In this demo, signals flare as a participant wakes up post-procedure - the device capturing the gradual surge of neural activity... show more

Mario Nawfal

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204,494 次观看 • 1 年前 •via X (Twitter)

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NEURALINK: REWIRING THE FUTURE OF HUMAN PERCEPTION Neuralink begins by restoring sight. •⁠ ⁠It bypasses damaged eyes and speaks directly to the brain •⁠ ⁠Future applications may unlock vision beyond human capability •⁠ ⁠Interfaces designed to read and write neural signals in real time •⁠ ⁠Potential to restore mobility, memory, and sensory function Neural interfaces are transitioning from lab testing to human integration. A new era of brain-machine connection is underway. Source: Neuralink, Elon Musk

NEURALINK: REWIRING THE FUTURE OF HUMAN PERCEPTION Neuralink begins by restoring sight. •⁠ ⁠It bypasses damaged eyes and speaks directly to the brain •⁠ ⁠Future applications may unlock vision beyond human capability •⁠ ⁠Interfaces designed to read and write neural signals in real time •⁠ ⁠Potential to restore mobility, memory, and sensory function Neural interfaces are transitioning from lab testing to human integration. A new era of brain-machine connection is underway. Source: Neuralink, Elon Musk

Mario Nawfal

89,562 次观看 • 8 个月前

NEURALINK IMPLANTS HIT DOUBLE DIGITS GLOBALLY Neuralink is no longer lab gear – 12 humans are running it in real time! The Neuralink Count: • 12 human implants testing brain–computer hook-ups • 2,000 days of signals streaming. No shutdown • 15,000 hours logged, turning thought into input Neuralink is past prototypes – humans are the interface now! Source: Neuralink

NEURALINK IMPLANTS HIT DOUBLE DIGITS GLOBALLY Neuralink is no longer lab gear – 12 humans are running it in real time! The Neuralink Count: • 12 human implants testing brain–computer hook-ups • 2,000 days of signals streaming. No shutdown • 15,000 hours logged, turning thought into input Neuralink is past prototypes – humans are the interface now! Source: Neuralink

Mario Nawfal

111,552 次观看 • 1 年前

Scientists suspect that at the threshold of death, the human brain may display activity patterns similar to memory replay. One published study reported intriguing findings from EEG recordings of an 87-year-old patient who died of a heart attack. The study observed elevated gamma brain waves, which are often associated with memory, dreaming, and conscious thought. This phenomenon is sometimes referred to as a “life recall experience,” in which a person subjectively feels as if they are replaying moments from their life immediately before or after the heart stops beating. This may occur because as the brain begins to lose its oxygen supply, it can release bursts of intense neural activity in parts of the cerebral cortex, potentially triggering a surge in memory-related processing. Although more research is needed, these findings offer a new perspective on how the brain may still show organized activity even after the heart has stopped. This could provide a biological basis for various reports of near-death experiences, which often include life review or vivid flashbacks.

Scientists suspect that at the threshold of death, the human brain may display activity patterns similar to memory replay. One published study reported intriguing findings from EEG recordings of an 87-year-old patient who died of a heart attack. The study observed elevated gamma brain waves, which are often associated with memory, dreaming, and conscious thought. This phenomenon is sometimes referred to as a “life recall experience,” in which a person subjectively feels as if they are replaying moments from their life immediately before or after the heart stops beating. This may occur because as the brain begins to lose its oxygen supply, it can release bursts of intense neural activity in parts of the cerebral cortex, potentially triggering a surge in memory-related processing. Although more research is needed, these findings offer a new perspective on how the brain may still show organized activity even after the heart has stopped. This could provide a biological basis for various reports of near-death experiences, which often include life review or vivid flashbacks.

Kekius Maximus

1,079,947 次观看 • 7 个月前

For most of neuroscience history (until the late 1980s/early 1990s), neurons were treated as the brain’s only decision-makers. That idea is changing. Astrocytes, once considered passive support cells, are now recognized as global regulators of brain state. They don’t encode individual thoughts or actions. Instead, they integrate activity across huge numbers of synapses and adjust how neural networks behave over time. By releasing modulatory signals and tracking slow changes in activity, astrocytes influence: -Alertness vs. fatigue -Stress vs. calm -Motivation vs. disengagement Importantly, they can shift brain function without rewiring neurons, by tuning the environment neurons operate in. The brain isn’t just wired. It’s regulated, and astrocytes play a central role in that regulation.

For most of neuroscience history (until the late 1980s/early 1990s), neurons were treated as the brain’s only decision-makers. That idea is changing. Astrocytes, once considered passive support cells, are now recognized as global regulators of brain state. They don’t encode individual thoughts or actions. Instead, they integrate activity across huge numbers of synapses and adjust how neural networks behave over time. By releasing modulatory signals and tracking slow changes in activity, astrocytes influence: -Alertness vs. fatigue -Stress vs. calm -Motivation vs. disengagement Importantly, they can shift brain function without rewiring neurons, by tuning the environment neurons operate in. The brain isn’t just wired. It’s regulated, and astrocytes play a central role in that regulation.

William A. Wallace, Ph.D.

12,221 次观看 • 7 个月前

🚨 SCIENTISTS ARE USING AI TO MAP A HIDDEN “CLEANING SYSTEM” INSIDE THE HUMAN BRAIN AND IT COULD CHANGE HOW WE UNDERSTAND SLEEP, AGING, AND NEURODEGENERATIVE DISEASE. It’s called the glymphatic system a vast network of fluid channels that flushes toxic waste from the brain while you sleep. For years it was almost impossible to observe in detail. Now AI-powered imaging is revealing it like a living galaxy of microscopic rivers and pathways inside neural tissue. Why this matters: Your brain produces toxic proteins constantly. The glymphatic system is one of its primary waste-clearance mechanisms clearing the very proteins linked to Alzheimer’s, Parkinson’s, and other neurodegenerative diseases. But here’s the unsettling part: This cleaning system becomes dramatically less efficient with age, poor sleep, stress, and brain injury. Sleep may not just “rest” your mind it may literally wash your brain. The deeper implication is staggering: The brain isn’t just a computer. It’s a dynamic, living network that constantly rebuilds and cleanses itself in real time. The more we map it, the more it looks like an entire universe of connected energy flows inside our skulls. What if some neurological diseases begin when the brain can no longer properly “wash” itself at night? Follow for more frontier neuroscience and future technology.

🚨 SCIENTISTS ARE USING AI TO MAP A HIDDEN “CLEANING SYSTEM” INSIDE THE HUMAN BRAIN AND IT COULD CHANGE HOW WE UNDERSTAND SLEEP, AGING, AND NEURODEGENERATIVE DISEASE. It’s called the glymphatic system a vast network of fluid channels that flushes toxic waste from the brain while you sleep. For years it was almost impossible to observe in detail. Now AI-powered imaging is revealing it like a living galaxy of microscopic rivers and pathways inside neural tissue. Why this matters: Your brain produces toxic proteins constantly. The glymphatic system is one of its primary waste-clearance mechanisms clearing the very proteins linked to Alzheimer’s, Parkinson’s, and other neurodegenerative diseases. But here’s the unsettling part: This cleaning system becomes dramatically less efficient with age, poor sleep, stress, and brain injury. Sleep may not just “rest” your mind it may literally wash your brain. The deeper implication is staggering: The brain isn’t just a computer. It’s a dynamic, living network that constantly rebuilds and cleanses itself in real time. The more we map it, the more it looks like an entire universe of connected energy flows inside our skulls. What if some neurological diseases begin when the brain can no longer properly “wash” itself at night? Follow for more frontier neuroscience and future technology.

TheNewPhysics

15,641 次观看 • 3 个月前

A paralyzed man composes music using only his thoughts 69-year-old psychologist Galen Backwalter was paralyzed below the chest after a diving accident at the age of 16. In 2024, he had six Blackrock Neurotech chips implanted in his motor cortex to convert neural signals into sound. The system reads brain activity when he imagines movement and translates it into musical notes.

A paralyzed man composes music using only his thoughts 69-year-old psychologist Galen Backwalter was paralyzed below the chest after a diving accident at the age of 16. In 2024, he had six Blackrock Neurotech chips implanted in his motor cortex to convert neural signals into sound. The system reads brain activity when he imagines movement and translates it into musical notes.

NEXTA

37,020 次观看 • 5 个月前

Meta open-sourced a brain-to-text system that reaches 78% word accuracy without surgery. Brain2Qwerty v2 converts non-invasive brain recordings into text with 61% average word accuracy and 78% for its strongest participant. The system reads MEG signals from a helmet, not electrodes placed inside brain tissue. 9 volunteers typed about 22,000 sentences while researchers recorded 10 hours of neural activity each. Brain2Qwerty v1 mostly mapped brain signals to single typed characters. It tries to recover characters, words, and full sentence meaning together. The system studies those brain signals and tries to turn them into the words you wanted to type. - 61% average word accuracy across all participants - 78% word accuracy for the top participant - 50%+ of sentences decoded with no more than 1 word error Performance improves as the data pile grows Raw brain signals are messy because many mental and physical processes fire at once. Deep learning handles that mess by learning patterns directly from the original recordings. A fine-tuned LLM then uses language context to repair likely word and sentence errors. This explains why the system beats earlier non-invasive methods reporting 8% word accuracy. More than half of sentences from the strongest participant had one word error or less. Accuracy also improved as training data grew, suggesting more recordings may close more of the gap.

Meta open-sourced a brain-to-text system that reaches 78% word accuracy without surgery. Brain2Qwerty v2 converts non-invasive brain recordings into text with 61% average word accuracy and 78% for its strongest participant. The system reads MEG signals from a helmet, not electrodes placed inside brain tissue. 9 volunteers typed about 22,000 sentences while researchers recorded 10 hours of neural activity each. Brain2Qwerty v1 mostly mapped brain signals to single typed characters. It tries to recover characters, words, and full sentence meaning together. The system studies those brain signals and tries to turn them into the words you wanted to type. - 61% average word accuracy across all participants - 78% word accuracy for the top participant - 50%+ of sentences decoded with no more than 1 word error Performance improves as the data pile grows Raw brain signals are messy because many mental and physical processes fire at once. Deep learning handles that mess by learning patterns directly from the original recordings. A fine-tuned LLM then uses language context to repair likely word and sentence errors. This explains why the system beats earlier non-invasive methods reporting 8% word accuracy. More than half of sentences from the strongest participant had one word error or less. Accuracy also improved as training data grew, suggesting more recordings may close more of the gap.

Rohan Paul

17,127 次观看 • 2 个月前

OPINION: WILL NEURALINK LET HUMANS KEEP UP WITH SUPERINTELLIGENT AI? The truth is simple. In the next five to ten years we could have AI thousands of times smarter than any human. Our brains are amazing, but they are slow compared to AI. We speak about 150 words a minute and type even slower. Super intelligent AI will think and solve problems at speeds we cannot imagine. Neuralink is a solution. That amazing, tiny implant connects your brain directly to computers. You think and the machine responds instantly, no more slow keyboards or speech. More than a dozen people already have Neuralink implants. Some who were fully paralyzed are now playing video games, designing 3D models, and controlling computers just by thinking. Elon says the next steps are real telepathy and downloading knowledge straight into your brain. The plan is not to beat super intelligent AI in a race we cannot win. The plan is to team up with it. A high-speed brain link lets our human creativity, emotions, and values guide the AI while we get its incredible power. In the future, will there be a day without Neuralink, most people get left behind?

OPINION: WILL NEURALINK LET HUMANS KEEP UP WITH SUPERINTELLIGENT AI? The truth is simple. In the next five to ten years we could have AI thousands of times smarter than any human. Our brains are amazing, but they are slow compared to AI. We speak about 150 words a minute and type even slower. Super intelligent AI will think and solve problems at speeds we cannot imagine. Neuralink is a solution. That amazing, tiny implant connects your brain directly to computers. You think and the machine responds instantly, no more slow keyboards or speech. More than a dozen people already have Neuralink implants. Some who were fully paralyzed are now playing video games, designing 3D models, and controlling computers just by thinking. Elon says the next steps are real telepathy and downloading knowledge straight into your brain. The plan is not to beat super intelligent AI in a race we cannot win. The plan is to team up with it. A high-speed brain link lets our human creativity, emotions, and values guide the AI while we get its incredible power. In the future, will there be a day without Neuralink, most people get left behind?

Mario Nawfal

29,841 次观看 • 9 个月前

Imagine your mind still knows exactly where it wants to go. Paralyzed, your body just stopped taking the message. Neuralink is fixing the broken connection between the mind and the body. Clinical trial participants are now using brain implants to control powered wheelchairs through thought. The implant reads neural signals. Algorithms decode the intent. The chair moves. For people whose mind-body connection has been disrupted, that’s a very serious kind of freedom. Neuralink / Writer: Annette, Grok Imagine Designer: Janné

Imagine your mind still knows exactly where it wants to go. Paralyzed, your body just stopped taking the message. Neuralink is fixing the broken connection between the mind and the body. Clinical trial participants are now using brain implants to control powered wheelchairs through thought. The implant reads neural signals. Algorithms decode the intent. The chair moves. For people whose mind-body connection has been disrupted, that’s a very serious kind of freedom. Neuralink / Writer: Annette, Grok Imagine Designer: Janné

Mario Nawfal

67,548 次观看 • 1 个月前

WTF: Mind reading is here. Researchers invented a new #AI method to convert brain signals into video. See the results for yourself Published in Nature yesterday: What are the implications? Is this the biggest paper of 2023? #CEBRA

WTF: Mind reading is here. Researchers invented a new #AI method to convert brain signals into video. See the results for yourself Published in Nature yesterday: What are the implications? Is this the biggest paper of 2023? #CEBRA

andrew gao

679,449 次观看 • 3 年前

NEURALINK: WHERE YOUR THOUGHTS LITERALLY CONTROL THE WORLD AROUND YOU It’s not imagination. It’s movement, precision, and control, all from the mind alone. •⁠ ⁠Neuralink bypasses broken pathways, restoring motion through direct brain signals •⁠ ⁠Thought turns into action in under 100ms: faster than most natural reflexes •⁠ ⁠Robotic limbs respond instantly, moving like seamless extensions of your body •⁠ ⁠Users play games, browse, and type with pure intention, no movement required •⁠ ⁠This is more than tech; it’s the foundation of human-AI symbiosis The mind-machine merge has started, rewriting what it means to be human forever. Source: xAI, Massachusetts Institute of Technology (MIT)

NEURALINK: WHERE YOUR THOUGHTS LITERALLY CONTROL THE WORLD AROUND YOU It’s not imagination. It’s movement, precision, and control, all from the mind alone. •⁠ ⁠Neuralink bypasses broken pathways, restoring motion through direct brain signals •⁠ ⁠Thought turns into action in under 100ms: faster than most natural reflexes •⁠ ⁠Robotic limbs respond instantly, moving like seamless extensions of your body •⁠ ⁠Users play games, browse, and type with pure intention, no movement required •⁠ ⁠This is more than tech; it’s the foundation of human-AI symbiosis The mind-machine merge has started, rewriting what it means to be human forever. Source: xAI, Massachusetts Institute of Technology (MIT)

Mario Nawfal

99,457 次观看 • 8 个月前

You’re looking at neurons growing and connecting in real time 🧠. A 65-hour recording of hippocampal activity in a rat brain. The hippocampus plays a crucial role in memory and learning. In this footage, neurons extend their dendrites and axons, building and reshaping connections across days. Capturing this process live offers a rare view into how neural circuits form and reorganize. Why this matters ⬇️ 1️⃣It’s a continuous, multi-day recording of living hippocampal neurons under the microscope 2️⃣You can clearly see dendritic branching and network formation 3️⃣It reveals the dynamic processes that drive brain development and plasticity Observing growth at this resolution helps researchers understand how neurons connect—and how disruptions in these processes might contribute to neurological or psychiatric conditions. Credit to Louis Romet and Dr. Christophe Leterrier for the video

You’re looking at neurons growing and connecting in real time 🧠. A 65-hour recording of hippocampal activity in a rat brain. The hippocampus plays a crucial role in memory and learning. In this footage, neurons extend their dendrites and axons, building and reshaping connections across days. Capturing this process live offers a rare view into how neural circuits form and reorganize. Why this matters ⬇️ 1️⃣It’s a continuous, multi-day recording of living hippocampal neurons under the microscope 2️⃣You can clearly see dendritic branching and network formation 3️⃣It reveals the dynamic processes that drive brain development and plasticity Observing growth at this resolution helps researchers understand how neurons connect—and how disruptions in these processes might contribute to neurological or psychiatric conditions. Credit to Louis Romet and Dr. Christophe Leterrier for the video

William A. Wallace, Ph.D.

67,637 次观看 • 10 个月前

No surgery. No wires. No brain implant. A retainer that controls your iPhone with your tongue. This is MIT's 0.7mm answer to Neuralink. The startup Augmental built a device called the MouthPad. Founder Tomás Vega designed it as a dental-grade smart retainer. It sits on the roof of your palate. A capacitive trackpad reads tongue movement as input. Users swipe, tap, and type completely hands-free. The device runs about 9 hours per charge. Augmental reports 100+ users already deployed in the field. Neuralink requires skull surgery to read brain signals. This approach grants similar independence with zero medical risk. It serves people with spinal cord injuries and paralysis. Sometimes the smartest answer skips the operating room entirely. QUESTIONS: Where else do we reach for surgery when simpler tools exist? What makes assistive tech go from clever demo to daily lifeline? Leave your thoughts and comments below 👇 --- 🎁 Join 10,000+ others who learned gamification for FREE: ♻️ REPOST to inspire your community And FOLLOW Yu-kai Chou for more content like this

No surgery. No wires. No brain implant. A retainer that controls your iPhone with your tongue. This is MIT's 0.7mm answer to Neuralink. The startup Augmental built a device called the MouthPad. Founder Tomás Vega designed it as a dental-grade smart retainer. It sits on the roof of your palate. A capacitive trackpad reads tongue movement as input. Users swipe, tap, and type completely hands-free. The device runs about 9 hours per charge. Augmental reports 100+ users already deployed in the field. Neuralink requires skull surgery to read brain signals. This approach grants similar independence with zero medical risk. It serves people with spinal cord injuries and paralysis. Sometimes the smartest answer skips the operating room entirely. QUESTIONS: Where else do we reach for surgery when simpler tools exist? What makes assistive tech go from clever demo to daily lifeline? Leave your thoughts and comments below 👇 --- 🎁 Join 10,000+ others who learned gamification for FREE: ♻️ REPOST to inspire your community And FOLLOW Yu-kai Chou for more content like this

Yu-kai Chou

17,185 次观看 • 3 个月前

NEURALINK: CJ suffered a spinal cord injury and is ventilator-dependent. A few months ago, he was selected for the Neuralink PRIME Study at The Miami Project to Cure Paralysis. He recently underwent N1 implant surgery. at the University of Miami's Miller School of Medicine, with Neuralink co-investigator Dr. Michael E. Ivan, UoM Associate Professor of at the Miller School of Medicine Neurological Surgery and The Miami Project to Cure Paralysis. Per CJ, "In addition to being a stellar neurosurgeon, Dr. Ivan is really quite hilarious. Totally put me at ease even knowing that I was about to get a hole put in my head and wake up a cyborg!" Right after surgery in the hospital, Neuralink Software Engineer Natalie Cygan stopped by his room, set up the Neuralink laptop, showed the brain waves, and gave his wife her personal cell number for future questions. Per CJ, "Shortly after my surgery, a Neuralink engineer stopped by my hospital room to show my wife my brain waves. For the purpose of future arguments, Sweetie, this proves once and for all that I do have a brain..." A day or two later at home, Neuralink's Sehej Bindra visited to assist with the N1 implant setup and training. CJ reached 6.23 BPS on WebGrid according to Sehej and they celebrated the success. Sehej is the the brainchild behind SimpleCell, a platform to integrate and streamline the bioinformatics research. Per CJ, "Sehej is awesome. Came to my house three days straight to train me on my N1 and still meets with me virtually." At his 1-month post-op visit, Dr. Ivan confirmed the surgery healed and the N1 implant was in the right place. The CT scan above shows how the implant looks in his skull. CJ called the clinical trial very encouraging because participants recovered tremendous respiratory function and the work of weaning from the ventilator helps keep motor neurons alive. CJ (Neuralink P24), Michael Ivan, MD, MBS, FAANS

NEURALINK: CJ suffered a spinal cord injury and is ventilator-dependent. A few months ago, he was selected for the Neuralink PRIME Study at The Miami Project to Cure Paralysis. He recently underwent N1 implant surgery. at the University of Miami's Miller School of Medicine, with Neuralink co-investigator Dr. Michael E. Ivan, UoM Associate Professor of at the Miller School of Medicine Neurological Surgery and The Miami Project to Cure Paralysis. Per CJ, "In addition to being a stellar neurosurgeon, Dr. Ivan is really quite hilarious. Totally put me at ease even knowing that I was about to get a hole put in my head and wake up a cyborg!" Right after surgery in the hospital, Neuralink Software Engineer Natalie Cygan stopped by his room, set up the Neuralink laptop, showed the brain waves, and gave his wife her personal cell number for future questions. Per CJ, "Shortly after my surgery, a Neuralink engineer stopped by my hospital room to show my wife my brain waves. For the purpose of future arguments, Sweetie, this proves once and for all that I do have a brain..." A day or two later at home, Neuralink's Sehej Bindra visited to assist with the N1 implant setup and training. CJ reached 6.23 BPS on WebGrid according to Sehej and they celebrated the success. Sehej is the the brainchild behind SimpleCell, a platform to integrate and streamline the bioinformatics research. Per CJ, "Sehej is awesome. Came to my house three days straight to train me on my N1 and still meets with me virtually." At his 1-month post-op visit, Dr. Ivan confirmed the surgery healed and the N1 implant was in the right place. The CT scan above shows how the implant looks in his skull. CJ called the clinical trial very encouraging because participants recovered tremendous respiratory function and the work of weaning from the ventilator helps keep motor neurons alive. CJ (Neuralink P24), Michael Ivan, MD, MBS, FAANS

S.E. Robinson, Jr.

13,791 次观看 • 5 个月前

THIS IS WHAT YOUR SECOND BRAIN SHOULD LOOK LIKE most people dump notes into obsidian and call it a second brain it’s not a second brain it’s a second drawer karpathy just dropped the pattern that changes this and it’s called the llm wiki every time you add a source ai reads it, extracts key claims, updates every connected note and flags contradictions your obsidian stops being an archive and starts being alive save this and show it to someone still using notion as a second brain full breakdown in the article ↓

THIS IS WHAT YOUR SECOND BRAIN SHOULD LOOK LIKE most people dump notes into obsidian and call it a second brain it’s not a second brain it’s a second drawer karpathy just dropped the pattern that changes this and it’s called the llm wiki every time you add a source ai reads it, extracts key claims, updates every connected note and flags contradictions your obsidian stops being an archive and starts being alive save this and show it to someone still using notion as a second brain full breakdown in the article ↓

leopardracer

123,618 次观看 • 2 个月前

Every thought you repeat is training your brain. Including the ones destroying you. Every repeated thought is a tiny vote for what your brain should make easier next time. That’s the strange thing about your brain. It doesn’t only learn the things you sit down and decide to learn. It learns what you rehearse. The worry you revisit. The story you keep telling yourself. The reaction you repeat. But also the skill you practice, the courage you keep choosing, and the new response that feels awkward at first. None of those repetitions feels life-changing in the moment. But your brain is paying attention. (This is What Happens in Your Brain When You Learn Something New)

Every thought you repeat is training your brain. Including the ones destroying you. Every repeated thought is a tiny vote for what your brain should make easier next time. That’s the strange thing about your brain. It doesn’t only learn the things you sit down and decide to learn. It learns what you rehearse. The worry you revisit. The story you keep telling yourself. The reaction you repeat. But also the skill you practice, the courage you keep choosing, and the new response that feels awkward at first. None of those repetitions feels life-changing in the moment. But your brain is paying attention. (This is What Happens in Your Brain When You Learn Something New)

Mind Essentials

49,904 次观看 • 5 天前

💜 One Last Update! 💜 Last week when we were in Minnesota for Clark’s 6-month follow-up for his clinical trial, of all the tests they ran, the one we were both most anxious and most eager to see results from was his brain MRI. For children with untreated Sanfilippo Type A, it’s typical to see 2–5% loss of brain volume each year, along with enlargement of the ventricles (the fluid-filled spaces in the brain). This is one of the most heartbreaking parts of the disease — watching the brain slowly lose tissue and function over time. We were so nervous that Clark’s MRI might show some loss compared to his baseline scan 6 months ago. But the results came back and… ✨ ZERO change. ✨ His brain volume and ventricle size were completely stable — no loss at all. This is such an incredible sign that the treatment may be doing exactly what it’s meant to: clearing the toxic waste from his brain cells and protecting his brain from further damage. If feel that it is SO important for us to share these results as they come because people need to be FULLY aware that these treatments that are out there WORK. These children with Sanfilippo do not need to regress and they DEFINITELY do not have to have their lives cut short. We just need the FDA to say yes. We are so close to a reality where Sanfilippo syndrome is as manageable as a disease like diabetes. P.S. Enjoy this video of our little sunshine having the best time singing!

💜 One Last Update! 💜 Last week when we were in Minnesota for Clark’s 6-month follow-up for his clinical trial, of all the tests they ran, the one we were both most anxious and most eager to see results from was his brain MRI. For children with untreated Sanfilippo Type A, it’s typical to see 2–5% loss of brain volume each year, along with enlargement of the ventricles (the fluid-filled spaces in the brain). This is one of the most heartbreaking parts of the disease — watching the brain slowly lose tissue and function over time. We were so nervous that Clark’s MRI might show some loss compared to his baseline scan 6 months ago. But the results came back and… ✨ ZERO change. ✨ His brain volume and ventricle size were completely stable — no loss at all. This is such an incredible sign that the treatment may be doing exactly what it’s meant to: clearing the toxic waste from his brain cells and protecting his brain from further damage. If feel that it is SO important for us to share these results as they come because people need to be FULLY aware that these treatments that are out there WORK. These children with Sanfilippo do not need to regress and they DEFINITELY do not have to have their lives cut short. We just need the FDA to say yes. We are so close to a reality where Sanfilippo syndrome is as manageable as a disease like diabetes. P.S. Enjoy this video of our little sunshine having the best time singing!

Brutus Stark

48,090 次观看 • 10 个月前

AN ANTHROPIC LEAD ENGINEER ACCIDENTALLY LEAKED HIS PERSONAL OBSIDIAN. INSIDE - NOT CODE OR PROMPTS, BUT A DIAGRAM OF HIS OWN BRAIN, ORGANIZED AS A NEURAL NETWORK 8,893 nodes. 4,729 connections. A $10/month app opens Obsidian. 21 inputs, ReLU on every layer. The first hidden layer has 26 neurons, followed by 33, then 24, and so on all the way to the output. Thousands of connections flash in real time this isn’t a conceptual diagram from a blog, but a living brain that powers decision-making within the company. 9,000 documents, each with its own semantic space, all interconnected it earns about $2m a year for sorting Markdown files into the right folders. The company that builds the world’s best AI maintains its internal knowledge base in the same app that a freshman uses for class notes three years of discipline and a single open Obsidian tab you’re reading this on a device where, tonight, you can open that same Obsidian and start building your own vault

AN ANTHROPIC LEAD ENGINEER ACCIDENTALLY LEAKED HIS PERSONAL OBSIDIAN. INSIDE - NOT CODE OR PROMPTS, BUT A DIAGRAM OF HIS OWN BRAIN, ORGANIZED AS A NEURAL NETWORK 8,893 nodes. 4,729 connections. A $10/month app opens Obsidian. 21 inputs, ReLU on every layer. The first hidden layer has 26 neurons, followed by 33, then 24, and so on all the way to the output. Thousands of connections flash in real time this isn’t a conceptual diagram from a blog, but a living brain that powers decision-making within the company. 9,000 documents, each with its own semantic space, all interconnected it earns about $2m a year for sorting Markdown files into the right folders. The company that builds the world’s best AI maintains its internal knowledge base in the same app that a freshman uses for class notes three years of discipline and a single open Obsidian tab you’re reading this on a device where, tonight, you can open that same Obsidian and start building your own vault

chewa

359,674 次观看 • 2 个月前

Imagine spending $4,000,000,000 on spatial AI just to get publicly humiliated by a guy in sweatpants Unitree’s $16,000 G1 humanoid didn't just fall, it experienced a total algorithmic panic attack the second a street ball player dropped a simple crossover. Here is what actually happened on that court: Neural Network Brain Freeze: The AI was trained on linear lab movements, so when the player faked left, the neural net’s trajectory prediction completely imploded in real time. Hardware Rejection: Unitree built the G1 for cheap mass production, but its budget joint actuators flat-out refused to handle the high-G rotational force required to turn. The Latency Trap: Human reflexes operate at sub-millisecond speeds, while the bot’s onboard vision processor was still trying to locate the ball as its head hit the floor.

Imagine spending $4,000,000,000 on spatial AI just to get publicly humiliated by a guy in sweatpants Unitree’s $16,000 G1 humanoid didn't just fall, it experienced a total algorithmic panic attack the second a street ball player dropped a simple crossover. Here is what actually happened on that court: Neural Network Brain Freeze: The AI was trained on linear lab movements, so when the player faked left, the neural net’s trajectory prediction completely imploded in real time. Hardware Rejection: Unitree built the G1 for cheap mass production, but its budget joint actuators flat-out refused to handle the high-G rotational force required to turn. The Latency Trap: Human reflexes operate at sub-millisecond speeds, while the bot’s onboard vision processor was still trying to locate the ball as its head hit the floor.

Piggle

30,497 次观看 • 16 天前