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New feature unlocked for Prism. Spot, Perps, Lending (and more...) will be available directly on Prism. One place. One flow. Only MegaETH speed. Powered by not hersch.

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Prism

13,182 subscribers

21,423 Aufrufe • vor 7 Monaten •via X (Twitter)

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Prism is live on Arbitrum. Arbitrum is building the finance-native platform for the programmable economy. Prism is where the pieces of Arbitrum’s financial stack start coming together. Starting with: → GMX 🫐 perps → USD.AI staking → Morpho 🦋 vaults Perps, staking, lending yields, and Arbitrum DeFi through one non-custodial app. The bigger Arbitrum experience starts here.

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E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves. We discovered a new cell barcoding approach exceeding comparable methods by more than 750x. This is the heart of PRISM. We integrated this capability with microscopy and AI image analysis to automatically trace neurons at high resolution and annotate them with molecular features. This is a key advance towards economically viable brain mapping - 95% of costs stem from neuron tracing. It is also an important step towards democratizing neuron tracing for everyday neuroscience. Solving these problems is critical for curing brain disorders, building safer and human-like AI, and even simulating brain function. In our first pilot study, we acquired a unique dataset in mouse hippocampus. Barcodes improved the accuracy of tracing genetically labelled neurons by 8x – with a clear path to 100x or more. They also permit tracing across spatial gaps – essential for mitigating tissue section loss in whole-brain scaling. Using molecular annotation, we uncover an intriguing feature of synaptic organization, demonstrating how PRISM can be used for systematic discovery 🧵

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