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Reductionism has been a powerful force for understanding fundamental aspects of complex systems, but its very success has blinded most biologists to its crippling inability to make sense of complex emergent dynamic systems. We have the tools now to noninvasively observe and perturb living cells in their stunning holistic...

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Eric Betzig

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51,857 görüntüleme • 2 ay önce •via X (Twitter)

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Cancer - Chemotherapy wipes out the cells that "protect your body from cancer" For decades, the fundamental protocol for fighting cancer has been chemotherapy and radiation. But what if this approach inadvertently disarms the body's most powerful weapon against the very disease it seeks to destroy? Dr. Patrick Soon-Shiong explains the profound and simple truth: When a patient undergoes chemotherapy, it systematically wipes out critical components of the immune system. 1. It wipes out red blood cells, causing anemia. We have a drug for that: Epogen. 2. It wipes out neutrophils, which prevent infection. We have a drug for that: Neupogen. 3. But most critically, it decimates the lymphocytes—the NK and T cells. Here lies the devastating irony: The NK and T cells are the only cells in the human body that can recognize and kill cancer. So, within days, the standard of care eliminates the patient's primary defense system. For 35 years, we have treated the side effects of anemia and infection, all while having no therapy to restore the very cells that matter most. Dr. Soon-Shiong’s two-decade fight has been to illuminate this paradigm. We have been unintentionally protecting the patient from the consequences of our own treatments while undermining their innate ability to survive. This principle extends beyond oncology. In Long COVID, a similar pattern emerges—a viral infection that cleverly disables the T and NK cells. The lesson is clear: The future of medicine lies not in breaking the body down, but in strategically rebuilding and empowering its innate intelligence. It’s a call to move beyond managing collateral damage and to start fortifying the core of our biological defenses.
1:47

Cancer - Chemotherapy wipes out the cells that "protect your body from cancer" For decades, the fundamental protocol for fighting cancer has been chemotherapy and radiation. But what if this approach inadvertently disarms the body's most powerful weapon against the very disease it seeks to destroy? Dr. Patrick Soon-Shiong explains the profound and simple truth: When a patient undergoes chemotherapy, it systematically wipes out critical components of the immune system. 1. It wipes out red blood cells, causing anemia. We have a drug for that: Epogen. 2. It wipes out neutrophils, which prevent infection. We have a drug for that: Neupogen. 3. But most critically, it decimates the lymphocytes—the NK and T cells. Here lies the devastating irony: The NK and T cells are the only cells in the human body that can recognize and kill cancer. So, within days, the standard of care eliminates the patient's primary defense system. For 35 years, we have treated the side effects of anemia and infection, all while having no therapy to restore the very cells that matter most. Dr. Soon-Shiong’s two-decade fight has been to illuminate this paradigm. We have been unintentionally protecting the patient from the consequences of our own treatments while undermining their innate ability to survive. This principle extends beyond oncology. In Long COVID, a similar pattern emerges—a viral infection that cleverly disables the T and NK cells. The lesson is clear: The future of medicine lies not in breaking the body down, but in strategically rebuilding and empowering its innate intelligence. It’s a call to move beyond managing collateral damage and to start fortifying the core of our biological defenses.

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The WEF's Elizabeth Thurbon argues that "disruptions" like Covid, climate change and the energy crisis demand "a fundamental rethinking of the role of the government". "In East Asia, the understanding of the purpose of the government has always been much more expansive. But in the West, we have had a very, very narrow view of what it's appropriate for the government to do." "So meeting this challenge... now requires a fundamental rethinking of the role of the government."

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Today, we’re introducing Spawnlabs We built it to push the limits of what software can be spawned, from simple tools to complex systems Software has always been a way to extend what we can do and create. and now we're building spawnlabs to automate the ability to spawn software that solves harder problems and builds deeper systems. live now

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South Africa has allowed “a certain class of people” which is approximately 7% of its population to own 70% of their land originally belonging to Africans and have been living peacefully. The former President of SA stated this aswell, if their government decides to redistribute the Land appropriately, it has every right to do so, this man, living comfortably in SA, explains this in depth in the video 👇🏾

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Today is an important day in the modern history of our nation. Thousands of students across India have been protesting for their rights, putting the future of India and its youth ahead of themselves. Every attempt by the Modi government to use force against them and suppress their voices has failed. Today, their will has prevailed. The government has been forced to bend to their demand for the Education Minister's resignation. Today is also a day to renew our faith in the vibrancy of our democracy and the strength of our people. We feel proud that we have a younger generation willing to serve, willing to build the future, and willing to put themselves forward at all costs. : Congress General Secretary & Wayanad MP Smt. Priyanka Gandhi Vadra ji at the Felicitation of the Kalladi Rescue and Relief Teams. 📍 Wayanad, Kerala

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Texas has voted to include the Bible in its K–12 curriculum and the backlash has been immediate. The Bible isn't just about religion, but about understanding the very foundations of Western civilization. Subscribe via the link in my bio!
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Texas has voted to include the Bible in its K–12 curriculum and the backlash has been immediate. The Bible isn't just about religion, but about understanding the very foundations of Western civilization. Subscribe via the link in my bio!

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Today, we are here to receive monoclonal antibodies, cutting edge therapeutics, to work against Marburg virus. Again, United States is working to provide whatever it is that we have to the people of Ethiopia and its officials in this big fight. The development of this tool has been supported by the Department of Health and Human Services of the United States government. This cutting-edge treatment represents perhaps one of the best avenues for treatment for those who suffer this terrible disease. This tool has been used before and has been deployed previously, most recently in Rwanda, which we believe perhaps has helped to address some of the worst impacts of this disease. - Ambassador Massinga

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The theory of higher order topological dynamics, which combines multilevel interactions between discrete topology and nonlinear dynamics, has the potential to enhance our understanding of complex systems such as the functions of the nervous system, the development of next-generation machine learning and the creation of advanced nodal processing algorithms. An important and unexpected collective behavior of signal processing in multilevel nodal networks has been observed to lead to a synchronization and diffusion of the irrotational and the solenoidal components of the systems revealing a deep relation of these mechanisms with the complexity of discrete topology. The perspective of the preliminary study linked here offers insights into how topology morphs dynamics, how dynamics stem from topology and how topology evolves dynamically. 🔗
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The theory of higher order topological dynamics, which combines multilevel interactions between discrete topology and nonlinear dynamics, has the potential to enhance our understanding of complex systems such as the functions of the nervous system, the development of next-generation machine learning and the creation of advanced nodal processing algorithms. An important and unexpected collective behavior of signal processing in multilevel nodal networks has been observed to lead to a synchronization and diffusion of the irrotational and the solenoidal components of the systems revealing a deep relation of these mechanisms with the complexity of discrete topology. The perspective of the preliminary study linked here offers insights into how topology morphs dynamics, how dynamics stem from topology and how topology evolves dynamically. 🔗

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So here we are in 2026 and I was so excited to hear Jim's comment just before I gave my talk, "...the field has changed a bit and it was all about taking the brakes off T cells now its understanding how T cells are modulated by all all the other different components of the immune system so its a lot more complex..." That was exactly our focus and trials over the last decade to identify the killers and the suppressors in the tumor microenvironment and orchestrate our treatment based on the dynamics of "quantum" oncotherapeutics - how NK cells and T cells modulate each other.
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So here we are in 2026 and I was so excited to hear Jim's comment just before I gave my talk, "...the field has changed a bit and it was all about taking the brakes off T cells now its understanding how T cells are modulated by all all the other different components of the immune system so its a lot more complex..." That was exactly our focus and trials over the last decade to identify the killers and the suppressors in the tumor microenvironment and orchestrate our treatment based on the dynamics of "quantum" oncotherapeutics - how NK cells and T cells modulate each other.

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