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Statins Slash GLP-1: (~10-minute Data Digest for X) Human trial data published in a major journal show that statins cause insulin resistance and deplete GLP-1 levels in humans. This should have been breaking news... But no one talked about it. Why don’t doctors know? Why aren’t patients being informed... show more

Nick Norwitz MD PhD

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168,567 views • 10 months ago •via X (Twitter)

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Ozempic has recently become a household name, but GLP-1-like drugs have actually been around for a long time. So what do we really know about the benefits and the risks – short-term and long-term? Join me this Sunday to watch our year-long investigation, to learn about these medications and why obesity is being called a disease of the brain.

Ozempic has recently become a household name, but GLP-1-like drugs have actually been around for a long time. So what do we really know about the benefits and the risks – short-term and long-term? Join me this Sunday to watch our year-long investigation, to learn about these medications and why obesity is being called a disease of the brain.

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The Statin Data Peter Attia Deleted I was surprised to find in a commentary on a human study showing Statins Slash GLP-1 levels Petter omitted the key graph When you omit the most important graph, that's not nuance. It's curation. 👉Full video:

The Statin Data Peter Attia Deleted I was surprised to find in a commentary on a human study showing Statins Slash GLP-1 levels Petter omitted the key graph When you omit the most important graph, that's not nuance. It's curation. 👉Full video:

Nick Norwitz MD PhD

71,579 views • 4 months ago

This administration has slashed billions of dollars in foreign aid — and has little data or information to share about why programs have been cut and the impact it has on communities abroad and at home. I’m demanding answers.

This administration has slashed billions of dollars in foreign aid — and has little data or information to share about why programs have been cut and the impact it has on communities abroad and at home. I’m demanding answers.

Rep. Pramila Jayapal

227,018 views • 7 months ago

Think your blood glucose tells the whole story? Think again. Dr. Ben Bikman (Benjamin Bikman) joins me to discuss insulin resistance, including why it often remains hidden until late stages and simple ways to detect it early. We explore insulin’s lesser-known roles in fat storage, appetite regulation, inflammation, and chronic disease. You’ll also learn how macronutrients, meal timing, and frequency uniquely influence your insulin sensitivity, and the critical differences between visceral and subcutaneous fat. Finally, we dive into how stress, sleep deprivation, nicotine, and environmental toxins shape your metabolism and unpack the realities of popular GLP-1 receptor agonist medications (like Ozempic), including their benefits, risks, and the intriguing potential of microdosing. We also provide practical, actionable strategies, dietary adjustments, exercise protocols, and targeted supplements that you can implement today to significantly boost insulin sensitivity and support long-term metabolic health. If you want to understand insulin resistance and take immediate steps to improve your metabolic health - this conversation is a must-watch. Watch the full episode on X and YouTube or listen on Spotify and Apple Podcasts now. Links in the comments. Timestamps: 0:00 - Introduction 1:33 - Can you be insulin resistant with normal glucose levels? 5:13 - Can glucose monitors detect hidden insulin resistance? 6:43 - What your skin reveals about insulin resistance 8:07 - Why is insulin resistance behind so many chronic diseases? 12:28 - Does obesity cause insulin resistance—or vice versa? 19:20 - Insulin’s surprising roles beyond blood sugar control 20:18 - What’s driving weight gain—insulin or calories? 27:12 - Do saturated fats cause insulin resistance? 33:44 - Why refined carbs amplify risks from saturated fat 36:46 - Fructose vs. refined sugar—which spikes insulin more? 37:43 - High-carb vs. keto—which diet controls hunger better? 42:09 - Why low-carb diets might provide a metabolic advantage 44:18 - Does exercise give you metabolic ‘wiggle room’? 48:42 - Why strength training beats cardio for insulin sensitivity 53:54 - Does meal frequency drive insulin resistance? 57:14 - Is nighttime snacking giving you insomnia? 59:06 - Can a sugary breakfast lead to overeating later? 1:04:01 - Does late-night eating disrupt sleep more than blue light? 1:05:41 - Can one bad night’s sleep trigger insulin resistance? 1:09:06 - Can air pollution cause weight gain? 1:12:58 - Vaping vs. smoking—which is worse for metabolic health? 1:14:20 - Can statins and antidepressants trigger weight gain? 1:17:04 - How to reverse insulin resistance in 90 days 1:27:35 - Ketone supplements—are the metabolic benefits real? 1:33:16 - Why some ethnicities get diabetes without obesity 1:41:11 - How oversized fat cells trigger metabolic chaos 1:46:10 - Do seed oils silently promote insulin resistance? 1:49:27 - Seed oils—always harmful or only when heated? 2:01:03 - Do fat cells shrink or disappear with weight loss? 2:03:48 - Are shrunken fat cells still insulin resistant? 2:06:23 - Injecting insulin for muscle—are the risks worth it? 2:09:27 - Are drugs like Ozempic a shortcut or solution for obesity? 2:15:55 - Are current GLP-1 agonist doses too high? 2:16:44 - Microdosing GLP-1 drugs—a solution for carb cravings? 2:22:43 - Do these medications cause muscle loss? 2:25:12 - Do GLP-1 agonist benefits extend beyond weight loss? 2:27:23 - Could these treatments actually promote longevity? 2:32:55 - The dark side of GLP-1 drugs—can they trigger depression? 2:36:14 - Insulin vs. glucose—what really drives accelerated aging? 2:41:16 - How high glucose levels damage cells 2:43:23 - How insulin shuts down your body’s stress defenses 2:47:57 - Which biomarkers best predict biological aging? 2:54:01 - Does eating dinner early improve insulin sensitivity?

Think your blood glucose tells the whole story? Think again. Dr. Ben Bikman (Benjamin Bikman) joins me to discuss insulin resistance, including why it often remains hidden until late stages and simple ways to detect it early. We explore insulin’s lesser-known roles in fat storage, appetite regulation, inflammation, and chronic disease. You’ll also learn how macronutrients, meal timing, and frequency uniquely influence your insulin sensitivity, and the critical differences between visceral and subcutaneous fat. Finally, we dive into how stress, sleep deprivation, nicotine, and environmental toxins shape your metabolism and unpack the realities of popular GLP-1 receptor agonist medications (like Ozempic), including their benefits, risks, and the intriguing potential of microdosing. We also provide practical, actionable strategies, dietary adjustments, exercise protocols, and targeted supplements that you can implement today to significantly boost insulin sensitivity and support long-term metabolic health. If you want to understand insulin resistance and take immediate steps to improve your metabolic health - this conversation is a must-watch. Watch the full episode on X and YouTube or listen on Spotify and Apple Podcasts now. Links in the comments. Timestamps: 0:00 - Introduction 1:33 - Can you be insulin resistant with normal glucose levels? 5:13 - Can glucose monitors detect hidden insulin resistance? 6:43 - What your skin reveals about insulin resistance 8:07 - Why is insulin resistance behind so many chronic diseases? 12:28 - Does obesity cause insulin resistance—or vice versa? 19:20 - Insulin’s surprising roles beyond blood sugar control 20:18 - What’s driving weight gain—insulin or calories? 27:12 - Do saturated fats cause insulin resistance? 33:44 - Why refined carbs amplify risks from saturated fat 36:46 - Fructose vs. refined sugar—which spikes insulin more? 37:43 - High-carb vs. keto—which diet controls hunger better? 42:09 - Why low-carb diets might provide a metabolic advantage 44:18 - Does exercise give you metabolic ‘wiggle room’? 48:42 - Why strength training beats cardio for insulin sensitivity 53:54 - Does meal frequency drive insulin resistance? 57:14 - Is nighttime snacking giving you insomnia? 59:06 - Can a sugary breakfast lead to overeating later? 1:04:01 - Does late-night eating disrupt sleep more than blue light? 1:05:41 - Can one bad night’s sleep trigger insulin resistance? 1:09:06 - Can air pollution cause weight gain? 1:12:58 - Vaping vs. smoking—which is worse for metabolic health? 1:14:20 - Can statins and antidepressants trigger weight gain? 1:17:04 - How to reverse insulin resistance in 90 days 1:27:35 - Ketone supplements—are the metabolic benefits real? 1:33:16 - Why some ethnicities get diabetes without obesity 1:41:11 - How oversized fat cells trigger metabolic chaos 1:46:10 - Do seed oils silently promote insulin resistance? 1:49:27 - Seed oils—always harmful or only when heated? 2:01:03 - Do fat cells shrink or disappear with weight loss? 2:03:48 - Are shrunken fat cells still insulin resistant? 2:06:23 - Injecting insulin for muscle—are the risks worth it? 2:09:27 - Are drugs like Ozempic a shortcut or solution for obesity? 2:15:55 - Are current GLP-1 agonist doses too high? 2:16:44 - Microdosing GLP-1 drugs—a solution for carb cravings? 2:22:43 - Do these medications cause muscle loss? 2:25:12 - Do GLP-1 agonist benefits extend beyond weight loss? 2:27:23 - Could these treatments actually promote longevity? 2:32:55 - The dark side of GLP-1 drugs—can they trigger depression? 2:36:14 - Insulin vs. glucose—what really drives accelerated aging? 2:41:16 - How high glucose levels damage cells 2:43:23 - How insulin shuts down your body’s stress defenses 2:47:57 - Which biomarkers best predict biological aging? 2:54:01 - Does eating dinner early improve insulin sensitivity?

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New episode of HARD DRUGS! Should everyone be taking statins? Statins have revolutionised heart disease and they're one of many reasons for the long-term decline in cardiovascular mortality. Clinical trials suggest that the more you reduce LDL cholesterol levels, the more you reduce the risks of heart attacks and strokes, with no signal of harms even at the lowest levels. So scientists recommend the earlier they're taken the better, and the lower LDL levels you reach the better. Statins do have some rare side effects – such as muscle weakness and muscle loss in rare cases – but meta-analyses of RCTs find that most other side effects listed on statins' labels do not actually have higher risks than placebo. In this episode, Jacob Trefethen and I chat about all this and much more! - Why it took almost a century for scientists to come to consensus on "the lipid hypothesis": that higher levels of plasma LDL cholesterol causes higher risks of heart disease and that reducing it saves lives. - Drugs that effectively reduce cholesterol levels beyond the effect of statins, such as PCSK9 inhibitors, most of which are monoclonal antibodies, as well as newer siRNA drugs and the macrocyclic peptide enlicitide, which recently completed phase 3 trials, and Lp(a) drugs. - What the future holds for cholesterol drugs Timestamps: 0:00:00 Introduction 13:35 The decline in heart disease mortality 31:02 Surprising cholesterol trivia 55:40 The lipid hypothesis: 7 lines of evidence for the harms of LDL cholesterol 1:22:15 How cholesterol works 1:30:40 The discovery of statins 1:48:44 Should everyone be on statins? 1:57:10 PCSK9 drugs and beyond 2:22:56 Summary: how we got here and the future of cholesterol drugs Watch, listen, or read wherever you get your podcasts. Spotify: Apple: YouTube: Transcript:

New episode of HARD DRUGS! Should everyone be taking statins? Statins have revolutionised heart disease and they're one of many reasons for the long-term decline in cardiovascular mortality. Clinical trials suggest that the more you reduce LDL cholesterol levels, the more you reduce the risks of heart attacks and strokes, with no signal of harms even at the lowest levels. So scientists recommend the earlier they're taken the better, and the lower LDL levels you reach the better. Statins do have some rare side effects – such as muscle weakness and muscle loss in rare cases – but meta-analyses of RCTs find that most other side effects listed on statins' labels do not actually have higher risks than placebo. In this episode, Jacob Trefethen and I chat about all this and much more! - Why it took almost a century for scientists to come to consensus on "the lipid hypothesis": that higher levels of plasma LDL cholesterol causes higher risks of heart disease and that reducing it saves lives. - Drugs that effectively reduce cholesterol levels beyond the effect of statins, such as PCSK9 inhibitors, most of which are monoclonal antibodies, as well as newer siRNA drugs and the macrocyclic peptide enlicitide, which recently completed phase 3 trials, and Lp(a) drugs. - What the future holds for cholesterol drugs Timestamps: 0:00:00 Introduction 13:35 The decline in heart disease mortality 31:02 Surprising cholesterol trivia 55:40 The lipid hypothesis: 7 lines of evidence for the harms of LDL cholesterol 1:22:15 How cholesterol works 1:30:40 The discovery of statins 1:48:44 Should everyone be on statins? 1:57:10 PCSK9 drugs and beyond 2:22:56 Summary: how we got here and the future of cholesterol drugs Watch, listen, or read wherever you get your podcasts. Spotify: Apple: YouTube: Transcript:

Saloni

734,864 views • 4 months ago

This shutdown fight is about one thing and one thing only: the cost of health care. It’s always been about making sure my constituents’ health care costs don’t go through the roof. That’s why I’m in this fight.

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The fact that the universe doesn’t care about you doesn’t mean that other humans don’t care about you, or that we don’t have to care about other humans. That is, there is a purpose, there is a meaning: that is, to make people as well off as possible, to increase flourishing, to increase knowledge and life and health and freedom and safety. These are really, really meaningful. At least, I think they are. I don’t see anything wrong with them. I don’t think that that should leave you empty. And the fact that we live in a cold universe—that is, the laws of physics, the laws of biology, the behavior of viruses and bacteria and parasites and fungi—they don’t care about you. I’m sorry, they don’t care about you. And the sooner you realize that, the more you’ll be able to attend to the things that really do matter. Human Progress

The fact that the universe doesn’t care about you doesn’t mean that other humans don’t care about you, or that we don’t have to care about other humans. That is, there is a purpose, there is a meaning: that is, to make people as well off as possible, to increase flourishing, to increase knowledge and life and health and freedom and safety. These are really, really meaningful. At least, I think they are. I don’t see anything wrong with them. I don’t think that that should leave you empty. And the fact that we live in a cold universe—that is, the laws of physics, the laws of biology, the behavior of viruses and bacteria and parasites and fungi—they don’t care about you. I’m sorry, they don’t care about you. And the sooner you realize that, the more you’ll be able to attend to the things that really do matter. Human Progress

Steven Pinker

70,883 views • 3 months ago

🔥🚨BREAKING: I got pressed by Flakko for supporting ICE and Conservatives, I explained why I don’t care about the migrant children being separated from their families, why I don’t care about the migrants being frisked and checked. Why I don’t care about the migrants that get terminated for attacking the authorities, why I stand against the White liberal and why I chose to do this. It’s hard to see my character and vision through tweets, I’m always thankful for Fresh&Fit giving me a mic to speak. I look forward to collaborating with Flakko and breaking the narrative together.

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442,671 views • 5 months ago

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28,334 views • 8 months ago

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Michael Franzese

24,288 views • 11 months ago

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👉M-Û-R-Č-H👈

29,559 views • 3 months ago

so have we discussed this already or not? but what do we think about this vr game considering that everything in it is connected to byler one way or another and i’m wondering why…

so have we discussed this already or not? but what do we think about this vr game considering that everything in it is connected to byler one way or another and i’m wondering why…

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300,377 views • 6 months ago

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The Bossticks

10,406 views • 1 year ago

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138,908 views • 1 year ago

With all the talk about graphene in the past, it makes you wonder what else they would do to try to get people to ingest it. And why? Graphene can harm you in many ways. But I’m not sure the powers that be care about your health. God bless

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Harry Fisher

30,345 views • 2 years ago

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16,853 views • 1 year ago

Dr. Aseem Malhotra exposes statins: A 1% benefit with hidden costs—time for informed consent Dr. Aseem Malhotra, a renowned cardiologist, has raised critical concerns about statins, one of the most prescribed drugs globally, with 30 million users in the U.S. and up to a billion worldwide. In a recent discussion, he unpacked the shocking truth about their efficacy, urging patients to question the widespread use of these cholesterol-lowering medications. Drawing from industry-sponsored trial data, Dr. Malhotra highlights that for most people—those not at high risk of heart attack—taking a statin daily for five years offers just a 1% chance of preventing a non-fatal heart attack or non-disabling stroke. Critically, this comes with no evidence of prolonging life by even a single day. He emphasizes that this information, available at is rarely communicated to patients due to systemic gaps in medical training, where doctors are not taught to interpret and convey such data effectively. Dr. Malhotra advocates for informed consent, presenting patients with these facts without coercion. Many, he notes, are dismayed by the minimal benefit when weighed against potential side effects, which affect 20-50% of users. These include muscle pain, fatigue, brain fog, erectile dysfunction, joint pain, and stomach issues. Strikingly, he has witnessed elderly patients misdiagnosed with dementia or frailty regain memory and vitality weeks after discontinuing statins. This is not a call to stop medication abruptly, but a plea for patients to engage in informed discussions with their doctors. Dr. Malhotra’s book, A Statin-Free Life, available on Amazon, delves deeper into these findings, offering a comprehensive resource for those seeking clarity on cholesterol management and drug benefits. For evidence-based insights on statins and other medications, visit Dr. Malhotra’s mission is clear: empower patients with knowledge to make health decisions that align with their values and quality of life.

Dr. Aseem Malhotra exposes statins: A 1% benefit with hidden costs—time for informed consent Dr. Aseem Malhotra, a renowned cardiologist, has raised critical concerns about statins, one of the most prescribed drugs globally, with 30 million users in the U.S. and up to a billion worldwide. In a recent discussion, he unpacked the shocking truth about their efficacy, urging patients to question the widespread use of these cholesterol-lowering medications. Drawing from industry-sponsored trial data, Dr. Malhotra highlights that for most people—those not at high risk of heart attack—taking a statin daily for five years offers just a 1% chance of preventing a non-fatal heart attack or non-disabling stroke. Critically, this comes with no evidence of prolonging life by even a single day. He emphasizes that this information, available at is rarely communicated to patients due to systemic gaps in medical training, where doctors are not taught to interpret and convey such data effectively. Dr. Malhotra advocates for informed consent, presenting patients with these facts without coercion. Many, he notes, are dismayed by the minimal benefit when weighed against potential side effects, which affect 20-50% of users. These include muscle pain, fatigue, brain fog, erectile dysfunction, joint pain, and stomach issues. Strikingly, he has witnessed elderly patients misdiagnosed with dementia or frailty regain memory and vitality weeks after discontinuing statins. This is not a call to stop medication abruptly, but a plea for patients to engage in informed discussions with their doctors. Dr. Malhotra’s book, A Statin-Free Life, available on Amazon, delves deeper into these findings, offering a comprehensive resource for those seeking clarity on cholesterol management and drug benefits. For evidence-based insights on statins and other medications, visit Dr. Malhotra’s mission is clear: empower patients with knowledge to make health decisions that align with their values and quality of life.

Camus

107,694 views • 1 year ago