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Supplementing with protein during strength training can increase gains in muscle size by approximately 27%, even when baseline protein intake is already considered adequate. The current RDA for protein, 0.8 grams per kilogram of body weight per day, is meant to prevent deficiency, not to optimize muscle growth or...

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Dr. Rhonda Patrick

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92,581 views • 10 months ago •via X (Twitter)

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More protein does not necessarily mean more muscle. For most people doing resistance training, gains in muscle and strength appear to plateau around 1.6 g/kg/day. But there’s a good reason to push protein higher when the goal is fat loss or body recomposition. Higher protein intake can: - increase satiety and make a calorie deficit easier to sustain - help preserve lean mass so more of the weight lost comes from fat - modestly increase energy expenditure through the thermic effect of food This often gets lost in debates about “optimal” protein intake. You may not need more than ~1.6 g/kg/day to maximize muscle growth, but higher intakes can still be useful when you’re trying to lose fat without losing muscle.
1:13

More protein does not necessarily mean more muscle. For most people doing resistance training, gains in muscle and strength appear to plateau around 1.6 g/kg/day. But there’s a good reason to push protein higher when the goal is fat loss or body recomposition. Higher protein intake can: - increase satiety and make a calorie deficit easier to sustain - help preserve lean mass so more of the weight lost comes from fat - modestly increase energy expenditure through the thermic effect of food This often gets lost in debates about “optimal” protein intake. You may not need more than ~1.6 g/kg/day to maximize muscle growth, but higher intakes can still be useful when you’re trying to lose fat without losing muscle.

Dr. Rhonda Patrick

84,410 views • 2 days ago

Muscle strength is arguably one of the most important predictors of healthspan and longevity—far more than muscle mass alone. Low muscle strength is associated with a 50% higher risk of early death. The good news is that strength can be regained at any age through resistance training, even in your 90s. One study showed that 90-year-old participants increased their strength by 174%, walking speed by 48%, and thigh muscle mass by 9% after just 8 weeks of high-intensity resistance training (PMID: 2342214). This highlights that age-related strength loss is primarily a reversible decline in muscle quality—not just lost muscle mass. But there’s another key piece: protein. For older adults, consuming about 1.6g/kg of body weight in protein daily has been shown to maximize gains in both muscle strength and mass. Combining resistance training with adequate protein intake is a game-changer for improving biological resilience, mobility, and overall quality of life as we age. I cover all this and more in Episode 97: The Science of Protein. It’s a must-watch for anyone looking to improve their health or help loved ones do the same. Watch Episode 97 now:
0:32

Muscle strength is arguably one of the most important predictors of healthspan and longevity—far more than muscle mass alone. Low muscle strength is associated with a 50% higher risk of early death. The good news is that strength can be regained at any age through resistance training, even in your 90s. One study showed that 90-year-old participants increased their strength by 174%, walking speed by 48%, and thigh muscle mass by 9% after just 8 weeks of high-intensity resistance training (PMID: 2342214). This highlights that age-related strength loss is primarily a reversible decline in muscle quality—not just lost muscle mass. But there’s another key piece: protein. For older adults, consuming about 1.6g/kg of body weight in protein daily has been shown to maximize gains in both muscle strength and mass. Combining resistance training with adequate protein intake is a game-changer for improving biological resilience, mobility, and overall quality of life as we age. I cover all this and more in Episode 97: The Science of Protein. It’s a must-watch for anyone looking to improve their health or help loved ones do the same. Watch Episode 97 now:

Dr. Rhonda Patrick

83,710 views • 1 year ago

Simply increasing protein intake to 1.2 g/kg (~0.55 g/lb) per day can nearly eliminate age-related muscle loss in older adults In older women specifically, this reduces the risk of developing frailty by 30% It's time the outdated RDA of 0.8 g/kg per day be revised upward 1.2 g/kg should become the new minimum
1:20

Simply increasing protein intake to 1.2 g/kg (~0.55 g/lb) per day can nearly eliminate age-related muscle loss in older adults In older women specifically, this reduces the risk of developing frailty by 30% It's time the outdated RDA of 0.8 g/kg per day be revised upward 1.2 g/kg should become the new minimum

FoundMyFitness Clips

46,552 views • 9 months ago

How to optimize protein and carbohydrate intake for muscle growth and recovery, according to Andy Galpin, PhD: – Total daily protein target: 1g per pound of body weight (2.2g per kg). Stay at or above this number. Protein timing and quality matter far less. – For strength training: aim for a 1:1 protein to carbohydrate ratio around your workout (roughly 35g protein and 35g carbohydrates). – For hard conditioning workouts: shift to a 3:1 or 4:1 carbohydrate to protein ratio (roughly 35g protein and 100 to 140g carbohydrates). – For a mixed strength and conditioning session: a 2:1 carbohydrate to protein ratio is the target (roughly 35g protein and 60 to 70g carbohydrates). – Timing is flexible: nutrients can be consumed pre, mid or post workout. What matters most is that they are consumed close to training. Andrew D. Huberman, Ph.D.
7:30

How to optimize protein and carbohydrate intake for muscle growth and recovery, according to Andy Galpin, PhD: – Total daily protein target: 1g per pound of body weight (2.2g per kg). Stay at or above this number. Protein timing and quality matter far less. – For strength training: aim for a 1:1 protein to carbohydrate ratio around your workout (roughly 35g protein and 35g carbohydrates). – For hard conditioning workouts: shift to a 3:1 or 4:1 carbohydrate to protein ratio (roughly 35g protein and 100 to 140g carbohydrates). – For a mixed strength and conditioning session: a 2:1 carbohydrate to protein ratio is the target (roughly 35g protein and 60 to 70g carbohydrates). – Timing is flexible: nutrients can be consumed pre, mid or post workout. What matters most is that they are consumed close to training. Andrew D. Huberman, Ph.D.

Huberman Lab Clips

12,950 views • 3 months ago

On average, most people lose 1% of their muscle mass per year and 3% of their strength per year after age 50. It's even worse if you're inactive—strength drops by 4% annually in people who don't engage in resistance exercise! Strength training and a high protein intake can slow or mitigate age-related declines in muscle, and this is important. More muscle enhances metabolism, improves insulin sensitivity, and protects against diabetes. But muscle also safeguards against falls and fractures, which can be a literal death sentence for older adults— up to 58% of older adults who experience a hip fracture die within 12 months of the injury. The evidence is clear: more muscle lowers mortality risk, while less muscle and a higher fat mass increases it. And while resistance exercise is the most important factor for building and maintaining muscle, optimizing protein intake is a proven strategy to increase healthspan at every age. Discover the optimal protein intake tailored to your age, physical activity, and goals in my new episode, The Science of Protein (Episode 97), now available on all major platforms. Watch now:
1:26

On average, most people lose 1% of their muscle mass per year and 3% of their strength per year after age 50. It's even worse if you're inactive—strength drops by 4% annually in people who don't engage in resistance exercise! Strength training and a high protein intake can slow or mitigate age-related declines in muscle, and this is important. More muscle enhances metabolism, improves insulin sensitivity, and protects against diabetes. But muscle also safeguards against falls and fractures, which can be a literal death sentence for older adults— up to 58% of older adults who experience a hip fracture die within 12 months of the injury. The evidence is clear: more muscle lowers mortality risk, while less muscle and a higher fat mass increases it. And while resistance exercise is the most important factor for building and maintaining muscle, optimizing protein intake is a proven strategy to increase healthspan at every age. Discover the optimal protein intake tailored to your age, physical activity, and goals in my new episode, The Science of Protein (Episode 97), now available on all major platforms. Watch now:

Dr. Rhonda Patrick

124,040 views • 1 year ago

Most people don't need more protein to build muscle. They need to train more. Protein isn’t the main driver of adaptation, training is. Muscle growth, strength, and metabolic health are primarily stimulated by mechanical tension and progressive overload, not just a higher protein intake. Protein’s role is supportive. It helps repair and build after you’ve given your body a reason to adapt. But without a meaningful training stimulus, more protein doesn’t translate into better outcomes (e.g., more strength, greater lean mass).
0:30

Most people don't need more protein to build muscle. They need to train more. Protein isn’t the main driver of adaptation, training is. Muscle growth, strength, and metabolic health are primarily stimulated by mechanical tension and progressive overload, not just a higher protein intake. Protein’s role is supportive. It helps repair and build after you’ve given your body a reason to adapt. But without a meaningful training stimulus, more protein doesn’t translate into better outcomes (e.g., more strength, greater lean mass).

Dr. Rhonda Patrick

218,749 views • 5 months ago

Eating protein before bed may improve muscle mass and aid recovery — if you lift weights. In the evening, especially in the hours before bed, our bodies are at their least insulin-sensitive. As melatonin levels rise, it interacts with receptors in the pancreas, signaling a reduction in insulin secretion. However, for the purposes of maximizing our adaptive response to resistance training, sleep is a period of long unbroken fasting. Evidence shows that during exercise training, consuming 30 grams of protein before enhances gains in muscle mass and strength. There’s two ways to look at this: One way is through the lens of time-restricted eating and the other is through the lens of actively optimizing for muscle protein synthesis on training days. Pre-sleep protein is just one way to increase total daily protein intake. A low-calorie protein shake on training days can support muscle growth by enhancing protein synthesis. However, keep in mind the natural drop in insulin sensitivity near bedtime, especially on non-training days when exercise isn’t boosting insulin sensitivity. Learn more by tuning into the Science of Protein podcast, available now on all major platforms. Show notes:
1:14

Eating protein before bed may improve muscle mass and aid recovery — if you lift weights. In the evening, especially in the hours before bed, our bodies are at their least insulin-sensitive. As melatonin levels rise, it interacts with receptors in the pancreas, signaling a reduction in insulin secretion. However, for the purposes of maximizing our adaptive response to resistance training, sleep is a period of long unbroken fasting. Evidence shows that during exercise training, consuming 30 grams of protein before enhances gains in muscle mass and strength. There’s two ways to look at this: One way is through the lens of time-restricted eating and the other is through the lens of actively optimizing for muscle protein synthesis on training days. Pre-sleep protein is just one way to increase total daily protein intake. A low-calorie protein shake on training days can support muscle growth by enhancing protein synthesis. However, keep in mind the natural drop in insulin sensitivity near bedtime, especially on non-training days when exercise isn’t boosting insulin sensitivity. Learn more by tuning into the Science of Protein podcast, available now on all major platforms. Show notes:

Dr. Rhonda Patrick

92,595 views • 1 year ago

Older adults need twice as much protein per meal as younger adults to get the same amount of muscle protein synthesis. That's because muscles become less sensitive to amino acids in response to protein intake, a phenomenon known as anabolic resistance. Most people think this is due to aging, but physical inactivity is the real culprit. People are less active as they get older. Only about 30% of young adults and just 20% of older adults regularly engage in some form of resistance training. Older adults who stay physically active or who engage in resistance exercise right before consuming protein don't experience anabolic resistance. Their anabolic response is identical to that of younger adults. How do I interpret this? If you're older, you might need a higher daily and per-meal protein dose (30–40 grams versus 20–30 grams for someone younger) to maximize muscle protein synthesis and increase or maintain muscle mass. But it also means that staying physically active and strength training often is the key to preventing "age-related" anabolic resistance. It's not inevitable.
1:02

Older adults need twice as much protein per meal as younger adults to get the same amount of muscle protein synthesis. That's because muscles become less sensitive to amino acids in response to protein intake, a phenomenon known as anabolic resistance. Most people think this is due to aging, but physical inactivity is the real culprit. People are less active as they get older. Only about 30% of young adults and just 20% of older adults regularly engage in some form of resistance training. Older adults who stay physically active or who engage in resistance exercise right before consuming protein don't experience anabolic resistance. Their anabolic response is identical to that of younger adults. How do I interpret this? If you're older, you might need a higher daily and per-meal protein dose (30–40 grams versus 20–30 grams for someone younger) to maximize muscle protein synthesis and increase or maintain muscle mass. But it also means that staying physically active and strength training often is the key to preventing "age-related" anabolic resistance. It's not inevitable.

Dr. Rhonda Patrick

84,167 views • 10 months ago

High‑protein diets do not harm your kidneys, even in people with impaired kidney function A 2024 study of adults with and without chronic kidney disease found that higher protein intake wasn’t just safe... It was associated with progressively lower mortality, up to ~33% lower risk at ~1.6 g/kg/day compared to the RDA Even in the most extreme cases, such as very sick patients receiving high-dose IV protein directly into their veins, research finds no signal of kidney harm For typical healthy adults who exercise and want to age well, the real danger isn’t eating “too much” protein, but eating too little, not training enough, and slowly losing muscle and resilience year after year
2:26

High‑protein diets do not harm your kidneys, even in people with impaired kidney function A 2024 study of adults with and without chronic kidney disease found that higher protein intake wasn’t just safe... It was associated with progressively lower mortality, up to ~33% lower risk at ~1.6 g/kg/day compared to the RDA Even in the most extreme cases, such as very sick patients receiving high-dose IV protein directly into their veins, research finds no signal of kidney harm For typical healthy adults who exercise and want to age well, the real danger isn’t eating “too much” protein, but eating too little, not training enough, and slowly losing muscle and resilience year after year

FoundMyFitness Clips

76,318 views • 8 months ago

New episode on the science of protein. Protein is fundamental to our survival, fueling the processes that build, repair, and maintain every tissue in the body—including the brain. But how much is truly optimal, and are there risks to consuming too much? By the end of this episode, you'll have evidence-based tools to leverage protein for muscle, performance, and longevity. Episode 97 available now on X, YouTube, Spotify, and Apple Podcasts. Timestamps: 0:00 - Introduction 2:47 - Why muscle matters 5:12 - Why do we lose muscle? 6:46 - Negating anabolic resistance 7:39 - Why it's never too late to build muscle 8:20 - Requirements for overweight individuals 9:07 - Flaws of the RDA 10:27 - Optimal intake when resistance training 11:10 - What to do when losing weight 12:23 - Does protein harm healthy kidneys? 14:14 - How important is distribution? 16:26 - Debunking the "anabolic window" 18:03 - Benefits of pre-sleep intake 19:35 - Timing & distribution takeaways 20:16 - What are the best sources? 23:20 - Animal vs. plant protein 25:42 - Protein supplements 27:12 - Does high intake accelerate aging? 30:47 - Why exercise changes the story 33:17 - What we can learn from athletes 33:51 - Does high intake promote atherosclerosis? 36:06 - 8 key takeaways
40:09

New episode on the science of protein. Protein is fundamental to our survival, fueling the processes that build, repair, and maintain every tissue in the body—including the brain. But how much is truly optimal, and are there risks to consuming too much? By the end of this episode, you'll have evidence-based tools to leverage protein for muscle, performance, and longevity. Episode 97 available now on X, YouTube, Spotify, and Apple Podcasts. Timestamps: 0:00 - Introduction 2:47 - Why muscle matters 5:12 - Why do we lose muscle? 6:46 - Negating anabolic resistance 7:39 - Why it's never too late to build muscle 8:20 - Requirements for overweight individuals 9:07 - Flaws of the RDA 10:27 - Optimal intake when resistance training 11:10 - What to do when losing weight 12:23 - Does protein harm healthy kidneys? 14:14 - How important is distribution? 16:26 - Debunking the "anabolic window" 18:03 - Benefits of pre-sleep intake 19:35 - Timing & distribution takeaways 20:16 - What are the best sources? 23:20 - Animal vs. plant protein 25:42 - Protein supplements 27:12 - Does high intake accelerate aging? 30:47 - Why exercise changes the story 33:17 - What we can learn from athletes 33:51 - Does high intake promote atherosclerosis? 36:06 - 8 key takeaways

Dr. Rhonda Patrick

141,365 views • 1 year ago

Up to 30% of the weight lost while dieting can come from lean muscle mass—but the right training and nutrition can help you preserve muscle, which is key for metabolic health and reducing the risk of sarcopenia. You can lose fat and gain muscle at the same time—a process called body recomposition—if you train and eat strategically. The most important factor is resistance training. Lifting heavy 2–3 times per week is essential for maintaining and building muscle while losing fat. Without it, muscle mass inevitably declines. Nutrition also plays a major role. Eating in a slight calorie deficit—around 10–20% below maintenance—allows for steady fat loss without sacrificing muscle, energy levels, or training performance. Protein intake is another key priority. Research shows that consuming 1.8 to 2.2 grams of protein per kilogram of body weight per day is optimal for muscle retention and growth during a calorie deficit, and going even higher may provide additional benefits. Beyond training and nutrition, recovery is just as crucial. Adequate sleep, stress management, and tracking progress help ensure you’re making real, sustainable changes. Get this right and you have a powerful strategy to build muscle and lose fat. If you want to learn more about optimizing body recomposition, improving VO2 max, and enhancing brain health, tune into the latest episode of the FoundMyFitness podcast, where and I break it all down with insights from top experts. Link to the full episode on YouTube:
3:56

Up to 30% of the weight lost while dieting can come from lean muscle mass—but the right training and nutrition can help you preserve muscle, which is key for metabolic health and reducing the risk of sarcopenia. You can lose fat and gain muscle at the same time—a process called body recomposition—if you train and eat strategically. The most important factor is resistance training. Lifting heavy 2–3 times per week is essential for maintaining and building muscle while losing fat. Without it, muscle mass inevitably declines. Nutrition also plays a major role. Eating in a slight calorie deficit—around 10–20% below maintenance—allows for steady fat loss without sacrificing muscle, energy levels, or training performance. Protein intake is another key priority. Research shows that consuming 1.8 to 2.2 grams of protein per kilogram of body weight per day is optimal for muscle retention and growth during a calorie deficit, and going even higher may provide additional benefits. Beyond training and nutrition, recovery is just as crucial. Adequate sleep, stress management, and tracking progress help ensure you’re making real, sustainable changes. Get this right and you have a powerful strategy to build muscle and lose fat. If you want to learn more about optimizing body recomposition, improving VO2 max, and enhancing brain health, tune into the latest episode of the FoundMyFitness podcast, where and I break it all down with insights from top experts. Link to the full episode on YouTube:

Dr. Rhonda Patrick

120,402 views • 1 year ago

8 key takeaways on protein intake: 1) Most people should consume 1.2-1.6 g/kg (0.54-0.72 g/lb) per day, and calculate needs based on lean body mass 2) The post-exercise "anabolic window" isn't as narrow as once believed — total daily intake matters far more than exact timing around workouts 3) Try to distribute protein evenly across the day (but again, total daily intake is much more important) 4) Pre-sleep protein intake (~30g) can be beneficial, especially for older adults and athletes 5) High-quality supplements like whey and casein proteins offer targeted benefits (and even if you meet your protein needs through diet, supplementation can provide additional advantages) 6) Animal proteins are generally superior to plant proteins for maximizing muscle protein synthesis 7) Concerns about high protein intake harming healthy kidneys are largely unfounded 8) High protein intake doesn't reduce longevity or promote cancer growth if you exercise (exercise helps direct amino acids and growth factors toward beneficial uses)
3:20

8 key takeaways on protein intake: 1) Most people should consume 1.2-1.6 g/kg (0.54-0.72 g/lb) per day, and calculate needs based on lean body mass 2) The post-exercise "anabolic window" isn't as narrow as once believed — total daily intake matters far more than exact timing around workouts 3) Try to distribute protein evenly across the day (but again, total daily intake is much more important) 4) Pre-sleep protein intake (~30g) can be beneficial, especially for older adults and athletes 5) High-quality supplements like whey and casein proteins offer targeted benefits (and even if you meet your protein needs through diet, supplementation can provide additional advantages) 6) Animal proteins are generally superior to plant proteins for maximizing muscle protein synthesis 7) Concerns about high protein intake harming healthy kidneys are largely unfounded 8) High protein intake doesn't reduce longevity or promote cancer growth if you exercise (exercise helps direct amino acids and growth factors toward beneficial uses)

FoundMyFitness Clips

96,871 views • 1 year ago

Protein timing and distribution are important, but not more important than simply eating enough protein. This doesn’t mean timing is irrelevant. Spreading protein relatively evenly across the day is a reasonable strategy for maximizing opportunities to stimulate muscle protein synthesis. But emerging evidence challenges the idea that the body can only “use” 25-30 grams of protein at a time. In one study, researchers compared 25 g vs. 100 g of protein after exercise. The 100-g dose produced a greater and more prolonged increase in muscle protein synthesis, with very little of the additional amino acids being oxidized. The extra protein wasn’t simply “wasted.” Larger protein meals take longer to digest and absorb, extending the period during which amino acids are available to support tissue protein synthesis. Practically, consuming your daily protein across 2-3 larger meals is not inherently inferior simply because individual meals contain far more than 25-30 grams.
1:42

Protein timing and distribution are important, but not more important than simply eating enough protein. This doesn’t mean timing is irrelevant. Spreading protein relatively evenly across the day is a reasonable strategy for maximizing opportunities to stimulate muscle protein synthesis. But emerging evidence challenges the idea that the body can only “use” 25-30 grams of protein at a time. In one study, researchers compared 25 g vs. 100 g of protein after exercise. The 100-g dose produced a greater and more prolonged increase in muscle protein synthesis, with very little of the additional amino acids being oxidized. The extra protein wasn’t simply “wasted.” Larger protein meals take longer to digest and absorb, extending the period during which amino acids are available to support tissue protein synthesis. Practically, consuming your daily protein across 2-3 larger meals is not inherently inferior simply because individual meals contain far more than 25-30 grams.

Dr. Rhonda Patrick

56,184 views • 11 days ago

How to lose fat and gain muscle at the same time: – Keep calories 10% above maintenance, roughly 200 to 300 calories over. The surplus should come primarily from quality protein. – Protein is the key variable: aim for 1 to 1.5 grams per pound of body weight. Studies show that adding 80 to 100 grams of protein on top of habitual intake leads to fat loss, not fat gain. – Distribution of protein throughout the day matters less than hitting the total daily target. Alan Aragon on the Andrew D. Huberman, Ph.D. podcast
8:39

How to lose fat and gain muscle at the same time: – Keep calories 10% above maintenance, roughly 200 to 300 calories over. The surplus should come primarily from quality protein. – Protein is the key variable: aim for 1 to 1.5 grams per pound of body weight. Studies show that adding 80 to 100 grams of protein on top of habitual intake leads to fat loss, not fat gain. – Distribution of protein throughout the day matters less than hitting the total daily target. Alan Aragon on the Andrew D. Huberman, Ph.D. podcast

Huberman Lab Clips

262,914 views • 3 months ago

Protein catalyzes nearly every biochemical reaction in our bodies, making it indispensable for life. Every day, our bodies renew and replace around 300 grams of protein – the same weight as a can of Campbell's chicken soup. In today's FoundMyFitness episode, Dr. Luc van Loon joins me to shatter myths about protein intake and muscle protein synthesis. His research showed we can utilize up to 100 grams of protein in one meal, far more than previously thought. We also dive into how to distribute protein optimally across the day, the top sources, and strategies to ward off anabolic resistance—a state where muscles dial down their response to protein and exercise. Timestamps: 0:00 - Introduction 1:16 - Why do we need protein? 2:20 - How the protein RDA (0.8 g/kg) was established 6:50 - Protein turnover in organs (brain, liver, etc.) 10:10 - How much protein do you really need? 14:58 - Protein intake when dieting for weight loss 16:15 - How the body adapts to higher protein 19:46 - Anabolic resistance 22:45 - Protein requirements for overweight individuals 24:58 - Gaining strength vs. muscle mass 29:20 - Optimal protein distribution 33:05 - 20g vs. 100g protein post-workout 36:01 - Can evening protein consumption stimulate MPS overnight? 40:45 - How does time-restricted feeding affect MPS? 47:07 - Protein before vs. after exercising 48:57 - How does spreading out protein intake affect hypertrophy? 51:55 - Protein shakes vs. animal protein 54:58 - Protein supplementation for weight loss & recomposition 56:14 - Casein vs. whey protein 59:09 - Factors that influence protein's anabolic potential 1:00:14 - Raw eggs vs. cooked — what's better for hypertrophy? 1:04:07 - Plant vs. animal protein 1:07:08 - Plant-based protein powder 1:11:47 - Whey protein isolate vs. concentrate 1:12:36 - Resistance training & the leucine threshold 1:15:47 - Do high-protein diets cause atherosclerosis? 1:23:45 - Muscle memory & resistance training 1:26:25 - Optimal resistance training frequency 1:28:22 - Advice for elderly who want to start resistance training 1:30:49 - Hormonal changes & resistance training 1:36:09 - Does cold-water immersion blunt gains? 1:45:19 - Hydrolyzed collagen powder 1:53:01 - Signaling roles of collagen peptides 1:55:31 - How hydrolyzed collagen powder affects pain perception 1:56:53 - Benefits of smaller peptides in hydrolyzed collagen 1:58:57 - Collagen's impact on skin health 2:02:46 - Amino acids from hydrolyzed collagen powder 2:07:30 - Luc's exercise routine & diet
2:09:29

Protein catalyzes nearly every biochemical reaction in our bodies, making it indispensable for life. Every day, our bodies renew and replace around 300 grams of protein – the same weight as a can of Campbell's chicken soup. In today's FoundMyFitness episode, Dr. Luc van Loon joins me to shatter myths about protein intake and muscle protein synthesis. His research showed we can utilize up to 100 grams of protein in one meal, far more than previously thought. We also dive into how to distribute protein optimally across the day, the top sources, and strategies to ward off anabolic resistance—a state where muscles dial down their response to protein and exercise. Timestamps: 0:00 - Introduction 1:16 - Why do we need protein? 2:20 - How the protein RDA (0.8 g/kg) was established 6:50 - Protein turnover in organs (brain, liver, etc.) 10:10 - How much protein do you really need? 14:58 - Protein intake when dieting for weight loss 16:15 - How the body adapts to higher protein 19:46 - Anabolic resistance 22:45 - Protein requirements for overweight individuals 24:58 - Gaining strength vs. muscle mass 29:20 - Optimal protein distribution 33:05 - 20g vs. 100g protein post-workout 36:01 - Can evening protein consumption stimulate MPS overnight? 40:45 - How does time-restricted feeding affect MPS? 47:07 - Protein before vs. after exercising 48:57 - How does spreading out protein intake affect hypertrophy? 51:55 - Protein shakes vs. animal protein 54:58 - Protein supplementation for weight loss & recomposition 56:14 - Casein vs. whey protein 59:09 - Factors that influence protein's anabolic potential 1:00:14 - Raw eggs vs. cooked — what's better for hypertrophy? 1:04:07 - Plant vs. animal protein 1:07:08 - Plant-based protein powder 1:11:47 - Whey protein isolate vs. concentrate 1:12:36 - Resistance training & the leucine threshold 1:15:47 - Do high-protein diets cause atherosclerosis? 1:23:45 - Muscle memory & resistance training 1:26:25 - Optimal resistance training frequency 1:28:22 - Advice for elderly who want to start resistance training 1:30:49 - Hormonal changes & resistance training 1:36:09 - Does cold-water immersion blunt gains? 1:45:19 - Hydrolyzed collagen powder 1:53:01 - Signaling roles of collagen peptides 1:55:31 - How hydrolyzed collagen powder affects pain perception 1:56:53 - Benefits of smaller peptides in hydrolyzed collagen 1:58:57 - Collagen's impact on skin health 2:02:46 - Amino acids from hydrolyzed collagen powder 2:07:30 - Luc's exercise routine & diet

Dr. Rhonda Patrick

153,330 views • 2 years ago

How much muscle you have predicts how well you’ll age better than body weight or BMI ever could After age 50, the average person loses about 1% of their muscle mass every single year And strength declines even faster—plummeting 3% annually The good news? Resistance training and dialing in your protein intake can slow, stop, or even reverse this decline—and it’s never too late to start
1:23

How much muscle you have predicts how well you’ll age better than body weight or BMI ever could After age 50, the average person loses about 1% of their muscle mass every single year And strength declines even faster—plummeting 3% annually The good news? Resistance training and dialing in your protein intake can slow, stop, or even reverse this decline—and it’s never too late to start

FoundMyFitness Clips

38,939 views • 1 year ago

🔥The Untold SECRET To Muscle Growth 🔥 Most people think … Eating mountains of protein is the fastest way to build muscle. While in reality this is completely WRONG Because if you WANT to actually build MORE muscles You NEED the right trigger to switch on muscle growth. That trigger is Leucine This powerhouse amino acid … Is the SWITCH that turns on muscle protein synthesis The process that actually grows your muscles. And to make it WORK for you : ⚡️ Aim for 2–3g of leucine per meal ⚡ Hit that target across 3 solid meals a day ⚡ Watch your recovery, strength, and size MOVE to the next level Coz… Protein alone = building blocks. Leucine = the builder. Without the builder…. the building will never be built Curious… Which meal of the day do YOU think gives the most leucine? …Comment below 👇
0:28

🔥The Untold SECRET To Muscle Growth 🔥 Most people think … Eating mountains of protein is the fastest way to build muscle. While in reality this is completely WRONG Because if you WANT to actually build MORE muscles You NEED the right trigger to switch on muscle growth. That trigger is Leucine This powerhouse amino acid … Is the SWITCH that turns on muscle protein synthesis The process that actually grows your muscles. And to make it WORK for you : ⚡️ Aim for 2–3g of leucine per meal ⚡ Hit that target across 3 solid meals a day ⚡ Watch your recovery, strength, and size MOVE to the next level Coz… Protein alone = building blocks. Leucine = the builder. Without the builder…. the building will never be built Curious… Which meal of the day do YOU think gives the most leucine? …Comment below 👇

Alex Stanciu

15,337 views • 11 months ago

There is now converging evidence in animals and humans that omega-3 fatty acids are at the least anti-catabolic and, likely, anabolic. They seem to do this by shifting the balance away from breakdown and more towards muscle building, particularly in the context of anabolic resistance. Animal studies show omega-3 fatty acids augment muscle development: Steers fed omega-3s showed improved amino acid efficiency and activated pathways involved in muscle growth. Similarly, pigs given a high omega-3 diet exhibited larger muscles and markers of improved amino acid absorption and use. But more importantly, we have human evidence: • In one study, young women taking 5 grams of omega-3s per day cut their muscle loss almost in half and increased muscle protein synthesis after two weeks of leg immobilization. • In another study, older adults consuming 3.36 grams of omega-3s daily for two months had an increase in muscle protein synthesis in the presence of amino acids and insulin. • Yet another study found that healthy older adults taking 4 grams of omega-3s daily for half a year increased various measures of muscle size and strength. • Still another study, older adults who consumed 4 grams of krill oil daily for six months improved knee strength, grip strength, thigh muscle thickness, and measures of muscle nerve response. There are still open questions. For example, a consistent theme is that many of the studies are high dose at 4 and 5 grams per day - does that imply that these effects in muscle only happen at high dosages? Another question we might ask is, in what context is omega-3 more anabolic - for example, in old age? During immobilization? When protein intake is sub-optimal for muscle building? (It often is for many of us.) Listen to my recent podcast guest Dr. Chris McGlory for more discussion of this fascinating new emerging field. Show notes and transcript for this episode here:
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There is now converging evidence in animals and humans that omega-3 fatty acids are at the least anti-catabolic and, likely, anabolic. They seem to do this by shifting the balance away from breakdown and more towards muscle building, particularly in the context of anabolic resistance. Animal studies show omega-3 fatty acids augment muscle development: Steers fed omega-3s showed improved amino acid efficiency and activated pathways involved in muscle growth. Similarly, pigs given a high omega-3 diet exhibited larger muscles and markers of improved amino acid absorption and use. But more importantly, we have human evidence: • In one study, young women taking 5 grams of omega-3s per day cut their muscle loss almost in half and increased muscle protein synthesis after two weeks of leg immobilization. • In another study, older adults consuming 3.36 grams of omega-3s daily for two months had an increase in muscle protein synthesis in the presence of amino acids and insulin. • Yet another study found that healthy older adults taking 4 grams of omega-3s daily for half a year increased various measures of muscle size and strength. • Still another study, older adults who consumed 4 grams of krill oil daily for six months improved knee strength, grip strength, thigh muscle thickness, and measures of muscle nerve response. There are still open questions. For example, a consistent theme is that many of the studies are high dose at 4 and 5 grams per day - does that imply that these effects in muscle only happen at high dosages? Another question we might ask is, in what context is omega-3 more anabolic - for example, in old age? During immobilization? When protein intake is sub-optimal for muscle building? (It often is for many of us.) Listen to my recent podcast guest Dr. Chris McGlory for more discussion of this fascinating new emerging field. Show notes and transcript for this episode here:

Dr. Rhonda Patrick

190,965 views • 3 years ago