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The 4th & final Arihant-class SSBN, INS Arisudhan, is expected to complete its sea trials by the end of 2026. 🇮🇳☢️ Key highlights- Displacement: 7000 tonnes Indigenous content: 80%+ Powered by: Compact LW reactor (83MW) Can Carry: 24 × K-15 Sagarika/8 × K-4 SLBMs 🎥 For RP

47,549 görüntüleme • 10 gün önce •via X (Twitter)

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🚨🇷🇺 NATO IN PANIC: RUSSIA’S FIRST ZIRCON-ARMED NUCLEAR SUBMARINE IS ENTERING SERVICE Russia’s Project 885M nuclear submarine Perm is expected to complete trials and join the Navy before the end of 2026. It will be Russia’s first multipurpose nuclear submarine built from the outset to carry Zircon hypersonic cruise missiles as standard armament. 🔸 The Yasen-M combines the concealment and endurance of a nuclear-powered attack submarine with Russia’s most advanced naval strike weapons. Its arsenal includes Zircon, Kalibr and Oniks missiles for attacks against warships and targets deep inland. 🔸 The submarine has a submerged displacement of around 13,800 tonnes, reaches 31 knots underwater, can dive to 520 metres and remain at sea for up to 100 days. 🔸 Zircon reaches speeds of around Mach 9 and can strike sea and land targets at ranges exceeding 1,000 km. Its speed leaves defending forces only minutes to detect the launch, identify the target and attempt an interception. 🔸 The missile has already been successfully launched from beneath the surface, but Perm turns that tested capability into the standard armament of an operational submarine rather than a launch from an adapted trial platform. 🔸 Surface ships carrying hypersonic missiles can be tracked by satellites, aircraft and patrol vessels. A Yasen-M can remain hidden beneath the ocean, change its firing position and attack from an unexpected direction. 🔸 The same submarine can hunt carrier groups and other major warships while holding naval bases, ports, command centres and infrastructure on land at risk. Finding Perm will be NATO’s first problem. Stopping its missiles after launch will be the second — and at Mach 9, the alliance may have only minutes to solve it. Does NATO have an answer to a Mach 9 missile launched from beneath the ocean?

NewRulesGeopolitics

29,823 görüntüleme • 1 ay önce

We’ve gone critical. At 12:20 am on July 4th, Aalo sustained a controlled fission chain reaction for the first time. We have officially surpassed the goal of President Trump’s Executive Order 14301, achieving 4 advanced nuclear reactor criticalities by America’s 250th birthday. This is a zero-power criticality to validate our supply chain, reactor physics and control systems for our 10 MWe full-powered reactor, the Aalo-X, targeting power operations next year. Everything was built at full scale: fuel, moderator, control systems, etc., so we understand system performance at its commercial scope. That also meant tackling four of the most difficult things in nuclear with this criticality milestone: ✅ Ground-up construction of our reactor facility ✅ Manufacturing the reactor in our factory and shipping them by road ✅ Assembling our own fuel assemblies using commercial UO2 ✅ Standing up training, safety, and operational programs to become our own nuclear operator I am proud to say we have accomplished all four goals, along with achieving criticality. The reactor building was constructed in 36 days and construction to criticality was achieved in under 8 months. That’s the fastest nuclear build in the last 80 years. A massive congratulations to the Aalo Atomics team and our partners. Many thanks to Idaho National Laboratory, the DOE-Idaho Operations Office, and the Office of Nuclear Energy for their immense support in enabling this milestone and dedicated to the American nuclear resurgence.

Yasir Arafat

99,877 görüntüleme • 1 ay önce

🏆 #FELIX ReawakeR achievements ✰ SPOTIFY : ➺ First Stray Kids member song to reach 100M streams ➺ Most streamed Anime OST by a K-pop idol in Spotify history ➺ Most streamed Anime OST released in 2025 ➺ Most streamed Song by 4th gen male solo artist released in 2025 ➺ Most streamed OST by 4th gen solo artist ➺ 3rd most played Japanese song overseas for the first half of 2025 ➺ 5th most played Japanese song overseas in 2025 ➺ Most streamed Solo Leveling track ➺ Most streamed SKZ solo collab ➺ #4 on Spotify's " Best of Anime now 2025 " ✰ iTunes : ➺ Longest charting Stray Kids song on Worldwide iTunes Song Chart ( 91 days) ➺ Longest charting 2025 male K-pop artist song on the chart ➺ #1 on iTunes Song Charts in 9 countries/regions ✰ Recochoku : ➺ #1 Daily Singles Ranking (2nd skz song to do so) ➺ Highest Stray Kids peak on Recochoku Monthly Singles Ranking (#11) ✰ Billboard : ➺ Longest Charting 2025 song by kpop male act on billboard world digital song sales ( 15 weeks ) ➺ Longest Charting song by 4th gen male kpop act on billboard world digital song sales ( 15 weeks ) ➺ Felix becomes the first K-pop male artist this year to enter Billboard Dance Digital Song Sales ( 11th K-pop male artist to enter the chart ) ➺ FELIX is the first Korean Solo Artist in History to reach #1 on Billboard LyricFind U.S Chart (and joins BTS and Fifty Fifty as the only Korean acts in history to ever top Billboard LyricFind US chart ) ➺ Felix becomes the first male K-pop artist in 2025 to enter the Billboard LyricFind Global chart ✰ Billboard Japan : ➺ Felix becomes the first K-pop artist to reach #1 on various Billboard Japan Songs chart (8 counties) ➺ Felix becomes the first K-pop artist to top Billboard Japan Global Excl. ( 8th song to ever top the chart ) (charted for 8 consecutive weeks at #1 ) ➺ Longest charting song by 4th generation K-pop male artist on Billboard Japan Download Songs (16 weeks) ➺ Longest charting 2025 song by K-pop male artist on Billboard Japan Download Songs (16 weeks) ➺ Ranked #5 on Billboard japan Global Japan Songs excl. Japan ➺ Charted on multiple Billboard japan 2025 mid-year country charts - Japan Songs ( #2 Malaysia, Germany, #3 France, #4 UK, #5 US, South Africa, Brazil, #7 Singapore, #8 Taiwan, #9 India ) ➺ Charted on multiple Billboard japan 2025 year-end charts - Japan Download Songs #64 - Global Excl. Japan #11 - Japan Songs ( #3 France , Germany , #6 South africa < #7 U.S, Brazil, UK, #11 Malaysia, #14 Singapore, India , #15 Taiwan ) ➺ ranks #10 in Billboard Japan 2026 Mid-Year Japan songs Germany chart ✰ YouTube : ➺ Most streamed Solo Leveling Opening MV ➺ Most streamed Stray Kids Japanese MV released in 2025 ➺ Most liked 2025 music videos by 4th gen male soloist ➺ #5 most liked 2025 music videos by K-pop male soloist ( 826K likes ) ✰ YouTube Music : ➺ 100M+ Plays ➺ Most streamed OST by 4th gen male solo artist ➺ Most streamed Solo Leveling Opening ✰ Music Awards Japan : ➺ Nominated for "Best Japanese Song" and "Best Anime Song" at Music Awards Japan 2025 ➺ FELIX becomes the only K-Pop artist to be nominated in "Best Anime Song" at Music Awards Japan ➺ Nominated for "Best Anime Song" at Music Awards Japan 2026 ➺ Felix is the ONLY K-Pop solo artist nominated in this category ➺ Nominated for "Best Global Hit In Japan" and "Best Cross-border Collaboration Song" preliminary nominations at Music Awards Japan 2026 ➺ Nominated for "Best Global Hit In Japan" and "Best Cross-border Collaboration Song" and "Best Japanese Song in Europe " and "Best of Listener’s Choice: Japanese Songs " final nominations at Music Awards Japan 2026 ➺ The only non-virtual K-pop act nominated in a major category "Best Global Hit In Japan" at MUSIC AWARDS JAPAN 2026 ➺ Received the most votes in the first round of voting for “Best Global Hit from Japan,” which was exclusively open to Spotify users outside Japan. ➺ Felix becomes the first 4th-generation solo idol to receive a finalist nomination in a Major Category / Grand prize ✰ QQ Music : ➺ Ranked #1 on QQ Music Peak Chart (Q1 2025 - Anime Category) ✰ Oricon : ➺ The ONLY charting male kpop track in Oricon Top 30 Half-Year Chart 2025 — Digital Singles Track ➺ Peaked at #4 on Oricon Daily Singles Chart ✰ APMA : ➺ Nominated for "Best collaboration" at APMA AWARDS 2025 ✰ Stationhead : ➺#6 most streamed song on stationhead in 2025 ✰ KKBOX 2025 Chart : ➺#1 Japanese Singles for Film & Television ➺#1 Taiwan Most Streamed Japanese Singles ➺#1 HongKong Most Streamed Japanese Singles ➺#2 Singapore Most Streamed Japanese Singles ➺#42 Japan Most Streamed Japanese Singles ✰ Crunchyroll Anime Awards : ➺ Nominated for "Best Opening Sequence" and "Best Anime Song" at Crunchyroll Anime Awards 2026 FELIX REAWAKER 100M CLUB #ReawakeR_100MOnSpotify

Felix 필릭스 Central

20,466 görüntüleme • 2 ay önce

"The last time a major LNG project was developed in this country was 42 years ago, that was a Nigeria LLG project." Nigeria's gas sector has recorded a major breakthrough with the advancement of the $3 billion UTM Floating LNG (FLNG) Project, unlocking stranded offshore gas resources and strengthening the country's drive for industrial growth and energy security. Key Highlights: - The project secured a 15-year gas supply agreement, clearing the path for a Final Investment Decision (FID) expected later this year. - It is Africa's first indigenous-led Floating LNG (FLNG) project, fully developed by a Nigerian company. - The project represents Nigeria's first major LNG development in over 40 years, since the launch of the Nigeria LNG project. - The initiative aligns with President Bola Ahmed Tinubu's gas development agenda, with officials crediting the administration's policy direction for unlocking the project. - A joint venture between NNPC Limited and Seplat Energy will supply 200 million standard cubic feet of gas per day under the 15-year agreement. - The FLNG facility will produce 1.8 million tonnes of LNG annually, monetising stranded gas from the Yoho Field. - About 30% of production, equivalent to over 300,000 metric tonnes of LPG annually, will be supplied to Nigeria's domestic market to support the Federal Government's clean cooking initiative. - The project is expected to generate billions of dollars in revenue, create thousands of jobs, and deepen local participation in the oil and gas industry. - Financing for the project is being led by African Export-Import Bank, which has also provided preparatory funding and is coordinating debt and equity financing. - Project promoters disclosed that the investment is oversubscribed, attracting strong interest from global energy traders and investors, including companies from the Middle East. - The project further demonstrates the growing capacity of indigenous Nigerian companies to deliver large-scale energy infrastructure while positioning Nigeria as a key supplier of LNG to regional and global markets.

Daddy D.O🇳🇬

29,183 görüntüleme • 1 ay önce

🚨🇷🇺OCEANIC SHIELD: RUSSIA'S DOOMSDAY TORPEDO IS NOW AT SEA The Russian Navy has launched its most secretive and strategic submarine yet — RFS Khabarovsk — a nuclear-powered special-purpose vessel built for one mission only: to carry and deploy Poseidon (Status-6) nuclear torpedoes. What is Poseidon? 🔸A nuclear-powered, autonomous underwater torpedo 🔸Estimated range: up to 6,200 miles — intercontinental 🔸Capable of carrying a 2-megaton nuclear warhead — 100x more destructive than the Hiroshima bomb 🔸Runs at depths and speeds that make interception extremely difficult Putin himself confirmed its successful test in October 2025, calling it "a huge success" and saying "there is nothing like this” Khabarovsk — Poseidon's carrier: 🔸A nuclear-powered special-purpose submarine, quietly launched by the Russian Navy 🔸Designed to carry up to 6 Poseidon torpedoes in specialized side-mounted launch hangars 🔸Powered by a single OK-650V nuclear reactor 🔸Operates from protected bastion zones near Russian coastlines — safely out of enemy reach — while Poseidon autonomously travels to its target 🔸No countermeasure exists to intercept it Poseidon is Moscow's direct hedge against US missile defense, precision-strike capabilities, and low-yield nuclear systems that Russia views as a threat to strategic stability. Integrated with the Perimeter dead-hand system, Poseidon guarantees retaliation even if Russia's nuclear command and control is destroyed. Russia's plan, according to the US Naval Institute, calls for 30 Poseidons on 4 submarines — 2 for the Northern Fleet, 2 for the Pacific Fleet — with torpedoes in the Atlantic and Pacific capable of autonomously striking US port cities, far beyond the effective reach of any American torpedo. Multipurpose Deterrent — Poseidon is dual-capable, conventional or nuclear, and built to strike carrier battle groups, coastal fortifications, and critical infrastructure. The US has no standoff weapon to intercept Poseidon. The Navy retired Subroc in 1992 — its only long-range anti-submarine missile. Its replacement, Sea Lance, was canceled at the Cold War's end and never replaced.

NewRulesGeopolitics

56,252 görüntüleme • 3 ay önce

🚨🇷🇺 NATO IN PANIC: RUSSIA COMPLETES SEA TRIALS OF WORLD’S LARGEST AND MOST HEAVILY ARMED CRUISER Russia’s rebuilt Admiral Nakhimov nuclear-powered battlecruiser is finishing factory and sea trials before moving to state testing. Sevmash plans to hand the ship to the Russian Navy by the end of 2026. After nearly three decades away from operational service, the giant warship is returning as a mobile missile arsenal built for prolonged deployments in the Arctic and North Atlantic. 🔸 Scale: At 251 metres and roughly 28,000 tons fully loaded, Admiral Nakhimov is one of the world’s largest non-carrier surface warships. 🔸 Endurance: Two KN-3 nuclear reactors feed steam turbines generating about 140,000 shaft horsepower. Nuclear propulsion provides exceptional cruising range, while the ship’s reported top speed is approximately 32 knots. 🔸 Strike power: The cruiser is expected to carry 80 universal vertical-launch cells able to fire Kalibr cruise missiles, Oniks anti-ship missiles and Zircon hypersonic missiles. The same ship can therefore strike surface vessels and land targets at long range. 🔸 Air defense: Reports indicate a 96-cell long-range air-defense battery backed by Pantsir-M close-in systems. Combined with the strike launchers, this gives the cruiser a reported core arsenal of 176 large missile cells. 🔸 Reconstruction: This was not a routine refit. Virtually every major combat system, sensor, electronic suite and cable network was replaced, while much of the internal machinery was renewed. 🔸 Strategic role: Admiral Nakhimov can serve as the protected command and strike centre of a naval formation. Its endurance, layered defenses and hypersonic weapons would force NATO fleets to track a heavily armed mobile missile base across Russia’s northern maritime approaches. The project took far longer and cost far more than planned, but Russia is now close to recovering a concentration of surface firepower that no Western navy currently fields on a single non-carrier warship. Does NATO have an effective answer to a Zircon-armed nuclear cruiser?

NewRulesGeopolitics

66,197 görüntüleme • 2 gün önce

🇮🇳How India Is Turning SILVER Into Money India’s 2025 Silver Bomb: The Great Remonetization The Overall Goal India is officially turning silver back into money. ✅ The Reserve Bank of India (RBI) announced a landmark policy: starting April 1, 2026, banks can accept silver as loan collateral. ➡️ This "remonetizes" silver for the first time in modern history. The Key Policy: Banking Collateral 🔸A unified framework for loans against precious metals. 🔸Eligible collateral: Silver jewelry and coins (up to 10 kg per borrower). 🔸Loan-to-Value ratios up to 85% for smaller loans. 🔸Full borrower protections: collateral returned within 7 days of repayment. The Two-Layer Strategy Layer 1: Financial Inclusion ✅ Unlocks ~10,000–15,000 tonnes of household silver (mostly jewelry). 💰 Provides quick, low-interest loans to rural and middle-class families. ➡️ Expected impact: ₹50,000–100,000 crore in new lending by 2027. Layer 2: Strategic Reserves 🏛️ Banks collect pledged silver → creates de facto national stockpiles. 🌍 Aligns with BRICS de-dollarization efforts. ⚡ Complements booming industrial demand (AI, EVs, solar). The Numbers (Nov 2025) ✅ Household Silver: ~10,000–15,000 tonnes ✅ Annual Demand: ~3,500–4,000 tonnes (25-30% of global total) ✅ Silver Price: ₹1.9 lakh/kg (lifetime highs, up 40% YTD) ✅ Gold-Silver Ratio: ~80:1 (historical buy signal) Why This Is Genius 🔸 Unlocks "dead capital" for 100M+ households. 🛡️ Builds sanctions-proof reserves. 🌐 Sets global precedent for BRICS nations. 📈 Massive bullish implications for silver prices. ➡️Paves the way for silver as collateral for other monetary instruments India has triggered a monetary revolution by turning household silver into bank collateral, unlocking trillions in hidden wealth while positioning silver as a strategic asset in the new BRICS-led financial system. #Silver #India #BRICS #MonetaryPolicy #Investing #Commodities #RBI

Mark

46,489 görüntüleme • 9 ay önce

Japan Will Have to Rely on Its revolutionary Lithium Submarines Against China’s New Type 95 Nuclear Submarine China is expected to commission its first Type 95 nuclear-powered attack submarine in the coming weeks, a 7,000-8,000t vessel whose details remain largely estimates. By steadily refining Russian-derived technology, the Chinese are seeking to approach the performance level of the U.S. Virginia class. The Type 95 features modern technologies such as a pump-jet propulsor, advanced sensors, and numerous improvements over the earlier Type 093B. It is believed to achieve sustained speeds of around +25 knots. On the Japanese side stands the revolutionary Taigei class: diesel-electric submarines equipped with lithium-ion batteries that can remain submerged for up to three weeks and recharge in just a few hours. The latest units have incorporated upgrades including quieter snorkel systems, enhanced sensors, and improved battery performance. Can the 3,000-ton Taigei submarines deter the Type 095, which displaces more than twice as much? Both the Sea of Japan and the East/South China Seas feature extensive deep-water areas that strongly favor a nuclear submarine’s ability to maintain high constant speeds. Yet the Taigei would not be easy prey: its high-speed sprints nearly match the Chinese submarine’s cruising speed. Multiple Taigei boats would likely attempt to ambush a Type 95 if it ventured into shallower waters near Japan. Japanese electric submarines remain extremely quiet even at speeds above 10 knots for several days, setting the stage for a true underwater hunt. The Type 95 is expected to introduce new Chinese technologies specifically aimed at detecting very quiet submarines. In the coming years, the Type 95 fleet will gradually grow, but it will eventually face the Taigei’s successor, expected to feature solid-state batteries, higher speeds, submerged endurance approaching 60 days, and recharging times measured in minutes. Anticipating this, China is investing in the Type 041, which reportedly incorporates a compact micro-nuclear reactor and Lithium batteries, offering characteristics similar to the advanced Japanese submarines but with unlimited submerged endurance and greater speed. This is a head-to-head technological race between two major powers.

Patricia Marins

21,575 görüntüleme • 6 ay önce

🚨🚨🇮🇷🇺🇸 BREAKING | If this is confirmed, we can say that the US has lost the war with Iran. The Iranian news agency Mehr, citing the Iranian Ministry of Foreign Affairs, has published all 14 clauses of the Memorandum of Understanding (MoU) signed with the US: 1. Permanent and immediate cessation of war on all fronts, including Lebanon. 2. The US commitment to non-interference in Iran's internal affairs and respect for the sovereignty of the Islamic Republic of Iran. 3. Complete lifting of the naval blockade within 30 days. 4. The US commitment to withdraw its forces from around Iran. 5. Reopening of the Strait of Hormuz within 30 days under Iranian arrangements. 6. Suspension of sanctions on the sale of oil, petrochemical products, and derivatives, and full access of Iran to its financial resources. 7. The necessity for the US and its allies to present reconstruction plans for Iran amounting to at least 300 billion dollars. 8. 60 days of negotiations to reach a final agreement based on nuclear issues and the complete lifting of primary, secondary, US sanctions, and UN Security Council and IAEA Board of Governors resolutions. 9. Reiteration of Iran's commitment under the NPT treaty not to produce nuclear weapons. 10. During the negotiation period, the US has committed not to add forces in the region and not to impose new sanctions. 11. Release of 24 billion dollars of Iran's blocked funds during the 60-day final negotiation period. Half of this amount must be made available to Iran before the start of negotiations. 12. Formation of a supervisory mechanism to implement the agreement. 13. The final agreement will be approved by a UN Security Council resolution. 14. Final negotiations will not begin before the release of half of Iran's blocked funds, suspension of Iran's oil sanctions, and lifting of the naval blockade, and the final agreement will only cover the fate of enriched materials and enrichment, lifting of sanctions, and Iran's economic reconstruction plan. Discussions about Iran's missile program and support for resistance groups are definitively removed from the agenda. As a reminder, the official signing of the memorandum is scheduled for June 19 in Geneva. See the latest updates with us: Visioner

Visioner

477,048 görüntüleme • 2 ay önce

Russia has successfully launched an Russia has successfully launched an RS-24 Yars intercontinental ballistic missile (ICBM) from the Plesetsk Cosmodrome. The Russian Defense Ministry said the launch was conducted to verify the missile system’s tactical, technical, and flight characteristics. Training warheads reached their designated impact area. intercontinental ballistic missile (ICBM) from the Plesetsk Cosmodrome. The Russian Defense Ministry said the launch was conducted to verify the missile system’s tactical, technical, and flight characteristics. Training warheads reached their designated impact area. Facts Russian/NATO DesignationSS-27 Mod 2/ RS-24 Yars VariantsNo Variants Mobility and RoleRoad-mobile/Silo-based ICBM Designer/ProducerMoscow Institute of Thermal Technology Range10,500-12,000 k Warhead Type and WeightNuclear/ 49,600 kg MIRV and YieldMIRVx10 /250-300 kt Guidance System/AccuracyInertial with Glonass Stages/Propellant3 stages/ Solid-Fueled IOC/Retirement2010/Still Active Status/Number of UnitsOperational/63 mobile;10 silo-based Launch Vehicles Compatible with older Russian Silos Yars TEL/MZKT-79221 Development The RS-24 Yars intercontinental ballistic missile is a MIRVed version of the Topol-M with the payload modified to carry up to 10 MIRVs each containing a thermonuclear warhead weighing 300 kilotons. The Yars is 3 staged, solid-fueled and can be launched from a silo or mobile launcher. Like its predecessor the Topol-M, the Yars is designed to evade missile defense systems and is becoming a foundational part of the Russian Strategic Missile Forces (RSMF) with an estimated 80% of Russia’s ground-based missile force being made up of Topol-M and Yars missiles by 2016. Since its introduction in 2010, when the first road-mobile Yars was deployed at Teykovo, the Yars has replaced SS-19 missiles at the 28th Missile Guards Division at Kozelsk, and is deployed at Novosibirsk and Tagil. Russia also continues to retire old SS-18, SS-19, and SS-25 missiles replacing them with the Yars or deactivating silos and garrisons. Strategic Implications The RS-24 Yars has been at the forefront of Russian efforts to modernize its nuclear forces. The Yars gives the ground based element of Russia’s Nuclear Triad increased effectiveness through its ability to evade missile defense systems. The missile has the capability to maneuver during flight and deploy both active and passive decoys which gives Yars the advantage against modern missile defense systems. The RS-24 is Road-mobile and can deploy in retired Russian missile silos making the missile more difficult to detect. This coupled with the fact that the Yars only takes 7 minutes to launch poses serious threats to the missile defense system used by the US to protect its homeland and its allies. The RS-24 is a vital part of Moscow’s effort to increase the survivability its nuclear forces and to counter missile defense systems being deployed by the United States. The Yars ICBM is expected to stay a vital part of Russia’s Nuclear Forces for the next 20 years.

Ignorance, the root and stem of all evil

17,733 görüntüleme • 5 gün önce

Demis Hassabis, the Nobel Prize winner who runs Google DeepMind just described the most consequential project on earth, and most people have no idea it exists. The project is called Isomorphic Labs and the goal is to end the way drugs have been developed for the last century. Here is the problem it is trying to solve. Developing a single drug today takes an average of 10 years, costs billions of dollars, and fails 90 percent of the time before it ever reaches a patient. Of every 10 drugs that enter clinical trials, only one makes it through. The other nine years of work, the other billions of dollars, the other scientific careers, gone. Hassabis believes AI can collapse that entire process from identifying a disease target to designing a compound that binds to it, predicts how it behaves in the body, and minimizes side effects , end to end, on a computer, before a single experiment is run. The foundation is AlphaFold, the AI system that solved one of biology's hardest problems predicting the 3D structure of every protein in the human body and won him the Nobel Prize in Chemistry in 2024. But knowing a protein's shape is only one part of designing a drug. Isomorphic is building what Hassabis describes as adjacent systems , AlphaFold 3, AlphaFold 4, and now a unified model called IsoDDE , that take the next steps. From designing the actual chemical compound that binds to the protein, predicting its binding strength, identifying new pockets to target that no one has ever found before. IsoDDE more than doubles the accuracy of AlphaFold 3 on the hardest protein-ligand prediction benchmarks that exist. Isomorphic is already running 18 to 19 live drug programs, cardiovascular disease, cancer, immunology in partnership with Eli Lilly, Novartis, and Johnson and Johnson. The first human clinical trial of a fully AI-designed drug is expected by the end of 2026. If that trial succeeds, it will be the first time in history that a drug put into a human body was designed not by a team of chemists working for a decade but by an AI working for months. Hassabis's long-term vision is even more direct, one day you describe a disease, click a button, and a drug blueprint comes out the other side. AI will solve almost all diseases within 10 years.

Milk Road AI

36,062 görüntüleme • 4 ay önce

There’s a common perception in Kashmir that medicines sold in the market are not genuine — which is not true! The idea of “nakli dawai” is mostly a myth! A medcine can be substandard but not NAKLI ! However! Concerns do exist about substandard medicines allegedly being sold by certain private nursing homes and clinics! These are often procured through contract manufacturing units in places like Baddi and parts of Gujarat! And the biggest problem is that such medicines are often available only at the drug counters of those specific clinics or nursing homes, not in the open market or reputed pharmacies! This makes it very difficult for patients who need to continue the same medication, as they are forced to travel all the way back to that particular place just to buy it again! Medicines are generally manufactured and sold under two categories: ethical and generic! Ethical drugs are usually prescribed by doctors and follow regulated pricing structures, usually allowing a margin of 15–20%.! Generic medicines on the other hand are sold directly and can have profit margins as high as 80%.! This is where the confusion begins! Consumers assume that all medicines carry such high margins — which is not the case! People often ask how some chemists offer huge discounts! The answer lies in the model! Many of these outlets are charity driven or not for profit setups where profit isn’t a concern! Some private chemists also offer steep discounts without properly calculating their overheads — but eventually most of them are unable to sustain and end up shutting shop! Another false notion often heard in Kashmir is that Mr. X sells genuine medicines while Mr. Y doesn’t! How is that even possible when the company is the same, the C&F agent is the same and the distributor delivering to both is also the same .. Are we saying the distributor is sending genuine stock to one and fake to the other .. That’s simply not possible—unless the stock is being procured from some other place or source! For consumers there’s a simple way to verify the authenticity of a medicine! Standard medicines, especially those manufactured by multinational companies carry barcodes and embossed codes on the strips! You can scan the code or send it directly to the manufacturer to authenticate its genuineness — and receive confirmation within seconds! Moreover! J&K has a state of the art drug testing laboratory in Kathua — one of its kind in North India — where the Drug Control Department regularly sends samples for testing and issues detailed reports on their quality and authenticity! Let’s not generalise or spread panic! The Drug Enforcement Agency in J&K is among one of the strongest in the country, with a robust regulatory framework! Sampling and analysis are conducted regularly! While isolated cases may occur, the medicines sold in Kashmir are largely genuine and safe!

Tahir Peerzada

22,310 görüntüleme • 1 yıl önce