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The most radically recoded genome yet! Syn57 is E Coli with only 57 codons, freeing space to encode up to 4 non-canonical amino acids. That, combined with its virus resistance, will make it an incredible tool for biomanufacturing. From the Chin Lab in Science Magazine

Julia Bauman

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30,168 views • 11 months ago •via X (Twitter)

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If you haven’t heard it yet, check out the latest episode of the pod that dropped this week! We learn about novel method to access non-canonical amino acids and peptides via cross-electrophile coupling in collab with MP Watson Lab! #MerckChemistry

If you haven’t heard it yet, check out the latest episode of the pod that dropped this week! We learn about novel method to access non-canonical amino acids and peptides via cross-electrophile coupling in collab with MP Watson Lab! #MerckChemistry

Pharm to Table Podcast

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Iran will never turn its back on the resistance It will share the bread from its own table to assist its allies. There is nothing in the deal Trump signed in Versailles that requires Iran to sever its relations with the Axis of Resistance Follow #MOATS 564 #georgegalloway #Iran #Trump #Versailles #AxisofResistance

Iran will never turn its back on the resistance It will share the bread from its own table to assist its allies. There is nothing in the deal Trump signed in Versailles that requires Iran to sever its relations with the Axis of Resistance Follow #MOATS 564 #georgegalloway #Iran #Trump #Versailles #AxisofResistance

George Galloway

12,198 views • 1 month ago

‼️ 323 vials containing deadly viruses go missing from a lab in Australia — ABC News Among them, nearly 100 vials contained the Hendra virus (transmitted from horses to humans, with a 57% fatality rate). Two vials contained the hantavirus (spread by rodents, with a 38% fatality rate), and 223 vials contained the lyssavirus (rabies virus, with an almost 100% fatality rate). The most likely cause of the "disappearance" is thought to be the loss of containers during transfer to a new freezer. The Ministry of Health is conducting an investigation.

‼️ 323 vials containing deadly viruses go missing from a lab in Australia — ABC News Among them, nearly 100 vials contained the Hendra virus (transmitted from horses to humans, with a 57% fatality rate). Two vials contained the hantavirus (spread by rodents, with a 38% fatality rate), and 223 vials contained the lyssavirus (rabies virus, with an almost 100% fatality rate). The most likely cause of the "disappearance" is thought to be the loss of containers during transfer to a new freezer. The Ministry of Health is conducting an investigation.

NEXTA

5,733,651 views • 1 year ago

Cara is back in Leinster House today for the thousands of children being failed by this government. Children are legally entitled to an assessment of needs within 6 months, yet the government continues to break the law, with devastating consequences. The government must act and the Combined Opposition will continue to work with Cara to make it happen.

Cara is back in Leinster House today for the thousands of children being failed by this government. Children are legally entitled to an assessment of needs within 6 months, yet the government continues to break the law, with devastating consequences. The government must act and the Combined Opposition will continue to work with Cara to make it happen.

Mary Lou McDonald

15,517 views • 11 months ago

Muscle loss with age is common, but much of that decline is driven by inactivity, not aging alone. On average, we reach peak muscle mass somewhere between 20 and 30, then lose about 8% per decade after that. By the time many adults reach their 70s and 80s, they may have only 60–80% of the muscle mass they had at 30. A big reason why is anabolic resistance. As we get older, muscle becomes less responsive to amino acids, one of the key signals for building and maintaining muscle. This is where resistance training becomes non-negotiable. It's one of the main signals that tells muscle to grow. And just as importantly, it helps re-sensitize muscle to amino acids, so the body responds to protein more like it did when you were younger.

Muscle loss with age is common, but much of that decline is driven by inactivity, not aging alone. On average, we reach peak muscle mass somewhere between 20 and 30, then lose about 8% per decade after that. By the time many adults reach their 70s and 80s, they may have only 60–80% of the muscle mass they had at 30. A big reason why is anabolic resistance. As we get older, muscle becomes less responsive to amino acids, one of the key signals for building and maintaining muscle. This is where resistance training becomes non-negotiable. It's one of the main signals that tells muscle to grow. And just as importantly, it helps re-sensitize muscle to amino acids, so the body responds to protein more like it did when you were younger.

Dr. Rhonda Patrick

261,721 views • 3 months ago

$HIMS THE PEPTIDE SUPPLY CHAIN --- JUST 5 COMPANIES IN CHINA CONTROL ~90% OF THE AMINO ACIDS 🤯 Mansi: "Before any peptide is produced, you need its API, which stands for 'active pharmaceutical ingredient', and right now China supplies most of the world's API" "The top 5 companies in China control around 90% of the protected amino acids, which is essentially the raw building block of a peptide." "You can't attach raw amino acids to each other. That's a very volatile and chaotic process... The error rate tends to compound every time you attach one amino acid to the other. So for example, BPC-157 sits at around 15 amino acids, and it tends to come out correct around 75% of the time. And Semaglutide (Ozempic) sits at 31 amino acids, and that comes out correct around 50% of the time." "This is why China wins: because they have this at massive scale to compensate for these efficiency issues." "CordenPharma in Colorado is the largest in the US. They have around 10,000 liter of SPPS reactor capacity." "But in China there's a company called WuXi AppTec, which has 100,000 liters of capacity... more than 10x larger than *the largest* synthesis plant here in the United States."

$HIMS THE PEPTIDE SUPPLY CHAIN --- JUST 5 COMPANIES IN CHINA CONTROL ~90% OF THE AMINO ACIDS 🤯 Mansi: "Before any peptide is produced, you need its API, which stands for 'active pharmaceutical ingredient', and right now China supplies most of the world's API" "The top 5 companies in China control around 90% of the protected amino acids, which is essentially the raw building block of a peptide." "You can't attach raw amino acids to each other. That's a very volatile and chaotic process... The error rate tends to compound every time you attach one amino acid to the other. So for example, BPC-157 sits at around 15 amino acids, and it tends to come out correct around 75% of the time. And Semaglutide (Ozempic) sits at 31 amino acids, and that comes out correct around 50% of the time." "This is why China wins: because they have this at massive scale to compensate for these efficiency issues." "CordenPharma in Colorado is the largest in the US. They have around 10,000 liter of SPPS reactor capacity." "But in China there's a company called WuXi AppTec, which has 100,000 liters of capacity... more than 10x larger than the largest synthesis plant here in the United States."

Hims House

222,322 views • 3 months ago

David Friedberg: “This will be one of the most amazing discoveries of our lifetime” “Friedberg, what's your Breakthrough of the Year?” “Okay, we haven't talked about it on the show, this definitely deserves a science corner, but asteroid Bennu.” “NASA sent a probe. They pulled a bunch of samples up in 2020. They landed back on Earth in 2023.” “Two days ago, they showed that on asteroid Bennu, there are nucleic acids, there are amino acids, there are sugars.” “All of the building blocks of life were found on this asteroid floating through space.” “This is going to end up being one of the most amazing discoveries of our lifetime because it really does show that life is not necessarily unique to planet Earth.” “This was an asteroid that's been floating around for 4.5 billion years, and it's got all the components of life on it.” “It's a pretty incredible discovery.” ------------------------------------ Thanks to our partners for making this happen! Google Cloud:

David Friedberg: “This will be one of the most amazing discoveries of our lifetime” “Friedberg, what's your Breakthrough of the Year?” “Okay, we haven't talked about it on the show, this definitely deserves a science corner, but asteroid Bennu.” “NASA sent a probe. They pulled a bunch of samples up in 2020. They landed back on Earth in 2023.” “Two days ago, they showed that on asteroid Bennu, there are nucleic acids, there are amino acids, there are sugars.” “All of the building blocks of life were found on this asteroid floating through space.” “This is going to end up being one of the most amazing discoveries of our lifetime because it really does show that life is not necessarily unique to planet Earth.” “This was an asteroid that's been floating around for 4.5 billion years, and it's got all the components of life on it.” “It's a pretty incredible discovery.” ------------------------------------ Thanks to our partners for making this happen! Google Cloud:

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177,774 views • 6 months ago

Rob Powell on Labours most vulnerable seats to a challenge from the left Lab will be pleased with his conclusion - "the big question for left wingers, will they still vote against Lab if it means letting in Reform" (its the framing they'll be using come election time)

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High-dose omega-3s (4-5g/day) can blunt the disuse atrophy that occurs with age by upwards of 50% This occurs because omega-3s sensitize skeletal muscle to amino acids In other words, when it comes to protein, you get more bang for your buck

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FoundMyFitness Clips

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Krea real-time editing is so cool..! Great job team Krea. Love that you continue to push for these real-time workflows WITH control ❤️ Here, I've combined it with my favorite 3d sculpting tool, Dreams (someone should pick this up and continue the incredible work Media Molecule started), and a bit of point-cloud magic with Apple sharp and Octane render. Share this if you agree its incredible, or heck, share it and make fun of me for continuing to think workflows like this is the future if you don't agree :P

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Martin Nebelong

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“Cuba’s president has said that attempts to take the island will be met with ‘impregnable resistance’. "That resistance is now international.” Novara Media’s Steven Methven is in Cuba, reporting on a convoy delivering aid to Cubans struggling under Trump’s oil embargo. More than 4 tonnes of supplies have now been flown to Cuba from Italy, with more on its way from Mexico.

Novara Media

73,002 views • 4 months ago

An ONLF fighter in the Ogaden Somali region with a lion cub that lived among the resistance. The fighter nurtured this cub for 4 months as it followed him from battle to battle. [Archive]

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OgadenSoldier ⛩

163,051 views • 8 months ago

Here is the email trail I reported on in 2020 showing what The White House is now admitting, that Fauci and collaborators acted to cover up the lab origin of #covid. It all started with an email to Fauci saying that some of the features of the virus look engineered. A thread...🧵

Here is the email trail I reported on in 2020 showing what The White House is now admitting, that Fauci and collaborators acted to cover up the lab origin of #covid. It all started with an email to Fauci saying that some of the features of the virus look engineered. A thread...🧵

Chris Martenson

14,516 views • 1 year ago

$RKLB The newly confirmed NASA Chief, Jared Isaacman, mentioned Rocket Lab twice today on Bloomberg: "We're grateful for those that go in commercial industry, whether it's, again, Blue Origin, SpaceX, Rocket Lab" "It is an incredible field of commercial space companies that exist today. I mean, you can talk about Stoke and ULA and Rocket Lab and Firefly." I think it's fair to say Isaacman is set to usher in a new era for commercial space companies and I believe Rocket Lab is best positioned to benefit from it.

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ValueOverPrice

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In an interview for #AlMayadeen, Professor Mohammad Marandi clarified that the #UnitedStates "is being utterly ignorant in its confrontation with the Islamic Republic of Iran and the axis of resistance." He explained that #Iran and the Axis of Resistance have not yet begun escalation and did not initiate the war, but have been trying to prevent the region from being destroyed. Gulf states in the region, Marandi says, miscalculated by underestimating the Axis of Resistance and overestimating the #US, and warned them that their only solution is to back down and force the United States to leave. #IranWar #WestAsia Seyed Mohammad Marandi

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Al Mayadeen English

41,007 views • 4 months ago

An illegal bio lab was just raided in Vegas. It is directly linked to the secret Chinese lab found in California in 2023, which was oozing with E. Coli, HIV, and Malaria. Congress must pass our bill to find these illegal labs and shut them all down.

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Rep. Kevin Kiley

539,568 views • 6 months ago

Love is in the air, and it blooms in the night. So light it up with #GalaxyS25Ultra that offers an unrivaled Nightography experience to capture the most detailed shots even in low light, and make the most of your special moments.

Love is in the air, and it blooms in the night. So light it up with #GalaxyS25Ultra that offers an unrivaled Nightography experience to capture the most detailed shots even in low light, and make the most of your special moments.

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With Zack Martin retiring … Here’s a cut up from the 2019 season showing all the explosive run and screen plays behind number 70 An incredible player with pinpoint technique and power with the ability to dominate in space that set him apart

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It’s incredible that we can treat sickle cell disease with CRISPR, but it’d be extremely useful to have a pill that does the same thing. Work from Pamela Ting Jay Bradner, M.D. in Science Magazine show it may be possible with a molecular glue small molecule!

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