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This 15 minute video will solve all your doubts about creatine monohydrate. Instant bookmark.

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Dr. Anshul Sadhale

21,041 subscribers

13,363 Aufrufe • vor 5 Monaten •via X (Twitter)

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Creatine monohydrate has been the king for decades. Every few years some company tries to reinvent it with a flashy name and a bigger price tag and every time it turns out to be hype. The studies were done on monohydrate. The results were built on monohydrate. It works. Period. But here’s the real question. If monohydrate is the gold standard, can you make the gold even purer? That’s what nnbnutrition set out to do with PUREST Creatine. Not a new “form.” Not a gimmick. Just creatine monohydrate taken to another level of purity. The cleanest assay I’ve personally seen on a creatine raw material. Just the ingredient that actually builds strength, power, and muscle, produced to a higher standard.
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Creatine is for Brain Power, not Just Muscle Power A New RCT just dropped looking at creatine hydrochloride (HCl) and creatine ethyl ester (CEE) on cognitive outcomes (PMID: 40854087). Researchers gave perimenopausal women 8 weeks of either low-dose creatine HCl (750 mg or 1.5 g / day), a blend of HCl + CEE, or placebo. 👉 The 1.5 g HCl group showed small but significant improvements in reaction time and even a ~16% increase in frontal brain creatine levels on MRS scans. The HCl + CEE combo didn’t outperform HCl alone. All forms were well-tolerated and there were no serious side effects. The results add to growing evidence that creatine supports cognition—not just strength, hypertrophy, and power—but let’s keep perspective: ⚠️ Creatine ethyl ester has consistently underperformed in bioavailability studies. Multiple head-to-head trials show it’s rapidly degraded to creatinine in the gut and fails to meaningfully raise muscle creatine compared to creatine monohydrate (PMID:19228401). Creatine HCl seems to dissolve better in water and some anecdotal reports claim it’s easier on digestion for some people, but so far there’s no solid evidence it improves muscle or brain creatine stores beyond what you get with monohydrate. Bottom line: this study is promising for the cognitive benefits of creatine overall, but it doesn’t change the main recommendation Creatine monohydrate is still the gold standard. It’s the form used in hundreds of human RCTs, proven to raise muscle and brain creatine, and it’s cheap. Until stronger data show otherwise, save your money and stick with monohydrate.
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