Loading video...

Video Failed to Load

Go Home

#TIPS_&_Tricks for ostial RCA disease with tortuous vessel NSTEMI scenario here .. What happened ?? #TROUBLESHOOTING - AVOID AMPLATZ guides - Airmailing technique to be used with a soft torquable wire & preferably with trackable microcatheter - DO NOT INJECT when this has happened, if u have to use...

11,916 views • 1 year ago •via X (Twitter)

10 Comments

Dr . $@ndeep K@m@t's profile picture
Dr . $@ndeep K@m@t1 year ago

I would shift to femoral and I prefer doing something called "Amplazting" of a JR guide catheter(looping the JR guide) like this in such scenarios..always works fr me especially when the RCA ostium is nasty.

Abad khan,MD/DM's profile picture
Abad khan,MD/DM1 year ago

But AMPLATZING of JR will cause the same issue and runs the same risk of ostial Dissection of a dominant RCA ..

Joy Sanyal,MD, DM,'s profile picture
Joy Sanyal,MD, DM,1 year ago

Probably a XB RCA or a 7F JR with GEC- usually I always do it with XB RCA instead of AL it has shorter curve

Abad khan,MD/DM's profile picture
Abad khan,MD/DM1 year ago

Great options .. But GEC ? For dominant RCA's and Ostial and proximal diseases is it the best option to use GEC to reach distal RCA if hardware doesn't track in a tortuous anatomy ?

SREEVATSA NADIG DM FSCAI FESC's profile picture
SREEVATSA NADIG DM FSCAI FESC1 year ago

Ostial RCA dissected and vessel closed

Abad khan,MD/DM's profile picture
Abad khan,MD/DM1 year ago

No no no .. There is a very peculiar thing happening which was stored on this florosave loop which almost RULES OUT DISSECTION WITH ABRUPT VESSEL CLOSURE ..

Sudeep K N's profile picture
Sudeep K N1 year ago

Suspicious prox dissection while pulling back diagnostic catheter .can see dye stasis in upper portion of RCA..... interesting to know how case was managed.

Abad khan,MD/DM's profile picture
Abad khan,MD/DM1 year ago

No dissection .. but u risk one when such thing has happened and u give dye injection

hitesh's profile picture
hitesh1 year ago

Amplatz confirmed the ostial disease

Qasim Raza, 𝘔𝘋's profile picture
Qasim Raza, 𝘔𝘋1 year ago

It's like Carabellos sign but for coronaries 😄 for those curious:

Related Videos

Sachs, apparently before he lost his mind, during his visit to Ukraine after Maidan (which he now claims is when he learned how the CIA staged it), on April 17 2014: “I’m no expert on Ukraine by any means… Ukraine’s economic growth had already basically run out of steam in recent years and the quality of governance was very bad with massive corruption and lack of vision about transformation. The crisis that is really very very serious that Russia has really provoked in recent weeks, with the economy so intertwined with Russia, the various hostile actions by Russia are profoundly challenging for this country, obviously, not only militarily but also economically. … If it happens that Russia remains antagonistic and aggressive to this country — really closing trade, provoking crises — that would have serious economic effects. … If Russia pursues this course, which is a very dangerous one, it will have massive economic implications for Russia. … Of course that’s the same for Ukraine or for others that the only way to upgrade industry adequately here, to really raise living standards, would be much closer integration of production here, and in Europe, with China, with other parts of the world. And now Russia seems to be putting its geopolitics in front and cause what it would seem to be a very, very serious economic setback for it if it pursues this line. So the line that it’s been pursuing with Crimea and, right now, with the troop buildup and so forth, is a very dangerous for the Russian economy.” What the hell happened to this guy?

Branislav Slantchev

160,770 views • 10 months ago

LDL Cholesterol Saves Lives! What a fantastic example of cherry picking! Yes this person is right, in ELDERLY people, all cause mortality is greater amongst those with low LDL cholesterol… but WHY? And why didn’t he bring up all cause mortality with LDL levels amongst those who are not elderly? Oh because he doesn’t like that data. This is a textbook example of reverse causality. LDL Cholesterol is not protecting people from disease, but rather people with wasting diseases like cancer are more likely to be resistant to wasting if LDL is not low, indicating that they are not emaciated. But if we zoom out of the elderly and look at lifelong LDL exposure & the risk of mortality, it tells a very different story. Lifelong LDL cholesterol exposure has a LINEAR association with increased mortality, especially from cardiovascular disease (CVD) (PMIDs: 23083789, 38241044, & 30694319). In fact, reduced LDL exposure early in life throughout adulthood can reduce the chance of mortality from CVD by up to 3 times! Gee I wonder why he didn’t mention that. Additionally, the unremarkable results from many statin trials comes from the fact that often these are prescribed after a CVD event or later in life when someone has already done significant damage to their blood vessels. But even with that being the case we do see a clinically significant benefit in lowering the risk of mortality with statin use (PMIDs: 36233511 & 37368941). That said, statins can have some side effects & are not appropriate for everyone & you should speak to a cardiologist about your options if you have high LDL But this is a textbook example of carnivore zealots trying to do f***ery with science & giving you a 3rd of the info to try to trick you into believing their nonsense

Layne Norton, PhD

89,928 views • 1 year ago

Jensen Huang: "People with really high expectations have very low resilience." "I think one of my great advantages is that I have very low expectations. And I mean that. Most of the Stanford graduates have very high expectations. And you deserve to have high expectations because you came from a great school. You were very successful. You're top of your class. Obviously, you were able to pay for tuition. And then you're graduating from one of the finest institutions on the planet. You're surrounded by other kids that are just incredible. You naturally have very high expectations. People with very high expectations have very low resilience. And unfortunately, resilience matters in success. I don't know how to teach it to you except for I hope suffering happens to you. And I was fortunate that I grew up with my parents providing a condition for us to be successful on the one hand, but there were plenty of opportunities for setbacks and suffering. And to this day, I use the phrase pain and suffering inside our company with great glee. And I mean that. Boy, this is going to cause a lot of pain and suffering. And I mean that in a happy way, because you want to train, you want to refine the character of your company. You want greatness out of them. And greatness is not intelligence. Greatness comes from character, and character isn't formed out of smart people. It's formed out of people who suffered. And so if I could wish upon you, I don't know how to do it. For all of you Stanford students, I wish upon you ample doses of pain and suffering."

Founder Mode

1,088,772 views • 6 months ago

Sorry for the lack of spaces / activity folks 😞 Unfortunately, my wife has been dealing with some very painful stomach issues. This has required us to go to the emergency room twice now, a GI, other doctors, and a slew of tests. So far they are still not sure what is wrong with her health. The medical costs have piled up once again (seems we have been cursed for the past year), and its getting extremely tough. To pay for all these medical procedures and doctors, we might not be able to make rent this month.. this causes further stress, which just exacerbates the entire thing. I don't like to beg for for help without giving anything back. Instead, if you'd like to help, please consider buying a Crypto Mechas NFT / Card collectible. This way, you can help if you want AND get a Physical Card + NFT for your money. For the next 48H ⏰, all NFTs and cards are 20% OFF on the Crypto Mechas website. You can use the following coupon code at checkout: MOONWIFE20 You can get your cards on the website below, or you can DM me for details. You can also get a Custom NFT + Card with your picture or your pet picture or anything really, if you'd like one. DM me in this case. (Name, address and email required for shipping) I am sorry for coming back to you guys with this again. Last thing I want is to bother any of you with this bull.. It's been a tough year for us 😅 Thank you all so much. #EGCfam is still the best community in Defi, and will always be. I will return to making spaces as soon as possible 🙏 #EGC #evergrow
0:20

Sensitive content

Sorry for the lack of spaces / activity folks 😞 Unfortunately, my wife has been dealing with some very painful stomach issues. This has required us to go to the emergency room twice now, a GI, other doctors, and a slew of tests. So far they are still not sure what is wrong with her health. The medical costs have piled up once again (seems we have been cursed for the past year), and its getting extremely tough. To pay for all these medical procedures and doctors, we might not be able to make rent this month.. this causes further stress, which just exacerbates the entire thing. I don't like to beg for for help without giving anything back. Instead, if you'd like to help, please consider buying a Crypto Mechas NFT / Card collectible. This way, you can help if you want AND get a Physical Card + NFT for your money. For the next 48H ⏰, all NFTs and cards are 20% OFF on the Crypto Mechas website. You can use the following coupon code at checkout: MOONWIFE20 You can get your cards on the website below, or you can DM me for details. You can also get a Custom NFT + Card with your picture or your pet picture or anything really, if you'd like one. DM me in this case. (Name, address and email required for shipping) I am sorry for coming back to you guys with this again. Last thing I want is to bother any of you with this bull.. It's been a tough year for us 😅 Thank you all so much. #EGCfam is still the best community in Defi, and will always be. I will return to making spaces as soon as possible 🙏 #EGC #evergrow

MoonAndroid 🌕

11,076 views • 2 years ago

Positioning of drugs in Crohn's disease ___ 1. Start effective therapy early This means at diagnosis in the vast majority of patients. Don’t make patients earn their way onto an effective drug. And use your best drug first. Please do not “save it in case you need it later”. ___ 2. Which of our effective therapies should you start? This matters less that just starting. Think holistically with a patient-centered approach. Age, co-morbidities, extra-intestinal manifestations, pregnancy, etc all important. Consider efficacy - speed of onset, mucosal healing, durability of remission - and safety. Mode of delivery - intravenous, subcutaneous, oral - is important. But comes after patient factors, efficacy and safety. Access issues will predominate for many. Use what you have. Use what you know. Just use an effective drug. ___ 3. Use a treat-to-target approach Without labouring the points around STRIDE-2, I’ll put it very simply: - monitor, monitor, monitor act on the results of the monitoring. Don’t keep going with a therapy that isn’t working. ___ 4. Know when to dose optimise versus switch Optimising anti-TNF is often a good ploy. But do it properly and don’t wait too long. Double the dose, shorten the frequency and wait 2-3 cycles. If it isn’t working then (objectively), switch out of class. With ustekinumab, I would no longer dose optimise, but rather switch a partial responder to risankizumab. ___ 5. Active disease is more dangerous than any drugs Two bits of data this year show this: i) In Profile, patients in the step-up group had twice as many adverse events as those in the top-down group. Most of this was because of flaring Crohn’s disease - including hospitalisations for severe disease - but there were also fewer serious infections in the top down group. And that was with combination infliximab and azathioprine. ii) Two meta-analyses of the harms from placebo in RCT’s show a very clear signal. Active Crohn’s disease and UC, when left untreated for even a number of week, is associated with increased toxicity. More on this later. ___ 6. Avoid steroids The majority of patients with Crohn’s disease can be managed effectively now without steroids. They will still have a role in sick patients, to bridge to some therapies, and a course of budesonide in mild to moderate ileal Crohn’s disease is often useful. However we have better strategies now, including using JAK inhibitors in place of steroids. We are increasingly using a short course to (re)capture response to a biologic or keeping the JAKi going in combination at a low dose. ___ 7. Other treatment modalities Surgery and nutritional therapy are particularly important. ___ 8. Changing the natural history of Crohn’s disease Disease modification is the end result when following these principles. We see it in the Edinburgh IBD clinic. A decade since we switched to a top-down strategy for Crohn’s disease and our patients have better disease control, less surgery and fewer hospitalisations. Clearly we still have work to do, but this is major progress.

Charlie Lees

15,650 views • 1 year ago

CNN’s Abby Phillip interrupts former Iranian political prisoner Kian Tajbakhsh and immediately cuts to a commercial right after he said this: “You can draw a straight line from the 2015 nuclear deal to October 7th.” TAJBAKHSH: “What happened with President Obama, I’ll just say this very quickly.” “And I was in the State Department in the 2000s when we implored the Bush administration not to restrict the engagement with Iran simply to the nuclear file.” “What happened with president Obama is that, for better or worse — and I’m not going to litigate that here — he decided that given the four big problems that have always been on American objectives with Iran, that is enrichment, ballistic missiles, proxies and democracy inside Iran, that he would put all the last three aside and focus only on the nuclear deal.” “Now, I’m not going to say that was good or bad. I don’t think it was a great idea, but what we have seen and this is also maybe controversial and I think a lot of my liberal friends are going to hate me for this…” “Is that unfortunately you can draw a straight line from the 2015 nuclear deal to October 7th.” “I think that what the Trump administration is—” PHILLIP: “We…we…we do have to go to a break here.” TAJBAKHSH: “Okay.” PHILLIP: “There’s more on the other side. So hold your thought because I have some follow up questions for you about what the endgame is here and now…”

Overton

651,427 views • 5 months ago

VIDEO | Delhi: Congress leader Manish Tewari on prominent citizens from India and Pakistan appealing PMs of both countries for 'restoring peace, normalcy, dialogue', says, "Well, that's not an appeal for a dialogue. It is an instrument of an unconditional surrender. We want peace with Pakistan, but it has to be peace without terror. It has to be peace with honour. Has Pakistan given any commitment that it will dismantle the entire military jihadi complex. That they have very assiduously nurtured since the late 1970s. Has Pakistan said that they would ensure that the soil of their country is not used for perpetrating terror against India. A commitment which was given by President Musharraf in 2002 in a televised address to the people of Pakistan, as well as reiterated when Prime Minister Atal Bihari Vajpayee visited Islamabad in December 2004 for the SAARC Summit. And then repeated ad nauseam in the conversations that took place with between Dr. Manmohan Singh and his Pakistani interlocutors, or even Prime Minister Modi later with his Pakistani interlocutors. So, therefore, the question is not peace. The question is, peace at what cost? Peace cannot come with a gun to your head, you know, with somebody holding the gun of terror to your head. And all these people who've written this letter are very eminent people in their professional and private capacities. They have dealt with the Pakistanis over the entire span of their professional careers. They exactly know as to how perfidious these people are as to how they say one thing and mean the other thing altogether. And therefore, if there has to be peace, or if there has to be a dialogue, terror and talks cannot go hand in hand. You need to ensure that Pakistan dismantles the entire infrastructure of terror that Pakistan have created. Who does not want peace? Everybody wants peace, but it has to be peace without terror and peace with honor." (Full video available on PTI Videos -

Press Trust of India

59,074 views • 1 month ago

🚨 JUST IN: Trump is at the Kennedy Center for the board meeting and a tour. He is totally overhauling it. He says they wanted to charge Lee Greenwood $30,000 just to sing there. Trump also says he is going to get with Speaker Johnson to fix its architecture. "We're here to have our first board meeting, Kennedy Center, and it's in tremendous disrepair, as is a lot of the rest of our country, most of it because of bad management." "We have a little problem with some people that work here. We had Lee Greenwood wanted to sing a little song today. And because of the cost in the union structure, for him to sing a song just for the board, just a board meeting, that was gonna cost $30,000. That doesn't sound too good. They wanted $30,000 to move a piano. So you can't have that. So we're gonna we're gonna fix it up." "It's really emblematic of our country. At the Kennedy Center, you look at the columns outside, you look at, I mean, they're supposed to be covered by something, whether it's marble or granite. They were never covered. They were painted. But, bring it into more modern times, a lot of money has been given to it, and the money has not been properly spent." "They built rooms underground with no windows, no nothing that will not be used ever. You're not gonna have people use them. It's such a waste of money, such a terrible waste, but we'll make it we'll bring it back. We'll make it great again. But it is so much like what I'm witnessing in other places." "We have open borders. We have men playing in women's sports. It's all the same thing. It's all the same mentality and thinking. So I'm very disappointed when I look around." "The bottom line, it has tremendous potential, and we'll work with Congress. As you know, it's a very public, a very public facility, and we'll do what has to be done. We'll be having a meeting with the speaker in the not too distant future. I think it's important to save this structure in this building."

Eric Daugherty

423,717 views • 1 year ago

Milestone! We (robotic arms for gadgets assembly) finished the first commercial order, which brought the first revenue. Here are some learnings from this: The customer was a smart toy manufacturer. The task was to add a heatsink to Raspberry Pi. We received parts from them and returned the assembled modules back. Currently, it's done by teleoperation. Later it will be done by a remote employee via the Internet. Then it will be automated action by action, reducing the operator's time on this and making the task profitable. ps. If you have an assembly task that we can do for you asynchronically - leave a comment below. Learning 1. It's possible! This task which is usually done by the human arm with 5 fingers can be done with a two-finger gripper with the addition of a couple of simple tooling. The task was not simplified. We peeled off thin films from stickers, unpacked paper boxes, moved PCB boards full of components, etc. And no unsolvable problems have been encountered yet. Challenges: 1) The paper box shifted during the opening Solved with the plastic walls that you can lean against 2) Heat pad, stuck to the gripper instead of heat sync. Can be solved by gripper with a pump, but this time solved with the patience of the operator 3) The film on the pad is very thin. Turned out that sub-millimeter arm precision is enough to peel it off with just a regular gripper. 4) The working area has not enough space. You'll only know this by doing real tasks in bulk. This could be solved by an extra pair of long arms, but in this case, solved with the patience of the operator. I think that in the end, we will have 5-10 types of universal tooling and 5-10 types of grippers to solve almost all the problems in such assembly tasks. Learning 2. It's slow. It took 5 times more time, than doing it with human hands. But the good news is there's a lot of room for improvement. We now have specific “time for task” metrics, which we will decrease with iterations. The main reasons for slowness: 1) To rotate the gripper to a steep angle you are forced to control one robot arm with two hands instead of using both arms. We can fix this by just making more room for rotations. 2) Grabbing PCB board with two arms is hard. A slight difference in rotation can break the board, and it's hard to control these angles visually. To solve this, the best way is to use force feedback so you can feel the pressure applied to the item. 3) Accuracy and steadiness is still can be improved We will try a metal version and double the motors to do this. 4) It is physically difficult for the human hands to move with such precision To solve this, we will add a pad for the hands like in surgical robots Learning 3. It's a good business model The "Factory in the cloud" is a good business model for this stage. You send us parts and we send back assembled modules. Currently, it's more convenient than sending a robot to your place, as we can iterate/fix the robot quickly and utilize it 100% of the time. When we polish the set-up over time - we can send robots to your place. So if we can assemble something for you in the USA with Chinese prices by using modern automation - leave a comment below.

Igor Kulakov

37,266 views • 1 year ago