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Today we're introducing TRIBE v2 (Trimodal Brain Encoder), a foundation model trained to predict how the human brain responds to almost any sight or sound. Building on our Algonauts 2025 award-winning architecture, TRIBE v2 draws on 500+ hours of fMRI recordings from 700+ people to create a digital twin...

6,941,871 просмотров • 4 месяцев назад •via X (Twitter)

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🚨Science nerds are going to lose their minds. Kai Rowan just open sourced a framework that predicts how your brain responds to any text, audio, or video by simulating cortical fMRI activity with 30% more accuracy than Meta's own model. No fMRI scanner. No neuroscience PhD. No million-dollar lab. It's called NForge. Here's what this thing actually does: → Feed it any combination of text, audio, or video and it predicts cortical surface activity across ~20,484 brain vertices → Extracts deep features via LLaMA 3.2, V-JEPA2, and Wav2Vec-BERT simultaneously → Generates ROI attention maps showing exactly which brain regions fire hardest at which moments → Runs real-time streaming predictions from live feature streams -- no pre-loading the full clip → Breaks down exactly how much text vs audio vs video drove each prediction with per-vertex modality attribution scores → Adapts to entirely new subjects with just a few calibration scans -- no full retraining required Here's the wildest part: Built on Meta's TRIBE v2 foundation but adds 6 major capabilities Meta never shipped. Cross-subject generalization. Streaming inference. Modality attribution. torch.compile support. Full test coverage. Professional src/ package layout. You literally point this at a movie clip and it tells you which parts of the human cortex light up -- broken down by what your eyes, ears, and language centers each contributed. That sentence shouldn't be real in 2026. But here we are. 100% Open Source. pip install nforge. (Link in the comments)

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244,515 просмотров • 3 месяцев назад

Mitochondria do more than power our cells: they shape how we think, feel, and experience the world. In this interview, Martin Picard breaks down his new research that illuminates how mitochondria affect brain energy, brain networks, mental health, and ultimately, our quality of life. Dr. Picard walks us through his team's revolutionary brain mapping study, which examined over 700 sections of the human brain to uncover how mitochondria are distributed and specialized by brain region and cell type. The results have profound implications for how we understand, cognitive decline, and psychiatric disorders like depression bipolar disorder and schizophrenia. In this episode, you'll learn: - Why mitochondrial health is essential for brain function - How different brain regions rely on different types of mitochondria - Why people respond so differently to the same metabolic dysfunction - How future scans and biomarkers could help us measure brain energy non-invasively - What it means to think of ourselves as “energetic beings” rather than just biological machines When it comes to metabolic psychiatry, mitochondria are a key player. This research is a huge step towards better understanding these tiny organelles and the role they play in mental health and cognitive function. Expert Featured: Dr. Martin Picard Martin Picard Resources Mentioned: Three Ways to Keep Your Mitochondria Healthy - A human brain map of mitochondrial respiratory capacity and diversity - CMEs Mentioned: Managing Major Mental Illness with Dietary Change: The New Science of Hope - Brain Energy: The Metabolic Theory of Mental Illness - Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at

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14,566 просмотров • 1 год назад