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Unfortunately some times we may lost some material inside the patient. it is better to know in advance which snares are available, how snare works, which snare for which problem and also how to make a customized snare for any different anatomy PCRonline 🫀 European Society of Cardiology #EAPCI...

15,630 görüntüleme • 1 yıl önce •via X (Twitter)

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I think that fast strides are the most powerful training stimulus for runners. For a glimpse at the physiology, I want to talk about my all-time favorite study. If we were playing FMK, I’d F this study, M this study, and K any study that is not this study. Published in 2018 in Physiological Reports, it had 20 trained athletes (14 men and 6 women) complete a 40-day intervention with 10 sessions involving 5-10 x 30 seconds with 3.5 minutes recovery, in conjunction with a 36% reduction in weekly volume. Before and after the intervention, participants did a time-to-exhaustion test, two 10km tests (one with glycogen depletion) preceded by 2 x 6 minute intervals at 60% of VO2 max, and a series of muscle biopsy and blood tests. Running economy during the 10k improved by 2.1% and during the intervals at 60% of VO2 max by 1.7%. In other words, the athletes improved at both hard efforts and easy ones. Meanwhile, there was no running economy change in the glycogen-depletion 10k, leading the authors to theorize that improvements were primarily related to changes in slow-twitch muscle fibers. Expression of protein dystrophin increased, which may enhance the ST-fiber structural integrity via the actin-myosin cross-bridge, improving running economy. In addition, the expression of UCP3 decreased, which may improve mitochondrial efficiency. In fast-twitch fibers, expression of the muscle protein SERCA1 decreased by 22%, which could reduce the energy turnover during exercise. Enzymatic activity and testosterone:cortisol ratio also went up. Don’t be discouraged, I only kinda know what a few of those words mean. The point is that as researchers introduce stride-like speed sessions and measure more variables, they often see major changes that may explain why Olympians are always doing strides. So when we use the term “running economy,” we’re actually incorporating dozens of these physiological variables, some of which we can measure and some of which we can’t, from the cells to the muscles to the circulatory and cardiovascular systems. Put it together, and getting faster is a wonderfully complex algorithm. Strides are one way to help solve it 💪

David Roche

73,596 görüntüleme • 1 yıl önce

004/100 Buttons. A bit of the process on building an animation. When looking at a finished animation or in this example a finished button, it can look quite complex inside the CSS. But when building it, it’s more like a lot of simple steps, one after another. Here I had the idea to make some kind of text animation like the footer logo on the Osmo site. I try to add the base animation with no complex easing, for example transition: translate 0.4s ease. Starting with just moving the one text from bottom to top and the other text to top. Adding a stagger, play around with it. Searching for a way to make it more circular. On the research I found the sin() function inside CSS which can build a more smooth non linear curve for the stagger which creates this circular effect. And step by step adding more complexity like, different easing for hover/hover-out, opacity, 3D transform and more. I use also the sin() function to rotate the letters, so the middle ones are getting more rotated than the outer ones. Another thing which helps is to add a small delay on hover, for example 0.05s or 0.1s, you don’t really see the difference, but when you hover pretty fast on and out it doesn’t get that jumpy. I’m using here GSAP’s SplitText to split every char into spans. And then I’m adding a CSS index variable to every span, starting from the center. SplitText can provide CSS index variables, but you cannot tell it from which direction. For the sin() it’s also important to have a max length, so I add another CSS variable with the max char number on it. Crafting 100 Buttons with Osmo ⏳ Total time: 63h

Eduard Bodak

166,023 görüntüleme • 3 ay önce