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What makes cerebral white matter more vulnerable with age? In this mouse study, we show that large and rare venules are bottlenecks for blood flow in the white matter. Deep branches of these venules are constricted with age, leading to reduced blood flow.

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Andy Shih

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33,287 görüntüleme • 2 yıl önce •via X (Twitter)

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Andy Shih profil fotoğrafı
Andy Shih2 yıl önce

An epic study by Stefan Stamenkovic and Nicolas Weiterman, with collaborators @franca_schmid (in silico modeling), Jack Waters, Kevin Takasaki from @AllenInstitute (3-photon), @HannahCBennett7 @yongsookimlab (light-sheet imaging), @stephkbeee @sosamariaj @JennyYuandongLi

Hu Lab profil fotoğrafı
Hu Lab2 yıl önce

Beautiful!

Georgia Panagiotakos profil fotoğrafı
Georgia Panagiotakos2 yıl önce

Beautiful imaging as always — looking forward to reading! Congrats Andy and team! 👏

Osama Harraz profil fotoğrafı
Osama Harraz2 yıl önce

Congratulations to you and the team! Christmas tree cerebral vessels!

Lu Liu profil fotoğrafı
Lu Liu2 yıl önce

Very cool study

Meier Lowenthal profil fotoğrafı
Meier Lowenthal2 yıl önce

inflammation constricting glymphatic clearance causing an accumulation of protein waste?

Damien Levard. profil fotoğrafı
Damien Levard.2 yıl önce

Congratulations ! Very interesting study and gorgeous 2photons images

Martin S. Matko profil fotoğrafı
Martin S. Matko2 yıl önce

Supplying Oxygen and Nutrients to every Cell blood flow and circulation building Grey matter in the brain! What is the role of CCSVI Venous Hypertension and proper/improved Cerebrospinal Blood Flow? #CCSVI

Dr Anna Hadjihambi profil fotoğrafı
Dr Anna Hadjihambi1 yıl önce

This is wonderful work! I am looking for a vascular expert collaborator for a recently funded project. Would love to learn from you if you are open to

Andy Shih profil fotoğrafı
Andy Shih2 yıl önce

@AmrnMughal Thank you Amreen! Also, I see you have started your new lab! You deserve the REAL congrats! Happy to talk imaging and veins/venules in the future.

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