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What makes cerebral white matter more vulnerable with age? In this mouse study, we show that large and rare venules are bottlenecks for blood flow in the white matter. Deep branches of these venules are constricted with age, leading to reduced blood flow.

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Andy Shih

1,799 subscribers

33,287 Aufrufe • vor 2 Jahren •via X (Twitter)

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Profilbild von Andy Shih
Andy Shihvor 2 Jahren

An epic study by Stefan Stamenkovic and Nicolas Weiterman, with collaborators @franca_schmid (in silico modeling), Jack Waters, Kevin Takasaki from @AllenInstitute (3-photon), @HannahCBennett7 @yongsookimlab (light-sheet imaging), @stephkbeee @sosamariaj @JennyYuandongLi

Profilbild von Hu Lab
Hu Labvor 2 Jahren

Beautiful!

Profilbild von Georgia Panagiotakos
Georgia Panagiotakosvor 2 Jahren

Beautiful imaging as always — looking forward to reading! Congrats Andy and team! 👏

Profilbild von Osama Harraz
Osama Harrazvor 2 Jahren

Congratulations to you and the team! Christmas tree cerebral vessels!

Profilbild von Lu Liu
Lu Liuvor 2 Jahren

Very cool study

Profilbild von Meier Lowenthal
Meier Lowenthalvor 2 Jahren

inflammation constricting glymphatic clearance causing an accumulation of protein waste?

Profilbild von Damien Levard.
Damien Levard.vor 2 Jahren

Congratulations ! Very interesting study and gorgeous 2photons images

Profilbild von Martin S. Matko
Martin S. Matkovor 2 Jahren

Supplying Oxygen and Nutrients to every Cell blood flow and circulation building Grey matter in the brain! What is the role of CCSVI Venous Hypertension and proper/improved Cerebrospinal Blood Flow? #CCSVI

Profilbild von Dr Anna Hadjihambi
Dr Anna Hadjihambivor 1 Jahr

This is wonderful work! I am looking for a vascular expert collaborator for a recently funded project. Would love to learn from you if you are open to

Profilbild von Andy Shih
Andy Shihvor 2 Jahren

@AmrnMughal Thank you Amreen! Also, I see you have started your new lab! You deserve the REAL congrats! Happy to talk imaging and veins/venules in the future.

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