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While Silicon Valley obsesses over AGI, Mistral AI is betting that big enterprises and sovereign nations will want to own, not rent, their intelligence My conversation with co-founder & CTO Timothee Lacroix (Timothee Lacroix), for his first US podcast ever Was reminded during this conversation that Mistral is barely...

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Matt Turck

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64,450 Aufrufe • vor 6 Monaten •via X (Twitter)

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The end of coding? *Epic* conversation with Guillermo Rauch of Vercel on vibe coding, MCP, agents and building products in the AI era. (00:00) - Intro: Guillermo's Story (02:08) - What is v0 and Why Did It Take Off So Fast? (04:10) - Building a hit product with < people (07:51) - Cursor, Replit, etc: v0 vs Other AI Coding Tools (10:35) - Everyone can cook - What is Vibe Coding? (17:05) - Is v0 Just Frontend? Moving Toward Full Stack 19:40 - How to Become a Great Vibe Coder (23:35) - A GUI for AI: The Future of Interfaces (29:46) - Developer Love vs Agent Love (33:41) - The Importance of Taste in the AI Era (39:10) - MCP: The Protocol for AI-to-AI Communication (43:11) - Security and the Risks of Agentic Web (45:25) - Are Enterprises Ready for the Agentic Future? (49:42) - Building a Data Flywheel (56:06) - The Vercel AI Cloud: From Pixels to Tokens (1:10:14) - Adapting to a Non-Developer Persona (1:13:47) - Retention, Margins, and the Business of AI (1:16:51) - The Secret Behind Vercel Last Year Growth (1:24:15) - The importance of Online Presence (1:30:49) - Everything, Everywhere, All at Once: Keeping your Sanity as a CEO (1:34:59) - Guillermo's Advice to Younger Self
1:45:40

The end of coding? *Epic* conversation with Guillermo Rauch of Vercel on vibe coding, MCP, agents and building products in the AI era. (00:00) - Intro: Guillermo's Story (02:08) - What is v0 and Why Did It Take Off So Fast? (04:10) - Building a hit product with < people (07:51) - Cursor, Replit, etc: v0 vs Other AI Coding Tools (10:35) - Everyone can cook - What is Vibe Coding? (17:05) - Is v0 Just Frontend? Moving Toward Full Stack 19:40 - How to Become a Great Vibe Coder (23:35) - A GUI for AI: The Future of Interfaces (29:46) - Developer Love vs Agent Love (33:41) - The Importance of Taste in the AI Era (39:10) - MCP: The Protocol for AI-to-AI Communication (43:11) - Security and the Risks of Agentic Web (45:25) - Are Enterprises Ready for the Agentic Future? (49:42) - Building a Data Flywheel (56:06) - The Vercel AI Cloud: From Pixels to Tokens (1:10:14) - Adapting to a Non-Developer Persona (1:13:47) - Retention, Margins, and the Business of AI (1:16:51) - The Secret Behind Vercel Last Year Growth (1:24:15) - The importance of Online Presence (1:30:49) - Everything, Everywhere, All at Once: Keeping your Sanity as a CEO (1:34:59) - Guillermo's Advice to Younger Self

Matt Turck

86,153 Aufrufe • vor 1 Jahr

Why AI Progress Suddenly Feels Real - my conversation with Yann Dubois, who co-leads the Post-Training Frontiers team at OpenAI 00:00 - Intro 01:30 - Why recent AI progress feels like a step function 04:13 - Model reliability & the emotional rollercoaster of shipping GPT-5.5 07:33 - How OpenAI structures vertical and horizontal teams 09:49 - Improving model efficiency and test-time compute 12:32 - Yann's journey from Switzerland to OpenAI 15:37 - Reasoning in 2026: Real-world utility vs verifiable rewards 18:34 - GPT-5.5 Thinking vs Pro: Scaling test-time compute 20:09 - How reasoning models become more efficient 23:23 - Pre-training scaling and overcoming the data wall 27:03 - Multimodal data, synthetic data, and embodied AI 31:05 - Demystifying mid-training and post-training 37:21 - Does RL create new capabilities in AI? 38:53 - The challenges and frontier of scaling RL 43:09 - Is building AI models a craft or a strict science 48:21 - How AI models generalize across different domains 54:18 - How reinforcement learning cures AI hallucinations 56:04 - Negative generalization and conflicting instructions 58:05 - Can RL scale to law, medicine, and the broader economy? 1:00:19 - The evaluation bottleneck and Model as a Judge 1:04:21 - Continuous AI progress & continual learning 1:08:49 - Will foundation models eat the agent harness 1:11:23 - Why startups should focus on the last mile of AI
1:13:56

Why AI Progress Suddenly Feels Real - my conversation with Yann Dubois, who co-leads the Post-Training Frontiers team at OpenAI 00:00 - Intro 01:30 - Why recent AI progress feels like a step function 04:13 - Model reliability & the emotional rollercoaster of shipping GPT-5.5 07:33 - How OpenAI structures vertical and horizontal teams 09:49 - Improving model efficiency and test-time compute 12:32 - Yann's journey from Switzerland to OpenAI 15:37 - Reasoning in 2026: Real-world utility vs verifiable rewards 18:34 - GPT-5.5 Thinking vs Pro: Scaling test-time compute 20:09 - How reasoning models become more efficient 23:23 - Pre-training scaling and overcoming the data wall 27:03 - Multimodal data, synthetic data, and embodied AI 31:05 - Demystifying mid-training and post-training 37:21 - Does RL create new capabilities in AI? 38:53 - The challenges and frontier of scaling RL 43:09 - Is building AI models a craft or a strict science 48:21 - How AI models generalize across different domains 54:18 - How reinforcement learning cures AI hallucinations 56:04 - Negative generalization and conflicting instructions 58:05 - Can RL scale to law, medicine, and the broader economy? 1:00:19 - The evaluation bottleneck and Model as a Judge 1:04:21 - Continuous AI progress & continual learning 1:08:49 - Will foundation models eat the agent harness 1:11:23 - Why startups should focus on the last mile of AI

Matt Turck

100,966 Aufrufe • vor 2 Monaten

When Mudith Jayasekara and I met Gabe Pereyra, we were expecting just another vanilla intro call and instead had the best yarn about research, the state of LLMs, and where intelligence is actually heading. It's rare to meet a founder this deep in the weeds who's also building for one of the most important verticals in this new age of intelligence So it was awesome to sit down with Gabe for an extended discussion on what it take to build agents that can reliably complete work over hours, days, or even longer? We talked about why agents today struggle with search and long context windows and how techniques like KV-cache compaction, synthetic data, and continual learning could help. 0:00 Introduction 0:36 Getting legal agents to review the whole data room 2:08 Data rooms larger than any context window 5:28 How far open-source models can go 7:58 Where specialist models fit in legal AI 10:59 Training legal models when client data is off-limits 13:06 Teaching a model how a law firm works 13:59 What belongs in context vs. model weights 15:36 From firm-wide AI to a model for every lawyer 18:37 What training adds beyond retrieving the right cases 20:26 Why context windows have plateaued 24:01 How models could learn continuously on the job 26:12 Can AI recursively improve AI research? 27:07 Research agents can run experiments but not choose them 30:00 Why open-ended research is hard to train 33:47 Why deployment, not intelligence, is the bottleneck 35:08 The cost of frontier intelligence 36:59 Different neolabs, different paths to intelligence 39:26 Using open datasets to compare research methods 41:13 Conclusion
41:50

When Mudith Jayasekara and I met Gabe Pereyra, we were expecting just another vanilla intro call and instead had the best yarn about research, the state of LLMs, and where intelligence is actually heading. It's rare to meet a founder this deep in the weeds who's also building for one of the most important verticals in this new age of intelligence So it was awesome to sit down with Gabe for an extended discussion on what it take to build agents that can reliably complete work over hours, days, or even longer? We talked about why agents today struggle with search and long context windows and how techniques like KV-cache compaction, synthetic data, and continual learning could help. 0:00 Introduction 0:36 Getting legal agents to review the whole data room 2:08 Data rooms larger than any context window 5:28 How far open-source models can go 7:58 Where specialist models fit in legal AI 10:59 Training legal models when client data is off-limits 13:06 Teaching a model how a law firm works 13:59 What belongs in context vs. model weights 15:36 From firm-wide AI to a model for every lawyer 18:37 What training adds beyond retrieving the right cases 20:26 Why context windows have plateaued 24:01 How models could learn continuously on the job 26:12 Can AI recursively improve AI research? 27:07 Research agents can run experiments but not choose them 30:00 Why open-ended research is hard to train 33:47 Why deployment, not intelligence, is the bottleneck 35:08 The cost of frontier intelligence 36:59 Different neolabs, different paths to intelligence 39:26 Using open datasets to compare research methods 41:13 Conclusion

Charlie O'Neill

91,088 Aufrufe • vor 24 Tagen

My conversation with OpenAI co-founder Greg Brockman This is the most detailed first-person account of the 72 hours after Sam Altman was fired. We also go deep on what comes next: the global race to AGI, why ChatGPT stopped showing reasoning, how much of OpenAI's own code is now written by AI ("it's hard to know what percent is not"), and the untold story of how OpenAI actually started in 2015. 00:00:00 Introduction 00:00:49 Meeting Sam Altman and Starting OpenAI 00:02:40 Building the Founding Team 00:04:25 DeepMind's Lead Over OpenAI 00:04:54 Changing OpenAI to a For-Profit Model 00:06:05 Breakthrough Moments at OpenAI 00:08:22 What Dota 2 Meant for OpenAI 00:10:04 Reasoning Versus Prediction 00:11:59 Tensions Grow at OpenAI 00:15:44 Sam Altman's Firing 00:17:49 Greg Quits OpenAI 00:19:56 Sam Explores Deal with Microsoft's Satya 00:20:28 Petition for Altman's Return 00:23:43 Ilya Sutskever Leaves OpenAI 00:24:59 Lessons Learned after Sam Ousting 00:28:22 The Thing Ilya Said that Greg Can't Forget 00:32:22 Is AI Going Parabolic? 00:33:24 How Much of OpenAI's Code is Written by AI? 00:36:21 Do AI Chatbots Tell Us What We Want to Hear? 00:38:06 The Global AI Race to Reach AGI 00:38:40 What Happens if US Doesn't Reach AGI First? 00:39:49 Are Countries Stealing AI Advancements? 00:40:38 Why ChatGPT No Longer Shows Reasoning 00:41:47 The Finite Constraints of Compute 00:43:38 On Investing Early in Data Centers 00:46:31 The Future of Data Center Specialization 00:47:52 How to Decide Whose Queries to Serve 00:49:08 OpenAI on Consumer vs Enterprise Models 00:53:05 Data Centers in Space? 01:00:56 What Should AI Regulation Look Like? 01:04:33 The Future of AI-Powered Entrepreneurship 01:04:44 AI and Job Loss 01:07:15 The Skills Young People Should Invest In 01:11:30 What Does Success Look Like For You? Full episode on X below. Also find it on: • YouTube: • Spotify: • Apple:
1:11:41

My conversation with OpenAI co-founder Greg Brockman This is the most detailed first-person account of the 72 hours after Sam Altman was fired. We also go deep on what comes next: the global race to AGI, why ChatGPT stopped showing reasoning, how much of OpenAI's own code is now written by AI ("it's hard to know what percent is not"), and the untold story of how OpenAI actually started in 2015. 00:00:00 Introduction 00:00:49 Meeting Sam Altman and Starting OpenAI 00:02:40 Building the Founding Team 00:04:25 DeepMind's Lead Over OpenAI 00:04:54 Changing OpenAI to a For-Profit Model 00:06:05 Breakthrough Moments at OpenAI 00:08:22 What Dota 2 Meant for OpenAI 00:10:04 Reasoning Versus Prediction 00:11:59 Tensions Grow at OpenAI 00:15:44 Sam Altman's Firing 00:17:49 Greg Quits OpenAI 00:19:56 Sam Explores Deal with Microsoft's Satya 00:20:28 Petition for Altman's Return 00:23:43 Ilya Sutskever Leaves OpenAI 00:24:59 Lessons Learned after Sam Ousting 00:28:22 The Thing Ilya Said that Greg Can't Forget 00:32:22 Is AI Going Parabolic? 00:33:24 How Much of OpenAI's Code is Written by AI? 00:36:21 Do AI Chatbots Tell Us What We Want to Hear? 00:38:06 The Global AI Race to Reach AGI 00:38:40 What Happens if US Doesn't Reach AGI First? 00:39:49 Are Countries Stealing AI Advancements? 00:40:38 Why ChatGPT No Longer Shows Reasoning 00:41:47 The Finite Constraints of Compute 00:43:38 On Investing Early in Data Centers 00:46:31 The Future of Data Center Specialization 00:47:52 How to Decide Whose Queries to Serve 00:49:08 OpenAI on Consumer vs Enterprise Models 00:53:05 Data Centers in Space? 01:00:56 What Should AI Regulation Look Like? 01:04:33 The Future of AI-Powered Entrepreneurship 01:04:44 AI and Job Loss 01:07:15 The Skills Young People Should Invest In 01:11:30 What Does Success Look Like For You? Full episode on X below. Also find it on: • YouTube: • Spotify: • Apple:

Shane Parrish

450,952 Aufrufe • vor 3 Monaten

AI INTERVIEW: OPENAI'S SECRET WEAPON AI agents are no longer just hype—they're here to revolutionize automation, Web3, and beyond. SwarmNode.ai is building a serverless AI agent platform for scalability, efficiency, and real-world impact. In this exclusive interview, he reveals how AI swarms can outperform single models, why OpenAI’s Operator is just the beginning, and how crypto is fueling AI innovation. Plus, he breaks down DeepSeek’s game-changing AI breakthrough, the future of agent monetization, and why serverless AI could be the next frontier in automation. 01:37 – From Engineering to AI: The journey into artificial intelligence. 02:43 – The GPT-3 Moment: How OpenAI’s tech pulled him in. 04:10 – AI’s Biggest Challenge: Why real-world use cases lag behind. 05:05 – OpenAI’s Operator: Why it’s “rudimentary” (for now). 06:25 – Crypto & AI: How tokens help bootstrap AI startups. 08:15 – Can You Bootstrap a Startup with a Token? The trade-offs. 09:56 – 90% of AI Token Holders Don’t Use the Product—Does It Matter? 11:18 – What is SwarmNode?: AI agents, hosted serverlessly. 14:23 – AI Swarms: Why multiple agents outperform single models. 16:08 – What is a Swarm? A simple definition of collaborative AI. 17:32 – “How Can I Make Money with AI?”: Real-world use cases. 18:41 – AI Bounties: Hiring devs to build your custom agent. 20:50 – The Future of AI Marketplaces: Monetizing pre-built agents. 23:15 – DeepSeek’s Disruption: Why it’s good news for AI. 24:46 – Is SwarmNode Compatible with DeepSeek? How it integrates. 26:17 – SwarmNode vs. AI Launchpads: What makes it different? 27:42 – Why Serverless Matters: Cost savings & efficiency. 29:53 – AI Agents in the Real World: Booking flights, managing workflows, and more. 31:11 – Building SwarmNode for Developers: Why it started as a personal project. 32:27 – Explosive Growth: 200,000 AI agent executions in 5 weeks. 34:41 – Why SwarmNode Agents Aren’t Visible on 𝕏 Yet. 36:46 – Startup Hiring Lessons: Finding top AI talent. 39:15 – Why SwarmNode is Built in Python (and What’s Next). 40:32 – Scaling AI Workloads: Handling traffic surges. 41:42 – AWS & Cost Challenges: The biggest monetization hurdle. 42:58 – 2025: The Year of Mass AI Adoption. 45:22 – Should We Be Worried About AI’s Rapid Growth? 46:46 – The Most Underrated AI Tools Right Now. 47:34 – What’s Next for SwarmNode?: Making AI accessible to everyone.
49:12

AI INTERVIEW: OPENAI'S SECRET WEAPON AI agents are no longer just hype—they're here to revolutionize automation, Web3, and beyond. SwarmNode.ai is building a serverless AI agent platform for scalability, efficiency, and real-world impact. In this exclusive interview, he reveals how AI swarms can outperform single models, why OpenAI’s Operator is just the beginning, and how crypto is fueling AI innovation. Plus, he breaks down DeepSeek’s game-changing AI breakthrough, the future of agent monetization, and why serverless AI could be the next frontier in automation. 01:37 – From Engineering to AI: The journey into artificial intelligence. 02:43 – The GPT-3 Moment: How OpenAI’s tech pulled him in. 04:10 – AI’s Biggest Challenge: Why real-world use cases lag behind. 05:05 – OpenAI’s Operator: Why it’s “rudimentary” (for now). 06:25 – Crypto & AI: How tokens help bootstrap AI startups. 08:15 – Can You Bootstrap a Startup with a Token? The trade-offs. 09:56 – 90% of AI Token Holders Don’t Use the Product—Does It Matter? 11:18 – What is SwarmNode?: AI agents, hosted serverlessly. 14:23 – AI Swarms: Why multiple agents outperform single models. 16:08 – What is a Swarm? A simple definition of collaborative AI. 17:32 – “How Can I Make Money with AI?”: Real-world use cases. 18:41 – AI Bounties: Hiring devs to build your custom agent. 20:50 – The Future of AI Marketplaces: Monetizing pre-built agents. 23:15 – DeepSeek’s Disruption: Why it’s good news for AI. 24:46 – Is SwarmNode Compatible with DeepSeek? How it integrates. 26:17 – SwarmNode vs. AI Launchpads: What makes it different? 27:42 – Why Serverless Matters: Cost savings & efficiency. 29:53 – AI Agents in the Real World: Booking flights, managing workflows, and more. 31:11 – Building SwarmNode for Developers: Why it started as a personal project. 32:27 – Explosive Growth: 200,000 AI agent executions in 5 weeks. 34:41 – Why SwarmNode Agents Aren’t Visible on 𝕏 Yet. 36:46 – Startup Hiring Lessons: Finding top AI talent. 39:15 – Why SwarmNode is Built in Python (and What’s Next). 40:32 – Scaling AI Workloads: Handling traffic surges. 41:42 – AWS & Cost Challenges: The biggest monetization hurdle. 42:58 – 2025: The Year of Mass AI Adoption. 45:22 – Should We Be Worried About AI’s Rapid Growth? 46:46 – The Most Underrated AI Tools Right Now. 47:34 – What’s Next for SwarmNode?: Making AI accessible to everyone.

Mario Nawfal

338,265 Aufrufe • vor 1 Jahr

> "In no scenario is it bad for the US to have frontier-class open-source models." > "Every time there’s a step-function improvement in AI, a human bottleneck emerges alongside it." > "Your desire to be liked sometimes takes away from your desire to do the right thing and seek the truth." > "Every job will get refactored. The people who aren’t AI fluent will have a very hard time finding jobs." Jeetu Patel (Jeetu Patel), President & Chief Product Officer at Cisco sat down for an expansive talk about life and the future. 00:00 AI, jobs, and human potential 00:41 AI cybersecurity and Cisco’s security models 06:33 Why Cisco released the models openly 08:08 Running AI models locally 10:12 Why people are negative about AI 12:14 Will humans always be needed? 14:56 Can curiosity and ambition be taught? 17:12 Passion vs. expertise 19:39 The importance of unlearning 23:52 How to find the truth 26:06 How to get people excited about AI 33:35 How open source affects the AI industry 35:07 Can open-source AI make money? 46:44 Are Chinese open-source models good for the US? 49:55 Should the US restrict Chinese AI models? 53:05 Does open source make humanity safer? 54:11 Advice for people worried about AI
57:20

> "In no scenario is it bad for the US to have frontier-class open-source models." > "Every time there’s a step-function improvement in AI, a human bottleneck emerges alongside it." > "Your desire to be liked sometimes takes away from your desire to do the right thing and seek the truth." > "Every job will get refactored. The people who aren’t AI fluent will have a very hard time finding jobs." Jeetu Patel (Jeetu Patel), President & Chief Product Officer at Cisco sat down for an expansive talk about life and the future. 00:00 AI, jobs, and human potential 00:41 AI cybersecurity and Cisco’s security models 06:33 Why Cisco released the models openly 08:08 Running AI models locally 10:12 Why people are negative about AI 12:14 Will humans always be needed? 14:56 Can curiosity and ambition be taught? 17:12 Passion vs. expertise 19:39 The importance of unlearning 23:52 How to find the truth 26:06 How to get people excited about AI 33:35 How open source affects the AI industry 35:07 Can open-source AI make money? 46:44 Are Chinese open-source models good for the US? 49:55 Should the US restrict Chinese AI models? 53:05 Does open source make humanity safer? 54:11 Advice for people worried about AI

Matthew Berman

68,268 Aufrufe • vor 16 Tagen

Brex co-founder and CEO Pedro Franceschi believes most people still underestimate how much AI will change the way companies are built. AI isn't just another tool, it's a new foundation for building products, teams, and companies. In this episode of Lightcone Podcast, Pedro Franceschi explains why we're only months into a platform shift as significant as the invention of electricity, why the CEO needs to be the chief AI officer, and why founders should rethink what's possible when intelligence is available on demand. 01:13 – How Pedro Became AI-Pilled 04:08 – The Electricity Analogy 05:21 – Free the Claw 06:56 – Making AI Safe for Enterprise 10:57 – Why Most Companies Are Behind 13:09 – AI Teammates, Not Chatbots 14:22 – The Case for Tokenmaxxing 18:24 – The Company of One 20:54 – The One Thing AI Can't Replace 28:06 – Building Customer World Models 32:58 – Rebuilding Brex Around AI 39:02 – The CEO Must Be the Chief AI Officer 43:50 – Building Company AGI 51:43 – Why We're Still So Early
54:06

Brex co-founder and CEO Pedro Franceschi believes most people still underestimate how much AI will change the way companies are built. AI isn't just another tool, it's a new foundation for building products, teams, and companies. In this episode of Lightcone Podcast, Pedro Franceschi explains why we're only months into a platform shift as significant as the invention of electricity, why the CEO needs to be the chief AI officer, and why founders should rethink what's possible when intelligence is available on demand. 01:13 – How Pedro Became AI-Pilled 04:08 – The Electricity Analogy 05:21 – Free the Claw 06:56 – Making AI Safe for Enterprise 10:57 – Why Most Companies Are Behind 13:09 – AI Teammates, Not Chatbots 14:22 – The Case for Tokenmaxxing 18:24 – The Company of One 20:54 – The One Thing AI Can't Replace 28:06 – Building Customer World Models 32:58 – Rebuilding Brex Around AI 39:02 – The CEO Must Be the Chief AI Officer 43:50 – Building Company AGI 51:43 – Why We're Still So Early

Y Combinator

198,105 Aufrufe • vor 2 Monaten

Claude Cowork, Mythos, and the Future of Software: my conversation with Felix Rieseberg, who leads Cowork at Anthropic 00:00 Intro 01:53 Claude Mythos Preview and the “step-function change” 06:16 Why Anthropic is treating Mythos differently 11:19 The real story behind Claude Cowork’s “10-day” build 12:42 Why Anthropic realized Claude Code needed a non-technical version 15:44 What Claude Cowork actually is 17:03 Under the hood: virtual machines, tools, skills 18:36 Where Cowork’s memory actually lives 19:26 How Cowork connects to files, apps, and the internet 20:45 Why Felix thinks the local computer is under-appreciated 24:49 Trust: how do you get users comfortable with AI agents? 28:45 What UX actually means for AI agents 31:27 Anthropic Cowork's roadmap is only one month long 34:12 Building 100 prototypes 35:10 If execution is free, what becomes the bottleneck? 37:25 Does it come down to taste? 40:12 The hardest part of building Claude Cowork 41:43 Advice for founders building AI agents 44:21 SaaSpocalypse: what’s left for software startups 49:30 Where AI agents are going next 51:20 Regulated industries and enterprise adoption 54:15 Hot takes: what's underrated, overrated, and what Felix would build today
58:00

Claude Cowork, Mythos, and the Future of Software: my conversation with Felix Rieseberg, who leads Cowork at Anthropic 00:00 Intro 01:53 Claude Mythos Preview and the “step-function change” 06:16 Why Anthropic is treating Mythos differently 11:19 The real story behind Claude Cowork’s “10-day” build 12:42 Why Anthropic realized Claude Code needed a non-technical version 15:44 What Claude Cowork actually is 17:03 Under the hood: virtual machines, tools, skills 18:36 Where Cowork’s memory actually lives 19:26 How Cowork connects to files, apps, and the internet 20:45 Why Felix thinks the local computer is under-appreciated 24:49 Trust: how do you get users comfortable with AI agents? 28:45 What UX actually means for AI agents 31:27 Anthropic Cowork's roadmap is only one month long 34:12 Building 100 prototypes 35:10 If execution is free, what becomes the bottleneck? 37:25 Does it come down to taste? 40:12 The hardest part of building Claude Cowork 41:43 Advice for founders building AI agents 44:21 SaaSpocalypse: what’s left for software startups 49:30 Where AI agents are going next 51:20 Regulated industries and enterprise adoption 54:15 Hot takes: what's underrated, overrated, and what Felix would build today

Matt Turck

80,718 Aufrufe • vor 4 Monaten

The accidental success of ai16z has catapulted AI agents and their transformational promise into the spotlight. .Shaw (spirit/acc), founder of Eliza Labs, talks about: 🔗 How the Eliza framework brings AI agents to every blockchain 📈 How ai16z is rethinking DAOs and decentralized investing 🌍 The societal shifts AI could bring—and who will control its value Timestamps: 00:00 Intro 03:01 Shaw’s inspiration for launching ai16z 08:45 How AI agents are evolving beyond simple tasks 10:28 The Eliza framework and its open-source impact 13:22 Can AI agents excel at trading? 21:19 Why Eliza works seamlessly across multiple blockchains 24:08 The story behind launching Marc Andreessen as an AI character 35:18 Plans for ai16z’s layer 1 and its future launchpad 40:23 Transforming AI agents into more than just “reply bots” 43:26 Shaw’s vision for AI’s role in shaping human society 49:26 Crypto News Recap Thank you to our sponsors! Kelp Polkadot
49:28

The accidental success of ai16z has catapulted AI agents and their transformational promise into the spotlight. .Shaw (spirit/acc), founder of Eliza Labs, talks about: 🔗 How the Eliza framework brings AI agents to every blockchain 📈 How ai16z is rethinking DAOs and decentralized investing 🌍 The societal shifts AI could bring—and who will control its value Timestamps: 00:00 Intro 03:01 Shaw’s inspiration for launching ai16z 08:45 How AI agents are evolving beyond simple tasks 10:28 The Eliza framework and its open-source impact 13:22 Can AI agents excel at trading? 21:19 Why Eliza works seamlessly across multiple blockchains 24:08 The story behind launching Marc Andreessen as an AI character 35:18 Plans for ai16z’s layer 1 and its future launchpad 40:23 Transforming AI agents into more than just “reply bots” 43:26 Shaw’s vision for AI’s role in shaping human society 49:26 Crypto News Recap Thank you to our sponsors! Kelp Polkadot

Laura Shin

216,192 Aufrufe • vor 1 Jahr

Demis Hassabis (Demis Hassabis) has had one of the most extraordinary careers in tech. He started as a chess prodigy and video game designer at 17 before getting a PhD in neuroscience and going on to found DeepMind. His lab cracked Go, solved protein structure prediction with AlphaFold, and then gave it away free to every scientist on earth. That work won him the 2024 Nobel Prize in Chemistry. Today he leads Google DeepMind, pushing toward the same goal he set as a teenager: AGI. On this special live episode of How to Build the Future, he sat down with YC's Garry Tan to talk about what still needs to happen to get us to AGI, his advice for founders on how to stay ahead of the curve, and what the next big scientific breakthroughs might be. 01:48 — What’s Missing Before We Get To AGI? 03:36 — Why Memory Is Still Unsolved 06:14 — How AlphaGo Shaped Gemini 08:06 — Why Smaller Models Are Getting So Powerful 10:46 — The 1000x Engineer 12:40 — Continual Learning and the Future of Agents 13:32 — Why AI Still Fails at Basic Reasoning 15:33 — Are Agents Overhyped or Just Getting Started? 18:31 — Can AI Become Truly Creative? 20:26 — Open Models, Gemma, and Local AI 22:26 — Why Gemini Was Built Multimodal 24:08 — What Happens When Inference Gets Cheap? 25:24 — From AlphaFold to the Virtual Cells 28:24 — AI as the Ultimate Tool for Science 30:43 — Advice for Founders 33:30 — The AlphaFold Breakthrough Pattern 35:20 — Can AI Make Real Scientific Discoveries? 37:59 — What to Build Before AGI Arrives
40:56

Demis Hassabis (Demis Hassabis) has had one of the most extraordinary careers in tech. He started as a chess prodigy and video game designer at 17 before getting a PhD in neuroscience and going on to found DeepMind. His lab cracked Go, solved protein structure prediction with AlphaFold, and then gave it away free to every scientist on earth. That work won him the 2024 Nobel Prize in Chemistry. Today he leads Google DeepMind, pushing toward the same goal he set as a teenager: AGI. On this special live episode of How to Build the Future, he sat down with YC's Garry Tan to talk about what still needs to happen to get us to AGI, his advice for founders on how to stay ahead of the curve, and what the next big scientific breakthroughs might be. 01:48 — What’s Missing Before We Get To AGI? 03:36 — Why Memory Is Still Unsolved 06:14 — How AlphaGo Shaped Gemini 08:06 — Why Smaller Models Are Getting So Powerful 10:46 — The 1000x Engineer 12:40 — Continual Learning and the Future of Agents 13:32 — Why AI Still Fails at Basic Reasoning 15:33 — Are Agents Overhyped or Just Getting Started? 18:31 — Can AI Become Truly Creative? 20:26 — Open Models, Gemma, and Local AI 22:26 — Why Gemini Was Built Multimodal 24:08 — What Happens When Inference Gets Cheap? 25:24 — From AlphaFold to the Virtual Cells 28:24 — AI as the Ultimate Tool for Science 30:43 — Advice for Founders 33:30 — The AlphaFold Breakthrough Pattern 35:20 — Can AI Make Real Scientific Discoveries? 37:59 — What to Build Before AGI Arrives

Y Combinator

360,550 Aufrufe • vor 3 Monaten

My conversation with Dylan Patel on everything you ever wanted to know about the incredible buildout happening in AI infrastructure This is a whirlwind tour through the companies, deals, models, chips, power sources, partnerships, and people powering AI Dylan is some sort of genius. I wish a version of him existed for every subject. I hope you enjoy this as much as I did. Timestamps: 0:00 Introduction 0:39 The Infinite Money Glitch 4:42 Oracle's Bet on OpenAI 6:06 Nvidia's Strategic Investment and Deal Mechanics 9:17 Why Bigger Models Aren't Always Better 15:07 The Adoption Curve Problem 19:01 The Tokenomics of AI 23:59 Over-Parameterization and Model Learning 28:10 Building Environments for AI Training 32:16 AI in Everyday Life 34:46 The Future of Reasoning and Compute Scaling 44:34 The Spectrum of AI Optimism 46:29 Timeline to AGI 49:25 Talent Wars 58:37 Power Dynamics in the AI Ecosystem 1:18:42 AI for Material Science and Hard Tech 1:22:21 Building Infrastructure 1:29:55 US vs China: Who Really Needs AI to Win? 1:37:42 Favorite AI Bears 1:48:08 Speed Round: Company Impressions 1:55:11 The Death of Traditional SaaS Business Models 2:00:24 The Kindest Thing
2:02:21

My conversation with Dylan Patel on everything you ever wanted to know about the incredible buildout happening in AI infrastructure This is a whirlwind tour through the companies, deals, models, chips, power sources, partnerships, and people powering AI Dylan is some sort of genius. I wish a version of him existed for every subject. I hope you enjoy this as much as I did. Timestamps: 0:00 Introduction 0:39 The Infinite Money Glitch 4:42 Oracle's Bet on OpenAI 6:06 Nvidia's Strategic Investment and Deal Mechanics 9:17 Why Bigger Models Aren't Always Better 15:07 The Adoption Curve Problem 19:01 The Tokenomics of AI 23:59 Over-Parameterization and Model Learning 28:10 Building Environments for AI Training 32:16 AI in Everyday Life 34:46 The Future of Reasoning and Compute Scaling 44:34 The Spectrum of AI Optimism 46:29 Timeline to AGI 49:25 Talent Wars 58:37 Power Dynamics in the AI Ecosystem 1:18:42 AI for Material Science and Hard Tech 1:22:21 Building Infrastructure 1:29:55 US vs China: Who Really Needs AI to Win? 1:37:42 Favorite AI Bears 1:48:08 Speed Round: Company Impressions 1:55:11 The Death of Traditional SaaS Business Models 2:00:24 The Kindest Thing

Patrick OShaughnessy

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